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Pallett Lab UCL @pallettlab.bsky.social · 6h

I’ll start …!

Had the honour of taking my wee one at ~7 months to the @britsocimm.bsky.social congress in Liverpool. Co-carer in tow, complete with funding from a BSI Carers Grant (although partner not pictured) ❤️❤️

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Laura Carter @carterlj.bsky.social · 7d

UKRI #FLF community please help us and spread the word about our @carersinstemm.bsky.social upcoming report launch events.

➡️ First stop The University of Edinburgh on 22nd October

Register here: forms.office.com/pages/respon...

#UKRIFLF #FutureLeadersFellows

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Laura Wolz @laurawolz.bsky.social · 6d

Oh hello there!!! The printed copies of our report have arrived - and I am the chosen Laura to lug them across the country!

So, come and join us in Edinburgh on the 22nd of October for our first @carersinstemm.bsky.social report launch and get your own copy!

forms.office.com/Pages/Respon...

A phot showing a pile of printed report with green cover page. The front title reads The Dual Demands of Academic Travel and Caregiving and shows a graphic of different caregiving situations as well as a wordcloud.

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Astronomer Royal for Scotland | Catherine Heymans @astroroyalscot.bsky.social · 9d

Conventional wisdom says motherhood should wait for tenure as before you land a permanent post, #academia is just not that family friendly🙁

@carersinstemm.bsky.social are calling for change and to celebrate their new report, a Saturday🧵on parenting & academia! 1/9 👩‍🔬🧪🔭⚛️

ℹ️: carersinstemm.co.uk

From 2006. A younger and shell-shocked looking Catherine on a balcony holding a very tiny baby with the mountains of Vancouver in the background. The baby is so new, Catherine still has the pregnant bump.

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Carers In STEMM @carersinstemm.bsky.social · 17d

We are pleased to announce the publication of our STEMM sector-wide survey

The report highlights our findings & suggests recommendations. Now available to download here carersinstemm.co.uk

Please share especially w/ institutions, funders & allies

@laurawolz.bsky.social @carterlj.bsky.social

Screenshot of the front page of the carers in STEMM survey report

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Carers In STEMM @carersinstemm.bsky.social · 17d

Do we have any contacts at a Northern Ireland university? 🙏🧪

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Adrian Liston @labliston.bsky.social · 18d

New #flowcytometery protocol drop from Oliver Burton.

This one is on optimising blocking while preserving signal, in particular how to overcome Fc interactions and dye-dye interactions, and preventing tandem break-down.

currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

Optimization of the Blocking and Signal Preservation Protocol in High‐Parameter Flow Cytometry

High quality input data is the key to successful interpretation of any scientific assay. In flow cytometry, fluorescently-conjugated antibodies allow us to simultaneously measure an incredible range ...

currentprotocols.onlinelibrary.wiley.com

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George Finney @georgeefinney.bsky.social · 21d

🎉 Hot off the press! Our new review on liver resident CD8+ T cells is here - exploring the dual nature of these cells either as protective "Jekyll" 😇 or pathogenic "Hyde” 😈

Dive in to see how the liver microenvironment shapes TRM immunity, pathology & therapeutic potential!

Nature Reviews Gastroenterology & Hepatology @natrevgastrohep.nature.com · 21d

New online! Tissue-resident memory CD8+ T cells: master deciphers of the hepatic environment

Tissue-resident memory CD8+ T cells: master deciphers of the hepatic environment

Nature Reviews Gastroenterology & Hepatology, Published online: 22 September 2025; doi:10.1038/s41575-025-01118-zThis Review provides a comprehensive overview of the role of tissue-resident memory CD8+ T cells in hepatic immune responses, explores their dual function in liver immunoprotection and immunopathology, and discusses their therapeutic potential.

www.nature.com

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Waggoner Lab @labwaggoner.bsky.social · 21d

Review @natrevgastrohep.nature.com
@ucl.ac.uk @pallettlab.bsky.social @brownromeo.bsky.social
Tissue-resident memory CD8+ T cells: master deciphers of the hepatic environment
www.nature.com/articles/s41...

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Pallett Lab UCL @pallettlab.bsky.social · 21d

SOOOOO excited to see this online IN REAL-LIFE!!

Here, we review the latest in hepatic tissue-resident #Tcell biology. We draw on a metaphor proposed by Robert Louis Stevenson [1886] to highlight the fact a cell can manifest different behaviours & actions depending on environmental context 🧪

Nature Reviews Gastroenterology & Hepatology @natrevgastrohep.nature.com · 21d

New online! Tissue-resident memory CD8+ T cells: master deciphers of the hepatic environment

Tissue-resident memory CD8+ T cells: master deciphers of the hepatic environment

Nature Reviews Gastroenterology & Hepatology, Published online: 22 September 2025; doi:10.1038/s41575-025-01118-zThis Review provides a comprehensive overview of the role of tissue-resident memory CD8+ T cells in hepatic immune responses, explores their dual function in liver immunoprotection and immunopathology, and discusses their therapeutic potential.

www.nature.com

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Carers In STEMM @carersinstemm.bsky.social · 22d

🚨We're going on tour!🚨
Join us for 1 of our "Report Launch" networking events: Edinburgh, Manchester, London, or the comfort of your own home!

We will present the 'Carers in STEMM' survey findings, host panel discussions w/ policy markers, EDI advocates & fellow parents/carers.

Spread the word!📣

Poster detailing a series of events hosted by Carers in STEMM in Edinburgh (22nd October), Manchester (13th November) or London (9th December). Events will be hybrid. Poster includes a QR code for registration. Contact us for alternative registration processes.

Poster also details the financial support available to facilitate the full attendance of carers in STEMM or interested, supportive allies

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Adrian Liston @labliston.bsky.social · 24d

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

currentprotocols.onlinelibrary.wiley.com

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Tara Sutherland @drtesutherland.bsky.social · 24d

Aberdeen is hiring - Neuroimmunology Lectureship! Really exciting opportunity to join our supportive, collaborative and multidisciplinary Institute to carry out cutting edge translation research. Not to mention the scenery in the North East of Scotland is amazing www.abdn.ac.uk/jobs/vacanci...

Lecturer in Neuroimmunology, Medicine, Medical Sciences & Nutrition (MED243A) | The University of Aberdeen

Browse and apply for current job openings at the University of Aberdeen across various schools, departments and roles, including admin and academic.

www.abdn.ac.uk

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Journal of Clinical Investigation @jci.org · 25d

MASH: the nexus of metabolism, inflammation and fibrosis

This review by Gregory R Steinberg & colleagues is part of JCI’s ongoing series, Evolving Insights into MASLD and MASH Pathogenesis and Treatment with series editor @hepascott.bsky.social: buff.ly/BgLh6mn

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Christian Frezza @frezzalab.bsky.social · 26d

Peroxisomal metabolism of branched fatty acids regulates energy homeostasis

www.nature.com/articles/s41...

Peroxisomal metabolism of branched fatty acids regulates energy homeostasis - Nature

A UCP1-independent mechanism of thermogenesis involving ATP-consuming metabolism of monomethyl branched-chain fatty acids in peroxisomes is described and a previously unrecognized role for peroxisomes...

www.nature.com

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Reposted by Pallett Lab UCL

Cell - a Cell Press journal @cp-cell.bsky.social · 26d

Now online! Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures

Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures

A pro-fibrotic, mechanosensitive CTHRC1+ fibroblast population derived from creeping fat drives intestinal fibrosis in Crohn’s disease.

dlvr.it

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Waggoner Lab @labwaggoner.bsky.social · 29d

TREM2 macrophages are associated with enhanced response to PD-1 blockade in human hepatocellular carcinoma @miriammerad.bsky.social
www.biorxiv.org/content/10.1...

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Joanna Groom @groomlab.bsky.social · Sep 12

Thrilled to have our latest research @wehi-research.bsky.social published in @natimmunol.nature.com
www.nature.com/articles/s41...

This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social

Thread below...

Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity - Nature Immunology

Dalit, Tan and colleagues provide a multiomic profile of T follicular helper (TFH) cells responses to diverse pathogens, revealing a blueprint for transcriptional flexibility and new tools to interrog...

www.nature.com

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Max Planck Institute for Demographic Research (MPIDR) @mpidr.bsky.social · Sep 8

🚨Job Offer🚨PhD Student Position
The @lshtm.bsky.social, in partnership with the @mpidr.bsky.social is opening an 18-month Research Assistant position, with the successful candidate embarking on a PhD program at LSHTM.
www.demogr.mpg.de/en/career_61...
@ezagheni.bsky.social #phd #jobs #demography

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Waggoner Lab @labwaggoner.bsky.social · Sep 6

CXCR6 promotes dermal CD8+ T cell survival and transition to long-term tissue residence @jimmunol.bsky.social @thelundlab.bsky.social
academic.oup.com/jimmunol/adv...

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Pallett Lab UCL @pallettlab.bsky.social · Sep 5

AND.... some more good news from us, our recent BSc graduate from the lab - Keshav - will be returning in a few weeks as our newly appointed research tech.

WELCOME TO THE TEAM, WELCOME TO THE MADNESS! #TeamScience

Photo of a young Malaysian male, taken in front of some trees

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Pallett Lab UCL @pallettlab.bsky.social · Sep 5

Fantastic to see this out 👏

ScRNAseq data from 77 patients as an atlas for all to use. Used to identify a new subpopulation of pro-inflammatory scar-associated macrophages which promote fibrosis from our friends in the Ramachandran lab. 🧪 #liversky #immunosky

www.biorxiv.org/content/10.1...

A Human Single-cell Atlas Identifies OLR1+ Scar-associated Macrophages as a Therapeutic Target for Chronic Liver Disease

Chronic liver disease (CLD) is a major global healthcare problem. Irrespective of cause, chronic damage to the liver results in fibrosis, which is associated with adverse clinical outcomes. Immune cel...

www.biorxiv.org

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Pallett Lab UCL @pallettlab.bsky.social · Sep 5

Huge congrats to our superstar MRes student who absolutely smashed her project this year, won the best presentation prize and will be off to adventures new very soon for her PhD.

Well done Jacky 👏

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Matthew Freeman @mjafreeman.bsky.social · Sep 1

Are you a postdoc interested in the mechanisms of disease?

Do you have a great record and an exciting vision?

Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.

Deadline 30th September...pass it on!

www.path.ox.ac.uk/work-with-us...

Group Leader Career Development Fellowships - Dunn School

Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?

www.path.ox.ac.uk

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Waggoner Lab @labwaggoner.bsky.social · Aug 29

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines
www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social

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