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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · 6d

Relax, America, There Is Life After Nonstick Pans - from Chef Andrew Zimmerman in @nytimes.com www.nytimes.com/2025/10/08/o...

Opinion | Relax, America, There Is Life After Nonstick Pans

www.nytimes.com

Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · 7d

A Plea From Doctors: Cool It on the Supplements www.nytimes.com/2025/10/07/w...

A Plea From Doctors: Cool It on the Supplements

www.nytimes.com

Reposted by Emil Lou, MD,PhD,FACP

grimmrad 🧬🎼🖼️🏛️ @grimmrad.bsky.social · 7d

Nice and refreshing to see 1/6 Nobel laureates speak out openly against the ongoing destruction of science in the US.

www.yahoo.com/news/article...

Nobel physics laureate says Trump cuts will 'cripple' US research

It was just past 2:00 am when a mysterious number rang Nobel laureate John Clarke, what he deemed "obviously a joke call" that grew increasingly surreal when he heard "a voice from Sweden."- 'Basic sc...

www.yahoo.com

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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · 8d

Performing some team teaching today on Neuroendocrine Cancers by sharing this excellent figure from 2024 expert consensus statement by Drs. Chauhan et al
@cacancerjournal.bsky.social acsjournals.onlinelibrary.wiley.com/doi/10.3322/...

Reposted by Emil Lou, MD,PhD,FACP

Nature Portfolio @natureportfolio.nature.com · 10d

The Nobel prizes will be announced starting Monday, and they’re considered the most famous awards in science. In the past few years, though, a number of other prizes have popped up. Nature examines how these prizes compare with one another. 🧪

These science prizes want to rival the Nobels: how do they compare?

Being named as a Nobel laureate is the ultimate prize for many scientists, but how do other science prizes compare?

go.nature.com

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Reposted by Emil Lou, MD,PhD,FACP

Cancer Grand Challenges @cancergrand.bsky.social · 12d

#CancerGrandChallenges IMAXT in @nature.com:
Using CloneSeq-SV, the team tracked ovarian cancer clones and found:

• Resistant clones often exist from diagnosis
• ctDNA spotted recurrence ~8 months earlier than imaging
• Actionable drivers (e.g. ERBB2) can be revealed

www.nature.com/articles/s41...

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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · 11d

Fascinating bit of the history of #oncology that came to my attention recently:

The world's oldest known cancerous tumor - 1.7 million years! from Swartkrans Cave, South Africa - with rendering included in this 2016 publication
sajs.co.za/article/view...

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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · 11d

#TunnelingNanotubes are membranous extensions of cells that mediate cell contact-dependent intercellular transport of organelles and viruses. In our recent study of SARS-CoV-2 in tissue from patients, we found them in post-infected samples from matched tissue specimens. www.cell.com/iscience/ful...

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Reposted by Emil Lou, MD,PhD,FACP

Nature Reviews Gastroenterology & Hepatology @natrevgastrohep.nature.com · 12d

ICYMI: New online! A neurobiotic sense curbs feeding: a new frontier in gut–brain communication

A neurobiotic sense curbs feeding: a new frontier in gut–brain communication

Nature Reviews Gastroenterology & Hepatology, Published online: 02 October 2025; doi:10.1038/s41575-025-01126-zIn a new study by Liu and colleagues, researchers demonstrated a novel neuroepithelial circuit in colonic neuropod cells through which a molecular pattern from resident microorganisms was relayed to the brain — a ‘neurobiotic sense’ by which the host adjusted its feeding behaviour by monitoring a gut microbial pattern.

www.nature.com

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Reposted by Emil Lou, MD,PhD,FACP

JAMA @jama.com · 17d

Clinicians can enhance patient understanding by using numerical data instead of verbal probabilities, consistent denominators, absolute risk comparisons, and clear context for unfamiliar data types.

ja.ma/46pab9T

JAMA Insights: How to Communicate Medical Numbers. It outlines recommendations for conveying risk, adjusting numerators, communicating probability changes, using visualizations, and providing context, with examples of problematic and preferred communication styles.

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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · 19d

"NCI is the only one of NIH’s 27 institutes and centers whose director is appointed by the president, although the position does not require congressional approval." @science.org

www.science.org/content/arti...

Researchers are relieved at Trump’s likely pick for National Cancer Institute

Harvard physician-scientist Anthony Letai is poised to head world’s largest cancer research agency

www.science.org

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Reposted by Emil Lou, MD,PhD,FACP

c0nc0rdance @c0nc0rdance.bsky.social · 21d

So you're a scientist about to face a government shutdown?

Have you considered becoming a rock star?

It's easy AND profitable! 🎸🧪

Let's list off five scientists who turned rockers:

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Reposted by Emil Lou, MD,PhD,FACP

Nature Portfolio @natureportfolio.nature.com · 21d

There are strong indications that micro- and nanoplastics exposure negatively impacts human health, but a robust evidence base is lacking. A Review in Nature Medicine focuses on the current state of the science. go.nature.com/47H9Q3s #medsky 🧪

This is figure 1, which shows MNP exposure and cellular effects.

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Reposted by Emil Lou, MD,PhD,FACP

Chenxin Li, PhD @chenxinli2.bsky.social · 24d

Re-upping this: For those of you having new students in the lab, I have curated a YouTube playlist on molecular biology: www.youtube.com/playlist?lis...

I usually have my students watch it before I show them how to do it in the lab.

Molecular_Bio - YouTube

www.youtube.com

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Reposted by Emil Lou, MD,PhD,FACP

NEJM.org @nejm.org · 24d

In patients with localized colorectal cancer and PIK3CA hotspot mutations in exon 9 or 20, daily low-dose aspirin resulted in a significantly lower recurrence rate than placebo. Full ALASCCA phase 3 trial results and Research Summary: nej.md/4mpKXNp

#MedSky #Oncology

The New England Journal of Medicine
Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer
A Research Summary based on Martling A et al. | 10.1056/NEJMoa2504650 | Published on September 18, 2025

Visual representations of the patients in the trial and the treatments they were assigned.

Read the full Research Summary at NEJM.org.

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Reposted by Emil Lou, MD,PhD,FACP

Nicholas Weaver @ncweaver.skerry-tech.com · 25d

Why is this horrible for Universities?

Just about everyone who isn't a citizen or green card holder already who's hired for a tenure track faculty position is hired through an H1B and then, after 3-5 years, applies for a green card.

This is literally "No more foreign professors can be hired"

Gergely Orosz @gergely.pragmaticengineer.com · 25d

Those on an H1B cannot return to the US from tomorrow (Sunday) unless paying $100K. This is an out-of-the blue presidential action. We’ll see software engineers stranded abroad.

One easy to predict outcome: those on US visas will travel less… for work, for conferences etc.

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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · 25d

Thank you - much of that is to be determined; but one thing we discovered is that for immunosuppressed patients with cancer and transplant, severe reactions to COVID-19 infection mirrored Graft-vs-Host disease or transplant rejection, so physicians in this field will need to be aware of that aspect.

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Reposted by Emil Lou, MD,PhD,FACP

Sanford Burnham Prebys NCI-Designated Cancer Center @sbpcancercenter.bsky.social · 28d

Today 62 National Cancer Institute (NCI)-Designated Cancer Centers released a statement reinforcing the importance of HPV vaccination.

HPV vaccination is safe and protects against six types of cancer – including oropharyngeal, cervical, and anal cancers.

#HPVvaccine #HPVvax #EndHPVCancers

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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · Sep 15

Precision nutrition, microbiome, viral reservoirs…and more!

Check out Episode 2 of our Only Oncologists in the Building videocast and smash that Subscribe button! With Drs. @shrutipatelmd.bsky.social & @shaalanbeg.bsky.social

www.youtube.com/watch?v=kSLe...
#oncology #video #podcast #YouTube

Precision nutrition, microbiome and viral reservoirs.

YouTube video by Only Oncologists In the Building

www.youtube.com

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Reposted by Emil Lou, MD,PhD,FACP

Eric Topol @erictopol.bsky.social · Sep 13

"We will never know what diseases might have been cured or what advances in technology might have been invented had the lights not gone out in the labs."
www.nytimes.com/2025/09/08/o...

Opinion | We Are Watching a Scientific Superpower Destroy Itself

www.nytimes.com

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Reposted by Emil Lou, MD,PhD,FACP

Cell Press @cellpress.bsky.social · Sep 10

Special issue presented by @cp-neuron.bsky.social on cancer neuroscience⚡🧠 www.cell.com/neuron/issue...

The cover depicts how tumors and the nervous system interact, reciprocally influencing each other's biology. This dynamic crosstalk can modify not only cancer progression and metastasis but also host behavior.

Cover design and illustration by Naola Leconte, Cell Press.

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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · Sep 11

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Emil Lou, MD,PhD,FACP @cancerassassin1.bsky.social · Sep 10

From our U of MN Medical School research team: press release highlighting our recent publication in @cellpress.bsky.social journal @cp-iscience.bsky.social w/implications for Long COVID in immunocompromised patients with cancer and transplant:

med.umn.edu/news/researc...
#COVID #LongCOVID

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Reposted by Emil Lou, MD,PhD,FACP

ASM @asm.org · Sep 3

As national medical, scientific, public health and patient organizations, we call for the resignation of HHS Secretary Robert F. Kennedy Jr. to ensure the health of the American people. Read our statement: asm.org/press-releas...

Joint Statement Calling for Secretary Kennedy Resignation

The American Society for Microbiology released a joint statement calling for the resignation of HHS Secretary Robert F. Kennedy Jr.

asm.org

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Reposted by Emil Lou, MD,PhD,FACP

Dr Elisa Perego @elisaperego78.bsky.social · Aug 26

"the GI epithelium can serve as a long-term COVID reservoir, potentially driving inflammatory syndromes" in the gastrointestinal tract [of immunocompromised cancer patients in the study]

#LongCovid

www.cell.com/iscience/ful...

SARS-CoV-2 infection drives local inflammation of the intestinal epithelium in immunocompromised patients with cancer

Cancer patients undergoing transplantation-based treatments can develop graft-versus-host disease (GVHD), an inflammatory condition that increases mortality risk. In this study, we analyzed three canc...

www.cell.com

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