Had an excellent time at #NWOCHAINS 2025. It's always nice to see the huge diversity in chemistry research in the Netherlands! I am lucky to be part of it.
December 3, 2025 at 8:52 PM
Had an excellent time at #NWOCHAINS 2025. It's always nice to see the huge diversity in chemistry research in the Netherlands! I am lucky to be part of it.
#NWOCHAINS comes to an end with the closing ceremony led by Ioana Ilie (@biosim-lab.bsky.social)!
I had two days of exciting science and learned a lot. Thank you to everyone, who was involved in organizing and who contributed to the program. Congratulations to all winners of the poster prizes!
I had two days of exciting science and learned a lot. Thank you to everyone, who was involved in organizing and who contributed to the program. Congratulations to all winners of the poster prizes!
December 3, 2025 at 8:10 PM
#NWOCHAINS comes to an end with the closing ceremony led by Ioana Ilie (@biosim-lab.bsky.social)!
I had two days of exciting science and learned a lot. Thank you to everyone, who was involved in organizing and who contributed to the program. Congratulations to all winners of the poster prizes!
I had two days of exciting science and learned a lot. Thank you to everyone, who was involved in organizing and who contributed to the program. Congratulations to all winners of the poster prizes!
Interesting talk by Florian Ort from the group of Floris Rutjes at #NWOCHAINS. He talked about the use of #mechanochemistry for solvent-free, racemization-free #peptide #ligation. Exciting applications for #NativeChemicalLigation of insoluble peptides.
#ChemSky #ChemBio #GreenChemistry
#ChemSky #ChemBio #GreenChemistry
December 3, 2025 at 2:46 PM
Interesting talk by Florian Ort from the group of Floris Rutjes at #NWOCHAINS. He talked about the use of #mechanochemistry for solvent-free, racemization-free #peptide #ligation. Exciting applications for #NativeChemicalLigation of insoluble peptides.
#ChemSky #ChemBio #GreenChemistry
#ChemSky #ChemBio #GreenChemistry
Very happy that @marnixroseboom.bsky.social represented our group of the @led3hub.bsky.social with a very well-attended talk at #NWOCHAINS. He reported on his #PhD work on developing #ChemoProteomics technologies to study #CovalentInhibitor target engagement at arginines.
#ChemSky #ChemBio #ProudPI
#ChemSky #ChemBio #ProudPI
December 3, 2025 at 2:28 PM
Very happy that @marnixroseboom.bsky.social represented our group of the @led3hub.bsky.social with a very well-attended talk at #NWOCHAINS. He reported on his #PhD work on developing #ChemoProteomics technologies to study #CovalentInhibitor target engagement at arginines.
#ChemSky #ChemBio #ProudPI
#ChemSky #ChemBio #ProudPI
Interesting talk by Foteini Skoulikopoulou of the group of @armstrongchembio.bsky.social of the @led3hub.bsky.social at #NWOCHAINS. She talked about her research into the synthesis of stable 9-O-acetylated sialic acid mimics with potential applications as #antivirals.
#glycotime #ChemSky #ChemBio
#glycotime #ChemSky #ChemBio
December 3, 2025 at 2:13 PM
Interesting talk by Foteini Skoulikopoulou of the group of @armstrongchembio.bsky.social of the @led3hub.bsky.social at #NWOCHAINS. She talked about her research into the synthesis of stable 9-O-acetylated sialic acid mimics with potential applications as #antivirals.
#glycotime #ChemSky #ChemBio
#glycotime #ChemSky #ChemBio
Interesting talk by Friedrich Förster at #NWOCHAINS. He talked about his group's exciting research into visualizing protein biogenesis at the ER membrane using cryo-electron microscopy and cryo-electron tomography.
www.nature.com/articles/s41...
#cryoEM #proteins #structure
www.nature.com/articles/s41...
#cryoEM #proteins #structure
December 3, 2025 at 2:07 PM
Interesting talk by Friedrich Förster at #NWOCHAINS. He talked about his group's exciting research into visualizing protein biogenesis at the ER membrane using cryo-electron microscopy and cryo-electron tomography.
www.nature.com/articles/s41...
#cryoEM #proteins #structure
www.nature.com/articles/s41...
#cryoEM #proteins #structure
Another great session of #PosterPitches at #NWOCHAINS. We learned about a huge diversity of topics including #SupramoecularAssemblies, #biomarker #sensing, #Ion-selective #membranes, radical #polymerization and #MassSpectrometry.
December 3, 2025 at 2:06 PM
Another great session of #PosterPitches at #NWOCHAINS. We learned about a huge diversity of topics including #SupramoecularAssemblies, #biomarker #sensing, #Ion-selective #membranes, radical #polymerization and #MassSpectrometry.
@seanmckenna.bsky.social represented the group of @sebastianpomplun.bsky.social and the @led3hub.bsky.social with an exciting talk at #NWOCHAINS. He talked about using a combination of in silico screening and semi-automated synthesis to accelerate #DrugDiscovery.
#ChemSky #ChemBio
#ChemSky #ChemBio
December 3, 2025 at 1:59 PM
@seanmckenna.bsky.social represented the group of @sebastianpomplun.bsky.social and the @led3hub.bsky.social with an exciting talk at #NWOCHAINS. He talked about using a combination of in silico screening and semi-automated synthesis to accelerate #DrugDiscovery.
#ChemSky #ChemBio
#ChemSky #ChemBio
Excited that Yorick van Aalst represented our group of the @led3hub.bsky.social with a talk at #NWOCHAINS. He talked about mining #AlphaFold structures of the entire proteome for pockets and using this information to prioritize hits from #Chemoproteomic screens.
#ChemSky #ChemBio #ProudPI
#ChemSky #ChemBio #ProudPI
December 3, 2025 at 1:55 PM
Excited that Yorick van Aalst represented our group of the @led3hub.bsky.social with a talk at #NWOCHAINS. He talked about mining #AlphaFold structures of the entire proteome for pockets and using this information to prioritize hits from #Chemoproteomic screens.
#ChemSky #ChemBio #ProudPI
#ChemSky #ChemBio #ProudPI
Exciting talk by Charalampos Ntallis from the group of Markus Weingarth at #NWOCHAINS. He talked about his exciting research into using solid-state #NMR to understand the interaction between the last resort #antibiotic #polymyxin and #LPS on the molecular level.
December 3, 2025 at 1:50 PM
Exciting talk by Charalampos Ntallis from the group of Markus Weingarth at #NWOCHAINS. He talked about his exciting research into using solid-state #NMR to understand the interaction between the last resort #antibiotic #polymyxin and #LPS on the molecular level.
Insightful talk by Bob van Puffelen from the groups of Jeroen Codee and Dima Filippov @leidenadpr.bsky.social of the @led3hub.bsky.social at #NWOCHAINS. He talked about a glycan modification of the bacterial flagellum and how they use synthetic tools to study its biosynthesis.
#ChemSky #ChemBio
#ChemSky #ChemBio
December 3, 2025 at 1:47 PM
Insightful talk by Bob van Puffelen from the groups of Jeroen Codee and Dima Filippov @leidenadpr.bsky.social of the @led3hub.bsky.social at #NWOCHAINS. He talked about a glycan modification of the bacterial flagellum and how they use synthetic tools to study its biosynthesis.
#ChemSky #ChemBio
#ChemSky #ChemBio
Great talk by Cristina Lopez Gallego from the group of Marcellus Ubbink of our @led3hub.bsky.social of @leidenscience.bsky.social at #NWOCHAINS. She talked about the study of second sphere residues and their effect on the structure, dynamics and function of beta-lactamases.
#Biochemistry #Evolution
#Biochemistry #Evolution
December 3, 2025 at 1:33 PM
Great talk by Cristina Lopez Gallego from the group of Marcellus Ubbink of our @led3hub.bsky.social of @leidenscience.bsky.social at #NWOCHAINS. She talked about the study of second sphere residues and their effect on the structure, dynamics and function of beta-lactamases.
#Biochemistry #Evolution
#Biochemistry #Evolution
Insightful talk by Anthe Janssen at #NWOCHAINS. He talked about his research with Dompé in the framework of #ChemistryNL on using #docking and #MachineLearning-assisted re-scoring to better predict compound binding affinity to #kinases.
pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio #DrugDiscovery
pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio #DrugDiscovery
December 3, 2025 at 9:11 AM
Insightful talk by Anthe Janssen at #NWOCHAINS. He talked about his research with Dompé in the framework of #ChemistryNL on using #docking and #MachineLearning-assisted re-scoring to better predict compound binding affinity to #kinases.
pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio #DrugDiscovery
pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio #DrugDiscovery
Amazing talk by Sander Woutersen at #NWOCHAINS. He gave an entertaining talk on his Ig Nobel Prize winning research on using (drunk) worms as a model for active polymers to better understand their exciting properties.
iop.uva.nl/content/news...
www.science.org/doi/10.1126/...
#Chemistry #Polymers
iop.uva.nl/content/news...
www.science.org/doi/10.1126/...
#Chemistry #Polymers
Ig Nobel prize for drunk worms - IoP
Daniel Bonn, Antoine Deblais, Tess Heeremans and Sander Woutersen have won an Ig Nobel prize for their research in which they investigate the behaviour of drunk worms as a particular form of active ma...
iop.uva.nl
December 3, 2025 at 9:06 AM
Amazing talk by Sander Woutersen at #NWOCHAINS. He gave an entertaining talk on his Ig Nobel Prize winning research on using (drunk) worms as a model for active polymers to better understand their exciting properties.
iop.uva.nl/content/news...
www.science.org/doi/10.1126/...
#Chemistry #Polymers
iop.uva.nl/content/news...
www.science.org/doi/10.1126/...
#Chemistry #Polymers
Great talk by Bianca van Tol at #NWOCHAINS. She talked about the development of neutron-encoded ubiquitins and diubiquitins to study the linkage selectivity of E2 enzymes, E3 ligases and deubiquitinating enzymes.
www.nature.com/articles/s41...
#ChemSky #ChemBio #Ubiquitin
www.nature.com/articles/s41...
#ChemSky #ChemBio #Ubiquitin
December 3, 2025 at 9:00 AM
Great talk by Bianca van Tol at #NWOCHAINS. She talked about the development of neutron-encoded ubiquitins and diubiquitins to study the linkage selectivity of E2 enzymes, E3 ligases and deubiquitinating enzymes.
www.nature.com/articles/s41...
#ChemSky #ChemBio #Ubiquitin
www.nature.com/articles/s41...
#ChemSky #ChemBio #Ubiquitin
Great talk by Floor Stevens from the group of @mvdstelt.bsky.social of our @led3hub.bsky.social at #NWOCHAINS. She talked about her research into "Discovery of a novel metabolic pathway for N-acylethanolamines by cytosolic glucosylceramidase 2".
#Chemistry #ChemBio #LipidTime #Glycotime
#Chemistry #ChemBio #LipidTime #Glycotime
December 3, 2025 at 8:56 AM
Great talk by Floor Stevens from the group of @mvdstelt.bsky.social of our @led3hub.bsky.social at #NWOCHAINS. She talked about her research into "Discovery of a novel metabolic pathway for N-acylethanolamines by cytosolic glucosylceramidase 2".
#Chemistry #ChemBio #LipidTime #Glycotime
#Chemistry #ChemBio #LipidTime #Glycotime
Insightful talk by Dieuwertje Streefkerk at #NWOCHAINS. She talked about their synthetic work on stereochemically defined sulfur(VI) electrophiles and their use as #CovalentInhibitors on the example of chymotrypsin inhibition.
onlinelibrary.wiley.com/doi/full/10....
#ChemSky #ChemBio #Electrophiles
onlinelibrary.wiley.com/doi/full/10....
#ChemSky #ChemBio #Electrophiles
December 3, 2025 at 8:50 AM
Insightful talk by Dieuwertje Streefkerk at #NWOCHAINS. She talked about their synthetic work on stereochemically defined sulfur(VI) electrophiles and their use as #CovalentInhibitors on the example of chymotrypsin inhibition.
onlinelibrary.wiley.com/doi/full/10....
#ChemSky #ChemBio #Electrophiles
onlinelibrary.wiley.com/doi/full/10....
#ChemSky #ChemBio #Electrophiles
Exciting talk by Kevin Neumann (@neumannlab.bsky.social) at #NWOCHAINS. He talked about the tetrazine- and triazine-thiol exchange reactions for #bioconjugation and #peptide cyclization. He also discussed their potential application for #CovalentInhibitors.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
December 3, 2025 at 8:39 AM
Exciting talk by Kevin Neumann (@neumannlab.bsky.social) at #NWOCHAINS. He talked about the tetrazine- and triazine-thiol exchange reactions for #bioconjugation and #peptide cyclization. He also discussed their potential application for #CovalentInhibitors.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Great talk by Marta Artola at #NWOCHAINS. She talked about the use of modified sugars as inhibitors and molecular #chaperones in #DrugDiscovery. Great insights into the use of cyclic sulfamates and sulfamidates as reactive groups for #CovalentInhibitors
pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio
pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio
December 3, 2025 at 8:33 AM
Great talk by Marta Artola at #NWOCHAINS. She talked about the use of modified sugars as inhibitors and molecular #chaperones in #DrugDiscovery. Great insights into the use of cyclic sulfamates and sulfamidates as reactive groups for #CovalentInhibitors
pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio
pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio
"Novel Covalent Inhibitors and Where to Find Them"
I was very excited that Madeline Kavanagh, Marc Baggelaar, Rita Petracca and I were awarded a focus session at #NWOCHAINS. We had an amazing program with talks by Marta Artola, Kevin Neumann and Dieuwertje Streefkerkand a panel discussion. (1/3)
I was very excited that Madeline Kavanagh, Marc Baggelaar, Rita Petracca and I were awarded a focus session at #NWOCHAINS. We had an amazing program with talks by Marta Artola, Kevin Neumann and Dieuwertje Streefkerkand a panel discussion. (1/3)
December 3, 2025 at 8:26 AM
"Novel Covalent Inhibitors and Where to Find Them"
I was very excited that Madeline Kavanagh, Marc Baggelaar, Rita Petracca and I were awarded a focus session at #NWOCHAINS. We had an amazing program with talks by Marta Artola, Kevin Neumann and Dieuwertje Streefkerkand a panel discussion. (1/3)
I was very excited that Madeline Kavanagh, Marc Baggelaar, Rita Petracca and I were awarded a focus session at #NWOCHAINS. We had an amazing program with talks by Marta Artola, Kevin Neumann and Dieuwertje Streefkerkand a panel discussion. (1/3)
The poster pitches at #NWOCHAINS were an absolute firework of great #science on #antivirals, #organocatalysis, #MolecularMotors, #EnzymeEngineering, #photocontrol, #odor, #bacteria, #recycling, #batteries, #QuantumDots, #vitrimers, #BoneRegeneration, native #MassSpectrometry and #biomaterials.
December 3, 2025 at 8:16 AM
The poster pitches at #NWOCHAINS were an absolute firework of great #science on #antivirals, #organocatalysis, #MolecularMotors, #EnzymeEngineering, #photocontrol, #odor, #bacteria, #recycling, #batteries, #QuantumDots, #vitrimers, #BoneRegeneration, native #MassSpectrometry and #biomaterials.
Our postdoc Valeria Poggetti @valeriapoggetti.bsky.social presented her work on Nucleophilic Catalysis in Thiophenol-Based Designer Enzymes at #NWOChains
@stratinghinst.bsky.social @rug.nl
@stratinghinst.bsky.social @rug.nl
December 2, 2025 at 5:23 PM
Our postdoc Valeria Poggetti @valeriapoggetti.bsky.social presented her work on Nucleophilic Catalysis in Thiophenol-Based Designer Enzymes at #NWOChains
@stratinghinst.bsky.social @rug.nl
@stratinghinst.bsky.social @rug.nl
Interesting talk by Tobias Erb at #NWOCHAINS. He talked about building complex, artificial enzyme networks that can fix CO2 and produce high value molecules driven e.g. by light or electricity as energy source.
www.science.org/doi/10.1126/...
www.cell.com/joule/fullte...
#ChemSky #ChemBio #Energy
www.science.org/doi/10.1126/...
www.cell.com/joule/fullte...
#ChemSky #ChemBio #Energy
December 2, 2025 at 11:24 AM
Interesting talk by Tobias Erb at #NWOCHAINS. He talked about building complex, artificial enzyme networks that can fix CO2 and produce high value molecules driven e.g. by light or electricity as energy source.
www.science.org/doi/10.1126/...
www.cell.com/joule/fullte...
#ChemSky #ChemBio #Energy
www.science.org/doi/10.1126/...
www.cell.com/joule/fullte...
#ChemSky #ChemBio #Energy
The scientific program of #NWOCHAINS starts with the opening words by Sandra de Keijzer, head of NWO Chemistry and Physics, and Ioana Ilie (@biosim-lab.bsky.social), chair of the programme committee of CHAINS.
#ChemSky #ChemBio #Conferencing
#ChemSky #ChemBio #Conferencing
December 2, 2025 at 10:01 AM
The scientific program of #NWOCHAINS starts with the opening words by Sandra de Keijzer, head of NWO Chemistry and Physics, and Ioana Ilie (@biosim-lab.bsky.social), chair of the programme committee of CHAINS.
#ChemSky #ChemBio #Conferencing
#ChemSky #ChemBio #Conferencing
Two days of connecting the Dutch Academic Community are coming up at #NWOCHAINS.
Yesterday, we already had the New PI meeting and the PI meeting with a lot of great content. (1/8)
#ECR #PI #Chemistry #ChemBio #Connections #NewPI
Yesterday, we already had the New PI meeting and the PI meeting with a lot of great content. (1/8)
#ECR #PI #Chemistry #ChemBio #Connections #NewPI
December 2, 2025 at 7:21 AM
Two days of connecting the Dutch Academic Community are coming up at #NWOCHAINS.
Yesterday, we already had the New PI meeting and the PI meeting with a lot of great content. (1/8)
#ECR #PI #Chemistry #ChemBio #Connections #NewPI
Yesterday, we already had the New PI meeting and the PI meeting with a lot of great content. (1/8)
#ECR #PI #Chemistry #ChemBio #Connections #NewPI