#Digitoxin
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nz-nb.bsky.social
Adding Another Digit to Guideline-Directed Medical Therapy For Heart Failure?

https://www.newsbeep.com/nz/185374/

Quick Takes Digitoxin is beneficial in reducing the combined risk of heart failure (HF) hospitalization and all-cause mortality…
Adding Another Digit to Guideline-Directed Medical Therapy For Heart Failure? - New Zealand News Beep
Quick Takes
www.newsbeep.com
December 15, 2025 at 9:30 PM
ie-news.bsky.social
Adding Another Digit to Guideline-Directed Medical Therapy For Heart Failure?

https://www.europesays.com/ie/234509/

Quick Takes Digitoxin is beneficial in reducing the combined risk of heart failure (HF) hospitalization and all-cause mortality…
Adding Another Digit to Guideline-Directed Medical Therapy For Heart Failure? - Ireland
Quick Takes
www.europesays.com
December 15, 2025 at 8:30 PM
ca-nb.bsky.social
Adding Another Digit to Guideline-Directed Medical Therapy For Heart Failure?

https://www.newsbeep.com/ca/347393/

Quick Takes Digitoxin is beneficial in reducing the combined risk of heart failure (HF) hospitalization and all-cause mortality…
Adding Another Digit to Guideline-Directed Medical Therapy For Heart Failure? - Canada News Beep
Quick Takes
www.newsbeep.com
December 15, 2025 at 8:20 PM
p0llyticks.norden.social.ap.brid.gy
Ein traditionelles Mittel aus dem Fingerhut zeigt neue Stärke: Digitoxin senkt in einer großen Studie das Risiko für Klinikeinweisungen und Todestalle bei Herzschwäche um 18 Prozent. In niedriger Dosierung gilt es als deutlich sicherer als früher angenommen und eröffnet neue […]
Original post on norden.social
norden.social
December 15, 2025 at 12:32 PM
drdavemd.bsky.social
Is the oldest therapy for HF back? RCT shows digitoxin reduces mortality and hospitalization in HFrEF by ~15% www.nejm.org/doi/10.1056/... #cardiosky
Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | NEJM
The therapeutic efficacy of the cardiac glycoside digitoxin in patients with heart failure and reduced ejection fraction is not established. In this international, double-blind, placebo-controlled ...
www.nejm.org
December 9, 2025 at 8:09 PM
herzmedizin.bsky.social
👵👴 #AHA2025: Subanalyse aus DIGIT HF zeigt, dass #Digitoxin auch bei älteren HFrEF-Patienten mit hoher Komorbidität wirken könnte.
📊 Prof. Bauersachs stellte die Daten vor.
🎙️Prof. Aßmus kommentiert die klinischen Implikationen.
➡️ herzmedizin.de/fuer-aerzte-...
#Herzmedizinde #DGK #CardioSky
Digitoxin ist auch bei Älteren wirksam
AHA Congress 2025 | DIGIT-HF: Subanalyse zur Wirksamkeit von Digitoxin bei älteren und jüngeren Personen mit HFrEF. Kommentar von Prof. B. Aßmus.
herzmedizin.de
November 26, 2025 at 1:10 PM
evidencerounds.bsky.social
Is GDMT for heart failure coming full circle?

In a double-blind multicenter trial of advanced HFrEF, digitoxin—a safer digoxin analog not available in the US—reduced both mortality and hospitalizations

A Dutch trial of digoxin is underway, with results expected soon
November 24, 2025 at 4:15 PM
arznei-telegramm.de
#Digitoxin und #Vericiguat: Neues zu Reservemitteln in der #Herzinsuffizienztherapie

Wir ordnen die Ergebnisse der mit öffentlichen Geldern geförderten DIGIT-HF-Studie zu Digitoxin ein sowie der VICTOR-Studie zu Vericiguat.
www.arznei-telegramm.de/html/2025_10...
Digitoxin und ▼Vericiguat: Neues zu Reservemitteln in der Herzinsuffizienztherapie
Wir ordnen die Ergebnisse der mit öffentlichen Geldern geförderten DIGIT-HF-Studie zu Digitoxin ein sowie der VICTOR-Studie zu Vericiguat ein.
www.arznei-telegramm.de
October 20, 2025 at 6:41 AM
jacobgudiol.traningslara.se
Varför drar universitetens presskontor och media till med sådana här rubriker?

Digitoxin, ämnet som ska testas framställs från en blomma. Men det är en process som man givetvis inte kunde utföra på 1700-talet

Så i princip noll relevans

Men det här göder folk som tror på en massa alternativa saker
October 18, 2025 at 7:36 PM
markusathome.bsky.social
Novel developments in the treatment of HFrEF - Prof. Dr. John McMurray (Glasgow, UK)

youtu.be/kK8N-5RkEfc?...

Prof. McMurray discusses new developments in the treatment of HFrEF, focusing on new outcome data for vericiguat and digitoxin from the VICTOR and DIGIT-HF studies.
Novel developments in the treatment of HFREF - Prof. Dr. John McMurray (Glasgow, UK)
YouTube video by MARKUS at HOMe
youtu.be
October 17, 2025 at 6:02 PM
arznei-telegramm.de
Die Oktober-Ausgabe ist erschienen – Themen: #Digitoxin und #Vericiguat: Neues zu Reservemitteln in der #Herzinsuffizienztherapie – Neue Daten zum #RSV-Impfstoff ABRYSVO bei älteren Erwachsenen – Duale #Plättchenhemmung nach #Stent wegen akuter Koronarsyndrome: Wie lange? – u.a.
arznei-telegramm 10/2025 Inhaltsverzeichnis
www.arznei-telegramm.de
October 17, 2025 at 1:12 PM
se-nyheter.bsky.social
1700-talsmedicin prövas mot dödlig cancer – Svensk Farmaci

https://www.europesays.com/se/56274/

Digitoxin, som utvanns ur fingerborgsblomman redan på 1700-talet, har visat sig störa cancercellers energiproduktion. Bild: Jessica Cortez Digitoxin…
1700-talsmedicin prövas mot dödlig cancer – Svensk Farmaci - Sverige
Digitoxin används främst för att behandla hjärtsjukdomar som hjärtsvikt och vissa typer av oregelbunden hjärtrytm, som förmaksflimmer. Ämnet utvinns ur växten
www.europesays.com
October 15, 2025 at 1:33 PM
se-nyheter.bsky.social
Gammal huskur prövas mot dödlig cancer i Skövde

https://www.europesays.com/se/55260/

Forskare i Skövde påbörjar nu, tillsammans med Skaraborgs sjukhus, en klinisk studie för att undersöka om hjärtmedicinen digitoxin,…
Gammal huskur prövas mot dödlig cancer i Skövde - Sverige
Forskare i Skövde påbörjar nu, tillsammans med Skaraborgs sjukhus, en klinisk studie för att undersöka om hjärtmedicinen digitoxin, som ursprungligen utvanns
www.europesays.com
October 14, 2025 at 8:33 AM
medicine.stitches.today
Digitoxin reduces death and hospitalization risk in heart failure patients, outperforming placebo in a substantial clinical trial.

by Bavendiek U, Großhennig A (...) Bauersachs J et 32 al. in N Engl J Med #MedSky

👉 get more here

📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2415471
October 4, 2025 at 6:35 PM
nomad-notmad.bsky.social
Pretty in pink ... but one of them is a killer

#flowers
Pink and red tulips blooming beautifully Pink foxglove flowers are beloved by gardeners and bees, but they contain a deadly poison. Due to the cardiac glycoside digitoxin, in the leaves, flowers and seeds of this plant, it is extremely poisonous to humans and some animals and can be fatal if eaten. All plant parts must be handled with extreme care.
October 2, 2025 at 5:22 AM
nejm.org
DIGIT-HF phase 4 trial: In patients with heart failure and reduced ejection fraction, the efficacy of cardiac glycosides when added to contemporary therapies is unclear. Research findings on the safety and efficacy of digitoxin are summarized in a new Quick Take video. nej.md/3IgL4wO
A visual representation of the DIGIT-HF phase 4 trial, which evaluated the safety and efficacy of digitoxin in patients with heart failure and reduced ejection fraction.
October 1, 2025 at 4:08 PM
nejm.org
In patients with heart failure and reduced ejection fraction who were receiving guideline-directed medical therapy, digitoxin lowered the risk of death or hospitalization for heart failure as compared with placebo. Full DIGIT-HF phase 4 trial results and Research Summary: nej.md/3HQHLfj
The New England Journal of Medicine Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction A Research Summary based on Bavendiek U et al. | 10.1056/NEJMoa2415471 | Published on August 29, 2025 Visual representations of the patients in the trial and the treatments they were assigned. Read the full Research Summary at NEJM.org.
September 28, 2025 at 1:02 PM
thecurbsiders.bsky.social
📰 New Curbsiders Digest! 🥂

From VTE ➡️ VT, this issue covers:

💊 Extended Apixaban for VTE prevention
⚡ Potassium for arrhythmia prevention
❤️ Digitoxin for heart failure in the spotlight

👉 thecurbsiders.com

#MedEd #FOAMed #Cardiology #InternalMedicine #TheCurbsiders
September 26, 2025 at 11:44 PM
johnrossmd.bsky.social
Withering described all the classic toxicities of of high doses of digoxin/digitoxin: "sickness, vomiting, purging, giddiness, confused vision, objects appearing green or yellow...slow pulse, even as slow as 35 in a minute, cold sweats, convulsions, syncope, death"
William Withering, a serious man in periwig and frockcoat
September 26, 2025 at 1:28 PM
johnrossmd.bsky.social
Digoxin (excreted renally) and digitoxin (metabolized by liver) are both derived from foxglove. William Withering described its use in "dropsy" in 1785. While it relieved dyspnea and edema, he noted that it had a narrow therapeutic index: the effective dose was close to that which causes toxicity
Foxglove (Digitalis purpurea): tall spikes of tubular, bell-shaped flowers, usually in shades of purple and pink, with spots on the inside
September 26, 2025 at 1:21 PM
johnrossmd.bsky.social
Old man post: when I was an intern, digoxin was a go-to med for heart failure, but it is all but forgotten today. A new study in @nejm.org found that digitoxin reduced the combined end-point of death or CHF hospitalization in patients maxed out on guideline-directed medical therapy
Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction | NEJM
www.nejm.org
September 26, 2025 at 1:04 PM
nejm.org
New in the September 25, 2025, issue of NEJM:

Digitoxin in Heart Failure with Reduced EF (DIGIT-HF phase 4 trial) nej.md/3HQHLfj

Apixaban for Provoked Venous Thromboembolism (HI-PRO trial) nej.md/4p6tIDo

#MedSky
Images and descriptions of what's new on NEJM.org this week
September 25, 2025 at 3:24 PM
natrevcardiol.nature.com
New online! Benefit of digitoxin therapy for HFrEF #CardioSky
Benefit of digitoxin therapy for HFrEF
Nature Reviews Cardiology, Published online: 11 September 2025; doi:10.1038/s41569-025-01217-zIn the DIGIT-HF trial, treatment with digitoxin in addition to guideline-directed medical therapy reduced the risk of hospitalization for worsening heart failure or all-cause death compared with placebo in patients with heart failure with reduced ejection fraction.
bit.ly
September 11, 2025 at 12:29 PM
katiekalvaitis.bsky.social
Catch up on news from the European Society of Cardiology Congress:

🫀 Digitoxin for HFrEF
🫀 Beta-blockers after heart attack
🫀 New treatments for obstructive + nonobstructive HCM
🫀 Baxdrostat for resistant hypertension
🫀 + more

www.healio.com/news/cardiol...

#ESCCongress @gohealio.bsky.social
European Society of Cardiology
The latest news from the ESC Congress, with physician perspective, researcher interviews and clinician insight.
www.healio.com
September 8, 2025 at 3:27 PM
kardioklick.bsky.social
A lot of competitors for the title „fifth Pilar“ of HF therapy: Elektrophysiologists say it’s PVI, Hannover is rooting for Digitoxin and this paper says Vericiguat. Why not just make it the magnificent 7…?

#cardiosky
September 8, 2025 at 5:38 AM