Cells compete to maintain tissue health. A #research team from #MPZPM, @ijmonod.bsky.social & #NielsBohrInstitute found that force transmission decides the winner, challenging classical #CellCompetition views.

Learn more 👉 mpzpm.mpg.de/news/news-de...

#science #cellbiology

📸 Lucas Anger

Ever wonder how cells in our epithelia fight for space? 🤔

Let's dive into the fascinating world of mechanical cell competition! #EpithelialMechanics

Hello, I am @akshar21.bsky.social and I'll be your guide through this thread on mechanical #CellCompetition

1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition
www.biorxiv.org/content/10.1...
showing it recapitulates much of the embryo 🧵

EXCITED to share our new paper in Nat Commun @natureportfolio.bsky.social "Foxo3-mediated physiological cell competition ensures robust tissue patterning throughout vertebrate development”, identifying a potential marker of cell competition. #zebrafish #cellcompetition
www.nature.com/articles/s41...

Landmark revisit
#Angiogenesis #CellCompetition VEGFR1/2 NOTCH

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

#NatureCellBio 2010
www.nature.com/articles/ncb...