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zebrafish007.bsky.social
Dan 🐟 C
@zebrafish007.bsky.social
1.8K followers 1.7K following 53 posts
Zebrafish, blood and lymphatic vessels, microscopes, imaging, aquaculture, cavefish, 3D printing, science. views my own.
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zebrafish007.bsky.social
Dan 🐟 C @zebrafish007.bsky.social · Nov 11
The first 22 hours of #Zebrafish development. Blood vessels labeled in green #WeinsteinLab 🔬🧪
Reposted by Dan 🐟 C
pjmurphy249.bsky.social
Soliciting recommendations for 3D printers and lab supply blue prints. Please share and RT.
November 21, 2025 at 2:24 AM
Reposted by Dan 🐟 C
zebrafishrock.bsky.social
#KnowYourZDM: In 2019, a 10-year-old patient w/ a life-threatening lymphatic disorder was losing hope. Zebrafish to the rescue! Scientists created zebrafish with the same gene mutation and found a melanoma drug that fixed the fish. Then, doctors used the same drug on the patient to save his life! 🧪
Zebrafish are an excellent model for studying the development and function of blood and lymphatic vessels. Research in zebrafish has even led to treatments for lymphatic disorders in people. This image, taken using a powerful microscope that uses lasers to illuminate the fish, shows blood vessels (magenta) and lymphatic vessels (green) in the eye and head of an anesthetized, 6-week-old, transgenic zebrafish. Credit: Daniel Castranova, National Institute of Child Health and Human Development, NIH
November 20, 2025 at 6:51 PM
Reposted by Dan 🐟 C
siegenthalerlab.bsky.social
Our work out in @devbiol.bsky.social, PDGFra is needed for 🧠 perivascular fibroblast development... ⬇️ perivascular fibroblast = ⬇️ perivascular macrophage...cross-talk? 👀
Led by Hannah Jones @hejcell.bsky.social w/ Kelsey Abrams, Sophia Kim, excited for more projects w/ @fantauzzolab.bsky.social!
Micrscopy images of cleared cerebral brain tissue showing penetrating blood vessels (white) in mice - magenta cells are perivascular fibroblasts and cyan cells are perivascular macrophages - in control mice, both cell types are near the vessel termini by postnatal day 10 but in 'cKO' mice that lack expression of a tyrosine kinase receptor PDGFRa in fibroblasts, both the fibroblasts and macrophages are only partially covering the vessels. From Figure 4 of our paper - https://authors.elsevier.com/a/1m7fa2mzTkyfS
November 20, 2025 at 1:23 PM
Reposted by Dan 🐟 C
auroralkraus.bsky.social
Check out our recent preprint, "Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish."

lnkd.in/gN7z6th4
November 18, 2025 at 2:42 AM
Reposted by Dan 🐟 C
biorxiv-neursci.bsky.social
Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish https://www.biorxiv.org/content/10.1101/2025.11.14.688311v1
November 17, 2025 at 12:16 AM
Reposted by Dan 🐟 C
zebrafishrock.bsky.social
“By performing longitudinal live imaging of intubated adult fish we observe vascular regrowth and immune responses to [meningeal cerebrovascular injuries] over time in the same animal with unprecedented resolution”

New work from #WeinsteinLab at NIH
biorxiv-neursci.bsky.social bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 6d
Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish https://www.biorxiv.org/content/10.1101/2025.11.14.688311v1
November 17, 2025 at 8:11 PM
Reposted by Dan 🐟 C
zebrafishrock.bsky.social
#ZebrafishFunFacts: Using the discarded slide film from his doctoral research, Professor and amateur artist Michael Barresi created a mosaic of an adult #zebrafish.

Learn about his upcoming art installation on human embryos called 'Using Art to Demystify Science': www.smith.edu/news-events/... 🧪
Image of an adult zebrafish using discarded film slides. There are stripes of dark brown and blue capturing the essence of adult zebrafish
November 7, 2025 at 11:24 AM
Reposted by Dan 🐟 C
mdibl.org
Big congratulations to Hannah Somers, Digital Image Analyst at MDI Bio Lab, whose striking visualization of a zebrafish’s brain was named an Image of Distinction in the Nikon Small World competition — and featured by #NationalGeographic!

#researchmatters #microscopymonday #lightsheet 🧪 🤝 🐟🎸 👩‍🔬
MDI Bio Lab’s Hannah Somers’ Image Wins International Recognition
mdibl.org
November 3, 2025 at 3:01 PM
Reposted by Dan 🐟 C
zebrafishrock.bsky.social
Slow-mo video of zebrafish mating. Credit to
@zebrafish007.bsky.social. #ZebrafishZunday 🧪
November 2, 2025 at 8:14 AM
Reposted by Dan 🐟 C
solomonrdavid.bsky.social
Y’all saw it here on Bluesky FIRST.

Trailer for #GarWeek 2025.
JOIN US November 3-7!!!
October 29, 2025 at 9:14 PM
Reposted by Dan 🐟 C
zebrafishrock.bsky.social
#KnowYourZDM: Humans and #zebrafish carrying mutations in VEGFC or its receptor (FLT4) have defects in the formation of their lymphatic systems, which are important for draining lymph back into the circulation system.  As a result, these individuals display severe #lymphedema. 🧪
Humans bearing mutations in vascular endothelial growth factor C (VEGFC) or its receptor tyrosine kinase (FLT4) have defects in the formation of their lymphatic system, which is important for draining interstitial fluid back into the circulatory system. As a consequence, these patients display severe lymphedema (bottom left). In zebrafish, we have generated mutations in vegfc and flt4, both of which are conserved between zebrafish and humans. Like humans, zebrafish larvae also display lymphedema due to a failure to form a complete lymphatic system (bottom right). Credit image and text to Prof. Nathan Lawson @LawsonZFLab https://www.umassmed.edu/lawson-lab/zebrafishmodel/disease-models/
October 26, 2025 at 5:31 PM
Reposted by Dan 🐟 C
zebrafishrock.bsky.social
Endocardium, cells lining the heart chambers, in the beating heart of a two-day-old transgenic #zebrafish. Credit to @anjaliesch.bsky.social & Nikon Small World Competition. #ZebrafishZunday 🧪
October 26, 2025 at 8:06 AM
Reposted by Dan 🐟 C
retof.bsky.social
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
October 6, 2025 at 5:52 PM
Reposted by Dan 🐟 C
solomonrdavid.bsky.social
You’re not ready for gar slime:
October 1, 2025 at 2:33 PM
Reposted by Dan 🐟 C
scadsai.bsky.social
@scadsai.bsky.social training coordinator @haesleinhuepf.bsky.social provided insights into his professional career in the podcast series “The Microscopists.”
If you want to know why he'll never ask biologists for better images again, click here:
🍍 themicroscopists.bitesizebio.com/episodes/rob...
September 30, 2025 at 9:47 AM
Reposted by Dan 🐟 C
dev-journal.bsky.social
Wrong place, right time: Eda drives ectopic teeth formation in fish
This Research Highlight showcases the work from Tyler Square and colleagues: journals.biologists.com/dev/article/...
Eda overexpression causes precocious tooth differentiation in sticklebacks. (A,B) at 9 dpf, Eda OE fish (n=9) demonstrated precocious oral tooth germs relative to control fish (n=10). Images show eGFP from the dlx2b tooth reporter and mCherry from the OE transgene. A’ and B’ show the fish indicated in A and B in greater detail. Black arrowheads indicate pioneer tooth germs. (C) at 12 dpf in WT, pairs of germs are observed on the premaxilla and dentary (black arrowheads), similar to the condition seen in the 9 dpf Eda OE fish, suggesting these represent accelerated endogenous teeth. Sale bars=100 μm.
September 26, 2025 at 12:38 PM
Reposted by Dan 🐟 C
akankshi.bsky.social
Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd
September 26, 2025 at 12:55 PM
Reposted by Dan 🐟 C
pedroprocha.bsky.social
🚨🚨🚨 Please repost
We are looking for postdocs to join our lab at NIH.
Apply:
www.nichd.nih.gov/research/atNICHD/Investigators/rocha/apply
Learn more about training at NIH :
www.training.nih.gov/research-tra...
Job add showing the lab logo and the following text: WHAT WE OFFER Fully-funded fellowships up to five years Opportunity to start your own research program or lead ongoing projects. Large, diverse and extraordinary scientific network at the NIH/Bethesda campus. Working at NIH offers the possibility of living in a diverse, liberal and vibrant city: Washington DC Or in a calm residential area with great schools and good affordable housing: Bethesda and Rockville. WHO YOU ARE You share our enthusiasm for epigenetics, gene regulation, nuclear organization and mouse development. You have PhD-experience in one or more of the following: mouse development, mouse genetics, epigenetics, or computational biology.
September 8, 2025 at 3:15 PM
Reposted by Dan 🐟 C
whitefishlab.bsky.social
Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com)‬ paper, Miranda Hunter (@mrndhntr.bsky.social‬) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2
August 28, 2025 at 3:15 PM
Reposted by Dan 🐟 C
karinayaniv.bsky.social
Happy to see our work, led by @ivanbassi.bsky.social, out today in @jem.org! #Zebrafish help us find new treatments for a #rare_disease affecting #lymphatic vessels! Congrats to all authors and thanks to #MDBRide4Rare, #ODC_UPenn, @erc.europa.eu for support @weizmanninstitute.bsky.social
August 21, 2025 at 4:52 PM
Reposted by Dan 🐟 C
daniellebeckman.bsky.social
Check this neuron infected with #SARSCoV2 being attacked by a microglia. Is this process beneficial or detrimental? Do we want therapies to inhibit microglia activation/neuroinflammation, but what if it means more neurons infecting other neurons? Neurovirology is fascinating! #FluorescenceFriday
August 8, 2025 at 7:21 PM
zebrafish007.bsky.social
💯
ritastrack.bsky.social Rita Strack @ritastrack.bsky.social · Aug 8
Microscopy most especially. To be the first human to ever lay eyes on something. What a feeling.
redpenblackpen.bsky.social RedPen/BlackPen @redpenblackpen.bsky.social · Aug 8
Really just had something like this feeling this afternoon. It’s the high that keeps you coming back for more
August 8, 2025 at 1:34 AM
Reposted by Dan 🐟 C
hankgreen.bsky.social
mRNA tech is some of the coolest, most powerful, most promising scifi shit humans are currently doing. They are being investigated to help with cancers, autoimmune diseases, M.S., stroke recovery, heart disease, diabetes, arthritis, and high cholesterol.
August 6, 2025 at 3:59 AM
Reposted by Dan 🐟 C
fsantoriello.bsky.social
New short story from my postdoc in the Bassler lab is up on bioRxiv!

Turns out our favorite quorum sensing responsive phage VP882 is a member of a larger family of phages that is distributed across multiple bacterial species and can eavesdrop on a universally conserved autoinducer.

#PhageSky 🦠🧫
biorxiv-microbiol.bsky.social bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Jul 30
A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species https://www.biorxiv.org/content/10.1101/2025.07.30.667625v1
July 31, 2025 at 10:18 AM
Reposted by Dan 🐟 C
jeffreyafarrell.bsky.social
Hey friends - Daniocell is experiencing a temporary outage right now. The NICHD server it is hosted on got dropped from the NIH’s firewall list & so currently can’t be accessed outside the NIH. The relevant IT teams are working to resolve it. Sorry for any inconvenience. It’ll be back soon!!
July 29, 2025 at 9:58 PM