Tim Pullen
Tim Pullen
@tjpullen.bsky.social
Senior Lecturer in Biochemistry Education @KingsCollegeLondon.bsky.social
Interested in innovative teaching and researching type 2 diabetes and islet biology. Opinions are my own.
Reposted by Tim Pullen
A huge step forward for cell replacement therapy for #T1D @NEJM

Vertex clinical trials for zimislecel

www.nejm.org/doi/full/10....
Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM
Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...
www.nejm.org
June 21, 2025 at 9:17 AM
Reposted by Tim Pullen
Too much protein in the diet appears to carry a risk of atherosclerotic heart disease secondary to leucine's effect. An important report considering recent advocacy for very high-protein diets.
@natmetabolism.nature.com
nature.com/articles/s42...
May 25, 2025 at 10:44 PM
Reposted by Tim Pullen
⛵ SailLink launches on Sat 5th April! Sail-powered channel crossings from Dover to Boulogne-sur-Mer. Catamaran "Echoes" sets sail at 10am heading for the French coast – be part of the inaugural crossing by booking here: www.saillink.co.uk/book-now/
March 12, 2025 at 3:31 PM
Reposted by Tim Pullen
OK, every year I try to explain to my students how LLMs work, and every year I have to do a big trawl for good resources and activities. Here's this year's haul of *introductory* materials. (In-class activities + visualizations, not so much readings.)
March 6, 2025 at 6:42 PM
Reposted by Tim Pullen
Excited to share our publication in @cp-iscience.bsky.social
Islet single-cell transcriptomic profiling during obesity-induced beta cell expansion in female mice #IMM @uthealthhouston.bsky.social @bcmhouston.bsky.social 🧵 www.cell.com/iscience/ful...
Islet single-cell transcriptomic profiling during obesity-induced beta cell expansion in female mice
Targeting beta cell proliferation is an appealing approach to restore glucose control in type 1 diabetes. However, the underlying mechanisms of beta cell proliferation remain incompletely understood, ...
www.cell.com
February 20, 2025 at 5:36 PM
Reposted by Tim Pullen
Sign up for the King's AI Institute public newsletter :https://forms.office.com/pages/responsepage.aspx?id=FM9wg_MWFky4PHJAcWVDVl9i9UpacDdIsYMl40t_1cFUNUdKT0tSR09FRlZZWjk0WFgzUDdaR1NCRi4u&route=shorturl
February 2, 2025 at 3:06 PM
Reposted by Tim Pullen
Did you know? The top three overseas destinations for UK travellers are Spain, France and Italy – all easily accessible without flying:

🇪🇸 www.seat61.com/Spain.htm
🇫🇷 www.seat61.com/France.htm
🇮🇹 www.seat61.com/Italy.htm

(Thanks @seatsixtyone.bsky.social!)
January 16, 2025 at 12:29 PM
Reposted by Tim Pullen
Super pleased to share our latest publication “Generative AI in Higher Education: Balancing Innovation and Integrity” how #GenAI is reshaping learning, assessment, emphasising the need for ethical frameworks to maintain academic integrity.

@nigelfrancis.bsky.social & Sue Jones

tinyurl.com/y384wfvw
January 13, 2025 at 3:21 PM
Reposted by Tim Pullen
Dear meeting organizers:

Picking the same senior PIs to keynote/give talks at meetings, who's talks I've seen a dozen times already, is not a great use of everyone's time. Nor does it highlight all of the rich talent in your field from more junior folks and peeps not at "elite" institutions.
January 13, 2025 at 11:00 PM
Reposted by Tim Pullen
Only two more days left to apply! Please help spread the word.
A PhD position in computational genomics is open in our group at Imperial/MRC LMS! 🌟

Join the DANIO-ReCODE Doctoral Network and work on gene regulation, evolution, development, and tissue regeneration. Open to all (except those residing in the UK in the past year). Deadline: 8 Jan 2025. t.ly/fDdDW
Research Assistant with funding to undertake PhD - London (Central), London (Greater) (GB) job with Imperial College London (ICL) | 12834104
About the role: We are seeking an applicant for a fully-funded HORIZON-MSCA-2023-DN Research Assistant position with funding to undertake PhD in th...
www.nature.com
January 6, 2025 at 9:02 PM
Reposted by Tim Pullen
Last few days to apply for a postdoc position in my lab
A postdoctoral position is available in my lab to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: www.imperial.ac.uk/jobs/search-...
January 6, 2025 at 11:05 PM