Thom Hallmark, PhD
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tjhallmark.bsky.social
Thom Hallmark, PhD
@tjhallmark.bsky.social
140 followers 410 following 29 posts
Postdoc studying novel pAgos @WUR Netherlands 🇳🇱
PhD, Biochemistry studying CRISPR-Cas12a2 @USU
BSc, Biochemistry @BYU-idaho
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tjhallmark.bsky.social
Wondered which cleavage substrate Cas12a2 prefers and how it selects between substrates? In this new preprint we find out! A great, continuing collaboration between the Jackson lab at USU and the Beisel Lab at HIRI
www.biorxiv.org/content/10.1...
RNA-triggered CRISPR-Cas12a2 Preferentially and Cooperatively Cleaves Collateral DNA
CRISPR-Cas systems often rely on collateral cleavage activities against nucleic-acid substrates to combat recognized mobile genetic elements. Of the associated RNA-guided Cas effector nucleases, Cas12...
www.biorxiv.org
January 6, 2025 at 9:14 PM
tjhallmark.bsky.social
What a moment! My PhD dissertation is finally finished! 🥳

digitalcommons.usu.edu/etd2023/383/
Mechanisms Regulating Abortive Infection by CRISPR – Cas12a2
In the wake of the 2020 COVID19 pandemic, we have become acutely aware of the threat caused by viral infection. Humans are not alone in being threatened by viruses. Bacteria are under constant attack ...
digitalcommons.usu.edu
December 11, 2024 at 4:13 AM
Reposted by Thom Hallmark, PhD
drjonlim.bsky.social
🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!

Check it out 👇
bioart.niaid.nih.gov
November 23, 2024 at 3:50 PM
tjhallmark.bsky.social
Hello BlueSky! Young scientist looking to connect. Anybody interested in bacterial immunity, structural biology or microscopy?
November 14, 2024 at 1:32 PM