Jon Lim, MRCP PhD
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drjonlim.bsky.social
Jon Lim, MRCP PhD
@drjonlim.bsky.social
Senior Lecturer & Consultant Medical Oncologist in Advanced #Immunotherapy + #CellTherapy at The University of Manchester & The Christie • MANIFEST Deputy Lead • ESMO #TranslationalResearch Faculty Lead

🔗 Bio: bit.ly/Christie_JonLim
(tennis enthusiast 🎾)
Pinned
It's #WorldCancerDay.

So thought it'd be a good idea to update the #StarterPack for #CancerImmunology - our #ImmunoSky #CanSky #OncSky #MedSky #AcademicSky communities are growing 📈 - we are now on Pack 3!

🧑‍🔬 Pack 1
go.bsky.app/Jm8JWdM

🧑‍🔬 Pack 2
go.bsky.app/VCtk6Qd

🧑‍🔬 Pack 3
go.bsky.app/NR7fy4u
Reposted by Jon Lim, MRCP PhD
Excited about not one but 2 fantastic conferences in Manchester! So timely as cell therapies are on the standard care horizon!
...and don’t miss our TIL Summit 2026, taking place the day before (11 Mar 2026), also at the Midland Hotel.

A dedicated forum bringing together UK & international leaders to discuss TIL therapy, manufacturing, biomarkers, and next-generation trials 👇
🚀 Save the Date!

We’re excited to launch our flagship TIL Summit in Manchester: "Unlocking TIL Therapy: A New Era for Melanoma Care in the UK"

🗓 11 March 2026
📍 The Midland Hotel, Manchester
November 30, 2025 at 2:28 PM
⏰ Calling all melanoma enthusiasts!

The abstract submission deadline for the inaugural “Lab to Life: Innovations in Melanoma Research Conference UK 2026” has been extended to 19 December 2025!

Happening 12-13 March 2026 at The Midland Hotel, Manchester.

Submit your abstract and register here:
Home
Lab to Life: Innovations in Melanoma is a UK conference in Manchester on cutting-edge melanoma research, translational science and advances in treatments.
sites.manchester.ac.uk
November 30, 2025 at 2:08 PM
Reposted by Jon Lim, MRCP PhD
🧬 CAR T treatments improve overall survival for patients with large B-cell lymphoma and progression-free survival for patients with multiple myeloma.

Save this Review for your bibliography:
ja.ma/49HHc34
November 29, 2025 at 1:00 PM
🚀 Save the Date!

We’re excited to launch our flagship TIL Summit in Manchester: "Unlocking TIL Therapy: A New Era for Melanoma Care in the UK"

🗓 11 March 2026
📍 The Midland Hotel, Manchester
November 29, 2025 at 11:05 AM
End of an era! @marianapdc.bsky.social is one of the most talented scientists I have ever met; beyond that a super good friend 🙌. So honoured to have overlapped in the lab with you, and see you shine and rise to all the successes you so deserve. Thanks for all the wonderful times.

All the best! 💫
Yesterday marked the end of an almost 7 year era in the @reisesousalab.bsky.social at the @crick.ac.uk 🥹 Feeling immensely grateful to Caetano for his incredible mentorship and guidance, and for fostering the most collaborative and supportive scientific atmosphere in the lab 🌟
November 27, 2025 at 11:18 PM
Reposted by Jon Lim, MRCP PhD
The parents of a three-year-old boy born with a devastating, life-limiting genetic condition say they are now excited for his future after he received a revolutionary stem cell gene therapy treatment developed by researchers at the University of Manchester.
www.bbc.co.uk/news/article...
Hunter syndrome: Boy with rare condition amazes doctors after world-first gene therapy
Oliver has an inherited condition called Hunter syndrome, which causes progressive damage to the body and brain.
www.bbc.co.uk
November 24, 2025 at 11:31 AM
Reposted by Jon Lim, MRCP PhD
Levy on international students’ tuition fees not in best interest of UK, says @duncanivison.bsky.social, president and VC of @manchester.ac.uk
More from @theguardian.com
bit.ly/4r1save
#education #educationnews
Levy on international students’ tuition fees not in best interest of UK, says leader of top university
Duncan Ivison, president of Manchester University, says government’s 6% surcharge plan will ‘hurt the sector’
bit.ly
November 17, 2025 at 12:00 PM
Fantastic opportunity from @turajliclab.bsky.social! 🚀

The CanDy Lab is recruiting an Associate Scientist to drive cutting-edge cancer research across @cruk-mi.bsky.social and @crick.ac.uk.

A rare chance to lead, grow, and shape high-impact science 👇
www.cruk.manchester.ac.uk/career/mi-25...
MI/25/63 Associate Scientist | Cancer Research UK Manchester Institute
We are seeking a highly motivated and accomplished Associate Scientist to help lead and shape the programme. You will act as an operational deputy to Professor Samra Turajlic, helping to bridge activi...
www.cruk.manchester.ac.uk
November 16, 2025 at 5:36 PM
🚨 Save the Date!
Next #ChristieFellows session:

“Preparing a Grant Proposal for PhD or Research Projects”
🎤 Dr Jamie Weaver
🗓️ Tue 18 Nov 2025 | 12:30–13:30
📍 Seminar 4&5, Edu Centre

Learn how to pitch your idea & navigate the grant process from an early-career clinical academic.

#TeamManchester 🐝
November 12, 2025 at 4:55 PM
Reposted by Jon Lim, MRCP PhD
We were proud to see #TeamManchester present at over 10 sessions & 20+ posters at #ESMO2025.

Well done to everyone involved in representing the MCRC on this international stage & demonstrating the commitment of our researchers & clinicians!🐝

See you all in Spain for #ESMO26! 🇪🇸
October 24, 2025 at 9:38 AM
So proud of my colleague Sacha Howell on this latest @nature.com publication reporting on the Breast Cancer-Anti-Progestin Prevention Study 1 (BC-APPS1) - many years in the making: www.nature.com/articles/s41...

Press release from The University of Manchester:
www.manchester.ac.uk/about/news/n...
New study uncovers potential way to prevent breast cancer in pre-menopausal women
A University of Manchester study funded by Breast Cancer Now and supported by Prevent Breast Cancer, reveals a drug approved for use in other conditions could be repurposed to prevent breast cancer in...
www.manchester.ac.uk
November 6, 2025 at 10:04 AM
Reposted by Jon Lim, MRCP PhD
#ESMO25: Positive efficacy results without safety concerns seen with NW-301V, a TCR-T therapy targeting KRAS G12V, in patients with KRAS G12V-mutant advanced #GICancer in a phase I #ClinicalTrial.
#ESMODailyReporter🔗 https://ow.ly/jouK50XjATp


Jon Lim, MRCP PhD
October 30, 2025 at 4:30 PM
Reposted by Jon Lim, MRCP PhD
We joined forces across Europe to map, connect & accelerate the development of ATMPs — gene, cell and tissue-based therapies that could transform patient care.

We make ATMP innovation faster, safer and more accessible for everyone.

👉 join4atmp.eu

#JOIN4ATMP #ATMP #HorizonEurope #HealthInnovation
October 24, 2025 at 10:13 AM
Reposted by Jon Lim, MRCP PhD
There’s still time to sign up for our Taster Session on Thursday 30 October to learn more about studying a #PhD in Cancer Sciences.

⏰ Learn about our application process
🧑‍ Hear from current students
🐝 Learn what it’s like to study in Manchester

www.eventbrite.co.uk/e/cruk-mcrc-...
CRUK MCRC PhD Taster Session 2025–2026 : Discover, Apply, Lead
From Curiosity to Cure: Explore PhD Opportunities at CRUK MCRC, Meet the Researchers and Map Your Future
www.eventbrite.co.uk
October 27, 2025 at 9:56 AM
Reposted by Jon Lim, MRCP PhD
Our fourth and final day of #ESMO25! We listened to talks by Consultant & Fellow Alum Melissa Frizziero and Honorary Academic Consultant & Fellowships Specialty Lead for Medical Oncology @drjonlim.bsky.social! We also learned about the various professional development opportunities offered by ESMO 🎓
October 20, 2025 at 2:36 PM
Reposted by Jon Lim, MRCP PhD
#ESMO25 Day 3 has been a huge success, with talks from a number of our Fellow Supervisors, including Dr Andrew Clamp presenting original research on the ICON8B trial. We also caught up with some of our current and previous fellows who have been presenting posters at the conference! 📊
October 19, 2025 at 2:41 PM
Reposted by Jon Lim, MRCP PhD
Day 2 of #ESMO25 has been fantastic with many Christie speakers.
✨ Highlights include Prof. Corrine Faivre-Finn, Dr Mairead McNamara & Prof. Samra Turajlić. We were also delighted to see Gemma Jones, The Christie’s Lead Nurse for SACT, presenting on eProms in streamlining pre-treatment assessment.
October 18, 2025 at 4:40 PM
Reposted by Jon Lim, MRCP PhD
On Day 1 of #ESMO25 we heard from Prof Fiona Thistlethwaite and Dr Matthew Krebs discussing developmental therapeutics. Over 35,000 delegates will be in attendance at the conference this year - we are delighted to be part of such a fantastic community 👏
October 17, 2025 at 3:49 PM
🗞️ Check out my short #ESMODailyReporter editorial on early data from a first-in-human TCR-T therapy targeting KRAS G12V in advanced pancreatic & colorectal cancer, presented today by Dr Bai from Zhejiang University.

#ESMO25
#CellTherapy
#ESMOAmbassadors
@myesmo.bsky.social
First-in-human trial of a TCR-T therapy targeting KRAS G12V reports a significant response rate
Preliminary results of NW-301V are promising, with a lack of severe adverse effects at all doses tested in patients with pancreatic cancer or colorectal cancer
dailyreporter.esmo.org
October 20, 2025 at 8:08 PM
Reposted by Jon Lim, MRCP PhD
Friday we celebrated our new MRC Centre of Research Excellence in Exposome Immunology: a joint venture with Oxford that we call MOXIE (Manchester-Oxford Immunology of the Exposome). This challenging adventure is off to a great start. @exposomeimmunology.bsky.social
October 20, 2025 at 1:09 PM
Reposted by Jon Lim, MRCP PhD
#ESMOAmbassadors: for the second year bringing you the life that is happening at #ESMO25.

✨ A heartfelt thank you to the #ESMOAmbassadors for their reporting on the latest in #CancerResearch & practice. Stay tuned!

#ONEoncologycommunity
Delighted to be part of the #ESMOAmbassadors team at #ESMO25! 🌍

Let’s connect and discuss the latest news here in Berlin >>> and beyond!

#ONEOncologyCommunity
@myesmo.bsky.social
October 19, 2025 at 12:46 PM
Delighted to be part of the #ESMOAmbassadors team at #ESMO25! 🌍

Let’s connect and discuss the latest news here in Berlin >>> and beyond!

#ONEOncologyCommunity
@myesmo.bsky.social
October 19, 2025 at 10:20 AM
🌟 Tour de force proffered paper by Dr Charlotte Spencer, Histopathology SpR + recent PhD Fellow in @turajliclab.bsky.social @crick.ac.uk

Huge congrats on the ESMO Merit Award 🎉 So well deserved — proud of you, my friend! 💫

#ESMO25 #TranslationalResearch #TRACERxRenal
October 18, 2025 at 8:49 AM
💥 Is it prime time for adoptive cell therapy in solid tumours?

📚 Special Educational Session on the state-of-the-art and future of cell therapies - evolving fast from promise to practice.

👀 Watch this space…

#ESMO25 #ESMOAmbassadors #CellTherapy #Immunotherapy
October 18, 2025 at 7:49 AM
Strong representation from our Experimental Cancer Medicines Team (ECMT) at The Christie, led by Dr Matthew Krebs at #ESMO25.

Mini-oral presentation re: global phase 1 data on divarasib (GDC-6036) - a next-gen KRAS G12C inhibitor with promising activity.

#TeamManchester 🐝
@mcrcnews.bsky.social
October 17, 2025 at 3:24 PM