Christian Tidona
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tidona.bsky.social
Christian Tidona
@tidona.bsky.social
Incurably Curious | Scientist Entrepreneur | Founder and Managing Director of BioMed X | Follow me for news and views about #aging, #oncology, #immunology, #neuroscience, #artificialintelligence, #innovation, #entrepreneurship, and #leadership.
Reposted by Christian Tidona
This is wild - reading protein sequence information into DNA via Edman degradation and barcoding of each amino acid www.biorxiv.org/content/10.1...
#lifescience
Peptide sequencing via reverse translation of peptides into DNA
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
June 4, 2024 at 8:36 AM
On my way to #JPM2024 week in San Francisco. Looking forward to reconnecting with old friends and partners, and meeting new ones!

Please send me a direct message in case you are interested in learning how our BioMed X Institutes in New Haven and Heidelberg solve big biomedical R&D challenges.
January 6, 2024 at 10:35 AM
Here is a very nice post by Andrii Buvailo about the 11 #biopharma #trends to watch in 2024: www.techlifesci.com/p/11-biophar...

Among them:
✅ Organoid intelligence
✅ AI in drug discovery and clinical research
✅ Genome editing
✅ RNA modalities and their delivery

#artificialintelligence
January 3, 2024 at 12:38 PM
As 2023 comes to an end, please enjoy Nature’s picks of the best #science #images of this year: www.nature.com/immersive/d4...

The example below shows the result of a multicellularity long-term #evolution experiment with snowflake yeast.

#HappyNewYear #beautifulscience #microbiology
December 31, 2023 at 7:26 AM
Check out this interesting Nature Electronics article in which researchers at the lab of Feng Guo have combined lab-grown 3D human #brain #organoids with electronic hardware to perform speech recognition and nonlinear equation prediction tasks: www.nature.com/articles/s41...

#artificialintelligence
December 18, 2023 at 11:57 AM
Check out this fascinating article in Nature in which the authors analyzed 20M research articles and 4M patent applications. They found clear evidence that despite a trend towards remote collaboration, in-person teams are generally more likely to produce breakthroughs: www.nature.com/articles/s41...
December 17, 2023 at 3:59 PM
What if we could visualize the spatial distributions of T cell clonotypes in tumor tissues together with their effects on adjacent tumor and immune cells?
Here is Slide-TCR-seq, a new method for spatial mapping of TCRs and transcriptomes in tissue sections: www.sciencedirect.com/science/arti...
December 12, 2023 at 10:52 AM
Did you know that #brain-resident regulatory T cells play an important role in #neuroprotection and tissue #repair?
Check out this very interesting review article in Nature Reviews #Immunology by Adrian Liston et al.: www.nature.com/articles/s41...

#neuroinflammation #neurodegeneration #psychiatric
December 6, 2023 at 6:33 AM
Did you know that the 1st molecular glue was discovered more than 40 years ago?
Check out this fascinating article in Cell by Stuart Schreiber about the rise of molecular glues that started with the surprising discovery of the immunosuppressive activity of cyclosporin A: www.cell.com/cell/fulltex...
December 5, 2023 at 10:33 AM
"We have not inherited the world from our parents. We have borrowed it from our children."

Image: #DALLE3

#COP28 #sustainability #climatecrisis
December 2, 2023 at 9:14 AM
Great cartoon by #Gapingvoid summarizing our mission at BioMed X:

By building local #innovation ecosystems with high density and #diversity of #talent and a #culture that fosters cross-pollination, we are "amplifying the stuff that matters".

Interested in joining us? Register here: career.bio.mx
December 2, 2023 at 8:55 AM
Did you know that on average, every single somatic cell in our body acquires 20 to 30 random #mutations per year? This phenomenon is called #aging. As we age, our #tissues become a mosaic of #cells with increasing #genomic #diversity. Read more: www.frontiersin.org/articles/10....
November 29, 2023 at 1:30 PM
Before you post, let your words pass through 3 gates:

Is it true?
Is it necessary?
Is it kind?

Happy to be on #Bluesky.

#buddhist #wisdom #leadership
November 28, 2023 at 9:08 AM