Thomas Andrillon
@thomasandrillon.bsky.social
Studying the stream of consciousness during sleep and wakefulness
Neuroscientist at the Paris Brain Institute
Chargé de Recherche Inserm
Adjunct Senior Research Fellow at Monash University
Co-Editor-in-Chief of Neuroscience of Consciousness (OUP)
Neuroscientist at the Paris Brain Institute
Chargé de Recherche Inserm
Adjunct Senior Research Fellow at Monash University
Co-Editor-in-Chief of Neuroscience of Consciousness (OUP)
Reposted by Thomas Andrillon
Sleep supports brain health partly by regulating fluid dynamics to clear waste. @ulvlarsen.bsky.social &co probe the relation between #sleep & fluid movement in the human #brain, finding that #SleepPressure & intensity have distinct effects on brain pulsations @plosbiology.org 🧪 plos.io/3XQWCL6
November 25, 2025 at 5:40 PM
Sleep supports brain health partly by regulating fluid dynamics to clear waste. @ulvlarsen.bsky.social &co probe the relation between #sleep & fluid movement in the human #brain, finding that #SleepPressure & intensity have distinct effects on brain pulsations @plosbiology.org 🧪 plos.io/3XQWCL6
Reposted by Thomas Andrillon
🚨Friends, we’re happy to share that our book is available for pre-order! 🎉
We aimed to cover all the foundations of the topic in an accessible manner for a large audience.
It could help set up a bachelor-level curriculum on the topic.
Pre-orders are very key for the fate of books: shorturl.at/Dxbif
We aimed to cover all the foundations of the topic in an accessible manner for a large audience.
It could help set up a bachelor-level curriculum on the topic.
Pre-orders are very key for the fate of books: shorturl.at/Dxbif
November 26, 2025 at 11:38 AM
🚨Friends, we’re happy to share that our book is available for pre-order! 🎉
We aimed to cover all the foundations of the topic in an accessible manner for a large audience.
It could help set up a bachelor-level curriculum on the topic.
Pre-orders are very key for the fate of books: shorturl.at/Dxbif
We aimed to cover all the foundations of the topic in an accessible manner for a large audience.
It could help set up a bachelor-level curriculum on the topic.
Pre-orders are very key for the fate of books: shorturl.at/Dxbif
Out now in @commsbio.nature.com!
We studied brain-heart interactions during mind wandering and mind blanking.
Mind blanking is associated with a greater heart/brain decoupling, complicating the idea of an attentional switch between external & internal environments!
🧠🔄🫀🧪
We studied brain-heart interactions during mind wandering and mind blanking.
Mind blanking is associated with a greater heart/brain decoupling, complicating the idea of an attentional switch between external & internal environments!
🧠🔄🫀🧪
Multimodal analysis of spontaneous attentional state dynamics during sustained task performance reveals distinctive profiles of brain-heart interaction in mind-wandering and mind-blanking.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
When your heart isn’t in it anymore: cardiac correlates of task disengagement - Communications Biology
Multimodal analysis of spontaneous attentional state dynamics during sustained task performance reveals distinctive profiles of brain–heart interaction in mind-wandering and mind-blanking.
www.nature.com
November 25, 2025 at 10:01 AM
Out now in @commsbio.nature.com!
We studied brain-heart interactions during mind wandering and mind blanking.
Mind blanking is associated with a greater heart/brain decoupling, complicating the idea of an attentional switch between external & internal environments!
🧠🔄🫀🧪
We studied brain-heart interactions during mind wandering and mind blanking.
Mind blanking is associated with a greater heart/brain decoupling, complicating the idea of an attentional switch between external & internal environments!
🧠🔄🫀🧪
Reposted by Thomas Andrillon
Multimodal analysis of spontaneous attentional state dynamics during sustained task performance reveals distinctive profiles of brain-heart interaction in mind-wandering and mind-blanking.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
When your heart isn’t in it anymore: cardiac correlates of task disengagement - Communications Biology
Multimodal analysis of spontaneous attentional state dynamics during sustained task performance reveals distinctive profiles of brain–heart interaction in mind-wandering and mind-blanking.
www.nature.com
November 24, 2025 at 6:38 PM
Multimodal analysis of spontaneous attentional state dynamics during sustained task performance reveals distinctive profiles of brain-heart interaction in mind-wandering and mind-blanking.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Thomas Andrillon
" #Ketamine disrupts #consciousness in healthy participants in relation with #psychotic-like symptoms"
🥸 This is the title of our last preprint @biorxiv-neursci.bsky.social giving some insights on how ketamine at subanesthetic doses mimicks psychosis symptoms!
www.biorxiv.org/content/10.1...
🥸 This is the title of our last preprint @biorxiv-neursci.bsky.social giving some insights on how ketamine at subanesthetic doses mimicks psychosis symptoms!
www.biorxiv.org/content/10.1...
Ketamine disrupts consciousness in healthy participants in relation with psychotic-like symptoms
Ketamine is an NMDA-receptor antagonist, which alters the state of wakeful consciousness at high doses. At lower doses, it induces reversible psychotic-like symptoms and has been used as a pharmacolog...
www.biorxiv.org
November 13, 2025 at 7:18 PM
" #Ketamine disrupts #consciousness in healthy participants in relation with #psychotic-like symptoms"
🥸 This is the title of our last preprint @biorxiv-neursci.bsky.social giving some insights on how ketamine at subanesthetic doses mimicks psychosis symptoms!
www.biorxiv.org/content/10.1...
🥸 This is the title of our last preprint @biorxiv-neursci.bsky.social giving some insights on how ketamine at subanesthetic doses mimicks psychosis symptoms!
www.biorxiv.org/content/10.1...
It should of course read "schizophrenia"! Oopsie...
Is #ketamine a good pharmacological model of #schyzophrenia?
W/ @lucieberko.bsky.social, @standehaene.bsky.social, R Gaillard, and A Salvador, we investigated the impact of ketamine on conscious processing and attention in healthy subjects.
Check the preprint!
www.biorxiv.org/content/10.1...
🧠🧪
W/ @lucieberko.bsky.social, @standehaene.bsky.social, R Gaillard, and A Salvador, we investigated the impact of ketamine on conscious processing and attention in healthy subjects.
Check the preprint!
www.biorxiv.org/content/10.1...
🧠🧪
November 13, 2025 at 1:43 PM
It should of course read "schizophrenia"! Oopsie...
Is #ketamine a good pharmacological model of #schyzophrenia?
W/ @lucieberko.bsky.social, @standehaene.bsky.social, R Gaillard, and A Salvador, we investigated the impact of ketamine on conscious processing and attention in healthy subjects.
Check the preprint!
www.biorxiv.org/content/10.1...
🧠🧪
W/ @lucieberko.bsky.social, @standehaene.bsky.social, R Gaillard, and A Salvador, we investigated the impact of ketamine on conscious processing and attention in healthy subjects.
Check the preprint!
www.biorxiv.org/content/10.1...
🧠🧪
November 13, 2025 at 1:03 PM
Is #ketamine a good pharmacological model of #schyzophrenia?
W/ @lucieberko.bsky.social, @standehaene.bsky.social, R Gaillard, and A Salvador, we investigated the impact of ketamine on conscious processing and attention in healthy subjects.
Check the preprint!
www.biorxiv.org/content/10.1...
🧠🧪
W/ @lucieberko.bsky.social, @standehaene.bsky.social, R Gaillard, and A Salvador, we investigated the impact of ketamine on conscious processing and attention in healthy subjects.
Check the preprint!
www.biorxiv.org/content/10.1...
🧠🧪
Reposted by Thomas Andrillon
How do internal bodily rhythms influence #brain activity & motor function? @tahnee-engelen.bsky.social &co show that #cardiac, #respiratory & #gastric rhythms independently modulate motor excitability, revealing distinct #interoceptive profiles across individuals @plosbiology.org 🧪 plos.io/4nMtpLT
November 13, 2025 at 10:17 AM
How do internal bodily rhythms influence #brain activity & motor function? @tahnee-engelen.bsky.social &co show that #cardiac, #respiratory & #gastric rhythms independently modulate motor excitability, revealing distinct #interoceptive profiles across individuals @plosbiology.org 🧪 plos.io/4nMtpLT
Reposted by Thomas Andrillon
Attentional failures during wakefulness after sleep deprivation are tightly orchestrated in a series of brain–body changes, including neuronal shifts, pupil constriction and cerebrospinal fluid (CSF) flow pulsations
@lauradata.bsky.social @ziy027.bsky.social
www.nature.com/articles/s41...
@lauradata.bsky.social @ziy027.bsky.social
www.nature.com/articles/s41...
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics - Nature Neuroscience
Yang et al. show that moments of failed attention we experience after sleep deprivation reflect brief ‘sleep-like’ episodes in the brain, corresponding to a brain- and body-wide event with altered bra...
www.nature.com
November 12, 2025 at 8:18 PM
Attentional failures during wakefulness after sleep deprivation are tightly orchestrated in a series of brain–body changes, including neuronal shifts, pupil constriction and cerebrospinal fluid (CSF) flow pulsations
@lauradata.bsky.social @ziy027.bsky.social
www.nature.com/articles/s41...
@lauradata.bsky.social @ziy027.bsky.social
www.nature.com/articles/s41...
Reposted by Thomas Andrillon
hot take: none of the major theories of consciousness (HOT, RPT, GNWT etc.) is "computational" so the current buzz around "computational functionalism" is getting progressively surreal. None of these th. claims that there is an algorith that will take you from unconscious contents to conscious ones.
November 12, 2025 at 8:52 AM
hot take: none of the major theories of consciousness (HOT, RPT, GNWT etc.) is "computational" so the current buzz around "computational functionalism" is getting progressively surreal. None of these th. claims that there is an algorith that will take you from unconscious contents to conscious ones.
Has anyone else gotten emails from bgpt.pro? 🤔
It seems to be an LLM that analyzed a review I co-authored (on spontaneous thoughts in disorders of consciousness) and contacted the corresponding author to propose a pipeline addressing our open questions.
This is so spooky!
It seems to be an LLM that analyzed a review I co-authored (on spontaneous thoughts in disorders of consciousness) and contacted the corresponding author to propose a pipeline addressing our open questions.
This is so spooky!
Solve any biology problem with citations + insights + visualizations
bgpt.pro
November 11, 2025 at 2:30 PM
Has anyone else gotten emails from bgpt.pro? 🤔
It seems to be an LLM that analyzed a review I co-authored (on spontaneous thoughts in disorders of consciousness) and contacted the corresponding author to propose a pipeline addressing our open questions.
This is so spooky!
It seems to be an LLM that analyzed a review I co-authored (on spontaneous thoughts in disorders of consciousness) and contacted the corresponding author to propose a pipeline addressing our open questions.
This is so spooky!
Reposted by Thomas Andrillon
A brain injury was reported in a trial using ultrasound, framed as low-intensity TUS. Kim Butts Pauly and I reviewed the case and disagreed with how it's presented. Key acoustic data are missing.
Case: doi.org/10.1016/j.br...
Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...
Case: doi.org/10.1016/j.br...
Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...
Brain Injury During Focused Ultrasound Neuromodulation for Substance Use Disorder
www.sciencedirect.com
November 3, 2025 at 11:39 AM
A brain injury was reported in a trial using ultrasound, framed as low-intensity TUS. Kim Butts Pauly and I reviewed the case and disagreed with how it's presented. Key acoustic data are missing.
Case: doi.org/10.1016/j.br...
Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...
Case: doi.org/10.1016/j.br...
Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...
Reposted by Thomas Andrillon
This was a fabulous, once in a lifetime colloquium -- and now the videos are available in high quality on the College de France web site @college-de-france.fr
www.college-de-france.fr/fr/agenda/co...
With talks by Edvard Moser, Nancy Kanwisher, Liz Spelke, Manuela Piazza, Luca Bonatti and more!
www.college-de-france.fr/fr/agenda/co...
With talks by Edvard Moser, Nancy Kanwisher, Liz Spelke, Manuela Piazza, Luca Bonatti and more!
November 2, 2025 at 3:08 PM
This was a fabulous, once in a lifetime colloquium -- and now the videos are available in high quality on the College de France web site @college-de-france.fr
www.college-de-france.fr/fr/agenda/co...
With talks by Edvard Moser, Nancy Kanwisher, Liz Spelke, Manuela Piazza, Luca Bonatti and more!
www.college-de-france.fr/fr/agenda/co...
With talks by Edvard Moser, Nancy Kanwisher, Liz Spelke, Manuela Piazza, Luca Bonatti and more!
Reposted by Thomas Andrillon
For @us.theguardian.com I wrote about "paradoxical insomnia"—the strange experience of being asleep but not *knowing* you're asleep
Thanks to @theguardian.com for this spotlight on "paradoxical insomnia".
One of the many fascinating oddities of sleep, when people look like they slept, but do not feel like they slept.
#sleep #insomnia
🧠🧪💤
www.theguardian.com/wellness/202...
One of the many fascinating oddities of sleep, when people look like they slept, but do not feel like they slept.
#sleep #insomnia
🧠🧪💤
www.theguardian.com/wellness/202...
You were asleep but swear you weren’t: what is paradoxical insomnia?
We don’t always know when we’re asleep or awake. This can affect how rested we feel
www.theguardian.com
November 3, 2025 at 5:43 PM
For @us.theguardian.com I wrote about "paradoxical insomnia"—the strange experience of being asleep but not *knowing* you're asleep
Thanks to @theguardian.com for this spotlight on "paradoxical insomnia".
One of the many fascinating oddities of sleep, when people look like they slept, but do not feel like they slept.
#sleep #insomnia
🧠🧪💤
www.theguardian.com/wellness/202...
One of the many fascinating oddities of sleep, when people look like they slept, but do not feel like they slept.
#sleep #insomnia
🧠🧪💤
www.theguardian.com/wellness/202...
You were asleep but swear you weren’t: what is paradoxical insomnia?
We don’t always know when we’re asleep or awake. This can affect how rested we feel
www.theguardian.com
October 31, 2025 at 2:25 PM
Thanks to @theguardian.com for this spotlight on "paradoxical insomnia".
One of the many fascinating oddities of sleep, when people look like they slept, but do not feel like they slept.
#sleep #insomnia
🧠🧪💤
www.theguardian.com/wellness/202...
One of the many fascinating oddities of sleep, when people look like they slept, but do not feel like they slept.
#sleep #insomnia
🧠🧪💤
www.theguardian.com/wellness/202...
Reposted by Thomas Andrillon
#Hemispherotomy is a surgical treatment for #epilepsy by disconnecting a portion of the #cortex. Michele Colombo, Jacopo Favaro, @anilseth.bsky.social, Marcello Massimini &co show that the isolated cortex has #EEG patterns resembling deep #sleep or #anesthesia @plosbiology.org 🧪 plos.io/3J9ci8X
October 17, 2025 at 4:33 PM
#Hemispherotomy is a surgical treatment for #epilepsy by disconnecting a portion of the #cortex. Michele Colombo, Jacopo Favaro, @anilseth.bsky.social, Marcello Massimini &co show that the isolated cortex has #EEG patterns resembling deep #sleep or #anesthesia @plosbiology.org 🧪 plos.io/3J9ci8X
Reposted by Thomas Andrillon
Please RT! 🙏🙏🙏
1/3 How do you correct for multiple comparisons? Do you take into account *all* comparisons that can render the paper publishable? Most of us don’t. In this NHB piece, Yoav Benjamini, Yoav Zeevi and I argue that it’s time to change our practices >>
www.nature.com/articles/s41...
1/3 How do you correct for multiple comparisons? Do you take into account *all* comparisons that can render the paper publishable? Most of us don’t. In this NHB piece, Yoav Benjamini, Yoav Zeevi and I argue that it’s time to change our practices >>
www.nature.com/articles/s41...
Correction for multiple comparisons should be ubiquitous - Nature Human Behaviour
Nature Human Behaviour - Correction for multiple comparisons should be ubiquitous
www.nature.com
October 16, 2025 at 5:28 PM
Please RT! 🙏🙏🙏
1/3 How do you correct for multiple comparisons? Do you take into account *all* comparisons that can render the paper publishable? Most of us don’t. In this NHB piece, Yoav Benjamini, Yoav Zeevi and I argue that it’s time to change our practices >>
www.nature.com/articles/s41...
1/3 How do you correct for multiple comparisons? Do you take into account *all* comparisons that can render the paper publishable? Most of us don’t. In this NHB piece, Yoav Benjamini, Yoav Zeevi and I argue that it’s time to change our practices >>
www.nature.com/articles/s41...
Reposted by Thomas Andrillon
1/ "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans" - out now in @plosbiology.org, led by Michele Colombo, Jacopo Favaro, & Marcello Massimini. 🧠
October 17, 2025 at 7:57 AM
1/ "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans" - out now in @plosbiology.org, led by Michele Colombo, Jacopo Favaro, & Marcello Massimini. 🧠
Reposted by Thomas Andrillon
When I was an undergrad, I saw a talk by Oliver Sacks about music. During the Q&A, someone asked Sacks if he thought science would reveal the deepest mysteries of art. Sacks (a rare humanist among scientists) said that he doubted it, at which Eric Kandel (the host) leaped up and grabbed the mic.
October 15, 2025 at 9:27 AM
When I was an undergrad, I saw a talk by Oliver Sacks about music. During the Q&A, someone asked Sacks if he thought science would reveal the deepest mysteries of art. Sacks (a rare humanist among scientists) said that he doubted it, at which Eric Kandel (the host) leaped up and grabbed the mic.
Check out our new preprint:
www.biorxiv.org/content/10.1...
And Paris' thread (@parboulakis.bsky.social):
bsky.app/profile/parb...
Where we explore the neural signature of mind blanking using EEG and fMRI combined!
www.biorxiv.org/content/10.1...
And Paris' thread (@parboulakis.bsky.social):
bsky.app/profile/parb...
Where we explore the neural signature of mind blanking using EEG and fMRI combined!
October 16, 2025 at 12:16 PM
Check out our new preprint:
www.biorxiv.org/content/10.1...
And Paris' thread (@parboulakis.bsky.social):
bsky.app/profile/parb...
Where we explore the neural signature of mind blanking using EEG and fMRI combined!
www.biorxiv.org/content/10.1...
And Paris' thread (@parboulakis.bsky.social):
bsky.app/profile/parb...
Where we explore the neural signature of mind blanking using EEG and fMRI combined!
Reposted by Thomas Andrillon
In the line of good news, our lab's magician @parboulakis.bsky.social is presenting our latest work with @thomasandrillon.bsky.social @anikokusztor.bsky.social and #TsuchiyaNao. We combined fMRI and EEG & found that #MindBlanking has different neural signatures depending on perceived vigilance 😍. 🧵👇
🚨Preprint alert 🚨. Our work “Distinct cortical profiles underlie the common reportability of thought-free experiences” is available at www.biorxiv.org/content/10.1.... 🧵A thread ...
Distinct cortical profiles underlie the common reportability of thought-free experiences
Mind blanking (MB) is a mental state of seemingly no reportable thought content. The question of how we can entertain no thoughts while awake is challenging for the study of spontaneous thinking. By c...
www.biorxiv.org
October 16, 2025 at 12:14 PM
In the line of good news, our lab's magician @parboulakis.bsky.social is presenting our latest work with @thomasandrillon.bsky.social @anikokusztor.bsky.social and #TsuchiyaNao. We combined fMRI and EEG & found that #MindBlanking has different neural signatures depending on perceived vigilance 😍. 🧵👇
Reposted by Thomas Andrillon
🚨Preprint alert 🚨. Our work “Distinct cortical profiles underlie the common reportability of thought-free experiences” is available at www.biorxiv.org/content/10.1.... 🧵A thread ...
Distinct cortical profiles underlie the common reportability of thought-free experiences
Mind blanking (MB) is a mental state of seemingly no reportable thought content. The question of how we can entertain no thoughts while awake is challenging for the study of spontaneous thinking. By c...
www.biorxiv.org
October 16, 2025 at 12:00 PM
🚨Preprint alert 🚨. Our work “Distinct cortical profiles underlie the common reportability of thought-free experiences” is available at www.biorxiv.org/content/10.1.... 🧵A thread ...
I was once told: "never try EEG+fMRI!"
It was sound advice... but we did it anyway!
Thrilled to share our first preprint, where we explore the neural signatures of mind blanking, linking the sleep-like slow waves seen in #EEG to patterns of hyperconnectivity in #fMRI.
🧠🧪💤
It was sound advice... but we did it anyway!
Thrilled to share our first preprint, where we explore the neural signatures of mind blanking, linking the sleep-like slow waves seen in #EEG to patterns of hyperconnectivity in #fMRI.
🧠🧪💤
🚨Preprint alert 🚨. Our work “Distinct cortical profiles underlie the common reportability of thought-free experiences” is available at www.biorxiv.org/content/10.1.... 🧵A thread ...
Distinct cortical profiles underlie the common reportability of thought-free experiences
Mind blanking (MB) is a mental state of seemingly no reportable thought content. The question of how we can entertain no thoughts while awake is challenging for the study of spontaneous thinking. By c...
www.biorxiv.org
October 16, 2025 at 12:13 PM
Reposted by Thomas Andrillon
Age and gender distortion in online media and large language models
"Furthermore, when generating and evaluating resumes, ChatGPT assumes that women are younger and less experienced, rating older male applicants as of higher quality."
No surprise, but now documented:
www.nature.com/articles/s41...
"Furthermore, when generating and evaluating resumes, ChatGPT assumes that women are younger and less experienced, rating older male applicants as of higher quality."
No surprise, but now documented:
www.nature.com/articles/s41...
Age and gender distortion in online media and large language models - Nature
Stereotypes of age-related gender bias are socially distorted, as evidenced by the age gap in the representations of women and men across various media and algorithms, despite no systematic age differ...
www.nature.com
October 16, 2025 at 8:53 AM
Age and gender distortion in online media and large language models
"Furthermore, when generating and evaluating resumes, ChatGPT assumes that women are younger and less experienced, rating older male applicants as of higher quality."
No surprise, but now documented:
www.nature.com/articles/s41...
"Furthermore, when generating and evaluating resumes, ChatGPT assumes that women are younger and less experienced, rating older male applicants as of higher quality."
No surprise, but now documented:
www.nature.com/articles/s41...
Sleep is still a bit of a mystery! Beautiful article from @vyazovskiy.bsky.social!
aeon.co/essays/two-b...
aeon.co/essays/two-b...
Two billion humans are doing something bizarre right now: sleeping | Aeon Essays
It is our biggest blind spot, a bizarre experience that befalls us every day, and can’t be explained by our need for rest
aeon.co
October 16, 2025 at 7:49 AM
Sleep is still a bit of a mystery! Beautiful article from @vyazovskiy.bsky.social!
aeon.co/essays/two-b...
aeon.co/essays/two-b...