Wai-Hong Tham
@thamlab.bsky.social
🇲🇾 scientist in 🇦🇺 | 🦟 🩸 #malaria |🦙 #nanobodies | Prof @WEHI_research @ourANU | on Wurundjeri, Ngunnawal & Ngambri lands | views my own 🏃🏻♀️ 🍜
Reposted by Wai-Hong Tham
Next up: David Vaux with "An Office for Research Integrity in Australia – What are the barriers?"
* 23 European countries and 6 others have offices for research integrity.
* Australia has a guide with principles and responsibilities but institutions essentially investigate themselves.
#IRICSydney
* 23 European countries and 6 others have offices for research integrity.
* Australia has a guide with principles and responsibilities but institutions essentially investigate themselves.
#IRICSydney
November 17, 2025 at 3:34 AM
Next up: David Vaux with "An Office for Research Integrity in Australia – What are the barriers?"
* 23 European countries and 6 others have offices for research integrity.
* Australia has a guide with principles and responsibilities but institutions essentially investigate themselves.
#IRICSydney
* 23 European countries and 6 others have offices for research integrity.
* Australia has a guide with principles and responsibilities but institutions essentially investigate themselves.
#IRICSydney
Introducing Dr Jaison D Sa @jaisondsa.bsky.social who was awarded his PhD from University of Melbourne 🎉🎉
Co-supervised by Phillip Pymm and me
🩸Stabilized vivax antigen for serodiagnostics
🧬 Alpseq open source nanobody discovery workflow
🦙Nanobodies to Plasmodium adhesins – watch this space!
Co-supervised by Phillip Pymm and me
🩸Stabilized vivax antigen for serodiagnostics
🧬 Alpseq open source nanobody discovery workflow
🦙Nanobodies to Plasmodium adhesins – watch this space!
November 13, 2025 at 1:10 AM
Introducing Dr Jaison D Sa @jaisondsa.bsky.social who was awarded his PhD from University of Melbourne 🎉🎉
Co-supervised by Phillip Pymm and me
🩸Stabilized vivax antigen for serodiagnostics
🧬 Alpseq open source nanobody discovery workflow
🦙Nanobodies to Plasmodium adhesins – watch this space!
Co-supervised by Phillip Pymm and me
🩸Stabilized vivax antigen for serodiagnostics
🧬 Alpseq open source nanobody discovery workflow
🦙Nanobodies to Plasmodium adhesins – watch this space!
Reposted by Wai-Hong Tham
The ostriches have been culled and that particular H5N1 outbreak has finally been contained.
Here is @brandyzadrozny.bsky.social's reliably excellent account of the entire ordeal.
www.msnbc.com/news/news-an...
Here is @brandyzadrozny.bsky.social's reliably excellent account of the entire ordeal.
www.msnbc.com/news/news-an...
Why the conspiratorial right rallied around a flock of ostriches
The anti-vaccine, anti-government crusade to save "the miracle cure birds" is over — and the fringe activists lost.
www.msnbc.com
November 8, 2025 at 12:17 AM
The ostriches have been culled and that particular H5N1 outbreak has finally been contained.
Here is @brandyzadrozny.bsky.social's reliably excellent account of the entire ordeal.
www.msnbc.com/news/news-an...
Here is @brandyzadrozny.bsky.social's reliably excellent account of the entire ordeal.
www.msnbc.com/news/news-an...
Reposted by Wai-Hong Tham
1/New paper from Zheng Wu, Phong Nguyen et al. @cri-utsw.bsky.social shows how cells balance the two pathways that produce purine nucleotides: de novo purine biosynthesis (DNPB) and purine salvage. The surprising mechanism involves NUDT5, a Nudix hydrolase
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT
Cells generate purine nucleotides through de novo purine biosynthesis (DNPB) and purine salvage. Purine salvage represses DNPB to prevent excessive purine nucleotide synthesis through mechanisms that ...
www.science.org
November 6, 2025 at 7:01 PM
1/New paper from Zheng Wu, Phong Nguyen et al. @cri-utsw.bsky.social shows how cells balance the two pathways that produce purine nucleotides: de novo purine biosynthesis (DNPB) and purine salvage. The surprising mechanism involves NUDT5, a Nudix hydrolase
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Wai-Hong Tham
We’re delighted to share our most recent quarterly report from Altmetric Explorer to showcase the top 5 trending articles from across our publications, ranked by Altmetric score. See the thread below for trending articles and find out more here: buff.ly/rcMJA2N
November 7, 2025 at 4:43 PM
We’re delighted to share our most recent quarterly report from Altmetric Explorer to showcase the top 5 trending articles from across our publications, ranked by Altmetric score. See the thread below for trending articles and find out more here: buff.ly/rcMJA2N
Reposted by Wai-Hong Tham
#ARCschedule Nov25
Outcomes expected for DECRA, LIEF & presumably(?) Centres of Excellence ("postponed" on 3 Nov).
Other events:
🔹Open: Discovery Projects EOI
🔹Close: ITRP & Future Fellowships
🔹Selection meeting: Linkage Projects (2025 round 2)
Data ▶️ docs.google.com/spreadsheets...
Outcomes expected for DECRA, LIEF & presumably(?) Centres of Excellence ("postponed" on 3 Nov).
Other events:
🔹Open: Discovery Projects EOI
🔹Close: ITRP & Future Fellowships
🔹Selection meeting: Linkage Projects (2025 round 2)
Data ▶️ docs.google.com/spreadsheets...
November 4, 2025 at 11:39 PM
#ARCschedule Nov25
Outcomes expected for DECRA, LIEF & presumably(?) Centres of Excellence ("postponed" on 3 Nov).
Other events:
🔹Open: Discovery Projects EOI
🔹Close: ITRP & Future Fellowships
🔹Selection meeting: Linkage Projects (2025 round 2)
Data ▶️ docs.google.com/spreadsheets...
Outcomes expected for DECRA, LIEF & presumably(?) Centres of Excellence ("postponed" on 3 Nov).
Other events:
🔹Open: Discovery Projects EOI
🔹Close: ITRP & Future Fellowships
🔹Selection meeting: Linkage Projects (2025 round 2)
Data ▶️ docs.google.com/spreadsheets...
Reposted by Wai-Hong Tham
Stylidium utricularioides - the Pink Fan Triggerplant
One of the triggerplants endemic to Western Australia, this distinctive species grows in winter wet areas and flowers in late spring through to early summer
#ozflora #wildoz #nativeplants #inaturalist #nature
One of the triggerplants endemic to Western Australia, this distinctive species grows in winter wet areas and flowers in late spring through to early summer
#ozflora #wildoz #nativeplants #inaturalist #nature
November 4, 2025 at 4:06 AM
Stylidium utricularioides - the Pink Fan Triggerplant
One of the triggerplants endemic to Western Australia, this distinctive species grows in winter wet areas and flowers in late spring through to early summer
#ozflora #wildoz #nativeplants #inaturalist #nature
One of the triggerplants endemic to Western Australia, this distinctive species grows in winter wet areas and flowers in late spring through to early summer
#ozflora #wildoz #nativeplants #inaturalist #nature
Reposted by Wai-Hong Tham
#CentresOfExcellence #CE26
ARC has "postponed" announcement of Centres of Excellence outcomes!
It says "due diligence checks" are still being carried out on some applications.
www.arc.gov.au/news-publica...
ARC has "postponed" announcement of Centres of Excellence outcomes!
It says "due diligence checks" are still being carried out on some applications.
www.arc.gov.au/news-publica...
November 3, 2025 at 6:32 AM
#CentresOfExcellence #CE26
ARC has "postponed" announcement of Centres of Excellence outcomes!
It says "due diligence checks" are still being carried out on some applications.
www.arc.gov.au/news-publica...
ARC has "postponed" announcement of Centres of Excellence outcomes!
It says "due diligence checks" are still being carried out on some applications.
www.arc.gov.au/news-publica...
Reposted by Wai-Hong Tham
Stunning illustration of mimicry! Common cuckoo eggs (top row) imitate the eggs of their host species (bottom row). The 30 October issue of Science explains this dazzling coevolution with genomic data — though I admit, it’s complex enough that I’d struggle to teach it! 🧪🌿🌎🦉
November 1, 2025 at 8:42 PM
Stunning illustration of mimicry! Common cuckoo eggs (top row) imitate the eggs of their host species (bottom row). The 30 October issue of Science explains this dazzling coevolution with genomic data — though I admit, it’s complex enough that I’d struggle to teach it! 🧪🌿🌎🦉
Reposted by Wai-Hong Tham
Really interesting interview. @timcoulson.bsky.social and I were also fortunate to chat with David Baker on our podcast which you can catch here: Science Of The Times EP7 Pt2 - Interview with 2024 Nobel Prize winner for Chemistry David Baker
youtu.be/jShxgJ3XrWA
youtu.be/jShxgJ3XrWA
November 2, 2025 at 6:24 PM
Really interesting interview. @timcoulson.bsky.social and I were also fortunate to chat with David Baker on our podcast which you can catch here: Science Of The Times EP7 Pt2 - Interview with 2024 Nobel Prize winner for Chemistry David Baker
youtu.be/jShxgJ3XrWA
youtu.be/jShxgJ3XrWA
Reposted by Wai-Hong Tham
I promised myself that when I next had a successful grant, I'd share a snapshot of my trail of unfunded submissions.
With gratitude to the ARC, looking forward to next several years of collaboration on effort motivation with @minzlicht.bsky.social, Deena Skolnick Weisberg, and Frederik Anseel!
With gratitude to the ARC, looking forward to next several years of collaboration on effort motivation with @minzlicht.bsky.social, Deena Skolnick Weisberg, and Frederik Anseel!
November 2, 2025 at 2:20 AM
I promised myself that when I next had a successful grant, I'd share a snapshot of my trail of unfunded submissions.
With gratitude to the ARC, looking forward to next several years of collaboration on effort motivation with @minzlicht.bsky.social, Deena Skolnick Weisberg, and Frederik Anseel!
With gratitude to the ARC, looking forward to next several years of collaboration on effort motivation with @minzlicht.bsky.social, Deena Skolnick Weisberg, and Frederik Anseel!
Reposted by Wai-Hong Tham
Registrations for the Stromlo Plant Pathogen Conference #StromPath25 are rolling in fast and the program is now full!
Exciting lineup from Japan, Korea, USA, UK, NZ + strong local crew. Join us in Canberra — rego open until Nov 13.
Program available here tinyurl.com/3e3tx9j2
Exciting lineup from Japan, Korea, USA, UK, NZ + strong local crew. Join us in Canberra — rego open until Nov 13.
Program available here tinyurl.com/3e3tx9j2
10th Stromlo Plant Pathology Conference | wheatbiosecurity
tinyurl.com
October 30, 2025 at 7:02 AM
Registrations for the Stromlo Plant Pathogen Conference #StromPath25 are rolling in fast and the program is now full!
Exciting lineup from Japan, Korea, USA, UK, NZ + strong local crew. Join us in Canberra — rego open until Nov 13.
Program available here tinyurl.com/3e3tx9j2
Exciting lineup from Japan, Korea, USA, UK, NZ + strong local crew. Join us in Canberra — rego open until Nov 13.
Program available here tinyurl.com/3e3tx9j2
Reposted by Wai-Hong Tham
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Quick Check Needed
mrc.tal.net
October 29, 2025 at 9:17 AM
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Reposted by Wai-Hong Tham
Plant scientists Professor Graham Farquhar and Professor Susanne von Caemmerer transformed the world's understanding of photosynthesis, and now they have been jointly awarded the Royal Medal (Biological) from The Royal Society, at a ceremony in London.
science.anu.edu.au/news-events/...
science.anu.edu.au/news-events/...
October 27, 2025 at 4:45 AM
Plant scientists Professor Graham Farquhar and Professor Susanne von Caemmerer transformed the world's understanding of photosynthesis, and now they have been jointly awarded the Royal Medal (Biological) from The Royal Society, at a ceremony in London.
science.anu.edu.au/news-events/...
science.anu.edu.au/news-events/...
Keen to use an open source workflow for nanobody discovery? Check out Alpseq 🦙
Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection
Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski
www.biorxiv.org/content/10.1...
Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection
Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski
www.biorxiv.org/content/10.1...
alpseq: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing
Nanobodies have emerged as promising tools for many biotechnological applications due to their small size, high stability, and remarkable binding specificity. Next-Generation Sequencing (NGS) enables ...
www.biorxiv.org
October 27, 2025 at 3:18 AM
Keen to use an open source workflow for nanobody discovery? Check out Alpseq 🦙
Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection
Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski
www.biorxiv.org/content/10.1...
Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection
Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski
www.biorxiv.org/content/10.1...
Reposted by Wai-Hong Tham
We’re hiring an Engagement Officer for the ISC Asia–Pacific Regional Focal Point. Based in Canberra (or remote for the right candidate). Closes 4 November.
Apply now: www.science.org.au/about-us/car... @iscasiapacific.bsky.social
Apply now: www.science.org.au/about-us/car... @iscasiapacific.bsky.social
October 27, 2025 at 1:00 AM
We’re hiring an Engagement Officer for the ISC Asia–Pacific Regional Focal Point. Based in Canberra (or remote for the right candidate). Closes 4 November.
Apply now: www.science.org.au/about-us/car... @iscasiapacific.bsky.social
Apply now: www.science.org.au/about-us/car... @iscasiapacific.bsky.social
Reposted by Wai-Hong Tham
ARC says Discovery Projects outcomes will be tomorrow (Tuesday). Linkage Projects (2025, round 1) on Wed. Over past ~year, it's often been at about 11am (Canberra).
My bot will pick up the change to RMS & post immediately.
ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
My bot will pick up the change to RMS & post immediately.
ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
October 26, 2025 at 11:17 PM
ARC says Discovery Projects outcomes will be tomorrow (Tuesday). Linkage Projects (2025, round 1) on Wed. Over past ~year, it's often been at about 11am (Canberra).
My bot will pick up the change to RMS & post immediately.
ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
My bot will pick up the change to RMS & post immediately.
ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
Reposted by Wai-Hong Tham
Excited to share our new preprint: alpseq - an open-source workflow to turbocharge nanobody discovery! 🦙
doi.org/10.1101/2025...
This work is the result of Kathleen Zeglinski’s brilliant PhD work and an outstanding collaboration with Wai-Hong Tham's group!
Find alpseq at github.com/kzeglinski/a...
doi.org/10.1101/2025...
This work is the result of Kathleen Zeglinski’s brilliant PhD work and an outstanding collaboration with Wai-Hong Tham's group!
Find alpseq at github.com/kzeglinski/a...
alpseq: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing
Nanobodies have emerged as promising tools for many biotechnological applications due to their small size, high stability, and remarkable binding specificity. Next-Generation Sequencing (NGS) enables ...
doi.org
October 24, 2025 at 12:42 AM
Excited to share our new preprint: alpseq - an open-source workflow to turbocharge nanobody discovery! 🦙
doi.org/10.1101/2025...
This work is the result of Kathleen Zeglinski’s brilliant PhD work and an outstanding collaboration with Wai-Hong Tham's group!
Find alpseq at github.com/kzeglinski/a...
doi.org/10.1101/2025...
This work is the result of Kathleen Zeglinski’s brilliant PhD work and an outstanding collaboration with Wai-Hong Tham's group!
Find alpseq at github.com/kzeglinski/a...
Reposted by Wai-Hong Tham
I am fascinated by how viruses evolve - and not just since #SARSCoV2 has shown us at the global stage how consequential virus evolution can be for us.
In my new story in @science.org I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a 🧪 thread…
In my new story in @science.org I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a 🧪 thread…
On an Arctic archipelago, frozen soil may preserve a hidden history of viruses
Scientists are hunting for ancient RNA in Svalbard’s permafrost, hoping to shed light on the evolution of viral diseases
www.science.org
October 18, 2025 at 10:02 AM
I am fascinated by how viruses evolve - and not just since #SARSCoV2 has shown us at the global stage how consequential virus evolution can be for us.
In my new story in @science.org I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a 🧪 thread…
In my new story in @science.org I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a 🧪 thread…
Reposted by Wai-Hong Tham
Attention membrane traffickers! I'm recruiting a post-doc to my lab in Dundee. We're dissecting the functions of intrinsically disordered domains of COPII coat proteins. We think they control timing of coat assembly and morphology of carriers.
www.dundee.ac.uk/work-for-us/...
www.dundee.ac.uk/work-for-us/...
Postdoctoral Research Assistant - MCDB - UOD2016
Closing date: Thursday 6 November 2025, 23:59
www.dundee.ac.uk
October 15, 2025 at 12:53 PM
Attention membrane traffickers! I'm recruiting a post-doc to my lab in Dundee. We're dissecting the functions of intrinsically disordered domains of COPII coat proteins. We think they control timing of coat assembly and morphology of carriers.
www.dundee.ac.uk/work-for-us/...
www.dundee.ac.uk/work-for-us/...
Reposted by Wai-Hong Tham
Congratulations 👏We have a winner for the 2nd ARC CCeMMP Bench to Art Exhibition🥇Our judges awarded the first prize to Laura Humphrys - 'Too Hot To Chandle'! 👏More info on our website: ccemmp.org/events/arc-c...
October 13, 2025 at 4:27 AM
Congratulations 👏We have a winner for the 2nd ARC CCeMMP Bench to Art Exhibition🥇Our judges awarded the first prize to Laura Humphrys - 'Too Hot To Chandle'! 👏More info on our website: ccemmp.org/events/arc-c...
Reposted by Wai-Hong Tham
And congratulations to Muyuan Chen - "Cat jumping from respiratory complex", awarded the third prize at the 2nd ARC CCeMMP Bench to Art Exhibition👏More info on our website: ccemmp.org/events/arc-c...
October 13, 2025 at 6:55 AM
And congratulations to Muyuan Chen - "Cat jumping from respiratory complex", awarded the third prize at the 2nd ARC CCeMMP Bench to Art Exhibition👏More info on our website: ccemmp.org/events/arc-c...
Reposted by Wai-Hong Tham
Congratulations also to Kenta Ishii and the entry 'One and four GLP-1Rs', which was awarded the second prize at the 2nd ARC CCeMMP Bench to Art Exhibition👏More info on our website: ccemmp.org/events/arc-c...
October 13, 2025 at 6:44 AM
Congratulations also to Kenta Ishii and the entry 'One and four GLP-1Rs', which was awarded the second prize at the 2nd ARC CCeMMP Bench to Art Exhibition👏More info on our website: ccemmp.org/events/arc-c...
Reposted by Wai-Hong Tham
Firing measles experts in the midst of a measles outbreak seems highly logical and smart
🤦🏽♂️
🤦🏽♂️
The mass layoffs of federal workers on Friday night swept up the top two leaders of the federal measles response team, even as the nation grapples with the most cases recorded since 2000, when measles was declared eliminated in the U.S.
C.D.C. Layoffs Included 2 Top Measles Experts Amid Rising Cases
Scientists who focused on other infectious diseases, like an Ebola outbreak in the Democratic Republic of Congo, also were let go.
nyti.ms
October 11, 2025 at 9:51 PM
Firing measles experts in the midst of a measles outbreak seems highly logical and smart
🤦🏽♂️
🤦🏽♂️
Reposted by Wai-Hong Tham
Open Group Leader Positions at the IMB, UQ. Interested in joining us in sunny Queensland?
Group Leader - Institute for Molecular Bioscience (IMB)
Institute for Molecular Bioscience Join a university ranked in the world’s top 50 Australia’s #1 research institute Based at St Lucia Campus About UQ What started as Queensland's first university in 1...
uq.wd3.myworkdayjobs.com
October 12, 2025 at 4:17 AM
Open Group Leader Positions at the IMB, UQ. Interested in joining us in sunny Queensland?