Tânia Paulo
@taniafpaulo.bsky.social
Feminist. Humanist. Foodie.
Evolutionary and Organismal Biologist working on host-pathogen interactions and immune response in Drosophila.
Postdoc @ Boston Children's Hospital with microiddoc.bsky.social
Evolutionary and Organismal Biologist working on host-pathogen interactions and immune response in Drosophila.
Postdoc @ Boston Children's Hospital with microiddoc.bsky.social
Reposted by Tânia Paulo
Welcome to Bluesky, European Drosophila Population Genomics Consortium @droseu.bsky.social.
We've added you to the Model Organism Research Resources starter pack go.bsky.app/Npxsd7h
We've added you to the Model Organism Research Resources starter pack go.bsky.app/Npxsd7h
October 19, 2025 at 4:02 PM
Welcome to Bluesky, European Drosophila Population Genomics Consortium @droseu.bsky.social.
We've added you to the Model Organism Research Resources starter pack go.bsky.app/Npxsd7h
We've added you to the Model Organism Research Resources starter pack go.bsky.app/Npxsd7h
Reposted by Tânia Paulo
To learn more about #DrosEU visit
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
DrosEU – European Drosophila Population Genomics Consortium
droseu.net
October 19, 2025 at 9:35 AM
To learn more about #DrosEU visit
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
droseu.net and join us!!
DrosEU has been funded by a @eseb.bsky.social Special Topic Network (7/7)
Reposted by Tânia Paulo
Reposted by Tânia Paulo
Phenotypic divergence among European populations was assayed in 173 isofemale lines, spearheaded by Esra Durmaz Mitchell and Thomas Flatt, we show that populations differed markedly in multivariate trait structure @evolletters.bsky.social @eseb.bsky.social academic.oup.com/evlett/artic... (5/7)
Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of Drosophila melanogaster
Abstract. A particularly well-studied evolutionary model is the vinegar fly Drosophila melanogaster, a cosmopolitan insect of ancestral southern-central Af
academic.oup.com
October 19, 2025 at 9:35 AM
Phenotypic divergence among European populations was assayed in 173 isofemale lines, spearheaded by Esra Durmaz Mitchell and Thomas Flatt, we show that populations differed markedly in multivariate trait structure @evolletters.bsky.social @eseb.bsky.social academic.oup.com/evlett/artic... (5/7)
Reposted by Tânia Paulo
This community effort includes sampling by high school students part of the #citizenscience project #MelanogasterCTF, a joint project between @gonzalezlabbcn.bsky.social and @lcatmon.bsky.social in collaboration with Sònia Casillas @uab.cat, @droseu.bsky.social and #FECYT melanogaster.eu (4/7)
Melanogaster Catch The Fly
melanogaster.eu
October 19, 2025 at 9:35 AM
This community effort includes sampling by high school students part of the #citizenscience project #MelanogasterCTF, a joint project between @gonzalezlabbcn.bsky.social and @lcatmon.bsky.social in collaboration with Sònia Casillas @uab.cat, @droseu.bsky.social and #FECYT melanogaster.eu (4/7)
Reposted by Tânia Paulo
DESTv2 analyses show that the spatial genetic structure of populations is stable over time; identify signatures of adaptation that vary between continents; and provide new evidence for seasonal adaptation @molbioevol.bsky.social @official-smbe.bsky.social : academic.oup.com/mbe/article/... (3/7)
Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource
Abstract. Large-scale genomic resources can place genetic variation into an ecologically informed context. To advance our understanding of the population g
academic.oup.com
October 19, 2025 at 9:35 AM
DESTv2 analyses show that the spatial genetic structure of populations is stable over time; identify signatures of adaptation that vary between continents; and provide new evidence for seasonal adaptation @molbioevol.bsky.social @official-smbe.bsky.social : academic.oup.com/mbe/article/... (3/7)
Reposted by Tânia Paulo
An expanded release of the community-generated population genomics resource DEST, spearheaded by Marta Coronado-Zamora @geneticament.bsky.social and Joaquin Nunez @jcbnunez.bsky.social, is now available at dest.bio (2/7)
Home
“Drosophila Evolution in Space and Time” (DEST) - A New Population Genomics Resource.
dest.bio
October 19, 2025 at 9:35 AM
An expanded release of the community-generated population genomics resource DEST, spearheaded by Marta Coronado-Zamora @geneticament.bsky.social and Joaquin Nunez @jcbnunez.bsky.social, is now available at dest.bio (2/7)
Check the fantastic work from the DrosEU consortium, a collaborative worldwide effort to characterize Drosophila populations 🌍
We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European #Drosophila melanogaster populations (1/7)
October 19, 2025 at 12:48 PM
Check the fantastic work from the DrosEU consortium, a collaborative worldwide effort to characterize Drosophila populations 🌍
😡😡
!!
!!
I just got the notice that all the FlyBase people at Harvard, including me, will be laid off on October 12. I'm devastated.
August 12, 2025 at 5:28 PM
😡😡
!!
!!
Reposted by Tânia Paulo
Comment on our @Reproducibility project in @Drosophila immunity. It is a normal that findings—however exciting and important at the time—may later prove to be more complex than initially believed. Re-evaluations is essential to the self-correcting nature of science. www.science.org/content/arti...
Majority of fruit fly immunity studies can be replicated, huge analysis finds
Verification of 50 years of data bolsters immunology research, but identifies “suspicious” papers that don’t hold up
www.science.org
July 16, 2025 at 8:01 AM
Comment on our @Reproducibility project in @Drosophila immunity. It is a normal that findings—however exciting and important at the time—may later prove to be more complex than initially believed. Re-evaluations is essential to the self-correcting nature of science. www.science.org/content/arti...
Reposted by Tânia Paulo
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
July 10, 2025 at 8:23 AM
The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience
A 🧵 1/n
Reposted by Tânia Paulo
'The myth of meritocracy in science collapses under the financial sacrifices expected at every career stage. From unpaid internships and self-funded conferences to underpaid graduate and postdoctoral positions, the hidden costs of ‘doing science’ are profound.'
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Too poor to science: How wealth determines who succeeds in STEM
From student to researcher, a career in science can come with a high price tag. This Perspective explores how persistent financial barriers limit who can succeed in science, revealing how wealth shape...
journals.plos.org
July 6, 2025 at 12:58 AM
'The myth of meritocracy in science collapses under the financial sacrifices expected at every career stage. From unpaid internships and self-funded conferences to underpaid graduate and postdoctoral positions, the hidden costs of ‘doing science’ are profound.'
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by Tânia Paulo
My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 5:00 PM
My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
Reposted by Tânia Paulo
We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
June 3, 2025 at 9:17 PM
We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.
Reposted by Tânia Paulo
Hidden virus harboured by fruit flies may influence experimental accuracy.
buff.ly/TtHCYLQ
buff.ly/TtHCYLQ
May 10, 2025 at 1:59 PM
Hidden virus harboured by fruit flies may influence experimental accuracy.
buff.ly/TtHCYLQ
buff.ly/TtHCYLQ
Reposted by Tânia Paulo
Thread with an email being sent to @asn-amnat.bsky.social @sse-evolution.bsky.social @systbiol.bsky.social members today calling for a Tri-society week of action for NSF:
Dear members:
The tri-societies (ASN, SSE,SSB) are running a ‘Week of Action for NSF’. Your engagement is crucial.
Dear members:
The tri-societies (ASN, SSE,SSB) are running a ‘Week of Action for NSF’. Your engagement is crucial.
May 5, 2025 at 11:59 AM
Thread with an email being sent to @asn-amnat.bsky.social @sse-evolution.bsky.social @systbiol.bsky.social members today calling for a Tri-society week of action for NSF:
Dear members:
The tri-societies (ASN, SSE,SSB) are running a ‘Week of Action for NSF’. Your engagement is crucial.
Dear members:
The tri-societies (ASN, SSE,SSB) are running a ‘Week of Action for NSF’. Your engagement is crucial.
Reposted by Tânia Paulo
For US students interested in the UK, if you have an acceptance letter from a US college or university, these applications will be considered rapidly at @exeter.ac.uk for the 2025/2026 year.
If you're interested in an MSc or PhD, happy to chat & support. I study #Drosophila #Immunity #Genetics 🪰🦠🧬
If you're interested in an MSc or PhD, happy to chat & support. I study #Drosophila #Immunity #Genetics 🪰🦠🧬
April 30, 2025 at 12:17 PM
For US students interested in the UK, if you have an acceptance letter from a US college or university, these applications will be considered rapidly at @exeter.ac.uk for the 2025/2026 year.
If you're interested in an MSc or PhD, happy to chat & support. I study #Drosophila #Immunity #Genetics 🪰🦠🧬
If you're interested in an MSc or PhD, happy to chat & support. I study #Drosophila #Immunity #Genetics 🪰🦠🧬
Reposted by Tânia Paulo
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
April 10, 2025 at 6:06 AM
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
Reposted by Tânia Paulo
Happy to share our latest minireview on
Drosophila symbionts in infection: when a friend becomes an enemy | Infection and Immunity journals.asm.org/doi/10.1128/...
#immunity #infection #antimicrobialpeptides #microbiome #Drosophila #AcademicSky #insect #endosymbiont #symbiosis
Drosophila symbionts in infection: when a friend becomes an enemy | Infection and Immunity journals.asm.org/doi/10.1128/...
#immunity #infection #antimicrobialpeptides #microbiome #Drosophila #AcademicSky #insect #endosymbiont #symbiosis
Drosophila symbionts in infection: when a friend becomes an enemy | Infection and Immunity
Occupying the interface between host and environment, host-associated microbes play
essential roles in interactions with pathogens and influence disease progression (1–4). Considering that most entry ...
journals.asm.org
April 4, 2025 at 1:07 PM
Happy to share our latest minireview on
Drosophila symbionts in infection: when a friend becomes an enemy | Infection and Immunity journals.asm.org/doi/10.1128/...
#immunity #infection #antimicrobialpeptides #microbiome #Drosophila #AcademicSky #insect #endosymbiont #symbiosis
Drosophila symbionts in infection: when a friend becomes an enemy | Infection and Immunity journals.asm.org/doi/10.1128/...
#immunity #infection #antimicrobialpeptides #microbiome #Drosophila #AcademicSky #insect #endosymbiont #symbiosis
Reposted by Tânia Paulo
Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity.
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
Layers of immunity: Deconstructing the Drosophila effector response
The host innate immune response relies on the cooperation of multiple defense modules. In insects and other arthropods, which have only innate immune mechanisms, four main immune-specific modules cont...
www.biorxiv.org
April 1, 2025 at 8:34 AM
Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity.
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?
1/n 🧵
Reposted by Tânia Paulo
Many congratulations to #Drosophila researcher Helen Skaer for winning the BSDB Waddington Medal! A fantastic scientist, teacher and advocate for developmental biology.
We are delighted to announce that the winner of the 2025 Waddington Medal is Helen Skaer!
bsdb.org/2025/03/25/2...
bsdb.org/2025/03/25/2...
March 25, 2025 at 5:44 PM
Many congratulations to #Drosophila researcher Helen Skaer for winning the BSDB Waddington Medal! A fantastic scientist, teacher and advocate for developmental biology.
Check out the final version of our paper! With the brilliant @abenaakyaw.bsky.social , we showed that resistance and disease tolerance mechanisms evolved in tandem to enable a fast and strong response to oral bacterial infection in #Dmelanogaster. #hostparasite #experimentalevolution
Time to give an update on the fantastic work by @taniafpaulo.bsky.social during her PhD, now published in @royalsocietypublishing.org on the evolution of resistance and disease tolerance mechanisms to oral infection in #Drosophila
royalsocietypublishing.org/doi/10.1098/...
#infection #immunity 🤓🎊
royalsocietypublishing.org/doi/10.1098/...
#infection #immunity 🤓🎊
Evolution of resistance and disease tolerance mechanisms to oral bacterial infection in Drosophila melanogaster | Open Biology
Pathogens exert strong selection on hosts that evolve and deploy different defensive
strategies, namely minimizing pathogen exposure (avoidance), directly promoting pathogen
elimination (resistance) a...
royalsocietypublishing.org
March 15, 2025 at 12:22 PM
Check out the final version of our paper! With the brilliant @abenaakyaw.bsky.social , we showed that resistance and disease tolerance mechanisms evolved in tandem to enable a fast and strong response to oral bacterial infection in #Dmelanogaster. #hostparasite #experimentalevolution
Reposted by Tânia Paulo
Stand up for science, Boston! Big crowd!
March 8, 2025 at 12:10 AM
Stand up for science, Boston! Big crowd!
Reposted by Tânia Paulo
NEW: The NIH has begun terminating grants for active projects studying gender identity, DEI, environmental justice, climate change, among other topics.
At least 16 termination letters have already been sent — and hundreds more are coming, people inside NIH tell me.
www.nature.com/articles/d41...
At least 16 termination letters have already been sent — and hundreds more are coming, people inside NIH tell me.
www.nature.com/articles/d41...
Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
www.nature.com
March 6, 2025 at 2:17 AM
NEW: The NIH has begun terminating grants for active projects studying gender identity, DEI, environmental justice, climate change, among other topics.
At least 16 termination letters have already been sent — and hundreds more are coming, people inside NIH tell me.
www.nature.com/articles/d41...
At least 16 termination letters have already been sent — and hundreds more are coming, people inside NIH tell me.
www.nature.com/articles/d41...