Stefan Bassler
@stefanbassler.bsky.social
@embl.org PhD & Bridging Excellence Postdoc (LifeScienceAlliance) with
@petrovadmitri.bsky.social @stanford.edu and Aulehla & Steinmetz labs @embl.org using #SystemsEvolution to study #Aging
@petrovadmitri.bsky.social @stanford.edu and Aulehla & Steinmetz labs @embl.org using #SystemsEvolution to study #Aging
Pinned
Pioneering Transatlantic Collaboration – EMBL | Stanford Life Science Alliance
www.embl.org
Excited to announce that I started as a Bridging Excellence Fellow with @petrovadmitri.bsky.social @stanforduniversity.bsky.social and Aulehla & Steinmetz @embl.org to find genetic modulators of lifespan using evolution. I'm incredibly grateful to LSA for their funding.
www.embl.org/about/info/l...
www.embl.org/about/info/l...
Reposted by Stefan Bassler
Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 11, 2025 at 5:15 PM
Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Stefan Bassler
For population genetics and evolutionary biology folks in the Bay Area: the next BAPG will be hosted by Stanford CEHG and the Petrov lab at Stanford on 12/6.
Registration is free but required. The deadline for talk submission is Nov. 16. Hope to see you soon! Pls RT!
docs.google.com/forms/d/e/1F...
Registration is free but required. The deadline for talk submission is Nov. 16. Hope to see you soon! Pls RT!
docs.google.com/forms/d/e/1F...
docs.google.com
October 20, 2025 at 10:42 PM
For population genetics and evolutionary biology folks in the Bay Area: the next BAPG will be hosted by Stanford CEHG and the Petrov lab at Stanford on 12/6.
Registration is free but required. The deadline for talk submission is Nov. 16. Hope to see you soon! Pls RT!
docs.google.com/forms/d/e/1F...
Registration is free but required. The deadline for talk submission is Nov. 16. Hope to see you soon! Pls RT!
docs.google.com/forms/d/e/1F...
Reposted by Stefan Bassler
Job alert🚨📢! Join us as Director of the SIB Centre for Pathogen Bioinformatics, on a topic where global collaboration is particularly important, in a highly stimulating environment. This is a research infrastructure leadership position.
Apply or spread the word!
apply.refline.ch/499599/0346/...
Apply or spread the word!
apply.refline.ch/499599/0346/...
Director, Center for Pathogen Bioinformatics
The Centre for Pathogen Bioinformatics (CPB) is a unit of SIB which offers expertise and services in pathogen bioinformatics, computational molecular epidemiology and related multi-site project manage...
apply.refline.ch
October 23, 2025 at 5:34 AM
Job alert🚨📢! Join us as Director of the SIB Centre for Pathogen Bioinformatics, on a topic where global collaboration is particularly important, in a highly stimulating environment. This is a research infrastructure leadership position.
Apply or spread the word!
apply.refline.ch/499599/0346/...
Apply or spread the word!
apply.refline.ch/499599/0346/...
Reposted by Stefan Bassler
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation
The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and n...
www.biorxiv.org
October 22, 2025 at 5:46 PM
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Stefan Bassler
#Perspective
Estrela and Huang discuss nutrient starvation in the context of the gut microbiome, outlining what is known and highlighting key questions for future research to address knowledge gaps.
#MicroSky #MicrobiomeSky 🦠
www.nature.com/articles/s41...
Estrela and Huang discuss nutrient starvation in the context of the gut microbiome, outlining what is known and highlighting key questions for future research to address knowledge gaps.
#MicroSky #MicrobiomeSky 🦠
www.nature.com/articles/s41...
How nutrient starvation impacts the gut microbiome - Nature Microbiology
In this Perspective, Estrela and Huang discuss nutrient starvation in the context of the gut microbiome, outlining what is known and highlighting key questions for future research to address knowledge gaps.
www.nature.com
October 1, 2025 at 5:56 PM
#Perspective
Estrela and Huang discuss nutrient starvation in the context of the gut microbiome, outlining what is known and highlighting key questions for future research to address knowledge gaps.
#MicroSky #MicrobiomeSky 🦠
www.nature.com/articles/s41...
Estrela and Huang discuss nutrient starvation in the context of the gut microbiome, outlining what is known and highlighting key questions for future research to address knowledge gaps.
#MicroSky #MicrobiomeSky 🦠
www.nature.com/articles/s41...
Reposted by Stefan Bassler
Excited to share our preprint led by Carlos Voogdt et al
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
October 13, 2025 at 7:48 AM
Excited to share our preprint led by Carlos Voogdt et al
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
Reposted by Stefan Bassler
Looking to start your own lab? 🧬🧪 The Helmholtz Institute Würzburg (HIRI) is offering group leader positions in RNA biology, RNA medicine & RNA technology. Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
E15 Groups
The Helmholtz Institute for RNA-based Infection Researchopens a call for
www.helmholtz-hiri.de
October 13, 2025 at 1:30 PM
Looking to start your own lab? 🧬🧪 The Helmholtz Institute Würzburg (HIRI) is offering group leader positions in RNA biology, RNA medicine & RNA technology. Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
Reposted by Stefan Bassler
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
October 8, 2025 at 9:45 PM
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
Reposted by Stefan Bassler
📣The 2026 ERC Consolidator Grant competition is now open! 📣
Already preparing your proposal? Info links ⬇️
Info for applicants 👉 buff.ly/PSbeUxX
Application portal 👉 buff.ly/mauZoqo
Deadline: 13/01/26
General info on #ERCCoG 👉 buff.ly/KCN6GTh
Already preparing your proposal? Info links ⬇️
Info for applicants 👉 buff.ly/PSbeUxX
Application portal 👉 buff.ly/mauZoqo
Deadline: 13/01/26
General info on #ERCCoG 👉 buff.ly/KCN6GTh
September 26, 2025 at 2:30 PM
📣The 2026 ERC Consolidator Grant competition is now open! 📣
Already preparing your proposal? Info links ⬇️
Info for applicants 👉 buff.ly/PSbeUxX
Application portal 👉 buff.ly/mauZoqo
Deadline: 13/01/26
General info on #ERCCoG 👉 buff.ly/KCN6GTh
Already preparing your proposal? Info links ⬇️
Info for applicants 👉 buff.ly/PSbeUxX
Application portal 👉 buff.ly/mauZoqo
Deadline: 13/01/26
General info on #ERCCoG 👉 buff.ly/KCN6GTh
Reposted by Stefan Bassler
Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...
September 15, 2025 at 9:27 AM
Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...
Reposted by Stefan Bassler
Open Call for Expressions of Interest: become a Max Planck Director & redefine what’s possible in science! We offer scientific independence, long-term stable funding & exceptional infrastructure. Lead your own department & open new frontiers of research. Apply by 31 Oct 2025 → www.mpg.de/directors
Directors
The Max Planck Society offers Directors a unique platform for groundbreaking research and leadership in diverse scientific fields.
www.mpg.de
September 17, 2025 at 3:25 PM
Open Call for Expressions of Interest: become a Max Planck Director & redefine what’s possible in science! We offer scientific independence, long-term stable funding & exceptional infrastructure. Lead your own department & open new frontiers of research. Apply by 31 Oct 2025 → www.mpg.de/directors
Reposted by Stefan Bassler
Very excited to see this work in press! I think there is a reason to believe that this is a common means of stabilizing large-effect polymorphisms in general and might be an important reason for why diploidy is so common. news.stanford.edu/stories/2025...
September 15, 2025 at 5:24 PM
Very excited to see this work in press! I think there is a reason to believe that this is a common means of stabilizing large-effect polymorphisms in general and might be an important reason for why diploidy is so common. news.stanford.edu/stories/2025...
Reposted by Stefan Bassler
How do populations maintain an evolutionary memory? I am happy to share that our work with Dmitri Petrov @petrovadmitri.bsky.social, Paul Schmidt, and colleagues on dominance reversal and stabilization of insecticide resistance in changing environments over time is now published at Nature EE.
Beneficial reversal of dominance maintains a large-effect resistance polymorphism under fluctuating insecticide selection - Nature Ecology & Evolution
Measuring selection and dominance in fitness of the insecticide-resistant Ace alleles in Drosophila melanogaster, the authors show evidence for beneficial reversal of dominance, a mechanism that can s...
www.nature.com
September 15, 2025 at 6:17 PM
How do populations maintain an evolutionary memory? I am happy to share that our work with Dmitri Petrov @petrovadmitri.bsky.social, Paul Schmidt, and colleagues on dominance reversal and stabilization of insecticide resistance in changing environments over time is now published at Nature EE.
Reposted by Stefan Bassler
California is devising a plan to create their own National Institutes of Health to counter federal cuts to science research.
California’s $23 Billion Plan to Restore Federal Cuts to Scientific Research
www.nytimes.com
September 13, 2025 at 10:23 PM
California is devising a plan to create their own National Institutes of Health to counter federal cuts to science research.
Reposted by Stefan Bassler
The final chapter of my PhD thesis is now out! 🎉 We compared the latest gene regulatory network (#GRN) inference methods for #single-cell multimodal datasets and evaluated their performance across various tasks. Hard to believe this journey started in March 2021 and has finally reached this point 😅🥳
We present Gene Regulatory nETwork Analsyis (GRETA), a framework to infer, compare and evaluate gene regulatory networks #GRNs. With it, we have benchmarked multimodal and unimodal GRN inference methods. Check the results here 👇
Paper: doi.org/10.1101/2024.12.20.629764
Code: github.com/saezlab/greta
Paper: doi.org/10.1101/2024.12.20.629764
Code: github.com/saezlab/greta
December 23, 2024 at 8:49 AM
The final chapter of my PhD thesis is now out! 🎉 We compared the latest gene regulatory network (#GRN) inference methods for #single-cell multimodal datasets and evaluated their performance across various tasks. Hard to believe this journey started in March 2021 and has finally reached this point 😅🥳
Reposted by Stefan Bassler
Join EMBL AI!
We have ambitious plans to transform life sciences research through AI.
Interested in using ML/AI to solve complex interdisciplinary challenges?
We’re looking for two senior leaders based at EMBL Heidelberg👇
We have ambitious plans to transform life sciences research through AI.
Interested in using ML/AI to solve complex interdisciplinary challenges?
We’re looking for two senior leaders based at EMBL Heidelberg👇
September 11, 2025 at 7:24 AM
Join EMBL AI!
We have ambitious plans to transform life sciences research through AI.
Interested in using ML/AI to solve complex interdisciplinary challenges?
We’re looking for two senior leaders based at EMBL Heidelberg👇
We have ambitious plans to transform life sciences research through AI.
Interested in using ML/AI to solve complex interdisciplinary challenges?
We’re looking for two senior leaders based at EMBL Heidelberg👇
Reposted by Stefan Bassler
New academic faculty posts available at Imperial College London! Assistant/Associate Professors in Life Sciences. Please apply and/or circulate details!
www.imperial.ac.uk/jobs/search-...
www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
August 18, 2025 at 8:25 AM
New academic faculty posts available at Imperial College London! Assistant/Associate Professors in Life Sciences. Please apply and/or circulate details!
www.imperial.ac.uk/jobs/search-...
www.imperial.ac.uk/jobs/search-...
Reposted by Stefan Bassler
The Perseverance rover on Mars has observed unusual minerals associated with organic matter — raising questions about the geochemistry of ancient Mars.
go.nature.com/469V1nr
go.nature.com/469V1nr
Mystery Martian minerals hint at the planet’s complex geochemical past
The Perseverance rover on Mars has observed unusual minerals associated with organic matter — raising questions about the geochemistry of ancient Mars.
go.nature.com
September 10, 2025 at 3:35 PM
The Perseverance rover on Mars has observed unusual minerals associated with organic matter — raising questions about the geochemistry of ancient Mars.
go.nature.com/469V1nr
go.nature.com/469V1nr
Reposted by Stefan Bassler
Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…
September 10, 2025 at 3:40 PM
Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…
Reposted by Stefan Bassler
🚨 We’re hiring! Oxford Biology is recruiting 3 new Associate Professors in:
🌱 Plant Sciences
🦉 Animal Behaviour
🔬 Molecular Cell Biology
Join us as we move into our new building with world-class research & teaching facilities.
Vacancies 👉 bit.ly/488CNW3
View our video here: youtu.be/TZa1x0oyqA0
🌱 Plant Sciences
🦉 Animal Behaviour
🔬 Molecular Cell Biology
Join us as we move into our new building with world-class research & teaching facilities.
Vacancies 👉 bit.ly/488CNW3
View our video here: youtu.be/TZa1x0oyqA0
Oxford Biology in the LaMB
YouTube video by Oxford Biology
youtu.be
September 8, 2025 at 3:13 PM
🚨 We’re hiring! Oxford Biology is recruiting 3 new Associate Professors in:
🌱 Plant Sciences
🦉 Animal Behaviour
🔬 Molecular Cell Biology
Join us as we move into our new building with world-class research & teaching facilities.
Vacancies 👉 bit.ly/488CNW3
View our video here: youtu.be/TZa1x0oyqA0
🌱 Plant Sciences
🦉 Animal Behaviour
🔬 Molecular Cell Biology
Join us as we move into our new building with world-class research & teaching facilities.
Vacancies 👉 bit.ly/488CNW3
View our video here: youtu.be/TZa1x0oyqA0
Reposted by Stefan Bassler
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
September 9, 2025 at 12:10 PM
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
Reposted by Stefan Bassler
A call for W 3 (full) professorship in Molecular and Evolutionary Zoology is now open at our department. Join our community of evolutionary biologists! Excellent facilities and scientific environment!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
W 3 professorship in Molecular and Evolutionary Zoology - Kiel, Schleswig-Holstein (DE) job with Christian-Albrechts-Universität zu Kiel | 12844416
Kiel University aims to attract more qualified women to professorship positions. The Institute of Zoology at the Faculty of Mathematics and Natural...
www.nature.com
September 5, 2025 at 8:31 AM
A call for W 3 (full) professorship in Molecular and Evolutionary Zoology is now open at our department. Join our community of evolutionary biologists! Excellent facilities and scientific environment!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by Stefan Bassler
Delighted to see @sakshikhaiwal.bsky.social work in print www.embopress.org/doi/full/10....
Huge thank to @univcotedazur.bsky.social for providing extensive support on this project, @pedrobeltrao.bsky.social and Jonas groups for huge help, @cnrs.fr @ircan.bsky.social
Huge thank to @univcotedazur.bsky.social for providing extensive support on this project, @pedrobeltrao.bsky.social and Jonas groups for huge help, @cnrs.fr @ircan.bsky.social
Predicting natural variation in the yeast phenotypic landscape with machine learning | Molecular Systems Biology
imageimageAn ensemble of phenotypes measured in the genome-sequenced 1,011 S. cerevisiae collection were coupled with genomics and molecular-level data to benchmark machine learning models for quantitative phenotypic predictions at scale. Large-...
www.embopress.org
September 1, 2025 at 9:13 AM
Delighted to see @sakshikhaiwal.bsky.social work in print www.embopress.org/doi/full/10....
Huge thank to @univcotedazur.bsky.social for providing extensive support on this project, @pedrobeltrao.bsky.social and Jonas groups for huge help, @cnrs.fr @ircan.bsky.social
Huge thank to @univcotedazur.bsky.social for providing extensive support on this project, @pedrobeltrao.bsky.social and Jonas groups for huge help, @cnrs.fr @ircan.bsky.social
Reposted by Stefan Bassler
Come join the Baker Heart and Diabetes Institute @bakerresearchau.bsky.social as a Lab Head in Biomedical Data Science 📣 www.baker.edu.au/career/head-...
There's never been a more exciting time to lead a research program in this area... and have work-life balance to boot!
There's never been a more exciting time to lead a research program in this area... and have work-life balance to boot!
Career opportunities at the Baker Heart and Diabetes Institute
The Baker Heart and Diabetes Institute is an independent, internationally renowned medical research facility. We have a long and distinguished history, spanning more than 97 years with our work critic...
www.baker.edu.au
August 30, 2025 at 2:41 PM
Come join the Baker Heart and Diabetes Institute @bakerresearchau.bsky.social as a Lab Head in Biomedical Data Science 📣 www.baker.edu.au/career/head-...
There's never been a more exciting time to lead a research program in this area... and have work-life balance to boot!
There's never been a more exciting time to lead a research program in this area... and have work-life balance to boot!
Reposted by Stefan Bassler
Time to accelerate! ⏱️4 weeks left to apply for EMBL ARISE2 fellowship programme.
Are you interested in developing or improving technologies for life science research? #ARISE2 trains you to become a future research infrastructure leader. 🧪
Apply now! www.embl.org/training/ari...
#careers
Are you interested in developing or improving technologies for life science research? #ARISE2 trains you to become a future research infrastructure leader. 🧪
Apply now! www.embl.org/training/ari...
#careers
September 2, 2025 at 8:14 AM
Time to accelerate! ⏱️4 weeks left to apply for EMBL ARISE2 fellowship programme.
Are you interested in developing or improving technologies for life science research? #ARISE2 trains you to become a future research infrastructure leader. 🧪
Apply now! www.embl.org/training/ari...
#careers
Are you interested in developing or improving technologies for life science research? #ARISE2 trains you to become a future research infrastructure leader. 🧪
Apply now! www.embl.org/training/ari...
#careers