Sri Narasimhan
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snarasimhan.bsky.social
Sri Narasimhan
@snarasimhan.bsky.social
1K followers 1.5K following 21 posts
Scientist and Deputy Editor, Cell at Cell Press
All things science with a love for #microbes, #immunology & #metabolism #sciencesky #womeninSTEM - Opinions and posts are my own. 🇺🇸🇮🇳
https://www.cell.com/cell/editors-and-staff
Posts Replies Media Videos
Reposted by Sri Narasimhan
ekerdoncuff.bsky.social
Our paper out today: 50,000 years of evolutionary history of India: Impact on health and disease variation: Cell www.cell.com/cell/fulltex...
50,000 years of evolutionary history of India: Impact on health and disease variation
A genomic study of 2,762 individuals from India offers important insights into the genomic diversity and evolutionary history of the subcontinent and highlights the extensive genetic variation, gene f...
www.cell.com
June 26, 2025 at 3:27 PM
Reposted by Sri Narasimhan
dianafulmer.bsky.social
Did you know that sea slugs steal chloroplasts from algae as portable snacks?! Neither did I, but a new Cell paper demonstrates that they do. 🐌🧪

My favorite part is the researchers called the storage for these stolen hors d’oeuvres “kleptosomes” 😂🥰

Summary from Nature & Cell paper linked below.
‘Wildest thing’: solar-powered slug steals chloroplasts and stores them for emergencies
Marine creatures house contraband structures in special organelles, which the animal raids for food in times of need.
www.nature.com
June 27, 2025 at 8:53 PM
snarasimhan.bsky.social
Cell is hiring! 4 full-time Scientific Editors - candidates should have an PhD or MD + expertise in cancer/immunology, genetics/genomics, clinical/translational, OR computational biology/AI. Locations: Amsterdam, London, Barcelona, Tokyo, Beijing, Shanghai. Experience is a + tinyurl.com/3rrtvtrj
Elsevier Jobs
Elsevier is a global information analytics business that helps institutions and professionals advance healthcare, open science and improve performance for the benefit of humanity. We help researchers ...
tinyurl.com
May 29, 2025 at 4:35 PM
Reposted by Sri Narasimhan
alleninstitute.org
We've launched the Armamentarium, a new toolkit for targeted gene delivery to the brain and spinal cord.

This #OpenScience resource was made possible thanks to support from the NIH BRAIN Initiative and teamwork with our collaborators.

🧠📈 www.nih.gov/news-events/...
Scientists design gene delivery systems for cells in the brain and spinal cord
NIH-funded breakthrough could enable targeted therapies for many neurological disorders.
www.nih.gov
May 21, 2025 at 6:25 PM
Reposted by Sri Narasimhan
asaelroichman.bsky.social
Thrilled to share that my main postdoctoral project in Josh Rabinowitz’s lab is out today at @cp-cell.bsky.social ! We found an unexpected, diet- and microbiota-dependent mechanism that affects the anticancer activity of PI3K inhibitors. Thread below 👇
May 19, 2025 at 8:15 PM
Reposted by Sri Narasimhan
madhupai.bsky.social
Call for Nominations!!

The 2025 Paul Farmer Lectureship and Award for Global Health Equity

www.mcgill.ca/spgh/about-u...
May 8, 2025 at 10:21 PM
Reposted by Sri Narasimhan
toddmacfarlan.bsky.social
I am looking for postdocs to join my group at NIH. Are you interested in Development, Evolution, Genetics, Genomics, and Human health? Please apply! www.training.nih.gov/jobs/pdf-mb-...
www.training.nih.gov
April 29, 2025 at 2:59 PM
Reposted by Sri Narasimhan
harmitmalik.bsky.social
Interested in postdoc opportunities in Seattle, WA? Join us May 6th for Seattle DROP, a virtual event about biomedical research in Seattle. Hear from recruiting faculty, finding the right mentor and enjoy lunch on us via a delivery voucher within the US!

Registration: tinyurl.com/seattledrop25
Seattle DROP: Discover Research Opportunities for Postdocs
tinyurl.com
April 16, 2025 at 3:28 PM
Reposted by Sri Narasimhan
cp-cell.bsky.social
Now online! Asian diversity in human immune cells
Asian diversity in human immune cells
The Asian Immune Diversity Atlas (AIDA) is a 5-nation single-cell reference atlas of circulating immune cells from healthy donors in diverse populations. AIDA highlights the impact of sub-continental human diversity on immune cell traits implicated in…
dlvr.it
March 19, 2025 at 10:38 PM
Reposted by Sri Narasimhan
cellpress.bsky.social
Check out our #50ScientistsThatInspire interviews with Drs. Madhukar Pai, Johanna Joyce, Juan-Pablo Correa-Baena, & Hanna Kokko threaded below🧵

@madhupai.bsky.social @johannajoyce.bsky.social @jpcorreabaena.bsky.social @kokkonut.bsky.social
Cell Press banner that reads "50 Scientists that Inspire: Putting a spotlight on researchers who drive innovation" The headshots of Drs. Madhukar Pai, Johanna Joyce, Juan-Pablo Correa-Baena, & Hanna Kokko are illuminated under a spotlight.
March 19, 2025 at 4:06 PM
Reposted by Sri Narasimhan
cp-cell.bsky.social
Now online! Microtubules in Asgard archaea
Microtubules in Asgard archaea
Discovery of heterodimeric, microtubule-forming tubulins in Asgard archaea, the closest known relatives of eukaryotes, reveals snapshots of microtubule evolution.
dlvr.it
March 21, 2025 at 6:51 PM
Reposted by Sri Narasimhan
therealdoctort.bsky.social
I remember the cystic fibrosis patients I took care of 20 years ago.

I also remember the dedicated HIV wards in the hospitals, and that Princess Diana made headlines for shaking hands with AIDS patients.

Progress has been incredible.

Miracles are where you choose to see them.
Screenshot of tweet from @AlecStapp “Too many people take biomedical innovation for granted.” Below this is a screenshot from an article on the Atlantic.com. Highlighted is the text: “A child born with cystic fibrosis in the 50s could expect to live until age 5. In the 70s, age 10. In the early 2000s, age 35. With Trikafta came a quantum leap. Today those who begin taking the drug in early adolescence, a recent study projected, can expect to survive to age 82.5 - an essentially normal lifespan.”
March 15, 2025 at 2:30 AM
snarasimhan.bsky.social
The most uplifting and energizing afternoon #StandupforScience #Boston
March 8, 2025 at 2:09 AM
snarasimhan.bsky.social
Our world is incredible and we need science to lead the way. Today at Cell we proudly publish 3 papers exploring life in the deepest depths of the ocean - the Mariana Trench! Read about the MEER package fm Xing Xiao et al tinyurl.com/y5xf49dv @cp-cell.bsky.social & the papers tinyurl.com/yupkvr9v 👇
March 6, 2025 at 5:23 PM
Reposted by Sri Narasimhan
cellpress.bsky.social
Following the NIH decision to cap funding for indirect cost reimbursements at 15%, @nygenome.org Scientific Director Tom Maniatis calls for swift, united action. cell.com/cell/fulltex...

Read his Commentary now in @cp-cell.bsky.social
March 3, 2025 at 4:14 PM
Reposted by Sri Narasimhan
ljrissler.bsky.social
The National Science Foundation benefits communities in every state.
NSF fact sheet
March 2, 2025 at 11:02 PM
Reposted by Sri Narasimhan
erictopol.bsky.social
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
March 1, 2025 at 6:07 PM
snarasimhan.bsky.social
Safeguarding the future of biomedical science in the United States - out in Cell

www.cell.com/cell/fulltex...
Safeguarding the future of biomedical science in the United States
NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical infrastructure supporting groundbreaking biomedical research in the United States. This policy jeopardizes Americ...
www.cell.com
March 1, 2025 at 12:52 AM
Reposted by Sri Narasimhan
pih.org
2/2 Paul showed us that health care is a human right—not a privilege. His moral clarity continues to guide us.

@madhupai.bsky.social captures why his work matters now more than ever, read more at @forbes.com: www.forbes.com/sites/madhuk...
Paul Farmer’s Moral Clarity Offers Hope, Amidst Chaos And Darkness
On the 3rd anniversary of Dr Paul Farmer's death, several leaders reflect on his lessons for dealing with the ongoing crisis in global health and development
www.forbes.com
February 21, 2025 at 8:00 PM
Reposted by Sri Narasimhan
drpanmd.bsky.social
#Measles is not done after the rash has gone away. Measles infections are followed by more disease. #science
www.nbcnews.com/news/amp/rcn...
Measles infections and symptoms pose far more longterm risks than most realize
The virus can cause “immune amnesia,” leaving patients more vulnerable to other infections.
www.nbcnews.com
February 15, 2025 at 4:27 PM
Reposted by Sri Narasimhan
drluiso.bsky.social
If you are an NIH or CDC scientist that lost your job, we have a home for you at UTHealth. I’m hiring physician scientists and we also have transplant ID fellowship slots open. Contact me. #IDSky #MedSky
February 15, 2025 at 11:17 AM
Reposted by Sri Narasimhan
harmitmalik.bsky.social
Someone awesome in my circle shared some terrific news with me today but was hesitant to do so because of all that is going on in the science world.

It may appear insensitive that you are celebrating when other colleagues are struggling but I entreat you to celebrate & share good news. 1/
February 15, 2025 at 2:03 AM
Reposted by Sri Narasimhan
neilshubin.bsky.social
Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.
February 8, 2025 at 1:45 PM
Reposted by Sri Narasimhan
veeslerlab.bsky.social
In these 2 papers, we show that two merbecovirus clades (HKU5 & MOW15-22, distantly related to MERS-CoV) independently evolved ACE2 receptor utilization, reshaping our understanding of coronavirus evolution

Led by Young-Jun Park on our side!

@hhmi.bsky.social

www.cell.com/cell/fulltex...
Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses
The family of coronaviruses known as merbecoviruses has generally been thought to use the host cell protein DPP4 for entry, but this study shows that the merbecovirus HKU5 can enter host cells of the ...
www.cell.com
February 7, 2025 at 4:12 PM
Reposted by Sri Narasimhan
veeslerlab.bsky.social
With participation of Jimin Lee, Jack Brown, Risako Gen, @dabiophysicist.bsky.social, Cameron Stewart in our lab & in collaboration with the labs of Huan Yan and Tyler Starr

www.cell.com/cell/fulltex...
Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses
Two coronaviruses related to MERS-CoV, which infect European Pipistrellus bats, have been found to use ACE2 as their receptor. These viruses target an ACE2 surface region distant from those recognized...
www.cell.com
February 7, 2025 at 4:12 PM