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sfb1453.bsky.social
SFB 1453 NephGen
@sfb1453.bsky.social
97 followers 140 following 20 posts
NephGen brings together scientists who use genetic evidence and innovative transdisciplinary approaches to prevent and treat kidney diseases.
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sfb1453.bsky.social
Pascal Schlosser and Matthias Wuttke, our
@sfb1453.bsky.social representation and speakers at this year's #kidneywk
November 12, 2025 at 7:10 PM
sfb1453.bsky.social
Congratulations to @sfb1453.bsky.social PI Tobias Hermle and his team for their groundbreaking work on slit diaphragm architecture. Go check it out 👇

rdcu.be/eOzXF
The slit diaphragm in Drosophila exhibits a bilayered, fishnet architecture
Nature Communications - The slit diaphragm is a key component of the glomerular filter. This study reveals that the slit diaphragm of Drosophila nephrocytes exhibits a fishnet architecture,...
rdcu.be
November 6, 2025 at 12:07 PM
Reposted by SFB 1453 NephGen
s-monteiromartins.bsky.social
Our study on the genetic determinants of kidney structure is available online in Kidney International as a pre-proof!

We used a CNN to derive kidney sub-volumes from MRIs and performed a GWAS to uncover their genetic determinants.

Thanks to all involved!
#CKD #Imaging #DeepLearning #GWAS
October 28, 2025 at 10:55 AM
sfb1453.bsky.social
A massive shoutout to our @sfb1453.bsky.social colleague Nora Scherer from Anna Köttgen's group for receiving the @dgfn.bsky.social Rainer-Greger-Award for her outstanding dissertation! Congratulations and so well deserved!!! 🎉👏
October 27, 2025 at 12:44 PM
sfb1453.bsky.social
We are delighted that our external advisory board member @ksusztak.bsky.social will be receiving this year’s Homer Smith Award at Kidney Week 2025. www.kidneynews.org/view/journal...
Congratulations Katalin, so well deserved! 👏👏💐
www.kidneynews.org
October 12, 2025 at 8:31 PM
sfb1453.bsky.social
Brilliant presentations by our NephGen PIs Anna Köttgen, Ulla Schultheiss, Michael Köttgen and Sven Diederichs in the @sfb1453.bsky.social session at this year's Annual Meeting of the @dgfn.bsky.social
#Nephrologie #dgfn
October 7, 2025 at 3:33 PM
Reposted by SFB 1453 NephGen
ajkd.bsky.social
Association of Serum Afamin Concentrations With Kidney Failure in Patients With CKD: Findings From the German CKD Cohort Study

bit.ly/4fWGYES #OpenAccess

#VisualAbstract
August 30, 2025 at 10:00 PM
sfb1453.bsky.social
Super cool project! Maybe it's time for a NephGen comic? 🤔
hudrewthis.bsky.social Caroline Hu @hudrewthis.bsky.social · Aug 20
Seeking scientist volunteers for this fall! Want to practice science communication and help author a 🌟comic🌟 about your research? I need collaborators for the next cohort of SciComm & Comics art and design students. All countries and scientific fields eligible.
An anole extends its dewlap, which says "call for scientists!"
August 22, 2025 at 10:29 AM
sfb1453.bsky.social
Thank you to everyone who joined this years' EUKISS Summer School!!! 🎉🙏 It was an amazing meeting with lovely people, impressive science and hopefully many future collaborations and projects. 😍 See you next year in Aachen! #EUKISS25 #EUKISS
July 11, 2025 at 12:26 PM
Reposted by SFB 1453 NephGen
walenteklab.bsky.social
Huge congratulations to Dr. Magdalena Brislinger-Engelhardt for defending her PhD thesis today 👏👏👏🥳🥳🥳
May 28, 2025 at 4:05 PM
sfb1453.bsky.social
Registration for this year’s EUKISS summer school in Freiburg, Germany, is now open! Join us in July for two days of discussions around the basis of kidney functions and their relevance for kidney disease!

Registration & program ➡️ www.eukiss.org
May 28, 2025 at 2:41 PM
Reposted by SFB 1453 NephGen
olegborisovphd.bsky.social
🧬 Looking forward to presenting at the #ESHG2025! Our GWAS & EWAS studies of 10,000+ individuals reveal how genetics & epigenetics regulate trace element metabolism. Visit our poster P18.057.D today at 4pm! Huge thanks to @sfb1453.bsky.social, @zkutalik.bsky.social, and all collaborators involved!
May 26, 2025 at 1:13 PM
sfb1453.bsky.social
Congratulations to the CIBSS team for this outstanding achievement! So well deserved!!! 🎉👏👏
cibss.bsky.social CIBSS – Centre for Integrative Biological Signalling Studies @cibss.bsky.social · May 22
We are thrilled to have just found out: CIBSS has secured continued funding under the #ExcellenceStrategy! This major boost will enable us to accelerate our research into biological signalling and lay the groundwork for next-generation insights from 2026 to 2032!
May 26, 2025 at 12:26 PM
Reposted by SFB 1453 NephGen
cpattaro.bsky.social
Wondering whether you should read the great kidney disease genetic scorecard paper by @hongbo919.bsky.social @ksusztak.bsky.social on 2.2Mio people?
Here 👇 rdcu.be/eejuB Matthias Wuttke at @sfb1453.bsky.social and I report some highlights for you (and recommend reading the original work) #nephgen
March 24, 2025 at 3:22 PM
Reposted by SFB 1453 NephGen
grosselab.bsky.social
please re-post! we are looking for a PhD candidate:
www.uniklinik-freiburg.de/en/career/jo...
March 6, 2025 at 9:22 AM
sfb1453.bsky.social
Today is #WorldKidneyDay! #MedSky #NephSky #StandUpforScience
March 13, 2025 at 9:36 AM
sfb1453.bsky.social
#RareDiseaseDay #NephSky #MedSky
February 28, 2025 at 2:23 PM
Reposted by SFB 1453 NephGen
sebpreissl.bsky.social
🚨2 fully funded postdoc positions for 6 years 🚨

Are you interested in gene regulation, cardiovascular diseases or aging? Join our team in beautiful Graz, Austria!

Postdoc in Bioinformatics 🖥️
tinyurl.com/3ufv767b

Postdoc in functional genomics and models (e.g. organoids) 🧪
tinyurl.com/4ucahvzn
February 25, 2025 at 7:10 AM
Reposted by SFB 1453 NephGen
uniklinik-fr.bsky.social
Freiburger Forschende zeigen, wie seltene „Nonstop-Mutationen“ die Proteinbildung stören und die Entstehung von #Nierenkrebs fördern können. Erkenntnisse bieten Potenzial für bessere Diagnosen und Therapien.

Link zur Studie: t1p.de/ytfs3

#Medizin #Forschung
February 14, 2025 at 12:47 PM
Reposted by SFB 1453 NephGen
commsbio.nature.com
This study challenges the idea that KDM5D in male cells functions equivalently to the second KDM5C allele in female cells, implicating an interplay between KDM5C mutation and Y chromosome loss in ccRCC development in men.
@sfb1453.bsky.social

www.nature.com/articles/s42...
KDM5C and KDM5D mutations have different consequences in clear cell renal cell carcinoma cells - Communications Biology
This study challenges the idea that KDM5D in male cells functions equivalently to the second KDM5C allele in female cells and implicates an interplay between KDM5C mutation and Y chromosome loss in cc...
www.nature.com
February 18, 2025 at 10:05 PM
sfb1453.bsky.social
Congratulations to @sfb1453.bsky.social PIs Athina Ganner, Elke Neumann-Haefelin, Ian Frew, and Sven Diedierichs and their teams! 👏👏👏 Nonstop mutations cause loss of renal tumor suppressor proteins VHL and BAP1 and affect multiple stages of protein translation www.science.org/doi/10.1126/...
Nonstop mutations cause loss of renal tumor suppressor proteins VHL and BAP1 and affect multiple stages of protein translation
Extending a protein at its end affects its stability, but also its translation efficiency and even selection of its start.
www.science.org
February 13, 2025 at 8:51 AM
sfb1453.bsky.social
For NephGen every day is International #WomenInScienceDay 🔬👩‍🔬🎉

#WomenInScience #WomenInSTEM #February11
February 11, 2025 at 11:29 AM
Reposted by SFB 1453 NephGen
walenteklab.bsky.social
Join us for the fantastic annual @cshlnews.bsky.social #Xenopus cell & developmental Biology course.
Deadline for application is Jan 31st.

meetings.cshl.edu/courses.aspx...
January 22, 2025 at 11:22 AM
sfb1453.bsky.social
And another brand new publication for @sfb1453.bsky.social: Published by Ian Frew and his group in collaboration with Anna Köttgen, Melanie Börries and Natalie Köhler in @kidneyint.bsky.social 🎉🎉🎉 #NephSky

www.kidney-international.org/article/S008...
DEFINE_ME
www.kidney-international.org
January 10, 2025 at 1:41 PM
sfb1453.bsky.social
What a nice way to start the new year! Check out our article on the influence of rare #genetic variants on human #metabolism in the current issue of Nature Genetics
rdcu.be/d5ov1
Thanks to all collaborators and funders, @dfgpublic.bsky.social
Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits
Nature Genetics - Gene-based rare variant aggregation study with the levels of 1,294 plasma and 1,396 urine metabolites from paired specimens of 4,737 participants reveals graded effects of rare,...
rdcu.be
January 2, 2025 at 3:27 PM