RobertoFeuda
@robertofeuda.bsky.social
Associate Professor at the Univerisity of Bologna. Past Maynooth, Oxford, Caltech, Bristol, Leicester and URF Webpage: https://sites.google.com/view/feudalab/home?authuser=0
Pinned
Monoaminergic neurons share transcriptional identity across Bilaterian animals
The evolutionary conservation of cell types over deep time has long been theorised but remains difficult to demonstrate. Monoaminergic neurons, which produce molecules such as serotonin and dopamine, ...
www.biorxiv.org
A productive month for the lab — between new preprints and papers!
Monoaminergic neurons evo and devo www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Opsin evolution in plankton
academic.oup.com/gbe/article/...
Mosquito Cell Atlas (small contrib.)
www.cell.com/cell/fulltex...
Monoaminergic neurons evo and devo www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Opsin evolution in plankton
academic.oup.com/gbe/article/...
Mosquito Cell Atlas (small contrib.)
www.cell.com/cell/fulltex...
Reposted by RobertoFeuda
In the summer (you can tell by the shirt) I had a fabulous conversation about embryology and stem cells with @nmoris.bsky.social at the Crick Institute. Here's the first part of it.
www.youtube.com/watch?v=3WB0...
www.youtube.com/watch?v=3WB0...
The Creativity of Life: A Conversation with Naomi Moris, Part 1
YouTube video by Marginalia Review of Books
www.youtube.com
November 24, 2025 at 12:54 PM
In the summer (you can tell by the shirt) I had a fabulous conversation about embryology and stem cells with @nmoris.bsky.social at the Crick Institute. Here's the first part of it.
www.youtube.com/watch?v=3WB0...
www.youtube.com/watch?v=3WB0...
Reposted by RobertoFeuda
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature Genetics
Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.
www.nature.com
November 18, 2025 at 12:00 PM
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Reposted by RobertoFeuda
Our study on the role of LTR5HS and SVAs in regulation of human neural crest migration is now published as peer-reviewed paper on @molsystbiol.org!
Congrats to first author brilliant postdoc Laura Deelen, and all the authors involved! @imperialsci.bsky.social
www.embopress.org/doi/full/10....
Congrats to first author brilliant postdoc Laura Deelen, and all the authors involved! @imperialsci.bsky.social
www.embopress.org/doi/full/10....
September 22, 2025 at 11:24 AM
Our study on the role of LTR5HS and SVAs in regulation of human neural crest migration is now published as peer-reviewed paper on @molsystbiol.org!
Congrats to first author brilliant postdoc Laura Deelen, and all the authors involved! @imperialsci.bsky.social
www.embopress.org/doi/full/10....
Congrats to first author brilliant postdoc Laura Deelen, and all the authors involved! @imperialsci.bsky.social
www.embopress.org/doi/full/10....
Reposted by RobertoFeuda
Happy to share Jialin's first publication. She did a great job exploring the transition to land in animals. Co-supervised by the great Jordi Paps and me and in collaboration with Davide Pisani and @phil-donoghue.bsky.social
Nature research paper: Convergent genome evolution shaped the emergence of terrestrial animals
go.nature.com/4i0i61w
go.nature.com/4i0i61w
Convergent genome evolution shaped the emergence of terrestrial animals - Nature
Comparisons of 154 genomes from 21 animal phyla and outgroups have been used to reconstruct ancestral adaptation to life on land across 11 distinct terrestrialization events, revealing strong evidence for convergent genomic evolution across the animal kingdom and recurring periods of terrestrial colonization.
go.nature.com
November 13, 2025 at 3:18 PM
Happy to share Jialin's first publication. She did a great job exploring the transition to land in animals. Co-supervised by the great Jordi Paps and me and in collaboration with Davide Pisani and @phil-donoghue.bsky.social
Reposted by RobertoFeuda
Nature research paper: Convergent genome evolution shaped the emergence of terrestrial animals
go.nature.com/4i0i61w
go.nature.com/4i0i61w
Convergent genome evolution shaped the emergence of terrestrial animals - Nature
Comparisons of 154 genomes from 21 animal phyla and outgroups have been used to reconstruct ancestral adaptation to life on land across 11 distinct terrestrialization events, revealing strong evidence for convergent genomic evolution across the animal kingdom and recurring periods of terrestrial colonization.
go.nature.com
November 13, 2025 at 9:18 AM
Nature research paper: Convergent genome evolution shaped the emergence of terrestrial animals
go.nature.com/4i0i61w
go.nature.com/4i0i61w
Reposted by RobertoFeuda
November 13, 2025 at 7:23 PM
Reposted by RobertoFeuda
Working in a biomed institute, its natural to think about health & medical impact of dev bio but there's more to dev bio
Agriculture is dev bio (plant growth, livestock breeding)
And dev bio is important to understand environment & climate impact. See e.g:
journals.biologists.com/dev/article/...
Agriculture is dev bio (plant growth, livestock breeding)
And dev bio is important to understand environment & climate impact. See e.g:
journals.biologists.com/dev/article/...
In preprints: multiomics of low temperature acclimation in the era of intensifying temperature fluctuations
In a warming world, all life forms – endotherms and ectotherms alike – are finding their homeostasis being challenged. The environmental change is challenging at all stages of life. How different orga...
journals.biologists.com
November 5, 2025 at 12:33 PM
Working in a biomed institute, its natural to think about health & medical impact of dev bio but there's more to dev bio
Agriculture is dev bio (plant growth, livestock breeding)
And dev bio is important to understand environment & climate impact. See e.g:
journals.biologists.com/dev/article/...
Agriculture is dev bio (plant growth, livestock breeding)
And dev bio is important to understand environment & climate impact. See e.g:
journals.biologists.com/dev/article/...
A productive month for the lab — between new preprints and papers!
Monoaminergic neurons evo and devo www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Opsin evolution in plankton
academic.oup.com/gbe/article/...
Mosquito Cell Atlas (small contrib.)
www.cell.com/cell/fulltex...
Monoaminergic neurons evo and devo www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Opsin evolution in plankton
academic.oup.com/gbe/article/...
Mosquito Cell Atlas (small contrib.)
www.cell.com/cell/fulltex...
Monoaminergic neurons share transcriptional identity across Bilaterian animals
The evolutionary conservation of cell types over deep time has long been theorised but remains difficult to demonstrate. Monoaminergic neurons, which produce molecules such as serotonin and dopamine, ...
www.biorxiv.org
November 4, 2025 at 1:43 PM
A productive month for the lab — between new preprints and papers!
Monoaminergic neurons evo and devo www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Opsin evolution in plankton
academic.oup.com/gbe/article/...
Mosquito Cell Atlas (small contrib.)
www.cell.com/cell/fulltex...
Monoaminergic neurons evo and devo www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Opsin evolution in plankton
academic.oup.com/gbe/article/...
Mosquito Cell Atlas (small contrib.)
www.cell.com/cell/fulltex...
Reposted by RobertoFeuda
Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female
Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell
types and widespread co-expres...
www.cell.com
October 30, 2025 at 4:05 PM
Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
New preprint out! Evolutionarily conserved transcriptional regulators control monoaminergic neuron development.
We uncover how ancient regulatory programs orchestrate the neurons that produce serotonin and dopamine across 550 million years of evolution.
doi.org/10.1101/2025...
We uncover how ancient regulatory programs orchestrate the neurons that produce serotonin and dopamine across 550 million years of evolution.
doi.org/10.1101/2025...
Evolutionarily conserved transcriptional regulators control monoaminergic neuron development
To what extent conserved developmental programs specify homologous cell types is a central question in biology. Here, we address this by focusing on reconstructing monoaminergic neuron development in ...
doi.org
October 30, 2025 at 9:42 AM
New preprint out! Evolutionarily conserved transcriptional regulators control monoaminergic neuron development.
We uncover how ancient regulatory programs orchestrate the neurons that produce serotonin and dopamine across 550 million years of evolution.
doi.org/10.1101/2025...
We uncover how ancient regulatory programs orchestrate the neurons that produce serotonin and dopamine across 550 million years of evolution.
doi.org/10.1101/2025...
Reposted by RobertoFeuda
Come join the #LondonEvoDevo network half day meeting, hosted at @ucl.ac.uk on Friday November 7th, 2025. Submit your abstract by Oct 27th (or your interest in joining) here: forms.gle/TRbdrCkQTcY2.... Friendly vibes and free registration. More info here: londonevodevo.co.uk.
LondonEvoDevo
meeting's website
londonevodevo.co.uk
October 20, 2025 at 1:42 PM
Come join the #LondonEvoDevo network half day meeting, hosted at @ucl.ac.uk on Friday November 7th, 2025. Submit your abstract by Oct 27th (or your interest in joining) here: forms.gle/TRbdrCkQTcY2.... Friendly vibes and free registration. More info here: londonevodevo.co.uk.
We have a fully funded PhD to study mosquito vision — combining single-cell genomics, evolutionary genomics & high-resolution imaging.
Discover how these tiny hunters see the world.
RP, apply and contact me if interested! warwick.ac.uk/fac/cross_fa...
Discover how these tiny hunters see the world.
RP, apply and contact me if interested! warwick.ac.uk/fac/cross_fa...
Dr Roberto Feuda
Dr Roberto Feuda
warwick.ac.uk
October 17, 2025 at 9:56 AM
We have a fully funded PhD to study mosquito vision — combining single-cell genomics, evolutionary genomics & high-resolution imaging.
Discover how these tiny hunters see the world.
RP, apply and contact me if interested! warwick.ac.uk/fac/cross_fa...
Discover how these tiny hunters see the world.
RP, apply and contact me if interested! warwick.ac.uk/fac/cross_fa...
Reposted by RobertoFeuda
The version of record of our paper on the emergence of metachronal waves in the #platynereis larval ciliary band is now out. Together with Rebecca Poon and Kirsty Wan @micromotility.bsky.social
https://www.science.org/doi/10.1126/sciadv.adw4067
funded by
@ERC_Research @wellcometrust @bbsrc
https://www.science.org/doi/10.1126/sciadv.adw4067
funded by
@ERC_Research @wellcometrust @bbsrc
October 16, 2025 at 11:48 AM
The version of record of our paper on the emergence of metachronal waves in the #platynereis larval ciliary band is now out. Together with Rebecca Poon and Kirsty Wan @micromotility.bsky.social
https://www.science.org/doi/10.1126/sciadv.adw4067
funded by
@ERC_Research @wellcometrust @bbsrc
https://www.science.org/doi/10.1126/sciadv.adw4067
funded by
@ERC_Research @wellcometrust @bbsrc
Reposted by RobertoFeuda
We are happy to share our latest work in @nature.com . We study the genomic and cellular basis of facultative symbiosis in Oculina patagonica - a Mediterranean coral remarkable for its ability to survive long periods without algal symbionts. Led by Shani Levy and @xgrau.bsky.social
rdcu.be/eLbaZ
rdcu.be/eLbaZ
October 15, 2025 at 7:58 PM
We are happy to share our latest work in @nature.com . We study the genomic and cellular basis of facultative symbiosis in Oculina patagonica - a Mediterranean coral remarkable for its ability to survive long periods without algal symbionts. Led by Shani Levy and @xgrau.bsky.social
rdcu.be/eLbaZ
rdcu.be/eLbaZ
Interested in joining my lab to study the evolution and development of monoaminergic neurons?
You can now apply for the Giuseppe Levi Post-Doc Fellowship (2 years, Neurobiology, EU citizens).
Deadline: 10 Nov 2025 – 18:00
For more info selezionionline.lincei.it and email me!
You can now apply for the Giuseppe Levi Post-Doc Fellowship (2 years, Neurobiology, EU citizens).
Deadline: 10 Nov 2025 – 18:00
For more info selezionionline.lincei.it and email me!
Online Applications – Accademia Nazionale dei Lincei
- Home
Online Applications – Accademia Nazionale dei Lincei
selezionionline.lincei.it
October 14, 2025 at 10:43 AM
Interested in joining my lab to study the evolution and development of monoaminergic neurons?
You can now apply for the Giuseppe Levi Post-Doc Fellowship (2 years, Neurobiology, EU citizens).
Deadline: 10 Nov 2025 – 18:00
For more info selezionionline.lincei.it and email me!
You can now apply for the Giuseppe Levi Post-Doc Fellowship (2 years, Neurobiology, EU citizens).
Deadline: 10 Nov 2025 – 18:00
For more info selezionionline.lincei.it and email me!
Reposted by RobertoFeuda
Thrilled to share that the lab has been awarded a @wellcometrust.bsky.social Discovery Award to keep exploring the evolution of 6-methyladenine #6mA in Eukaryotes. We'll open postdoc (3️⃣) and tech (1️⃣) positions to start in 2026, please share with candidates or reach out if you’d like to join us.
October 8, 2025 at 12:17 PM
Thrilled to share that the lab has been awarded a @wellcometrust.bsky.social Discovery Award to keep exploring the evolution of 6-methyladenine #6mA in Eukaryotes. We'll open postdoc (3️⃣) and tech (1️⃣) positions to start in 2026, please share with candidates or reach out if you’d like to join us.
Reposted by RobertoFeuda
The @crick.ac.uk is recruiting Early Career Group Leaders
- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology
Deadline 27 Nov
www.crick.ac.uk/careers-stud...
- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology
Deadline 27 Nov
www.crick.ac.uk/careers-stud...
Early career group leaders
We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.
www.crick.ac.uk
October 10, 2025 at 8:20 AM
The @crick.ac.uk is recruiting Early Career Group Leaders
- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology
Deadline 27 Nov
www.crick.ac.uk/careers-stud...
- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology
Deadline 27 Nov
www.crick.ac.uk/careers-stud...
Our latest: combining single-cell RNA-seq from 16 species and HCR validation, we show that monoaminergic neurons share a conserved transcriptional identity across Bilateria. In contrast, we find no evidence for this program in non-bilaterian metazoans. www.biorxiv.org/content/10.1...
Monoaminergic neurons share transcriptional identity across Bilaterian animals
The evolutionary conservation of cell types over deep time has long been theorised but remains difficult to demonstrate. Monoaminergic neurons, which produce molecules such as serotonin and dopamine, ...
www.biorxiv.org
October 10, 2025 at 9:43 PM
Our latest: combining single-cell RNA-seq from 16 species and HCR validation, we show that monoaminergic neurons share a conserved transcriptional identity across Bilateria. In contrast, we find no evidence for this program in non-bilaterian metazoans. www.biorxiv.org/content/10.1...
Reposted by RobertoFeuda
I adored writing this piece. It brings together several of the things preoccupying me right now, like chromatin organization and gene regulation. There's so much more to be said on that. Also, these marine critters look gorgeous.
www.quantamagazine.org/loops-of-dna...
www.quantamagazine.org/loops-of-dna...
Loops of DNA Equipped Ancient Life To Become Complex | Quanta Magazine
New work shows that physical folding of the genome to control genes located far away may have been an early evolutionary development.
www.quantamagazine.org
October 8, 2025 at 2:21 PM
I adored writing this piece. It brings together several of the things preoccupying me right now, like chromatin organization and gene regulation. There's so much more to be said on that. Also, these marine critters look gorgeous.
www.quantamagazine.org/loops-of-dna...
www.quantamagazine.org/loops-of-dna...
Reposted by RobertoFeuda
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Flagellar gliding in choanoflagellates
Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates,
the closest relatives of animals. Under mild confinement, choanoflagellate move over
surfaces without cell deformat...
www.cell.com
September 9, 2025 at 6:12 PM
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Our latest: We optimized SPLiT-Seq for insect brains!
Check out our new protocol in Methods in Molecular Biology—tailored single-cell transcriptomics for insect neuroscience link.springer.com/protocol/10....
Check out our new protocol in Methods in Molecular Biology—tailored single-cell transcriptomics for insect neuroscience link.springer.com/protocol/10....
An Optimized SPLiT-Seq Protocol for Insects
Single-cell RNA-sequencing revolutionized our approach of transcriptomic studies, enabling to analyze gene expression across cell type in a tissue. Here we introduce an optimized cell dissociation and...
link.springer.com
August 22, 2025 at 4:30 PM
Our latest: We optimized SPLiT-Seq for insect brains!
Check out our new protocol in Methods in Molecular Biology—tailored single-cell transcriptomics for insect neuroscience link.springer.com/protocol/10....
Check out our new protocol in Methods in Molecular Biology—tailored single-cell transcriptomics for insect neuroscience link.springer.com/protocol/10....
Reposted by RobertoFeuda
After nearly twenty years in the making, our attempt at understanding what makes the chaetognath phylum so unique has finally been published! www.nature.com/articles/s41...
with #LauraPiovani @dariagavr.bsky.social @alexdemendoza.bsky.social @chemamd.bsky.social and others /1
with #LauraPiovani @dariagavr.bsky.social @alexdemendoza.bsky.social @chemamd.bsky.social and others /1
The genomic origin of the unique chaetognath body plan - Nature
Genomic, single-cell transcriptomic and epigenetic analyses show that chaetognaths, following extensive gene loss in the gnathiferan lineage, relied on newly evolved genes and lineage-specific tandem ...
www.nature.com
August 13, 2025 at 4:38 PM
After nearly twenty years in the making, our attempt at understanding what makes the chaetognath phylum so unique has finally been published! www.nature.com/articles/s41...
with #LauraPiovani @dariagavr.bsky.social @alexdemendoza.bsky.social @chemamd.bsky.social and others /1
with #LauraPiovani @dariagavr.bsky.social @alexdemendoza.bsky.social @chemamd.bsky.social and others /1
Reposted by RobertoFeuda
A Summer reading recommendation: new primer in @dev-journal.bsky.social explains how dynamical systems theory unlocks the logic of developmental patterning
Everything from bistable switches & oscillators to phase portraits & more with Python code to explore
journals.biologists.com/dev/article/...
Everything from bistable switches & oscillators to phase portraits & more with Python code to explore
journals.biologists.com/dev/article/...
From genes to patterns: five key dynamical systems concepts to decode developmental regulatory mechanisms
Summary: Dynamical systems theory provides a powerful quantitative and intuitive framework to understand developmental processes. This Primer brings key concepts of this framework to the ever-growing ...
journals.biologists.com
August 4, 2025 at 8:44 AM
A Summer reading recommendation: new primer in @dev-journal.bsky.social explains how dynamical systems theory unlocks the logic of developmental patterning
Everything from bistable switches & oscillators to phase portraits & more with Python code to explore
journals.biologists.com/dev/article/...
Everything from bistable switches & oscillators to phase portraits & more with Python code to explore
journals.biologists.com/dev/article/...
Reposted by RobertoFeuda
Happy to see our latest work out in @molbioevol.bsky.social. We revisit the evolution of 5-methylcytosine across neglected eukaryotic supergroups, establishing an ancestral repressive role silencing genome invaders, both transposons and viral elements👾: academic.oup.com/mbe/advance-... 🧵 1/7
Repressive cytosine methylation is a marker of viral gene transfer across divergent eukaryotes
Abstract. Cytosine DNA methylation patterns vary widely across eukaryotes, with its ancestral roles being understood to have included both transposable ele
academic.oup.com
July 28, 2025 at 10:03 AM
Happy to see our latest work out in @molbioevol.bsky.social. We revisit the evolution of 5-methylcytosine across neglected eukaryotic supergroups, establishing an ancestral repressive role silencing genome invaders, both transposons and viral elements👾: academic.oup.com/mbe/advance-... 🧵 1/7
Reposted by RobertoFeuda
✨Animal evolution fans, rejoice! CRISPR-Cas9 is now in Corallochytrium ready to unlock secrets of animal origins! 🔬Led by @patriciasuarez.bsky.social & @sebasn1.bsky.social
royalsocietypublishing.org/doi/10.1098/... @royalsociety.org @ibe-barcelona.bsky.social#holozoans #ProtistsonSky
royalsocietypublishing.org/doi/10.1098/... @royalsociety.org @ibe-barcelona.bsky.social#holozoans #ProtistsonSky
CRISPR-Cas9 genome editing in Corallochytrium limacisporum,a key species for understanding animal origins | Open Biology
Microbial holozoans are the closest unicellular relatives of animals. They share a
substantial gene repertoire with animals and exhibit complex life cycles. Studying
these organisms is crucial for und...
royalsocietypublishing.org
July 28, 2025 at 7:35 AM
✨Animal evolution fans, rejoice! CRISPR-Cas9 is now in Corallochytrium ready to unlock secrets of animal origins! 🔬Led by @patriciasuarez.bsky.social & @sebasn1.bsky.social
royalsocietypublishing.org/doi/10.1098/... @royalsociety.org @ibe-barcelona.bsky.social#holozoans #ProtistsonSky
royalsocietypublishing.org/doi/10.1098/... @royalsociety.org @ibe-barcelona.bsky.social#holozoans #ProtistsonSky