🧬Jacob L Steenwyk
@jlsteenwyk.bsky.social
UC-Berkeley Postdoc🐻, Edison Scientific Consultant👨🏽💻, Evomics Workshop Codirector🧬
prev Vanderbilt PhD, FutureHouse, Latch, MantleBio (acquired)
🌲 https://linktr.ee/jlsteenwyk
📍 https://jlsteenwyk.com/
prev Vanderbilt PhD, FutureHouse, Latch, MantleBio (acquired)
🌲 https://linktr.ee/jlsteenwyk
📍 https://jlsteenwyk.com/
Pinned
🧬Jacob L Steenwyk
@jlsteenwyk.bsky.social
· Nov 10
Genomics, evolution, and more starter pack!
Help build community with this starter pack.
This list is currently incomplete. Want to be included? Reply and I will remedy that!
go.bsky.app/JjvzkWU
Help build community with this starter pack.
This list is currently incomplete. Want to be included? Reply and I will remedy that!
go.bsky.app/JjvzkWU
Art that is human-made feels like a beautiful act of resistance against AI. Lux by Rosalia is a great example
I anticipate we will see more and more of this — and human-made, much like hand-made goods, will come at a premium
I anticipate we will see more and more of this — and human-made, much like hand-made goods, will come at a premium
December 2, 2025 at 5:50 PM
Art that is human-made feels like a beautiful act of resistance against AI. Lux by Rosalia is a great example
I anticipate we will see more and more of this — and human-made, much like hand-made goods, will come at a premium
I anticipate we will see more and more of this — and human-made, much like hand-made goods, will come at a premium
Wikipedia reminds me that millions of strangers collectively built one of the greatest knowledge resources in history -- and it is free.
Faith in humanity stays strong
Faith in humanity stays strong
December 2, 2025 at 4:28 AM
Wikipedia reminds me that millions of strangers collectively built one of the greatest knowledge resources in history -- and it is free.
Faith in humanity stays strong
Faith in humanity stays strong
I hope everyone is having a restful and happy holiday 😊
November 29, 2025 at 3:52 AM
I hope everyone is having a restful and happy holiday 😊
Things are coming up roses
November 24, 2025 at 4:40 PM
Things are coming up roses
Fluorescent microscopy is beautiful🔬✨
People who are pushing the envelope will not only uncover new biology, but captivate (and entice!) new generations of brilliant minds to love biology the same way we do
People who are pushing the envelope will not only uncover new biology, but captivate (and entice!) new generations of brilliant minds to love biology the same way we do
November 23, 2025 at 9:02 PM
Fluorescent microscopy is beautiful🔬✨
People who are pushing the envelope will not only uncover new biology, but captivate (and entice!) new generations of brilliant minds to love biology the same way we do
People who are pushing the envelope will not only uncover new biology, but captivate (and entice!) new generations of brilliant minds to love biology the same way we do
I'm taking recommendations for the type of content you'd like to see on my Substack. I feature weekly newsletters about what is happening in BioAI (eg, research advances) and what is happening in Biotech (eg, acquisitions, mergers)
Please feel free to DM me if there's something you'd like to see!
Please feel free to DM me if there's something you'd like to see!
November 23, 2025 at 8:54 PM
I'm taking recommendations for the type of content you'd like to see on my Substack. I feature weekly newsletters about what is happening in BioAI (eg, research advances) and what is happening in Biotech (eg, acquisitions, mergers)
Please feel free to DM me if there's something you'd like to see!
Please feel free to DM me if there's something you'd like to see!
A highlight of my career was when one of my thesis chapters was highlighted on the #SciShow by @hankgreen.bsky.social. I was in my 2nd or 3rd year of my PhD
November 22, 2025 at 4:45 PM
A highlight of my career was when one of my thesis chapters was highlighted on the #SciShow by @hankgreen.bsky.social. I was in my 2nd or 3rd year of my PhD
I'm way too into keyboards 😆
November 22, 2025 at 6:04 AM
I'm way too into keyboards 😆
Reposted by 🧬Jacob L Steenwyk
Did the first animal look like a sponge or a comb jelly? The debate continues. Check out the article from MCB's Nicole King and postdoc Jacob Steenwyk @jlsteenwyk.bsky.social:
news.berkeley.edu/2025/11/19/d...
news.berkeley.edu/2025/11/19/d...
Did the first animal look like a sponge or a comb jelly? The debate continues. - Berkeley News
Two years ago, a novel analysis by UC Berkeley researchers pointed to comb jellies as the root of the animal tree of life. Another Berkeley group now says it’s sponges.
news.berkeley.edu
November 21, 2025 at 1:54 AM
Did the first animal look like a sponge or a comb jelly? The debate continues. Check out the article from MCB's Nicole King and postdoc Jacob Steenwyk @jlsteenwyk.bsky.social:
news.berkeley.edu/2025/11/19/d...
news.berkeley.edu/2025/11/19/d...
There's been an uptick in visitors to my website jlsteenwyk.com. If there is a type of content that you would find helpful (e.g., more bioinformatics tutorials, etc), please let me know!
My website has many purposes including serving as a resource for the community!
My website has many purposes including serving as a resource for the community!
Jacob L. Steenwyk | Evolutionary Bioinformatics & Comparative Genomics
Evolutionary biologist and bioinformatician Jacob L. Steenwyk leads comparative genomics, fungal pathogenesis research, and open-source software development.
jlsteenwyk.com
November 20, 2025 at 5:30 PM
There's been an uptick in visitors to my website jlsteenwyk.com. If there is a type of content that you would find helpful (e.g., more bioinformatics tutorials, etc), please let me know!
My website has many purposes including serving as a resource for the community!
My website has many purposes including serving as a resource for the community!
Prompt: "Can you rotate the clade encompassing A, B, C and D"
1st image is the original, the 2nd image is after 'rotation'
They are the same. The LLM was unable to rotate the clade.
Frontier Labs, we can get this right - I feel very strongly about our ability to do so!
bsky.app/profile/jlst...
1st image is the original, the 2nd image is after 'rotation'
They are the same. The LLM was unable to rotate the clade.
Frontier Labs, we can get this right - I feel very strongly about our ability to do so!
bsky.app/profile/jlst...
November 20, 2025 at 5:27 PM
Prompt: "Can you rotate the clade encompassing A, B, C and D"
1st image is the original, the 2nd image is after 'rotation'
They are the same. The LLM was unable to rotate the clade.
Frontier Labs, we can get this right - I feel very strongly about our ability to do so!
bsky.app/profile/jlst...
1st image is the original, the 2nd image is after 'rotation'
They are the same. The LLM was unable to rotate the clade.
Frontier Labs, we can get this right - I feel very strongly about our ability to do so!
bsky.app/profile/jlst...
Wow - what a location! This looks awesome!
bsky.app/profile/erik...
bsky.app/profile/erik...
With #eseb2025 coming to a close, it is time to start making plans for 2026. Interested in the interface of evolution 🧬 and ecology 🌳? Come to our #ExE conference hosted by @uniexecec.bsky.social in beautiful #Cornwall. Leave your email address at tinyurl.com/EvolxEcol to join our mailing list!
November 20, 2025 at 5:14 PM
Wow - what a location! This looks awesome!
bsky.app/profile/erik...
bsky.app/profile/erik...
Companies building frontier LLMs, please let me help you teach your models how to interpret evolution
These are *so* wrong, but I know we can get it right.
prompt: "create an image of a phylogenetic tree with the following topology (((A,B),(C,D)),E);"
These are *so* wrong, but I know we can get it right.
prompt: "create an image of a phylogenetic tree with the following topology (((A,B),(C,D)),E);"
November 20, 2025 at 5:42 AM
Companies building frontier LLMs, please let me help you teach your models how to interpret evolution
These are *so* wrong, but I know we can get it right.
prompt: "create an image of a phylogenetic tree with the following topology (((A,B),(C,D)),E);"
These are *so* wrong, but I know we can get it right.
prompt: "create an image of a phylogenetic tree with the following topology (((A,B),(C,D)),E);"
Reposted by 🧬Jacob L Steenwyk
Hey folks, we (the School of Life Sciences at Arizona State University) are looking for an Assistant Teaching Professor in microbiology and immunology. Please pass this on to anyone you think might be interested, or check it out if you are interested yourself!
apply.interfolio.com/176994
apply.interfolio.com/176994
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
November 19, 2025 at 4:59 PM
Hey folks, we (the School of Life Sciences at Arizona State University) are looking for an Assistant Teaching Professor in microbiology and immunology. Please pass this on to anyone you think might be interested, or check it out if you are interested yourself!
apply.interfolio.com/176994
apply.interfolio.com/176994
"Project Prometheus aims to build AI systems for engineering and manufacturing across several industries, including computers, automobiles, and spacecraft"
www.eweek.com/news/jeff-be...
www.eweek.com/news/jeff-be...
Jeff Bezos Unveils AI Startup Project Prometheus | eWEEK
The company begins life with $6.2 billion in funding — an extraordinary sum for an early-stage startup.
www.eweek.com
November 17, 2025 at 9:36 PM
"Project Prometheus aims to build AI systems for engineering and manufacturing across several industries, including computers, automobiles, and spacecraft"
www.eweek.com/news/jeff-be...
www.eweek.com/news/jeff-be...
Over a century ago, Hannah Höch gifted us with the Dada piece titled "Cut with the Kitchen Knife Dada Through the Last Weimar Beer-Belly Cultural Epoch of Germany" (1919-20).
imo, this collage shreds meaning, mocks certainty, and still feels more honest than most timelines today. Awesome piece
imo, this collage shreds meaning, mocks certainty, and still feels more honest than most timelines today. Awesome piece
November 17, 2025 at 3:43 AM
Over a century ago, Hannah Höch gifted us with the Dada piece titled "Cut with the Kitchen Knife Dada Through the Last Weimar Beer-Belly Cultural Epoch of Germany" (1919-20).
imo, this collage shreds meaning, mocks certainty, and still feels more honest than most timelines today. Awesome piece
imo, this collage shreds meaning, mocks certainty, and still feels more honest than most timelines today. Awesome piece
today has been a wonderful day of rot
November 17, 2025 at 3:15 AM
today has been a wonderful day of rot
Perhaps I should clarify that I speak for myself and can't speak on behalf of my social media-free advisor.
So please consider this my personal stance :)
bsky.app/profile/jlst...
So please consider this my personal stance :)
bsky.app/profile/jlst...
Thus, we don't take a strong stance. We only report that integrative phylogenomics convergences on one of the two topologies
I hope this helps clarify our stance and I'm happy to address any other questions you (& others) may have :)
I hope this helps clarify our stance and I'm happy to address any other questions you (& others) may have :)
November 16, 2025 at 4:40 PM
Perhaps I should clarify that I speak for myself and can't speak on behalf of my social media-free advisor.
So please consider this my personal stance :)
bsky.app/profile/jlst...
So please consider this my personal stance :)
bsky.app/profile/jlst...
Cherry chip #mushrooms 🍒🍄
This reddish-orange #mushroom gets its name from a #cherry-like coloration🔴 and for being found in #wood chips🌳
Awesome find in the backyard!
This reddish-orange #mushroom gets its name from a #cherry-like coloration🔴 and for being found in #wood chips🌳
Awesome find in the backyard!
November 16, 2025 at 1:20 AM
Cherry chip #mushrooms 🍒🍄
This reddish-orange #mushroom gets its name from a #cherry-like coloration🔴 and for being found in #wood chips🌳
Awesome find in the backyard!
This reddish-orange #mushroom gets its name from a #cherry-like coloration🔴 and for being found in #wood chips🌳
Awesome find in the backyard!
Folks have been super kind regarding this manuscript
It is such a contentious topic that I wondered if letting this project go beyond the four walls of the lab was a personal/emotional mistake
But no - it wasn't
People are chill. People are nice. This community rules 🤘
bsky.app/profile/jlst...
It is such a contentious topic that I wondered if letting this project go beyond the four walls of the lab was a personal/emotional mistake
But no - it wasn't
People are chill. People are nice. This community rules 🤘
bsky.app/profile/jlst...
NEW pub in @science.org 🥳
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
November 15, 2025 at 10:13 PM
Folks have been super kind regarding this manuscript
It is such a contentious topic that I wondered if letting this project go beyond the four walls of the lab was a personal/emotional mistake
But no - it wasn't
People are chill. People are nice. This community rules 🤘
bsky.app/profile/jlst...
It is such a contentious topic that I wondered if letting this project go beyond the four walls of the lab was a personal/emotional mistake
But no - it wasn't
People are chill. People are nice. This community rules 🤘
bsky.app/profile/jlst...
Today is the last day to register!
Please consider doing so - it is going to be a fun one!
Register here: evomics.org/apply-worksh...
bsky.app/profile/jlst...
Please consider doing so - it is going to be a fun one!
Register here: evomics.org/apply-worksh...
bsky.app/profile/jlst...
November 15, 2025 at 8:15 PM
Today is the last day to register!
Please consider doing so - it is going to be a fun one!
Register here: evomics.org/apply-worksh...
bsky.app/profile/jlst...
Please consider doing so - it is going to be a fun one!
Register here: evomics.org/apply-worksh...
bsky.app/profile/jlst...
I decided to join in on the fun and write a popular science-y article about the recent manuscript. It is available on the @genomelybio.bsky.social Substack
Subscribe for free :D
genomely.substack.com/p/what-was-t...
bsky.app/profile/jlst...
Subscribe for free :D
genomely.substack.com/p/what-was-t...
bsky.app/profile/jlst...
November 15, 2025 at 6:58 PM
I decided to join in on the fun and write a popular science-y article about the recent manuscript. It is available on the @genomelybio.bsky.social Substack
Subscribe for free :D
genomely.substack.com/p/what-was-t...
bsky.app/profile/jlst...
Subscribe for free :D
genomely.substack.com/p/what-was-t...
bsky.app/profile/jlst...
I really appreciated this popular science article covering our recent manuscript — big shout-out to @jakecurrie.bsky.social, thank you so much for taking the time to share your writing!
nautil.us/fierce-debat... bsky.app/profile/jlst...
nautil.us/fierce-debat... bsky.app/profile/jlst...
November 15, 2025 at 5:05 PM
I really appreciated this popular science article covering our recent manuscript — big shout-out to @jakecurrie.bsky.social, thank you so much for taking the time to share your writing!
nautil.us/fierce-debat... bsky.app/profile/jlst...
nautil.us/fierce-debat... bsky.app/profile/jlst...
The number of free subscriptions to @genomelybio.bsky.social substack has been steadily growing.
Super thankful folks find my BioAI and biotech development weeklys helpful. Looking forward to writing more deep dives in the future.
Appreciate you :)
open.substack.com/pub/genomely...
Super thankful folks find my BioAI and biotech development weeklys helpful. Looking forward to writing more deep dives in the future.
Appreciate you :)
open.substack.com/pub/genomely...
Genomely | 🧬Jacob L Steenwyk | Substack
Where Genomics and Evolution Converge. Click to read Genomely, by 🧬Jacob L Steenwyk, a Substack publication with hundreds of subscribers.
open.substack.com
November 15, 2025 at 3:24 AM
The number of free subscriptions to @genomelybio.bsky.social substack has been steadily growing.
Super thankful folks find my BioAI and biotech development weeklys helpful. Looking forward to writing more deep dives in the future.
Appreciate you :)
open.substack.com/pub/genomely...
Super thankful folks find my BioAI and biotech development weeklys helpful. Looking forward to writing more deep dives in the future.
Appreciate you :)
open.substack.com/pub/genomely...