Victor Puelles
puellesv.bsky.social
Victor Puelles
@puellesv.bsky.social
Reposted by Victor Puelles
Nature research paper: Oxygen-free metabolism in the bird inner retina supported by the pecten

go.nature.com/3Lol4Be
Oxygen-free metabolism in the bird inner retina supported by the pecten - Nature
While the photoreceptor outer segments in the bird outer retina have access to oxygen, the inner retina operates under chronic anoxia, supported by anaerobic glycolysis in the retinal neurons.
go.nature.com
January 23, 2026 at 3:51 PM
Reposted by Victor Puelles
🤖🧬 New biomedical MCP server added to the registry:
Open Targets Platform MCP
Check it out at https://biocontext.ai/registry/opentargets/open-targets-platform-mcp
January 20, 2026 at 6:46 PM
Reposted by Victor Puelles
#FluorescenceFriday

Proud of our the last paper @cellcommlab.bsky.social & 1st one of @jboixcampos.bsky.social

We continue to study #CellMigration & how cells decide where to go: ↖️↗️⬇️?

(movie of the actin #cytoskeleton)

Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
January 9, 2026 at 4:23 PM
Reposted by Victor Puelles
Our KAW research grant focuses on uncovering novel drivers of mucosal healing by leveraging unique IBD cohorts and novel technologies to map cell–microbiota interactions, complemented by advanced non-animal models like human organoids

Check the note 👇🏼

kaw.wallenberg.org/en/research/... #Hashtag
Promoting healing to cure intestinal autoimmunity | Knut and Alice Wallenberg Foundation
Immunosuppressive drugs are currently the main therapeutic option for treating inflammatory bowel disease (IBD). However, fewer than half of patients achieve sustained benefit, and these treatments ca...
kaw.wallenberg.org
January 9, 2026 at 1:15 AM
Reposted by Victor Puelles
Reposted by Victor Puelles
Do you know how far phototoxicity can hinder your experiments?🤔 @mariodelr.bsky.social and @gomez-mariscal.bsky.social have just published their work on #PhotoFiTT in @natcomms.nature.com where they explain how to quantitatively measure it in live-cell imaging.⚡🧫🔬

Read more at: shorturl.at/ly9Zn
December 15, 2025 at 3:38 PM
Reposted by Victor Puelles
🚨🔬🤖🚀 #PhotoFiTT is out! With @guijacquemet.bsky.social's & @microbematos.bsky.social's labs, we launched a new phototoxicity measurement for live microscopy using cell clocks⏱️. By rockstars @mariodelr.bsky.social @gomez-mariscal.bsky.social et al! AI-powered + label-free
doi.org/10.1038/s414...
December 15, 2025 at 3:22 PM
Reposted by Victor Puelles
It’s FINALLY out! 🎉🚀 We have been working on PhotoFiTT for a long time, and it’s now published, introducing a quantitative framework to measure phototoxicity and optimise live-cell microscopy experiments. So excited to finally share the last version! 🔬✨ #PhotoFiTT doi.org/10.1038/s414...
December 15, 2025 at 2:58 PM
Reposted by Victor Puelles
🚨Amazing news for a cloudy Monday!🌩️😎 I'm extremely happy to share that our last adventure is finally out!🚀🎉Phototoxicity fitness time trial (#PhotoFiTT) - a quantitative framework for assessing phototoxicity in live-cell microscopy experiments 🔬❤️‍🔥⚡️ doi.org/10.1038/s414...
December 15, 2025 at 2:58 PM
Reposted by Victor Puelles
AI holds huge promise for life science research. But unreliable answers currently limit its impact.

@juliosaezrod.bsky.social, Head of Research at EMBL-EBI, discusses how Model Context Protocol (MCP) servers are helping to change this.

www.ebi.ac.uk/about/news/p...
🧬💻
Connecting AI to biology: Model Context Protocol
Julio Saez-Rodriguez discusses how MCP servers are helping AI connect to life science databases, making AI a more reproducible tool for research.
www.ebi.ac.uk
December 2, 2025 at 11:26 AM
Reposted by Victor Puelles
Doctoral (PhD) Position – Spatial Transcriptomics, Bioinformatics & Mucosal Immunology

📍 Karolinska Institutet, Sweden

🗓️ Deadline: Dec 10, 2025

kidoktorand.varbi.com/what:job/job...

#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
November 29, 2025 at 4:15 PM
Reposted by Victor Puelles
Truly happy to host Victor Puelles in Marburg today, talking about complex tissue analysis across biological scales. Thrilling science and exciting discussions! @puellesv.bsky.social
November 27, 2025 at 6:39 PM
Reposted by Victor Puelles
Really excited for our November issue, and I feel like I'm starting to get into the groove of writing editorials for nBME (with the help of the team of course!). Please check it out!
November 17, 2025 at 7:39 PM
Reposted by Victor Puelles
I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...
November 13, 2025 at 8:49 PM
Reposted by Victor Puelles
BioContextAI is an open-source initiative for creating agentic biomedical research assistants from standardized components go.nature.com/3JmqKux
rdcu.be/ePz3v
BioContextAI is a community hub for agentic biomedical systems - Nature Biotechnology
Nature Biotechnology - BioContextAI is a community hub for agentic biomedical systems
go.nature.com
November 12, 2025 at 3:04 PM
Reposted by Victor Puelles
The Eknoyan Lectureship at #KidneyWk will cover KDIGO Guidelines for CKD on Saturday. Read about the speaker in #ASNKidneyNews kidney.pub/KN1710-55
November 6, 2025 at 9:00 PM
Reposted by Victor Puelles
At #KidneyWk? Celebrate and listen to the ASN-American Heart Association Donald W. Seldin Young Investigator Award winner, Rafael Kramann, who will speak on “Cell by Cell, Space by Space: Unraveling Fibrosis in the Kidney and Heart” on Friday, November 7. kidney.pub/KN1710-35 #ASNKidneyNews
November 6, 2025 at 10:00 PM
Reposted by Victor Puelles
BioContextAI is a community hub for agentic biomedical systems - @puellesv.bsky.social @biocontext.ai go.nature.com/3JmqKux
BioContextAI is a community hub for agentic biomedical systems - Nature Biotechnology
Nature Biotechnology - BioContextAI is a community hub for agentic biomedical systems
go.nature.com
November 6, 2025 at 6:28 PM
Reposted by Victor Puelles
🤖🧬 New biomedical MCP server added to the registry:
Skill-To-MCP Server
Check it out at https://biocontext.ai/registry/biocontext-ai/skill-to-mcp
October 26, 2025 at 7:55 PM
Reposted by Victor Puelles
Our new review in @natbiomedeng.nature.com is out!
RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits.
free to read 🔗 rdcu.be/eLxGs
Targeting and tracking mRNA lipid nanoparticles at the particle, transcript and protein level
Nature Biomedical Engineering - This Review explores strategies for targeting and tracking RNA-LNP drugs, monitoring their in vivo behaviour, enhancing tissue-specific delivery, and using synthetic...
rdcu.be
October 17, 2025 at 5:16 PM
Reposted by Victor Puelles
The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery.
#Microscopy #Lightsheet #syGlass
October 23, 2025 at 3:33 PM
Reposted by Victor Puelles
🦠🔬🤖🧑‍💻 #mAIcrobe is out! With @pinholab.bsky.social's lab, we launched an open-source framework for high-throughput bacterial image analysis. By rockstars A. Brito & B. Saraiva et al, making #DeepLearning for phenotyping accessible! Easy to use, plus model training

📜 www.biorxiv.org/content/10.1...
October 22, 2025 at 11:10 AM
Reposted by Victor Puelles
Job opportunity at the University of Zurich! 📢

We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.

1/3
October 10, 2025 at 8:58 AM
Reposted by Victor Puelles
✨🥳🎉 Heartfelt congratulations to Humboldtians Susumu Kitagawa and Omar M. Yaghi on winning the #NobelPrize in Chemistry 2025 which they share with Richard Robson for the development of "metal-organic frameworks"!

We are truly honoured to have supported a step in their exceptional journey! 💚
October 8, 2025 at 10:50 AM