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Eduardo Villablanca

@ejvillablanca.bsky.social

3.5K followers 210 following 150 posts

Mucosal Immunologist interested in the complexity of IBD. Professor @Karolinskainst, Wallenberg Fellow & editor @MucosalImmunol. Opinions are my own

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Eduardo Villablanca @ejvillablanca.bsky.social · Nov 16

Welcome to our new KI lab webpage!

Inflammatory bowel disease (IBD) – Research group Eduardo Villablanca

ki.se/en/research/...

Inflammatory bowel disease (IBD) – Research group Eduardo Villablanca

Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is a manifestation of an inappropriate inflammatory response to intestinal microorganisms in genetically s...

ki.se

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Reposted by Eduardo Villablanca

Lorenz Adlung Lab @adlunglab.com · 5d

Great reference to get up to speed on B cells in IBD from our good friend @ejvillablanca.bsky.social
TL;DR B cells aren’t just bystanders in IBD, they’re active players in both gut protection, pathology and mucosal healing.
doi.org/10.1016/j.im... 🧪

B cells in inflammatory bowel disease

Inflammatory bowel diseases (IBD) have traditionally been considered T cell-driven disorders; however, accumulating evidence challenges this view and …

doi.org

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Eduardo Villablanca @ejvillablanca.bsky.social · 5d

Yesterday marked my installation as Professor at Karolinska Institutet

I’m extremely grateful to my family, friends, and lab members who joined to celebrate this milestone.

Excited for the journey ahead!

@ki.se

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Eduardo Villablanca @ejvillablanca.bsky.social · 6d

Saddened to hear of Sir John Gurdon’s passing at 92. His pioneering work in nuclear reprogramming laid the foundation for modern stem cell biology. A true giant of developmental biology and an inspiration to generations.

Nobel Laureate (2012, with Shinya Yamanaka).

👇🏼being grilled by him :)

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Eduardo Villablanca @ejvillablanca.bsky.social · 7d

Thanks @societymucosalimm.bsky.social for highlighting our work!

Kudos to Francisca and Bianca for an amazing job!

Society for Mucosal Immunology @societymucosalimm.bsky.social · 7d

SMI Member Eduardo Villablanca and colleagues review B cells in inflammatory bowel disease at Immunology Letters:
www.sciencedirect.com/science/arti...

#SMIMemberPaper #MucosalImmunology #Immunology

Eduardo Villablanca @ejvillablanca.bsky.social · 8d

This is how we experience the Nobel Prize announcement every year, with excitement!

This year was extra special, as we celebrated the immunology and Treg!

👇🏼 Listening to our department prefect and lab neighbor, Marie Wahren, beautifully explaining the motivation behind this year’s #nobelprize

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Eduardo Villablanca @ejvillablanca.bsky.social · 19d

CD19 CAR T-Cell Therapy in Multidrug-Resistant Ulcerative Colitis | New England Journal of Medicine www.nejm.org/doi/full/10....

CD19 CAR T-Cell Therapy in Multidrug-Resistant Ulcerative Colitis | NEJM

In a patient with treatment-resistant ulcerative colitis, CD19 CAR T-cell therapy led to drug-free remission and mucosal healing, suggesting that B-cell targeting may offer a novel therapeutic ...

www.nejm.org

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Eduardo Villablanca @ejvillablanca.bsky.social · 20d

Karolinska Institutet organizes an Installation Ceremony every fall, where new professors at KI are inaugurated and presented.

This year, it is my turn to be installed :) 😍

"Studying how inflammation starts and heals in the gut"

news.ki.se/studying-how...

Studying how inflammation starts and heals in the gut

Inflammatory bowel disease affects millions of people worldwide and currently lacks a cure. Eduardo Villablanca studies how inflammation starts and heals in the intestines, with the aim to find new tr...

news.ki.se

Eduardo Villablanca @ejvillablanca.bsky.social · 27d

Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures

#IBD

www.sciencedirect.com/science/arti...

Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures

A significant complication of Crohn’s disease (CD) is intestinal fibrosis, which narrows the bowel lumen to form a stricture. Creeping fat (CF) is the…

www.sciencedirect.com

Eduardo Villablanca @ejvillablanca.bsky.social · 28d

We miss you too!!!

Reposted by Eduardo Villablanca

Waggoner Lab @labwaggoner.bsky.social · Sep 11

The gut microbiota directs vitamin A flux to regulate intestinal T cell development @biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...

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Eduardo Villablanca @ejvillablanca.bsky.social · Sep 9

Extremely proud of @xinxinluo.bsky.social for winning the Dimitris N. Chorafas Prize 2025!

Awarded “for her groundbreaking work on inflammation, tissue damage & repair in the intestine, with innovative methods & impactful collaborations.”

So proud! 👏

news.ki.se/xinxin-luo-r...

@ki.se
#IBD

news.ki.se

Eduardo Villablanca @ejvillablanca.bsky.social · Sep 9

If you want to contribute to strategic areas of data-driven research within the Data-Driven Life Science (DDLS) program in Sweden, three of the DDLS research area expert groups are now seeking additional members!

Join us in helping shape data-driven research.

www.scilifelab.se/news/express...

Expression of interest call: Three of the DDLS research area expert groups now seek additional members

Are you an established expert within Data Driven Cell and Molecular biology, Epidemiology and biology of infection or Evolution and Biodiversity research, three of the four strategic areas for data-dr...

www.scilifelab.se

Eduardo Villablanca @ejvillablanca.bsky.social · Sep 5

IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

Cell www.cell.com/cell/fulltex...

IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

IL-25 treatment induces persistent adaptation of the small intestine, which is maintained by ILC2s with functional and epigenetic qualities of immune memory. Effector-memory ILC2s arise in multiple ti...

www.cell.com

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Eduardo Villablanca @ejvillablanca.bsky.social · Aug 30

🎉 Huge congratulations to @immunologyking.bsky.social & @maurogaya.bsky.social for an outstanding @embo.org workshop:

adaptive immunity in barrier tissues

Brilliant science, inspiring discussions, and friendships that make it one of the best!

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Eduardo Villablanca @ejvillablanca.bsky.social · Aug 27

Great analogy to illustrate the question @carlanowosad.bsky.social is pursuing on her lab: how GC are form and how GC cells find their way to their specific locations

#embo workshop Basel

#immunalogy

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Eduardo Villablanca @ejvillablanca.bsky.social · Aug 21

Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy: Cell www.cell.com/cell/fulltex...

Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy

SPPL3 deletion modifies glycosylation on primary T cells, reducing allogeneic immune responses without impairing tumor control by anti-CD19 allogeneic CAR-T cells. SPPL3-null, TCR-sufficient anti-CD19...

www.cell.com

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Eduardo Villablanca @ejvillablanca.bsky.social · Aug 20

#Bcells are emerging as key players in #IBD, far beyond a T-cell story.

From IgA protection to pro-inflammatory subsets, we highlight how understanding B cell diversity can unlock precise #Immunotherapy in #IBD.

Check Fran and Bianca's review 👇

doi.org/10.1016/j.im...

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Eduardo Villablanca @ejvillablanca.bsky.social · Aug 20

what about this: doi.org/10.1016/j.im...

Redirecting

doi.org

Eduardo Villablanca @ejvillablanca.bsky.social · Aug 17

@drsalinaslab.bsky.social

Eduardo Villablanca @ejvillablanca.bsky.social · Aug 16

Thrilled to welcome Irene Salinas to our lab for her sabbatical! A true role model scientist who has already energized us with inspiring discussions in evolutionary immunology.

Looking forward more exciting scientific explorations and great conversations together
#ScienceCommunity #Collaboration

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Reposted by Eduardo Villablanca

Sten Linnarsson @sten.linnarsson.org · Jun 25

A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)

Karolinska Institutet @ki.se · Jun 25

Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential.
🔗 All positions: ki.se/en/about-ki/...

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Eduardo Villablanca @ejvillablanca.bsky.social · Aug 16

Breast milk IgG engages the mouse neonatal immune system to instruct responses to gut antigens | Science www.science.org/doi/10.1126/...

Breast milk IgG engages the mouse neonatal immune system to instruct responses to gut antigens

Maternal antibodies fundamentally regulate gut immunity in the developing infant, yet the mechanisms underlying this process remain elusive. We found that maternal immunoglobulin G (IgG), ingested in ...

www.science.org

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Eduardo Villablanca @ejvillablanca.bsky.social · Aug 6

New lab uniform

Reposted by Eduardo Villablanca

Achille Broggi🧪👨🏼‍🔬🔬 @achillebro.bsky.social · Jul 31

Thanks so much to Mathias Hornef, Oliver Pabst and Heike for organizing the beautiful #EMIG2025 in @rwth.bsky.social . This nice picture really captures the mood of this amazing conference. @ejvillablanca.bsky.social @gmagrilab.bsky.social

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Eduardo Villablanca @ejvillablanca.bsky.social · Jul 27

No se lo pierda!

Pasaporte Ciencia | Capítulo 5 | Suecia www.13.cl/programas/pa...

Pasaporte Ciencia | Capítulo 5 | Suecia

Sitio web oficial de Canal 13, primer canal de transmisión chileno en transformarse en una casa editorial que traspasa sus contenidos a todas sus plataformas como Internet, radio, cable y eventos mult...