Thomas Pradeu
@pradeu.bsky.social
CNRS Research Director, Philosophy of Science and Theoretical Biology. Works on Immunology, cancer, and microbiome. CNRS & University of Bordeaux, France.
Reposted by Thomas Pradeu
PPP2R1A mutations are linked to improved response to immunotherapy in ovarian clear cell carcinoma @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 2, 2025 at 8:21 PM
PPP2R1A mutations are linked to improved response to immunotherapy in ovarian clear cell carcinoma @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Thomas Pradeu
International students enrich university communities and strengthen civic life. We must defend their place in global education. @nature.com @mchankseliani.bsky.social
www.nature.com/articles/d41...
www.nature.com/articles/d41...
What we stand to lose when foreign students are seen as a threat
International students enrich university communities and strengthen civic life. We must defend their place in global education.
www.nature.com
July 2, 2025 at 8:22 PM
International students enrich university communities and strengthen civic life. We must defend their place in global education. @nature.com @mchankseliani.bsky.social
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Thomas Pradeu
The Somatic Mosaicism across Human Tissues Network @nature.com @timcoorens.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 2, 2025 at 8:27 PM
The Somatic Mosaicism across Human Tissues Network @nature.com @timcoorens.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Thomas Pradeu
Functional amyloid proteins confer defense against predatory bacteria @nature.com @hannahledvina.bsky.social @aaronwhiteley.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Functional amyloid proteins confer defence against predatory bacteria - Nature
Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a mechanism th...
www.nature.com
July 2, 2025 at 8:29 PM
Functional amyloid proteins confer defense against predatory bacteria @nature.com @hannahledvina.bsky.social @aaronwhiteley.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Thomas Pradeu
The mutagenic forces shaping the genomes of lung cancer in never smokers @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 2, 2025 at 8:31 PM
The mutagenic forces shaping the genomes of lung cancer in never smokers @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Thomas Pradeu
Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T cell therapy for leukemia @sabaghassemi.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 2, 2025 at 8:35 PM
Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T cell therapy for leukemia @sabaghassemi.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Thomas Pradeu
Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
June 30, 2025 at 4:00 PM
Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
New paper out! rdcu.be/etKdN Experts in #cancer across the tree of life and philosophers of science teamed up to explore how comparative thinking can improve current approaches to cancer, including conceptually and therapeutically. #evolution #ecology #oncology #philosophy
Advancing cancer research via comparative oncology
Nature Reviews Cancer - Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular...
rdcu.be
June 30, 2025 at 7:48 AM
New paper out! rdcu.be/etKdN Experts in #cancer across the tree of life and philosophers of science teamed up to explore how comparative thinking can improve current approaches to cancer, including conceptually and therapeutically. #evolution #ecology #oncology #philosophy
Reposted by Thomas Pradeu
We are looking forward to an exciting week with great speakers, interesting discussions on Philosophy in Science and intriguing project work! (4/4)
June 3, 2025 at 5:09 PM
We are looking forward to an exciting week with great speakers, interesting discussions on Philosophy in Science and intriguing project work! (4/4)
Reposted by Thomas Pradeu
James DiFrisco (Crick Institute, UK) on "Moving beyond conceptual analysis: conceptual methodology for philosophy 'in' science"
June 3, 2025 at 5:05 PM
James DiFrisco (Crick Institute, UK) on "Moving beyond conceptual analysis: conceptual methodology for philosophy 'in' science"
Reposted by Thomas Pradeu
Some impressions of the first day of the #PhilInBioMed at University of Bordeaux! (1/?)
Full program here: www.philinbiomed.org/event/bordea...
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
Full program here: www.philinbiomed.org/event/bordea...
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
June 3, 2025 at 4:59 PM
Some impressions of the first day of the #PhilInBioMed at University of Bordeaux! (1/?)
Full program here: www.philinbiomed.org/event/bordea...
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
Full program here: www.philinbiomed.org/event/bordea...
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
Reposted by Thomas Pradeu
And obviously, conversations continue during the coffee breaks.
June 3, 2025 at 5:14 PM
And obviously, conversations continue during the coffee breaks.
Reposted by Thomas Pradeu
Bertrand Daignan-Fornier on "Biomass experience"
June 3, 2025 at 5:12 PM
Bertrand Daignan-Fornier on "Biomass experience"
Reposted by Thomas Pradeu
Impressions of Day 2 of the #PhilInBioMed at University of Bordeaux! (1/?)
Full program here: www.philinbiomed.org/event/bordea...
Marie Vasse on "Predictions and Unexpectedness"
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
Full program here: www.philinbiomed.org/event/bordea...
Marie Vasse on "Predictions and Unexpectedness"
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
June 3, 2025 at 5:11 PM
Impressions of Day 2 of the #PhilInBioMed at University of Bordeaux! (1/?)
Full program here: www.philinbiomed.org/event/bordea...
Marie Vasse on "Predictions and Unexpectedness"
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
Full program here: www.philinbiomed.org/event/bordea...
Marie Vasse on "Predictions and Unexpectedness"
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
Reposted by Thomas Pradeu
My colleague and friend @scripps.edu, @ardemp.bskyverified.social, on the NYT front page today
June 4, 2025 at 2:47 PM
My colleague and friend @scripps.edu, @ardemp.bskyverified.social, on the NYT front page today
Reposted by Thomas Pradeu
#Science #Environnement
🐜 "Les invasions biologiques, la menace oubliée"
👨🏫 Franck Courchamp, professeur invité sur la chaire annuelle Biodiversité et écosystèmes, introduit son cours de l'année 2024-2025
⏰ Jusqu'au lundi 30 juin 2025
Voir la suite 👉 www.college-de-france.fr/fr/agenda/co...
🐜 "Les invasions biologiques, la menace oubliée"
👨🏫 Franck Courchamp, professeur invité sur la chaire annuelle Biodiversité et écosystèmes, introduit son cours de l'année 2024-2025
⏰ Jusqu'au lundi 30 juin 2025
Voir la suite 👉 www.college-de-france.fr/fr/agenda/co...
June 5, 2025 at 5:09 AM
#Science #Environnement
🐜 "Les invasions biologiques, la menace oubliée"
👨🏫 Franck Courchamp, professeur invité sur la chaire annuelle Biodiversité et écosystèmes, introduit son cours de l'année 2024-2025
⏰ Jusqu'au lundi 30 juin 2025
Voir la suite 👉 www.college-de-france.fr/fr/agenda/co...
🐜 "Les invasions biologiques, la menace oubliée"
👨🏫 Franck Courchamp, professeur invité sur la chaire annuelle Biodiversité et écosystèmes, introduit son cours de l'année 2024-2025
⏰ Jusqu'au lundi 30 juin 2025
Voir la suite 👉 www.college-de-france.fr/fr/agenda/co...
Reposted by Thomas Pradeu
The first generative AI drug to get to a Phase 2 randomized clinical trial. The small molecule in pill form, rentosertib, showed signs of efficacy for idiopathic pulmonary fibrosis @naturemedicine.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
June 3, 2025 at 1:03 PM
The first generative AI drug to get to a Phase 2 randomized clinical trial. The small molecule in pill form, rentosertib, showed signs of efficacy for idiopathic pulmonary fibrosis @naturemedicine.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Thomas Pradeu
Thanks to @asm.org for joining this letter and calling for Congressional oversight so that NSF can fulfill its Congressionally-mandated mission and support US science
June 3, 2025 at 1:15 PM
Thanks to @asm.org for joining this letter and calling for Congressional oversight so that NSF can fulfill its Congressionally-mandated mission and support US science
Reposted by Thomas Pradeu
Great to see @ascbiology.bsky.social join 52 other science societies in a letter to Congress expressing concern over recent organizational and financial developments at NSF, and urging Congress to exercise its oversight authority to preserve American STEM leadership 1/n
aas.org/sites/defaul...
aas.org/sites/defaul...
aas.org
June 2, 2025 at 8:33 PM
Great to see @ascbiology.bsky.social join 52 other science societies in a letter to Congress expressing concern over recent organizational and financial developments at NSF, and urging Congress to exercise its oversight authority to preserve American STEM leadership 1/n
aas.org/sites/defaul...
aas.org/sites/defaul...
Reposted by Thomas Pradeu
Register for our next ECLC webinar by Marco Montagner, PhD on Understanding the determinants of the invisible phase of metastasis - June 26th, 2025 - USA: 11:00 AM EDT | Europe: 17:00 PM CEST | Australia: 01:00 AM AEST - tinyurl.com/ujer8yw8
June 3, 2025 at 1:17 PM
Register for our next ECLC webinar by Marco Montagner, PhD on Understanding the determinants of the invisible phase of metastasis - June 26th, 2025 - USA: 11:00 AM EDT | Europe: 17:00 PM CEST | Australia: 01:00 AM AEST - tinyurl.com/ujer8yw8
Reposted by Thomas Pradeu
🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues.
📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025
Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social
#EMBOBarrierTissues
📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025
Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social
#EMBOBarrierTissues
Adaptive immunity in barrier tissues
Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…
meetings.embo.org
April 30, 2025 at 3:04 PM
🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues.
📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025
Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social
#EMBOBarrierTissues
📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025
Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social
#EMBOBarrierTissues
Reposted by Thomas Pradeu
🥁NEW publication from our lab:
the largest meta-analysis of gut microbiome associations with CRC!
www.nature.com/articles/s41...
🧵⬇️
1/6
the largest meta-analysis of gut microbiome associations with CRC!
www.nature.com/articles/s41...
🧵⬇️
1/6
Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer - Nature Medicine
An analysis of 18 metagenomic datasets of individuals with colorectal cancer, adenomas and healthy controls yields improved cancer prediction accuracy based solely on gut metagenomics, as well as the ...
www.nature.com
June 3, 2025 at 10:43 AM
🥁NEW publication from our lab:
the largest meta-analysis of gut microbiome associations with CRC!
www.nature.com/articles/s41...
🧵⬇️
1/6
the largest meta-analysis of gut microbiome associations with CRC!
www.nature.com/articles/s41...
🧵⬇️
1/6
Reposted by Thomas Pradeu
TSSpredator-Web: A web-application for transcription start site prediction and exploration https://www.biorxiv.org/content/10.1101/2025.05.29.656934v1
June 2, 2025 at 1:48 AM
TSSpredator-Web: A web-application for transcription start site prediction and exploration https://www.biorxiv.org/content/10.1101/2025.05.29.656934v1
Reposted by Thomas Pradeu
What theoretical & methodological challenges emerge when investigating #behavior across the tree of life? We are organizing an interdisciplinary workshop on 'comparative behavioral biology' (Sept. 26-27). Please help us share the open CfA! 📢👇 hiw.kuleuven.be/clps/events/... #philsci #HPbio #evobio
June 3, 2025 at 1:26 PM
What theoretical & methodological challenges emerge when investigating #behavior across the tree of life? We are organizing an interdisciplinary workshop on 'comparative behavioral biology' (Sept. 26-27). Please help us share the open CfA! 📢👇 hiw.kuleuven.be/clps/events/... #philsci #HPbio #evobio
Reposted by Thomas Pradeu
The #PhilInBioMed Summer School has started!
Five days of exciting talks, big ideas, and fun crossovers between philosophy, biology, and medicine.
@philinbiomed.bsky.social
👉 www.philinbiomed.org/event/bordea...
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
Five days of exciting talks, big ideas, and fun crossovers between philosophy, biology, and medicine.
@philinbiomed.bsky.social
👉 www.philinbiomed.org/event/bordea...
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
June 2, 2025 at 9:50 AM
The #PhilInBioMed Summer School has started!
Five days of exciting talks, big ideas, and fun crossovers between philosophy, biology, and medicine.
@philinbiomed.bsky.social
👉 www.philinbiomed.org/event/bordea...
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool
Five days of exciting talks, big ideas, and fun crossovers between philosophy, biology, and medicine.
@philinbiomed.bsky.social
👉 www.philinbiomed.org/event/bordea...
#BSS2025 #Philosophy #Biology #Medicine #SummerSchool