Poepsel Lab
poepsel-lab.bsky.social
Poepsel Lab
@poepsel-lab.bsky.social
Chromatin Biochemistry and Structural Biology @Center for Molecular Medicine Cologne (CMMC), University Clinic Cologne, Germany
Reposted by Poepsel Lab
New work in a great team effort with the @poepsel-lab.bsky.social. We identified novel interactors of AIFM1 and found that this protein once only associated with cell death is a master organizer of the mito-IMS: By interaction with AK2 and SLC25 family members ensuring metabolic adaptation.
June 26, 2025 at 7:32 PM
Reposted by Poepsel Lab
I have had the privilege to train many chinese students over many years. They enriched our lives and did great science. Many are still here and contribute to the US scientific enterprise. The push to revoke student visas is cruel and unnecessary. We must push back.
www.npr.org/2025/05/28/g...
Rubio says U.S. will 'aggressively' revoke visas for many Chinese students
The announcement to revoke visas is the most drastic move yet to curtail the numbers of international students studying in the U.S.
www.npr.org
May 29, 2025 at 12:49 PM
Reposted by Poepsel Lab
Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism"
—the 1st human to undergo custom genome editing
—from decades of NIH funded research
www.nejm.org/doi/full/10....
@nejm.org
www.nejm.org/doi/full/10....
www.nytimes.com/2025/05/15/h...
May 15, 2025 at 6:05 PM
Reposted by Poepsel Lab
Excited to share our latest work, led by the incredible @automnenine.bsky.social (now an Ass. Prof. at Princeton)! We uncover key insights into the retrotransposition mechanisms of LINE-1 ORF2p, the enzyme responsible for writing a significant portion of our genome.
www.science.org/doi/10.1126/...
Structural mechanism of LINE-1 target-primed reverse transcription
Long interspersed element-1 (LINE-1) retrotransposons are the only active autonomous transposable elements in humans. They propagate by reverse transcribing their mRNA into new genomic locations by a ...
www.science.org
March 6, 2025 at 9:33 PM