Mokranjac Lab
mokranjaclab.bsky.social
Mokranjac Lab
@mokranjaclab.bsky.social
Working on biogenesis and quality control of mitochondria.
Pinned
New publication alert!!!🥳 We identified Pth2 as a peptidyl tRNA hydrolase in the mitoRQC pathway! Thank you to all the co-authors!! @cp-molcell.bsky.social @dfg.de @osman-lab.bsky.social @lmumuenchen.bsky.social
doi.org/10.1016/j.mo...
#Pth2 #mitochondria #mitoRQC #qualitycontrol
Reposted by Mokranjac Lab
Join us today (Wednesday, Nov 26) for a talk by Dejana Mokranjac from the Ludwig-Maximilians-Universität in Munich -she is going to present the latest results from her mitochondrial research.
We are very much looking forward to her presentation!

@mokranjaclab.bsky.social
November 26, 2025 at 8:32 AM
Reposted by Mokranjac Lab
Schreiner, Mikeladze-Dvali et al. @lifescimunich.bsky.social show that CDK-1 primes PCMD-1 for PLK-1 phosphorylation. Mutations in PLK-1 docking sites impair SPD-5 binding, destabilize the PCM, and delay #centriole separation. rupress.org/jcb/article/...

#Centrosome #PCMstability #Celegans
October 31, 2025 at 4:45 PM
New publication alert!!!🥳 We identified Pth2 as a peptidyl tRNA hydrolase in the mitoRQC pathway! Thank you to all the co-authors!! @cp-molcell.bsky.social @dfg.de @osman-lab.bsky.social @lmumuenchen.bsky.social
doi.org/10.1016/j.mo...
#Pth2 #mitochondria #mitoRQC #qualitycontrol
October 21, 2025 at 3:42 PM
Reposted by Mokranjac Lab
🏅We congratulate 🌟Nils Bertram🌟 @lmumuenchen.bsky.social, on winning a FEBS Letters #PosterPrize at the #EMBOFEBSproteostasis meeting, held in Espoo, Finland! 🎉👏👏👏

📸 Photo: Nils with our Managing Editor, Dr. Duncan Wright
October 9, 2025 at 1:01 PM
Thank you for publishing our hardwork!!✨️ @emboreports.org
Dejana Mokranjac @mokranjaclab.bsky.social identifies a pathway for #oxidation and assembly of mitochondrial inner #membrane proteins involving Dbi1 as oxidoreductase and assembly #chaperone for #mitochondria inner membrane proteins.

-> www.embopress.org/doi/full/10....
June 1, 2025 at 2:53 PM
Congratulations to the team on this cool story!✨️
How does an unusual heptameric AAA-ATPase translocate fully-folded Rieske protein across the inner mitochondrial membrane?
Cryo-EM & functional data by Roland Beckmann and coworkers show how Bcs1 alternates between different states during its translocation activity.
www.embopress.org/doi/full/10....
June 1, 2025 at 2:49 PM