Dr. Amy Lee
@minisciencegirl.bsky.social
Assistant Professor @ SFU MBB | Systems Biology of Host-Pathogen | Vaccinology | Neonatal Sepsis | Pathogen Genomics | Loves data, food & art.
Pinned
Dr. Amy Lee
@minisciencegirl.bsky.social
· Nov 21
Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation
Despite appearing healthy at birth, neonates who later developed EOS already had distinct
whole blood gene expression changes at birth, which enabled the development of a 4-gene
predictive signature f...
www.thelancet.com
Every year, >200K newborns die from sepsis.
Our team used machine learning to develop a set of genes that can predict neonatal sepsis risk using at birth blood samples.
www.thelancet.com/journals/ebi...
Reposted by Dr. Amy Lee
November 24, 2025 at 11:46 PM
Reposted by Dr. Amy Lee
3 infant #pertussis deaths this year in Kentucky. "Of the three infant deaths reported over the past 12 months, all three were not vaccinated, nor were their mothers."
We first tested maternal vaccination for whooping cough over 80 years ago. It's safe & effective & might have saved these babies.
We first tested maternal vaccination for whooping cough over 80 years ago. It's safe & effective & might have saved these babies.
www.wowktv.com
November 25, 2025 at 1:27 AM
3 infant #pertussis deaths this year in Kentucky. "Of the three infant deaths reported over the past 12 months, all three were not vaccinated, nor were their mothers."
We first tested maternal vaccination for whooping cough over 80 years ago. It's safe & effective & might have saved these babies.
We first tested maternal vaccination for whooping cough over 80 years ago. It's safe & effective & might have saved these babies.
Reposted by Dr. Amy Lee
Reposted by Dr. Amy Lee
Setting aside the question of whether or not we are ready to phase out the use of animals in research (spoiler: we are not), there is an ethical way to do this. Abruptly shutting down research programs means that many animals are going to be euthanized! www.science.org/content/arti...
Exclusive: CDC to end all monkey research
Studies related to HIV and other infectious diseases will be phased out, sources say; fate of the agency's animals remains unclear
www.science.org
November 24, 2025 at 1:01 AM
Setting aside the question of whether or not we are ready to phase out the use of animals in research (spoiler: we are not), there is an ethical way to do this. Abruptly shutting down research programs means that many animals are going to be euthanized! www.science.org/content/arti...
Brilliant, heartbreaking story.
Oh this broke my heart today —
“I feel so cheated and so sad that I don’t get to keep living the wonderful life I had with this kind, funny, handsome genius I managed to find.”
“A Battle with My Blood” by Tatiana Schlossberg
“I feel so cheated and so sad that I don’t get to keep living the wonderful life I had with this kind, funny, handsome genius I managed to find.”
“A Battle with My Blood” by Tatiana Schlossberg
A Battle with My Blood
When I was diagnosed with leukemia, my first thought was that this couldn’t be happening to me, to my family.
www.newyorker.com
November 23, 2025 at 3:30 PM
Brilliant, heartbreaking story.
Reposted by Dr. Amy Lee
After years of research, we now have innovations that are more affordable, context-specific, and able to be decentralized.
High TB burden countries must adopt this newfound capacity to address the diagnostic gap that is preventing them from ending the TB epidemic
www.devex.com/news/global-...
High TB burden countries must adopt this newfound capacity to address the diagnostic gap that is preventing them from ending the TB epidemic
www.devex.com/news/global-...
November 21, 2025 at 8:15 PM
After years of research, we now have innovations that are more affordable, context-specific, and able to be decentralized.
High TB burden countries must adopt this newfound capacity to address the diagnostic gap that is preventing them from ending the TB epidemic
www.devex.com/news/global-...
High TB burden countries must adopt this newfound capacity to address the diagnostic gap that is preventing them from ending the TB epidemic
www.devex.com/news/global-...
Check out a cool new collaboration we have with @fraserhealth.ca @fraserhealthbc.bsky.social to track C difficile transmission and infection. www.fraserhealth.ca/news/2025/No...
Fraser Health and Simon Fraser University launch pilot project to decode superbug’s genetic secrets
Fraser Health and Simon Fraser University (SFU) have launched a pilot project to sequence the genome of Clostridioides difficile, a superbug responsible for severe infections.
www.fraserhealth.ca
November 21, 2025 at 8:38 PM
Check out a cool new collaboration we have with @fraserhealth.ca @fraserhealthbc.bsky.social to track C difficile transmission and infection. www.fraserhealth.ca/news/2025/No...
Reposted by Dr. Amy Lee
Solve a real global health challenge, pitch solutions, and learn with peers across disciplines.
And yes, there are cash prizes & food.
If of interest @nedasoc.bsky.social, @alanrichardson.bsky.social, @profkharrison.bsky.social, @bmatb.expmicromech.com, @sethabrutyn.bsky.social
And yes, there are cash prizes & food.
If of interest @nedasoc.bsky.social, @alanrichardson.bsky.social, @profkharrison.bsky.social, @bmatb.expmicromech.com, @sethabrutyn.bsky.social
November 20, 2025 at 9:19 PM
Solve a real global health challenge, pitch solutions, and learn with peers across disciplines.
And yes, there are cash prizes & food.
If of interest @nedasoc.bsky.social, @alanrichardson.bsky.social, @profkharrison.bsky.social, @bmatb.expmicromech.com, @sethabrutyn.bsky.social
And yes, there are cash prizes & food.
If of interest @nedasoc.bsky.social, @alanrichardson.bsky.social, @profkharrison.bsky.social, @bmatb.expmicromech.com, @sethabrutyn.bsky.social
Reposted by Dr. Amy Lee
UBC and SFU PIH chapters are partnering with us to host a Global Health Case Competition — built by students, for students. Happening next Sat, Nov 29th.
If of interest @ubcpress.bsky.social @ccj-ubc.bsky.social @ires.ubc.ca @jwmartens.bsky.social @profterrig.bsky.social @lauraknelson.bsky.social
If of interest @ubcpress.bsky.social @ccj-ubc.bsky.social @ires.ubc.ca @jwmartens.bsky.social @profterrig.bsky.social @lauraknelson.bsky.social
November 20, 2025 at 9:19 PM
UBC and SFU PIH chapters are partnering with us to host a Global Health Case Competition — built by students, for students. Happening next Sat, Nov 29th.
If of interest @ubcpress.bsky.social @ccj-ubc.bsky.social @ires.ubc.ca @jwmartens.bsky.social @profterrig.bsky.social @lauraknelson.bsky.social
If of interest @ubcpress.bsky.social @ccj-ubc.bsky.social @ires.ubc.ca @jwmartens.bsky.social @profterrig.bsky.social @lauraknelson.bsky.social
Reposted by Dr. Amy Lee
With a new flu virus variant circulating, scientists fear more sickness this winter. The vaccine may be slightly less effective but doctors still urge getting one ASAP. n.pr/3X18OZx
Flu season could be nasty this winter
With a new flu virus variant circulating, scientists fear more sickness this winter. The vaccine may be slightly less effective but doctors still urge getting one ASAP.
n.pr
November 19, 2025 at 11:20 AM
With a new flu virus variant circulating, scientists fear more sickness this winter. The vaccine may be slightly less effective but doctors still urge getting one ASAP. n.pr/3X18OZx
Reposted by Dr. Amy Lee
Major new direction in the lab: hacking human cell biology with pathogen effectors (eORFs) - amazing collaboration with @miketilapia.bsky.social lab. Huge congrats to first authors Tomas & He & all co-authors! Check out the pre-print on @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
www.biorxiv.org
November 18, 2025 at 2:51 PM
Major new direction in the lab: hacking human cell biology with pathogen effectors (eORFs) - amazing collaboration with @miketilapia.bsky.social lab. Huge congrats to first authors Tomas & He & all co-authors! Check out the pre-print on @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
Reposted by Dr. Amy Lee
Excited to share this work where we found how fish swim differently to keep balance in the dark / explore more in the light.
Spoiler: ever wonder what they do during “little pauses” between swims? They are counting!
Spoiler: ever wonder what they do during “little pauses” between swims? They are counting!
Like most animals, fish move less at night. Underwater, stable posture requires movement. Find out how fish don't fall down at night in: Lighting and circadian cues shape locomotor strategies for balance and navigation in larval zebrafish from @yunluzhu.bsky.social
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Lighting and circadian cues shape locomotor strategies for balance and navigation in larval zebrafish
Most fish are inherently unstable and must swim to stabilize posture. How diurnal fish reduce activity at night while maintaining postural control remains unclear. We defined distinct locomotor strate...
doi.org
November 19, 2025 at 4:11 AM
Excited to share this work where we found how fish swim differently to keep balance in the dark / explore more in the light.
Spoiler: ever wonder what they do during “little pauses” between swims? They are counting!
Spoiler: ever wonder what they do during “little pauses” between swims? They are counting!
Reposted by Dr. Amy Lee
“More than a decade after the first HPV vaccination programmes rolled out, data from multiple countries reveals a dramatic fall in cervical cancers and precancers, confirming that HPV vaccines are highly effective and extremely safe”
www.gavi.org/vaccineswork...
www.gavi.org/vaccineswork...
The HPV vaccine is erasing cancer – here's the proof
More than a decade after the first HPV vaccination programmes rolled out, data from multiple countries reveals a dramatic fall in cervical cancers and precancers, confirming that HPV vaccines are high...
www.gavi.org
November 19, 2025 at 1:38 AM
“More than a decade after the first HPV vaccination programmes rolled out, data from multiple countries reveals a dramatic fall in cervical cancers and precancers, confirming that HPV vaccines are highly effective and extremely safe”
www.gavi.org/vaccineswork...
www.gavi.org/vaccineswork...
Reposted by Dr. Amy Lee
Introducing Foli-seq in @natbiotech.nature.com today. Foli-seq can be used to measure gut-derived RNA from fecal matter (signals of immune, secretory & epithelial cells). We used this to map gut inflammation, drug response, and host-microbe interactions. 💩🧬💊🦠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Fecal exfoliome sequencing captures immune dynamics of the healthy and inflamed gut - Nature Biotechnology
Profiling host RNA shed in feces reveals disease states in the gut.
www.nature.com
November 17, 2025 at 8:55 PM
Introducing Foli-seq in @natbiotech.nature.com today. Foli-seq can be used to measure gut-derived RNA from fecal matter (signals of immune, secretory & epithelial cells). We used this to map gut inflammation, drug response, and host-microbe interactions. 💩🧬💊🦠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Dr. Amy Lee
They. Are. Kidnapping. People. Including. Children. And. Putting. Them. In. Grotesque. Detention. Centers. Under. Inhumane. Conditions. And. Hundreds. Have. Disappeared. And. They. Are. Terrorizing. Children. And. Zip-Tying. Children. And. Tear. Gassing. Children. For. Fuck's. Sake.
possible future class action lawsuits on the inhumane and illegal actions of ICE and those in charge condoning their behavior are going to be historic.
November 17, 2025 at 9:43 PM
They. Are. Kidnapping. People. Including. Children. And. Putting. Them. In. Grotesque. Detention. Centers. Under. Inhumane. Conditions. And. Hundreds. Have. Disappeared. And. They. Are. Terrorizing. Children. And. Zip-Tying. Children. And. Tear. Gassing. Children. For. Fuck's. Sake.
Have spent more time making sure the kids have their favorites for lunch than packing for my trip.
Let’s hope I didn’t forget to pack something important…
Let’s hope I didn’t forget to pack something important…
November 17, 2025 at 2:22 AM
Have spent more time making sure the kids have their favorites for lunch than packing for my trip.
Let’s hope I didn’t forget to pack something important…
Let’s hope I didn’t forget to pack something important…
Reposted by Dr. Amy Lee
Reposted by Dr. Amy Lee
📢 Our Dept. of Systems Biology at Columbia University has an open tenure-track Assistant Professor position in the broad area of quantitative biology. Come join our awesome department in NYC! Please circulate.
apply.interfolio.com/177622
Suggested deadline: 12/15/2025.
@columbiasysbio.bsky.social
apply.interfolio.com/177622
Suggested deadline: 12/15/2025.
@columbiasysbio.bsky.social
November 15, 2025 at 4:02 AM
📢 Our Dept. of Systems Biology at Columbia University has an open tenure-track Assistant Professor position in the broad area of quantitative biology. Come join our awesome department in NYC! Please circulate.
apply.interfolio.com/177622
Suggested deadline: 12/15/2025.
@columbiasysbio.bsky.social
apply.interfolio.com/177622
Suggested deadline: 12/15/2025.
@columbiasysbio.bsky.social
Reposted by Dr. Amy Lee
The Vatican returned 62 artifacts to Indigenous peoples from Canada, a historic restitution that is part of the Catholic Church's reckoning with its role in helping suppress Indigenous culture. n.pr/43T2xmD
Pope Leo returns 62 artifacts to Indigenous peoples from Canada
The Vatican returned 62 artifacts to Indigenous peoples from Canada, a historic restitution that is part of the Catholic Church's reckoning with its role in helping suppress Indigenous culture.
n.pr
November 15, 2025 at 4:31 PM
The Vatican returned 62 artifacts to Indigenous peoples from Canada, a historic restitution that is part of the Catholic Church's reckoning with its role in helping suppress Indigenous culture. n.pr/43T2xmD
Reposted by Dr. Amy Lee
Alice Wong, a writer and activist who was born with muscular dystrophy and who fought relentlessly for equal rights and access for people with disabilities, died on Friday. She was 51. nyti.ms/4r9WqEr
November 15, 2025 at 9:33 PM
Alice Wong, a writer and activist who was born with muscular dystrophy and who fought relentlessly for equal rights and access for people with disabilities, died on Friday. She was 51. nyti.ms/4r9WqEr
Reposted by Dr. Amy Lee
‘Death remains my intimate shadow partner. It has been with me since birth, always hovering close by. I understand one day we will finally waltz together into the ether. I hope when that time comes, I die with the satisfaction of a life well-lived, unapologetic, joyful, & full of love.’
—Alice Wong
—Alice Wong
November 15, 2025 at 6:12 AM
‘Death remains my intimate shadow partner. It has been with me since birth, always hovering close by. I understand one day we will finally waltz together into the ether. I hope when that time comes, I die with the satisfaction of a life well-lived, unapologetic, joyful, & full of love.’
—Alice Wong
—Alice Wong
Reposted by Dr. Amy Lee
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
November 12, 2025 at 4:49 AM
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
Reposted by Dr. Amy Lee
Canada has lost its measles elimination status...a sad milestone.
Now is the time to double down on lowering barriers to routine childhood immunizations and ensuring Canadians have access to credible, science-based information.
Link: tinyurl.com/c8nfxvk3
Now is the time to double down on lowering barriers to routine childhood immunizations and ensuring Canadians have access to credible, science-based information.
Link: tinyurl.com/c8nfxvk3
November 10, 2025 at 2:20 PM
Canada has lost its measles elimination status...a sad milestone.
Now is the time to double down on lowering barriers to routine childhood immunizations and ensuring Canadians have access to credible, science-based information.
Link: tinyurl.com/c8nfxvk3
Now is the time to double down on lowering barriers to routine childhood immunizations and ensuring Canadians have access to credible, science-based information.
Link: tinyurl.com/c8nfxvk3
Reposted by Dr. Amy Lee
It’s officially potluck season withoffice parties galore. 🦃🥘 If, like me, you harbor an irrational fear of food poisoning, I’ve got you covered. Here’s your ID doctor–approved guide to surviving the season’s buffets w/out ending up in the ER.
🧤🍽️💀
open.substack.com/pub/bktitanj...
🧤🍽️💀
open.substack.com/pub/bktitanj...
An ID Doctor’s Guide to Surviving Holiday Potlucks Food Poisoning Free
Because nothing says “festive” like avoiding an impromptu Norovirus outbreak.
open.substack.com
November 10, 2025 at 3:05 PM
It’s officially potluck season withoffice parties galore. 🦃🥘 If, like me, you harbor an irrational fear of food poisoning, I’ve got you covered. Here’s your ID doctor–approved guide to surviving the season’s buffets w/out ending up in the ER.
🧤🍽️💀
open.substack.com/pub/bktitanj...
🧤🍽️💀
open.substack.com/pub/bktitanj...
Reposted by Dr. Amy Lee
NEWS — FDA announces 13 cases of infant botulism across 10 states after babies were given ByHeart powder formula from two specific lots.
Outbreak Investigation of Infant Botulism: Infant Formula
Do not use certain lots of ByHeart Whole Nutrition Infant Formula. FDA’s Investigation is ongoing.
www.fda.gov
November 8, 2025 at 10:09 PM
NEWS — FDA announces 13 cases of infant botulism across 10 states after babies were given ByHeart powder formula from two specific lots.