Matthijs Dorst
@mattneuro.dorst-lab.org
Neuroscientist in Oslo. Former Editor. Mucking about with Voltage Imaging and patching. Aiming for a mix of fun, science, and funny science. Trying to be kind. He/him. https://dorst-lab.org/
Reposted by Matthijs Dorst
Macrobild av några små murgröneblad med kanterna klädda i taggiga frostkristaller.
November 23, 2025 at 7:48 AM
Macrobild av några små murgröneblad med kanterna klädda i taggiga frostkristaller.
If you think you're having a bad day: I just emailed someone to congratulate them with publishing a cool paper on a niche topic they've been working on for years, only to realize moments later that the paper was actually by someone with the same first name but different last name.
a cardboard box with the words box of shame painted on it
Alt: a cardboard box with the words box of shame painted on it
media.tenor.com
November 21, 2025 at 3:46 PM
If you think you're having a bad day: I just emailed someone to congratulate them with publishing a cool paper on a niche topic they've been working on for years, only to realize moments later that the paper was actually by someone with the same first name but different last name.
Me, a cool neuroscientist, wondering what the two smelly nerds are fighting over
#chemchat
i need your best inorganic memes. Go
i need your best inorganic memes. Go
November 19, 2025 at 1:11 AM
Me, a cool neuroscientist, wondering what the two smelly nerds are fighting over
For those of you keeping score at home: that is now 3 times Helthjem as attempted to deliver the same package to me, forgetting to actually bring it along each time.
Mail delivery in Norway and Sweden is truly comically bad.
Mail delivery in Norway and Sweden is truly comically bad.
November 18, 2025 at 11:18 AM
For those of you keeping score at home: that is now 3 times Helthjem as attempted to deliver the same package to me, forgetting to actually bring it along each time.
Mail delivery in Norway and Sweden is truly comically bad.
Mail delivery in Norway and Sweden is truly comically bad.
Past me: "I am going to cable-manage this setup properly, not let it devolve into a tangled mess of cable-spaghetti!"
Current me: *quiet sobbing*
Current me: *quiet sobbing*
November 17, 2025 at 2:30 PM
Past me: "I am going to cable-manage this setup properly, not let it devolve into a tangled mess of cable-spaghetti!"
Current me: *quiet sobbing*
Current me: *quiet sobbing*
Reposted by Matthijs Dorst
Axonal pathfinding of zebrafish retinal ganglion cells forms the optic nerve. Credit to Dr. Matthew Bostock @houartlab.bsky.social. #ZebrafishZunday 🧪
November 16, 2025 at 8:30 PM
Axonal pathfinding of zebrafish retinal ganglion cells forms the optic nerve. Credit to Dr. Matthew Bostock @houartlab.bsky.social. #ZebrafishZunday 🧪
Reposted by Matthijs Dorst
🔔 Nominations for the 2026 #ALBA-#FKNE Diversity Prize are now open!
Highlight scientists driving progress in diversity, equity and inclusion in #BrainResearch. 🧠
🗓️ Submit your nominations by 8 January 2026
👉 https://loom.ly/IbLJuVQ
Highlight scientists driving progress in diversity, equity and inclusion in #BrainResearch. 🧠
🗓️ Submit your nominations by 8 January 2026
👉 https://loom.ly/IbLJuVQ
November 14, 2025 at 10:30 AM
🔔 Nominations for the 2026 #ALBA-#FKNE Diversity Prize are now open!
Highlight scientists driving progress in diversity, equity and inclusion in #BrainResearch. 🧠
🗓️ Submit your nominations by 8 January 2026
👉 https://loom.ly/IbLJuVQ
Highlight scientists driving progress in diversity, equity and inclusion in #BrainResearch. 🧠
🗓️ Submit your nominations by 8 January 2026
👉 https://loom.ly/IbLJuVQ
"Nah, I won't need to bring my notebook, I just need to take this one measurement"
November 13, 2025 at 4:44 PM
"Nah, I won't need to bring my notebook, I just need to take this one measurement"
Reposted by Matthijs Dorst
✨ New preprint ✨ What if we could watch AND control thousands of individual neurons in behaving mice—with stable access over months? 🧠⚡ Our work introduces transgenic all-optical tools that make this possible - and a resulting surprising discovery! 🔭💡
www.biorxiv.org/content/10.1... 1/13 🧵
www.biorxiv.org/content/10.1... 1/13 🧵
Large-scale cellular-resolution read/write of activity enables discovery of cell types defined by complex circuit properties
The complexity of the mammalian brain’s vast population of interconnected neurons poses a formidable challenge to elucidate its underlying mechanisms of coordination and computation. A key step forwar...
www.biorxiv.org
November 13, 2025 at 12:24 AM
✨ New preprint ✨ What if we could watch AND control thousands of individual neurons in behaving mice—with stable access over months? 🧠⚡ Our work introduces transgenic all-optical tools that make this possible - and a resulting surprising discovery! 🔭💡
www.biorxiv.org/content/10.1... 1/13 🧵
www.biorxiv.org/content/10.1... 1/13 🧵
Reposted by Matthijs Dorst
Our red calcium indicator, FRCaMPi, and its soma-localized version, SomaFRCaMPi, are now available from @addgene.bsky.social in various vectors, along with all the sensors used for benchmarking. www.addgene.org/browse/artic...
November 12, 2025 at 12:08 AM
Our red calcium indicator, FRCaMPi, and its soma-localized version, SomaFRCaMPi, are now available from @addgene.bsky.social in various vectors, along with all the sensors used for benchmarking. www.addgene.org/browse/artic...
Apropos of nothing, what is the mood regarding 🧠 #SfN this year? Are people choosing not to travel to the USA? Or are we expecting little change from last year?
#neuroskyence
#neuroskyence
November 11, 2025 at 12:51 PM
Apropos of nothing, what is the mood regarding 🧠 #SfN this year? Are people choosing not to travel to the USA? Or are we expecting little change from last year?
#neuroskyence
#neuroskyence
Finally figured out why this lick-port circuit was not working: some absolute idiot mixed up the orientation of a relay on the schematic!
(it was me, I made the schematic)
(it was me, I made the schematic)
November 10, 2025 at 1:48 PM
Finally figured out why this lick-port circuit was not working: some absolute idiot mixed up the orientation of a relay on the schematic!
(it was me, I made the schematic)
(it was me, I made the schematic)
Reposted by Matthijs Dorst
AAVs are crucial vectors for delivering biosensors into neurons! Using AAV delivery, we perform two-color imaging of calcium and potassium transients in neurons. These AAVs are now available from @braincase.bsky.social www.ebraincase.com/news/new-pro...
November 6, 2025 at 10:15 AM
AAVs are crucial vectors for delivering biosensors into neurons! Using AAV delivery, we perform two-color imaging of calcium and potassium transients in neurons. These AAVs are now available from @braincase.bsky.social www.ebraincase.com/news/new-pro...
For anyone wondering: if you need to send a bunch of analog signals around a setup, you can totally misuse ethernet for an easy plug-and-play connection.
I've somehow managed to already use all 8 wires for this one, so please, nobody give me any more experiment ideas.
I've somehow managed to already use all 8 wires for this one, so please, nobody give me any more experiment ideas.
November 5, 2025 at 2:36 PM
For anyone wondering: if you need to send a bunch of analog signals around a setup, you can totally misuse ethernet for an easy plug-and-play connection.
I've somehow managed to already use all 8 wires for this one, so please, nobody give me any more experiment ideas.
I've somehow managed to already use all 8 wires for this one, so please, nobody give me any more experiment ideas.
Considering how much I have been using other people's 3D printers over the years, this was probably inevitable
November 5, 2025 at 12:04 PM
Considering how much I have been using other people's 3D printers over the years, this was probably inevitable
Also, do you *really* need 50+ pages of details for that initial selection? Is it *really* going to come down to which of the candidates wrote a better lab-leadership philosophy statement, just for that first round?
Anyone outside academia would consider our hiring process to be completely bonkers.
Anyone outside academia would consider our hiring process to be completely bonkers.
The academic job market is doing something very good:
A lot of searches are *NO* longer asking for reference letters until applicants make the short list.
This makes is easier to apply for jobs, reduces the letter writing load for faculty, and makes the review process easier for committee members.
A lot of searches are *NO* longer asking for reference letters until applicants make the short list.
This makes is easier to apply for jobs, reduces the letter writing load for faculty, and makes the review process easier for committee members.
Dear academics
We could dramatically reduce our administrative workload if we all just agreed not to ask for reference letters until we made our list of finalists.
This is massive collective action problem has already been solved by…
*checks notes*
…every other industry on earth.
We could dramatically reduce our administrative workload if we all just agreed not to ask for reference letters until we made our list of finalists.
This is massive collective action problem has already been solved by…
*checks notes*
…every other industry on earth.
November 5, 2025 at 12:47 AM
Also, do you *really* need 50+ pages of details for that initial selection? Is it *really* going to come down to which of the candidates wrote a better lab-leadership philosophy statement, just for that first round?
Anyone outside academia would consider our hiring process to be completely bonkers.
Anyone outside academia would consider our hiring process to be completely bonkers.
Reposted by Matthijs Dorst
Open Sesame!
The ELT doors have moved for the first time. This was no small feat, as each door will weigh 650 tonnes once completed.
The ELT dome & its doors will guard the telescope from the harsh conditions of the Atacama Desert.
https://www.eso.org/public/videos/potw2544a/
🔭 🧪
📹 ESO/ACe
The ELT doors have moved for the first time. This was no small feat, as each door will weigh 650 tonnes once completed.
The ELT dome & its doors will guard the telescope from the harsh conditions of the Atacama Desert.
https://www.eso.org/public/videos/potw2544a/
🔭 🧪
📹 ESO/ACe
November 3, 2025 at 8:02 AM
Open Sesame!
The ELT doors have moved for the first time. This was no small feat, as each door will weigh 650 tonnes once completed.
The ELT dome & its doors will guard the telescope from the harsh conditions of the Atacama Desert.
https://www.eso.org/public/videos/potw2544a/
🔭 🧪
📹 ESO/ACe
The ELT doors have moved for the first time. This was no small feat, as each door will weigh 650 tonnes once completed.
The ELT dome & its doors will guard the telescope from the harsh conditions of the Atacama Desert.
https://www.eso.org/public/videos/potw2544a/
🔭 🧪
📹 ESO/ACe
Today is a good day to visit the National History museum in Oslo! Especially since university employees get free access 😎
November 2, 2025 at 2:28 PM
Today is a good day to visit the National History museum in Oslo! Especially since university employees get free access 😎
Strong opening by @mohebial.bsky.social for today's @swebags.bsky.social seminar!
October 30, 2025 at 3:09 PM
Strong opening by @mohebial.bsky.social for today's @swebags.bsky.social seminar!
Reposted by Matthijs Dorst
New story up on the non-existent banned words from NIH grants (based on my grant title, word cloud analysis)
www.statnews.com/2025/10/29/n...
1/3
www.statnews.com/2025/10/29/n...
1/3
Scientists had to change more than 700 grant titles to receive NIH funding. Health disparities researchers fear what’s next
The titles of more than 700 multi-year NIH grants have been changed this year, according to an analysis by Jeremy Berg, a former agency official
www.statnews.com
October 29, 2025 at 12:07 PM
New story up on the non-existent banned words from NIH grants (based on my grant title, word cloud analysis)
www.statnews.com/2025/10/29/n...
1/3
www.statnews.com/2025/10/29/n...
1/3
Reposted by Matthijs Dorst
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Quick Check Needed
mrc.tal.net
October 29, 2025 at 9:17 AM
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Reposted by Matthijs Dorst
It's been a long, long, LONG wait, but the Portrait in Cells scarf - based on this artwork - is back in stock in two weights of silk, yayyyyy! #sciart www.etsy.com/shop/artolog...
October 21, 2025 at 9:00 PM
It's been a long, long, LONG wait, but the Portrait in Cells scarf - based on this artwork - is back in stock in two weights of silk, yayyyyy! #sciart www.etsy.com/shop/artolog...
Taking precautions after that last AWS outage
October 28, 2025 at 12:25 PM
Taking precautions after that last AWS outage
Reposted by Matthijs Dorst
Normalize replying to manuscript reviewers' comments with emojis.
October 27, 2025 at 1:53 PM
Normalize replying to manuscript reviewers' comments with emojis.