Mattia Laffranchi
mattia-laffranchi.bsky.social
Mattia Laffranchi
@mattia-laffranchi.bsky.social
Fixed-term researcher at University of Rome La Sapienza | Immunity, cancer, and the space in between.
Check out:

Increased co-expression of ICOS and PD-1 predicts poor overall survival in patients with acute myeloid leukemia

doi.org/10.1016/j.im...

High expression of ICOS was associated with poor outcomes in AML patients, with implications for novel AML therapies

#leukemia #ICB #immunobiology
November 18, 2025 at 10:30 AM
Check out:

Altered serum concentrations of IL-8, IL-32 and IL-10 in patients with lung impairment 6 months after COVID-19

doi.org/10.1016/j.im...

Serum IL-32, IL-8, and IL-10 levels are associated to lung sequelae after COVID-19.

#COVID-19 #cytokine #immunology #immunobiology
November 6, 2025 at 10:04 AM
Still relevant in Immunology:

Macrophages: Their role, activation and polarization in pulmonary diseases
www.sciencedirect.com/science/arti...

Key points:
The diverse functions of lung macrophages are attributable to their plasticity

#Macrophage #Immunology #Immunobiology #Elsevier
October 25, 2025 at 1:37 PM
Check out our latest review on dendritic cells and their roles in cancer immune responses on Cellular & Molecular Immunology:

"Dendritic cell subsets in cancer immunity and tumor antigen sensing"
doi.org/10.1038/s414...

#science #immunology #review #dendriticcell #DC #immunesystem #cancer
October 22, 2025 at 11:49 AM
Check out:

Single-cell transcriptome analysis of macrophage subpopulations contributing to chemotherapy resistance in ovarian cancer
Key points:
macrophaged increased their frequency post-chemotherapy in ovarian cancers

www.sciencedirect.com/science/arti...
#Immunology #Immunobiology #Elsevier
September 30, 2025 at 1:11 PM
Still relevant in Immunology:

Natural and trained innate immunity against Mycobacterium tuberculosis
www.sciencedirect.com/science/arti...

Key points:
M. Tuberculosis and BCG vaccine creates trained immune memory via TLR7/9 signaling.

#Tubercolosis #Vaccine #Immunology #Immunobiology #Elsevier
September 26, 2025 at 11:53 AM
Check out one of our latest review on Chemerin (RARRES2) and it's roles in the regulation of immune responses on Journal of Leukocyte Biology.

doi.org/10.1093/jleu...

#science #immunology #review #chemerin #immunesystem
September 18, 2025 at 2:09 PM
Still relevant in Immunology:

Human macrophage polarization in vitro: Maturation and activation methods compared

Key points:
Macrophage polarization is highly dependent on environmental factors.

www.sciencedirect.com/science/arti...

#Science #Immunology #Macrophage #Immunobiology #Elsevier
September 15, 2025 at 8:12 PM