Marta Barisa
@marta-barisa.bsky.social
Solid tumour immunotherapy @ UCL
Great Ormond Street Hospital for Children, London, UK
Great Ormond Street Hospital for Children, London, UK
Reposted by Marta Barisa
Excited to share our new paper: ‘Phenoscaping Reveals Multimodal γδ T-cell Cytotoxicity as a Strategy to Overcome Cancer Cell–Mediated Immunomodulation’ led by Callum Nattress in collab. with Jonathan Fisher lab (1/13)
aacrjournals.org/cancerres/ar...
aacrjournals.org/cancerres/ar...
October 14, 2025 at 5:07 PM
Excited to share our new paper: ‘Phenoscaping Reveals Multimodal γδ T-cell Cytotoxicity as a Strategy to Overcome Cancer Cell–Mediated Immunomodulation’ led by Callum Nattress in collab. with Jonathan Fisher lab (1/13)
aacrjournals.org/cancerres/ar...
aacrjournals.org/cancerres/ar...
Reposted by Marta Barisa
This year’s #NobelPrize in Physiology or Medicine has been awarded to three scientists for discovering how the immune system distinguishes friend from foe. https://scim.ag/3Wt5rdi
Medicine Nobel goes to three researchers who identified immune system’s security guards
Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease
scim.ag
October 6, 2025 at 1:45 PM
This year’s #NobelPrize in Physiology or Medicine has been awarded to three scientists for discovering how the immune system distinguishes friend from foe. https://scim.ag/3Wt5rdi
Reposted by Marta Barisa
🏆Announcing our Development Fund 2025 Awardees 🏆 This pump-priming fund enables researchers to explore and launch innovative new ideas. Swipe to see our first four successful applicants and read about all the projects and co-applicants on our website: www.colcc.ac.uk/development-...
September 25, 2025 at 11:47 AM
🏆Announcing our Development Fund 2025 Awardees 🏆 This pump-priming fund enables researchers to explore and launch innovative new ideas. Swipe to see our first four successful applicants and read about all the projects and co-applicants on our website: www.colcc.ac.uk/development-...
Reposted by Marta Barisa
Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for antigen-dim cell targeting & avoidance of antigen-dim tumor relapse
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
August 6, 2025 at 5:19 PM
Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for antigen-dim cell targeting & avoidance of antigen-dim tumor relapse
@natcomms.nature.com
www.nature.com/articles/s41...
@natcomms.nature.com
www.nature.com/articles/s41...
👩🔬 Check out the stunning AI-analysed videos of aB7H3 CAR-T killing clumps of patient-derived neuroblastoma generated by our colleagues Prinses Maxima
🔬 CD4 CAR (blue), CD8 CAR (green), live tumours (yellow), dead tumours (red)
Full story nature.com/articles/s41...
@natureportfolio.nature.com
🔬 CD4 CAR (blue), CD8 CAR (green), live tumours (yellow), dead tumours (red)
Full story nature.com/articles/s41...
@natureportfolio.nature.com
August 8, 2025 at 7:19 AM
👩🔬 Check out the stunning AI-analysed videos of aB7H3 CAR-T killing clumps of patient-derived neuroblastoma generated by our colleagues Prinses Maxima
🔬 CD4 CAR (blue), CD8 CAR (green), live tumours (yellow), dead tumours (red)
Full story nature.com/articles/s41...
@natureportfolio.nature.com
🔬 CD4 CAR (blue), CD8 CAR (green), live tumours (yellow), dead tumours (red)
Full story nature.com/articles/s41...
@natureportfolio.nature.com
🚨 Avidity of clinical-stage aB7H3 scFv CAR-T's predicts function 🚨
The conclusions took us by surprise, in the opposite direction of canonically held knowledge about CD19- CARs in leukaemia
Check out our latest story in
@natureportfolio.nature.com
www.nature.com/articles/s41...
The conclusions took us by surprise, in the opposite direction of canonically held knowledge about CD19- CARs in leukaemia
Check out our latest story in
@natureportfolio.nature.com
www.nature.com/articles/s41...
Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function - Nature Communications
CAR-T cells have been found to be less effective as treatment for solid tumours. Here the authors, utilising B7H3 as an antigen, consider how changes in B7H3 binders lead to functional changes of CAR-...
www.nature.com
August 8, 2025 at 7:12 AM
🚨 Avidity of clinical-stage aB7H3 scFv CAR-T's predicts function 🚨
The conclusions took us by surprise, in the opposite direction of canonically held knowledge about CD19- CARs in leukaemia
Check out our latest story in
@natureportfolio.nature.com
www.nature.com/articles/s41...
The conclusions took us by surprise, in the opposite direction of canonically held knowledge about CD19- CARs in leukaemia
Check out our latest story in
@natureportfolio.nature.com
www.nature.com/articles/s41...
🌟 I’ve written a children’s book about vaccines- probably the greatest ever paediatric health innovation.
I struggled to find resources to explain this to my son that were accessible to him, so I wrote my own.
Everyone is welcome to our story time! 🔬
You can find the book here: amzn.eu/d/3QNB5Xh.
I struggled to find resources to explain this to my son that were accessible to him, so I wrote my own.
Everyone is welcome to our story time! 🔬
You can find the book here: amzn.eu/d/3QNB5Xh.
April 23, 2025 at 5:08 PM
🌟 I’ve written a children’s book about vaccines- probably the greatest ever paediatric health innovation.
I struggled to find resources to explain this to my son that were accessible to him, so I wrote my own.
Everyone is welcome to our story time! 🔬
You can find the book here: amzn.eu/d/3QNB5Xh.
I struggled to find resources to explain this to my son that were accessible to him, so I wrote my own.
Everyone is welcome to our story time! 🔬
You can find the book here: amzn.eu/d/3QNB5Xh.
🚨🔬 Happy to share our review out in Nat Biotech
Great collab on Mϕ, γδT and NK cell translational success (and fails) with colleagues from Harvard&Zhejiang.
What can we learn from innate immune tx trials, how can we do better and what next for the field?
www.nature.com/articles/s41587-025-02629-5
Great collab on Mϕ, γδT and NK cell translational success (and fails) with colleagues from Harvard&Zhejiang.
What can we learn from innate immune tx trials, how can we do better and what next for the field?
www.nature.com/articles/s41587-025-02629-5
Engineering innate immune cells for cancer immunotherapy - Nature Biotechnology
The unique attributes of innate immune cells position them as attractive candidates for cancer immunotherapy, with engineering strategies to enhance their antitumor potential, offering notable therape...
www.nature.com
April 16, 2025 at 1:48 PM
🚨🔬 Happy to share our review out in Nat Biotech
Great collab on Mϕ, γδT and NK cell translational success (and fails) with colleagues from Harvard&Zhejiang.
What can we learn from innate immune tx trials, how can we do better and what next for the field?
www.nature.com/articles/s41587-025-02629-5
Great collab on Mϕ, γδT and NK cell translational success (and fails) with colleagues from Harvard&Zhejiang.
What can we learn from innate immune tx trials, how can we do better and what next for the field?
www.nature.com/articles/s41587-025-02629-5