Mark Fortner
@markfortner.bsky.social
CEO @ https://aspen.bio, bioinformatics, cheminformatics, cancer research, AI in Drug Discovery, Research Project & Portfolio Management, FAIR data, semantic web, web components, java, groovy, genomics, proteomics, DEL, TPDs, Pancreatic Cancer
Pinned
Digital Transformation with Robot Monkeys
YouTube video by Aspen Biosciences
youtu.be
Does your #DrugDiscovery strategy feel like... AI-fueled robot monkeys hammering away and hoping for a miracle? 🐒🤖
The race for funding is real, but chaos isn't a plan. It's time to swap the monkeys for a real #DigitalTransformation roadmap.
youtu.be/R0n__5HOOe8?...
The race for funding is real, but chaos isn't a plan. It's time to swap the monkeys for a real #DigitalTransformation roadmap.
youtu.be/R0n__5HOOe8?...
Reposted by Mark Fortner
November 15, 2025 at 4:03 PM
Computational deep dive reveals hidden #cancer drug targets and repurposing opportunities
Computational deep dive reveals hidden cancer drug targets and repurposing opportunities
One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology...
share.google
November 15, 2025 at 6:53 PM
Computational deep dive reveals hidden #cancer drug targets and repurposing opportunities
Reposted by Mark Fortner
Cartesian Therapeutics will pause lupus work despite early success, shifting focus to myositis and myasthenia gravis as it advances its cell therapy.
endpoints.news/cartesian-to...
endpoints.news/cartesian-to...
Despite positive data, Cartesian to pause work in form of lupus in favor of other indications
Cartesian Therapeutics said it will focus development of its lead cell therapy candidate on patients with myasthenia gravis and myositis, and will pause work in systemic lupus erythematosus.
endpoints.news
November 14, 2025 at 9:06 PM
Cartesian Therapeutics will pause lupus work despite early success, shifting focus to myositis and myasthenia gravis as it advances its cell therapy.
endpoints.news/cartesian-to...
endpoints.news/cartesian-to...
Reposted by Mark Fortner
Reposted by Mark Fortner
Richard so deserves this - a legend in bioinformatics and computational biology - work genome, human genome, Pfam, 1,000 genomes, Sam/bam format, bwa, vcf, psmc… and so many more
Congratulations to Richard Durbin on being awarded our Genetics Society Medal!
November 14, 2025 at 1:37 PM
Richard so deserves this - a legend in bioinformatics and computational biology - work genome, human genome, Pfam, 1,000 genomes, Sam/bam format, bwa, vcf, psmc… and so many more
Reposted by Mark Fortner
A bright white dahlia to freshen up your Friday 🤍
#Flowers #Dahlias #Bloomscrolling #FridayFlowers #FloralFriday #Photography #FlowerScape #Scape #White
#Flowers #Dahlias #Bloomscrolling #FridayFlowers #FloralFriday #Photography #FlowerScape #Scape #White
November 14, 2025 at 1:19 PM
A bright white dahlia to freshen up your Friday 🤍
#Flowers #Dahlias #Bloomscrolling #FridayFlowers #FloralFriday #Photography #FlowerScape #Scape #White
#Flowers #Dahlias #Bloomscrolling #FridayFlowers #FloralFriday #Photography #FlowerScape #Scape #White
Reposted by Mark Fortner
Begging people to take mythology classes
This is a real flight school, teaching people to fly planes!!! Like????
November 14, 2025 at 12:48 AM
Begging people to take mythology classes
Reposted by Mark Fortner
Do you want to learn about the value of good data management? Join our guest speakers for the third ChemSpider webinar in a new series where they will share their thoughts about data management, which tools to use, what standards to follow and how to get everyone involved. Register ▶️ rsc.li/3X1Ouag
November 14, 2025 at 3:48 PM
Do you want to learn about the value of good data management? Join our guest speakers for the third ChemSpider webinar in a new series where they will share their thoughts about data management, which tools to use, what standards to follow and how to get everyone involved. Register ▶️ rsc.li/3X1Ouag
Reposted by Mark Fortner
Preprint alert: 🧠🌊🦓-🐟
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Advection versus diffusion in brain ventricular transport
Cerebrospinal fluid (CSF) is integral to brain function. CSF provides mechanical support for the brain and helps distribute nutrients, neurotransmitters and metabolites throughout the central nervous ...
www.biorxiv.org
May 2, 2025 at 7:18 AM
Preprint alert: 🧠🌊🦓-🐟
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Reposted by Mark Fortner
How can large language models (LLMs) & #KnowledgeGraphs work together to make complex data more accessible?
#GRAPHIA’s Matteo Romanello, Luca De Santis & Yann Pomie explore interfaces using #LLMs to query structured data in plain language.
🎥 www.youtube.com/watch?v=Ch8a...
#AI #OpenScience #SSHData
#GRAPHIA’s Matteo Romanello, Luca De Santis & Yann Pomie explore interfaces using #LLMs to query structured data in plain language.
🎥 www.youtube.com/watch?v=Ch8a...
#AI #OpenScience #SSHData
Day 3 Language as an Interface
YouTube video by GRAPHIA Project
www.youtube.com
November 11, 2025 at 9:13 AM
How can large language models (LLMs) & #KnowledgeGraphs work together to make complex data more accessible?
#GRAPHIA’s Matteo Romanello, Luca De Santis & Yann Pomie explore interfaces using #LLMs to query structured data in plain language.
🎥 www.youtube.com/watch?v=Ch8a...
#AI #OpenScience #SSHData
#GRAPHIA’s Matteo Romanello, Luca De Santis & Yann Pomie explore interfaces using #LLMs to query structured data in plain language.
🎥 www.youtube.com/watch?v=Ch8a...
#AI #OpenScience #SSHData
Stanford Medicine scientists tie lupus to a virus nearly all of us carry
Stanford Medicine scientists tie lupus to a virus nearly all of us carry
The Epstein-Barr virus can convert B cells it’s infected into diabolical overlords that reprogram myriad other immune cells to attack our tissues, Stanford Medicine scientists have found.
med.stanford.edu
November 14, 2025 at 1:08 AM
Stanford Medicine scientists tie lupus to a virus nearly all of us carry
Reposted by Mark Fortner
The recent openRxiv meeting was a chance to present a vision for the future: a network of organizations working together to improve science communication and an ‘article of the future’ that is a constellation of linked web objects.
openrxiv.org/openrxiv-day/
openrxiv.org/openrxiv-day/
November 13, 2025 at 7:14 PM
The recent openRxiv meeting was a chance to present a vision for the future: a network of organizations working together to improve science communication and an ‘article of the future’ that is a constellation of linked web objects.
openrxiv.org/openrxiv-day/
openrxiv.org/openrxiv-day/
Reposted by Mark Fortner
For #redWednesday, a dahlia from the San Francisco Conservatory of Flower's dahlia garden with a tiny pollinator.
#dahlia #flowers #nature #bloomscrolling #pollinators #gardens #naturephotography #photography
#dahlia #flowers #nature #bloomscrolling #pollinators #gardens #naturephotography #photography
November 12, 2025 at 11:48 PM
For #redWednesday, a dahlia from the San Francisco Conservatory of Flower's dahlia garden with a tiny pollinator.
#dahlia #flowers #nature #bloomscrolling #pollinators #gardens #naturephotography #photography
#dahlia #flowers #nature #bloomscrolling #pollinators #gardens #naturephotography #photography
Reposted by Mark Fortner
Bindwell applies AI drug discovery techniques to invent new pesticide molecules.
Teen founders raise $6M to reinvent pesticides using AI — and convince Paul Graham to join in | TechCrunch
Bindwell applies AI drug discovery techniques to invent new pesticide molecules.
techcrunch.com
November 13, 2025 at 3:04 PM
Bindwell applies AI drug discovery techniques to invent new pesticide molecules.
Reposted by Mark Fortner
It’s all coming in time for the holidays to allegedly make your gifting more convenient (and also conveniently ensure that Google gets a piece of the action).
Google is rolling out conversational shopping—and ads—in AI Mode search
Conversational shopping is Google’s first big swing at monetizing AI Mode search.
arstechnica.com
November 13, 2025 at 8:03 PM
It’s all coming in time for the holidays to allegedly make your gifting more convenient (and also conveniently ensure that Google gets a piece of the action).
Reposted by Mark Fortner
mRNA vaccines help vs cancer
Our @scifri.bsky.social conversation, with transcript
www.sciencefriday.com/segments/cov...
Remarkable improved survival data and mechanism reviewed here erictopol.substack.com/p/how-mrna-v...
Our @scifri.bsky.social conversation, with transcript
www.sciencefriday.com/segments/cov...
Remarkable improved survival data and mechanism reviewed here erictopol.substack.com/p/how-mrna-v...
Study Finds COVID mRNA Vaccines Boost Cancer Treatment
New research found that mRNA vaccines for COVID-19 could enhance cancer treatments and help patients live longer.
www.sciencefriday.com
November 12, 2025 at 5:42 PM
mRNA vaccines help vs cancer
Our @scifri.bsky.social conversation, with transcript
www.sciencefriday.com/segments/cov...
Remarkable improved survival data and mechanism reviewed here erictopol.substack.com/p/how-mrna-v...
Our @scifri.bsky.social conversation, with transcript
www.sciencefriday.com/segments/cov...
Remarkable improved survival data and mechanism reviewed here erictopol.substack.com/p/how-mrna-v...
Reposted by Mark Fortner
Early findings indicate that Epstein-Barr Virus may also cause the autoimmune disease lupus
The Virus That Causes Mono May Also Cause Lupus
Early findings indicate that Epstein-Barr Virus may also cause the autoimmune disease lupus
www.scientificamerican.com
November 12, 2025 at 7:20 PM
Early findings indicate that Epstein-Barr Virus may also cause the autoimmune disease lupus
Ken Parker, Who Reinvented the Guitar, Is Dead at 73 | Just in case your collection is incomplete. @gilman.bsky.social
Ken Parker, Who Reinvented the Guitar, Is Dead at 73
www.nytimes.com
November 12, 2025 at 8:55 PM
Ken Parker, Who Reinvented the Guitar, Is Dead at 73 | Just in case your collection is incomplete. @gilman.bsky.social
Reposted by Mark Fortner
Big Tech is plotting a $100M lobbying and campaign spending blitz to block AI regulation at the state and federal level.
We must stop this takeover before it's too late.
We must stop this takeover before it's too late.
November 11, 2025 at 3:11 PM
Big Tech is plotting a $100M lobbying and campaign spending blitz to block AI regulation at the state and federal level.
We must stop this takeover before it's too late.
We must stop this takeover before it's too late.
Reposted by Mark Fortner
AI has helped researchers design antibodies that bind to antigenic sites with atomic-level precision.
AI-designed antibodies target antigens with atomic precision
Epitope-binding proteins designed from scratch by generative AI model
www.chemistryworld.com
November 11, 2025 at 3:30 PM
AI has helped researchers design antibodies that bind to antigenic sites with atomic-level precision.
New #AI framework can uncover space physics equations in raw data
New AI framework can uncover space physics equations in raw data
Artificial intelligence (AI) systems, particularly artificial neural networks, have proved to be highly promising tools for uncovering patterns in large amounts of data that would otherwise be difficu...
phys.org
November 10, 2025 at 8:31 PM
New #AI framework can uncover space physics equations in raw data
Reposted by Mark Fortner
PyrMol: A Knowledge-Structured Pyramid Graph Framework forGeneralizable Molecular Property Prediction https://www.biorxiv.org/content/10.1101/2025.11.09.686426v1
November 10, 2025 at 2:47 PM
PyrMol: A Knowledge-Structured Pyramid Graph Framework forGeneralizable Molecular Property Prediction https://www.biorxiv.org/content/10.1101/2025.11.09.686426v1
Reposted by Mark Fortner
An experimental gene-editing treatment shows promise for permanently lowering levels of cholesterol and triglycerides, possibly helping cut the risk for heart disease. n.pr/4hPhrQp
CRISPR gene-editing works to reduce high cholesterol in a new study
An experimental gene-editing treatment shows promise for permanently lowering levels of cholesterol and triglycerides, possibly helping cut the risk for heart disease.
n.pr
November 8, 2025 at 3:51 PM
An experimental gene-editing treatment shows promise for permanently lowering levels of cholesterol and triglycerides, possibly helping cut the risk for heart disease. n.pr/4hPhrQp