Maik Bischoff
@maikbischoff.bsky.social
Junior Group Leader in Münster, Germany.
Morphogenesis, collective cell migration, cytoskeleton, cell-adhesion and self-organization/emergent behavior in #Drosophila.
Animal photos: 📷 instagram.com/maikscritters 🐸🐍
Morphogenesis, collective cell migration, cytoskeleton, cell-adhesion and self-organization/emergent behavior in #Drosophila.
Animal photos: 📷 instagram.com/maikscritters 🐸🐍
Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰
We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila.
I’ll soon hire my first #PhD student — feel free to reach out!
#juniorPI #Science #devbio
We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila.
I’ll soon hire my first #PhD student — feel free to reach out!
#juniorPI #Science #devbio
November 25, 2025 at 3:57 PM
Super proud to be part of SFB1348 — and excited to share that I now officially have my own lab in Münster! 🎉🪰
We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila.
I’ll soon hire my first #PhD student — feel free to reach out!
#juniorPI #Science #devbio
We’ll study #cellbio & #morphogenesis, focusing on organ sculpting and #chirality in #Drosophila.
I’ll soon hire my first #PhD student — feel free to reach out!
#juniorPI #Science #devbio
Ok, i think its safe to say that Chymomyza is outside the Genus "Drosophila". It just unclear if its a Sister to Drosophila or Scaptodrosophila (I find papers for both), so, I changed the tree again:
November 18, 2025 at 3:02 PM
Ok, i think its safe to say that Chymomyza is outside the Genus "Drosophila". It just unclear if its a Sister to Drosophila or Scaptodrosophila (I find papers for both), so, I changed the tree again:
I updated it a little... Chamomyza seems to be a bit unclear.
November 17, 2025 at 1:33 PM
I updated it a little... Chamomyza seems to be a bit unclear.
Hey #Drosophila evolution people, quick phylogeny question! Is this simplified tree reasonable? I integrated multiple papers & added some polytomies, so that there is nothing too speculative in there. Does it look right to you? 🪰 It's just for a presentation 😉
#Evolution #Phylogeny
#Evolution #Phylogeny
November 17, 2025 at 10:59 AM
Hey #Drosophila evolution people, quick phylogeny question! Is this simplified tree reasonable? I integrated multiple papers & added some polytomies, so that there is nothing too speculative in there. Does it look right to you? 🪰 It's just for a presentation 😉
#Evolution #Phylogeny
#Evolution #Phylogeny
My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
October 3, 2025 at 9:06 AM
My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
Leccinum spec 2
September 28, 2025 at 3:58 PM
Leccinum spec 2
September 28, 2025 at 2:38 PM
11/12
This links directly to my own research: how a mesenchymal sheet in the Drosophila testis uses directed, contact-dependent migration to generate complex forms.
This Perspective can almost serve as a mission statement for my future lab in Münster. Writing it helped me a lot sharpen my vision 😊
This links directly to my own research: how a mesenchymal sheet in the Drosophila testis uses directed, contact-dependent migration to generate complex forms.
This Perspective can almost serve as a mission statement for my future lab in Münster. Writing it helped me a lot sharpen my vision 😊
September 24, 2025 at 1:06 PM
11/12
This links directly to my own research: how a mesenchymal sheet in the Drosophila testis uses directed, contact-dependent migration to generate complex forms.
This Perspective can almost serve as a mission statement for my future lab in Münster. Writing it helped me a lot sharpen my vision 😊
This links directly to my own research: how a mesenchymal sheet in the Drosophila testis uses directed, contact-dependent migration to generate complex forms.
This Perspective can almost serve as a mission statement for my future lab in Münster. Writing it helped me a lot sharpen my vision 😊
10/12
...sculpt entire organs, as shown by the Gartner, @streichan.bsky.social , and Nelson labs. We highlight these examples and speculate on how DIRECTED, contact-based migration might also contribute to these processes.
...sculpt entire organs, as shown by the Gartner, @streichan.bsky.social , and Nelson labs. We highlight these examples and speculate on how DIRECTED, contact-based migration might also contribute to these processes.
September 24, 2025 at 1:06 PM
10/12
...sculpt entire organs, as shown by the Gartner, @streichan.bsky.social , and Nelson labs. We highlight these examples and speculate on how DIRECTED, contact-based migration might also contribute to these processes.
...sculpt entire organs, as shown by the Gartner, @streichan.bsky.social , and Nelson labs. We highlight these examples and speculate on how DIRECTED, contact-based migration might also contribute to these processes.
9/12
And this isn’t just a fringe hypothesis: eg. fish pigment cells and Xenopus neural crest cells are already known to use such mechanisms to self-pattern.
Mesenchymal collectives can even...
And this isn’t just a fringe hypothesis: eg. fish pigment cells and Xenopus neural crest cells are already known to use such mechanisms to self-pattern.
Mesenchymal collectives can even...
September 24, 2025 at 1:06 PM
9/12
And this isn’t just a fringe hypothesis: eg. fish pigment cells and Xenopus neural crest cells are already known to use such mechanisms to self-pattern.
Mesenchymal collectives can even...
And this isn’t just a fringe hypothesis: eg. fish pigment cells and Xenopus neural crest cells are already known to use such mechanisms to self-pattern.
Mesenchymal collectives can even...
8/12
...the potential for complexity. Cells can react in specific ways to eg. different cell types and use this to create PATTERNS. We propose the term “directed mesenchymal self-patterning” for this process.
Patterns can be encoded in the ways cells change their migration behaviors upon contact.
...the potential for complexity. Cells can react in specific ways to eg. different cell types and use this to create PATTERNS. We propose the term “directed mesenchymal self-patterning” for this process.
Patterns can be encoded in the ways cells change their migration behaviors upon contact.
September 24, 2025 at 1:06 PM
8/12
...the potential for complexity. Cells can react in specific ways to eg. different cell types and use this to create PATTERNS. We propose the term “directed mesenchymal self-patterning” for this process.
Patterns can be encoded in the ways cells change their migration behaviors upon contact.
...the potential for complexity. Cells can react in specific ways to eg. different cell types and use this to create PATTERNS. We propose the term “directed mesenchymal self-patterning” for this process.
Patterns can be encoded in the ways cells change their migration behaviors upon contact.
7/12
...in principle, many of these dynamics are related, even if their outcomes can differ dramatically.
Please read the Perspective for more details and comparisons 😊
But the coolest consequence of all this is...
...in principle, many of these dynamics are related, even if their outcomes can differ dramatically.
Please read the Perspective for more details and comparisons 😊
But the coolest consequence of all this is...
September 24, 2025 at 1:06 PM
7/12
...in principle, many of these dynamics are related, even if their outcomes can differ dramatically.
Please read the Perspective for more details and comparisons 😊
But the coolest consequence of all this is...
...in principle, many of these dynamics are related, even if their outcomes can differ dramatically.
Please read the Perspective for more details and comparisons 😊
But the coolest consequence of all this is...
6/12)
…that’s just one of many possible “architecture transitions.”
Think of a landscape of architecture transitions and a corresponding landscape of collective dynamics.
HOWEVER..
…that’s just one of many possible “architecture transitions.”
Think of a landscape of architecture transitions and a corresponding landscape of collective dynamics.
HOWEVER..
September 24, 2025 at 1:06 PM
6/12)
…that’s just one of many possible “architecture transitions.”
Think of a landscape of architecture transitions and a corresponding landscape of collective dynamics.
HOWEVER..
…that’s just one of many possible “architecture transitions.”
Think of a landscape of architecture transitions and a corresponding landscape of collective dynamics.
HOWEVER..
5/12
... that they can REPROGRAM each other: even brief contacts can trigger architectural changes and thus cause coordinated swarm-like behaviors.
A classic example is contact inhibition of locomotion (CIL), BUT…
... that they can REPROGRAM each other: even brief contacts can trigger architectural changes and thus cause coordinated swarm-like behaviors.
A classic example is contact inhibition of locomotion (CIL), BUT…
September 24, 2025 at 1:06 PM
5/12
... that they can REPROGRAM each other: even brief contacts can trigger architectural changes and thus cause coordinated swarm-like behaviors.
A classic example is contact inhibition of locomotion (CIL), BUT…
... that they can REPROGRAM each other: even brief contacts can trigger architectural changes and thus cause coordinated swarm-like behaviors.
A classic example is contact inhibition of locomotion (CIL), BUT…
4/12
... the SPATIAL ORGANIZATION of these building blocks defines single-cell behavior—e.g., lamellipodium & trailing edge positions set migration direction.
SHIFTS in this organization drive behavioral transitions.
What’s cool about cells is...
... the SPATIAL ORGANIZATION of these building blocks defines single-cell behavior—e.g., lamellipodium & trailing edge positions set migration direction.
SHIFTS in this organization drive behavioral transitions.
What’s cool about cells is...
September 24, 2025 at 1:06 PM
4/12
... the SPATIAL ORGANIZATION of these building blocks defines single-cell behavior—e.g., lamellipodium & trailing edge positions set migration direction.
SHIFTS in this organization drive behavioral transitions.
What’s cool about cells is...
... the SPATIAL ORGANIZATION of these building blocks defines single-cell behavior—e.g., lamellipodium & trailing edge positions set migration direction.
SHIFTS in this organization drive behavioral transitions.
What’s cool about cells is...
3/12
...we propose that a migrating cell is a PATCHWORK of morphodynamic building blocks, a concept dating back to Michael Abercrombie.
As a result...
...we propose that a migrating cell is a PATCHWORK of morphodynamic building blocks, a concept dating back to Michael Abercrombie.
As a result...
September 24, 2025 at 1:06 PM
3/12
...we propose that a migrating cell is a PATCHWORK of morphodynamic building blocks, a concept dating back to Michael Abercrombie.
As a result...
...we propose that a migrating cell is a PATCHWORK of morphodynamic building blocks, a concept dating back to Michael Abercrombie.
As a result...
2/12
It all started with inspiring conversations with #Drosophila legend Christiane Nüsslein-Volhard at @gfeev.bsky.social-meeting and at the Spemann-Mangold Centennial meeting—where I also first discussed the idea for this review with my great co-author @mayorlab.bsky.social.
a quick summary...
It all started with inspiring conversations with #Drosophila legend Christiane Nüsslein-Volhard at @gfeev.bsky.social-meeting and at the Spemann-Mangold Centennial meeting—where I also first discussed the idea for this review with my great co-author @mayorlab.bsky.social.
a quick summary...
September 24, 2025 at 1:06 PM
2/12
It all started with inspiring conversations with #Drosophila legend Christiane Nüsslein-Volhard at @gfeev.bsky.social-meeting and at the Spemann-Mangold Centennial meeting—where I also first discussed the idea for this review with my great co-author @mayorlab.bsky.social.
a quick summary...
It all started with inspiring conversations with #Drosophila legend Christiane Nüsslein-Volhard at @gfeev.bsky.social-meeting and at the Spemann-Mangold Centennial meeting—where I also first discussed the idea for this review with my great co-author @mayorlab.bsky.social.
a quick summary...
1/12 A very special moment for me! 🎉
My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.
rupress.org/jcb/article/...
#cellbio #devbio #science
🧵for details
My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.
rupress.org/jcb/article/...
#cellbio #devbio #science
🧵for details
September 24, 2025 at 1:06 PM
1/12 A very special moment for me! 🎉
My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.
rupress.org/jcb/article/...
#cellbio #devbio #science
🧵for details
My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.
rupress.org/jcb/article/...
#cellbio #devbio #science
🧵for details
Less than a week back in Germany - and I already found some nice cauliflower mushrooms 🍄. Yumm!
Fun fact: in german, we call them frizzy [mother] hen (krause Glucke)... 🐔
Fun fact: in german, we call them frizzy [mother] hen (krause Glucke)... 🐔
September 7, 2025 at 10:45 AM
Less than a week back in Germany - and I already found some nice cauliflower mushrooms 🍄. Yumm!
Fun fact: in german, we call them frizzy [mother] hen (krause Glucke)... 🐔
Fun fact: in german, we call them frizzy [mother] hen (krause Glucke)... 🐔
Exciting news — I am super honored to receive the 2025 MBoC Early Career Paper Award 🎉 My very first award 😊
www.molbiolcell.org/doi/10.1091/...
Couldn’t imagine a better send-off as I just wrapped up my postdoc at UNC and get ready to start a lab in Münster this fall 😃
www.molbiolcell.org/doi/10.1091/...
Couldn’t imagine a better send-off as I just wrapped up my postdoc at UNC and get ready to start a lab in Münster this fall 😃
September 1, 2025 at 10:59 AM
Exciting news — I am super honored to receive the 2025 MBoC Early Career Paper Award 🎉 My very first award 😊
www.molbiolcell.org/doi/10.1091/...
Couldn’t imagine a better send-off as I just wrapped up my postdoc at UNC and get ready to start a lab in Münster this fall 😃
www.molbiolcell.org/doi/10.1091/...
Couldn’t imagine a better send-off as I just wrapped up my postdoc at UNC and get ready to start a lab in Münster this fall 😃