Lucy Xie, PhD (she/her)
lucyxie.bsky.social
Lucy Xie, PhD (she/her)
@lucyxie.bsky.social
NIAID K99 Fellow (current) and Damon Runyon Fellow (past) in Jarosz Lab at Stanford University; PhD in Cowen Lab at University of Toronto; Interested in non-genetic mechanisms of antifungal drug resistance.
Pinned
Excited to share my postdoc work now on bioRxiv!

www.biorxiv.org/content/10.1...

We discovered a non-genetic drug-adapted state that emerges frequently in the the human fungal pathogen Candida albicans.

1/6
Stress-driven emergence of heritable non-genetic drug resistance
Drug resistance is the chief cause of treatment failure for therapies targeting chronic and infectious diseases. Whether the emergence of resistance is accelerated by environmental exposure to low lev...
www.biorxiv.org
Reposted by Lucy Xie, PhD (she/her)
Deadly #fungi are becoming drug-resistant. A new compound could beat them | Science | AAAS www.science.org/content/arti...
Deadly fungi are becoming drug-resistant. A new compound could beat them
A drug candidate with a new mechanism of action shows promise against several drug-resistant infections in mice
www.science.org
March 20, 2025 at 2:44 AM
Reposted by Lucy Xie, PhD (she/her)
This is also a valuable resource for sky users

theblue.report
The Blue Report
The top links on Bluesky over the last 24 hours. Updated hourly.
theblue.report
February 6, 2025 at 2:47 AM
Reposted by Lucy Xie, PhD (she/her)
Two new positions for group leaders working on #AMR at the Ineos Oxford Institute.
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
February 5, 2025 at 8:58 PM
Reposted by Lucy Xie, PhD (she/her)
Nearly two-thirds of antibiotics were introduced during the “golden age of antibiotics”! (short thread)
February 5, 2025 at 4:07 PM
Reposted by Lucy Xie, PhD (she/her)
🚨NEWS!

We are organising a new monthly event:

The Young Biophysicists Virtual Meetings

where early career researchers can present their work in a friendly environment. All the info and abstract submission on our website

sites.google.com/view/theoret...

Host by Divya Choudhary and Satyam Anand
February 1, 2025 at 2:33 PM
Reposted by Lucy Xie, PhD (she/her)
Reminder that @europepmc.org is a mirror of Pubmed with better search and that it indexes *all* bioRxiv preprints (as well as ResearchSquare), not just the ones funded by NIH like chauvinist Pubmed
I’m very scared to see what happens to PubMed
January 31, 2025 at 8:44 PM
Reposted by Lucy Xie, PhD (she/her)
Open call for new research groups @pasteur.fr in Paris lots of immunology themes welcome #immunosky #IDsky #Scisky 🧪🥼🔬 get in touch if you have questions
December 14, 2024 at 2:41 PM
Reposted by Lucy Xie, PhD (she/her)
New pre-print!!! What types of genes end up on plasmids and why? The take home message of this paper is that beneficial genes move from plasmids to chromosome, causing the ecological value of plasmids to decay over time.
www.biorxiv.org/content/10.1...
Chromosomal capture of beneficial genes drives plasmids towards ecological redundancy
Plasmids are a ubiquitous feature of bacterial genomes, but the evolutionary forces driving genes to become associated with plasmids are poorly understood. To address this problem, we compared the fit...
www.biorxiv.org
January 24, 2025 at 11:10 PM
Reposted by Lucy Xie, PhD (she/her)
Excited to report that Joy Bergelson (bergelsonlab.org) and I will be running a brand new GRC conference on the Function of Evolving Systems in the summer of 2026. The 2028 one will be chaired by Mikhail Tikhonov (physics.wustl.edu/people/mikha...) and @asanchezlab.bsky.social! Stay tuned!
Faculty
physics.wustl.edu
December 30, 2024 at 7:43 PM
Reposted by Lucy Xie, PhD (she/her)
Open Recruitment of a Full Professor and Head of the Department of Infectious Disease Epidemiology & Dynamics: jobs.lshtm.ac.uk/vacancy.aspx...

Good research culture, friendly colleagues, inspiring public health leaders, great connections across epi & PH, & very dedicated students.

Join!
Job Opportunity at LSHTM: Professor (and Head of Department)
The London School of Hygiene & Tropical Medicine (LSHTM) is one of the world’s leading public health universities. Our mission is to improve health and health equity in the UK and worldwide; working i...
jobs.lshtm.ac.uk
January 7, 2025 at 4:53 PM
Reposted by Lucy Xie, PhD (she/her)
Join a supportive and focussed team as an Assistant Professor (fixed term, 4 years) using OpenSAFELY to model respiratory viruses and assess socioeconomic inequality. Closes Jan 12. jobs.lshtm.ac.uk/Vacancy.aspx...
Job Opportunity at LSHTM: Assistant Professor of Infectious Disease Modelling
The London School of Hygiene & Tropical Medicine (LSHTM) is one of the world’s leading public health universities. Our mission is to improve health and health equity in the UK and worldwide; working i...
jobs.lshtm.ac.uk
January 6, 2025 at 10:37 AM
Reposted by Lucy Xie, PhD (she/her)
Yeast Genetics & Genomics at CSHL
July 22 - August 12, 2025

Application Deadline: March 31, 2025
Arrival: July 22nd by 6pm EST
Departure: August 12th around 12pm EST

For more info and to apply please visit the Yeast Genetics & Genomics course website: meetings.cshl.edu/courses.aspx...
January 17, 2025 at 2:57 PM
Reposted by Lucy Xie, PhD (she/her)
Have questions about the 2025 #HannaGrayFellows Program?

Join us for one of our informational webinar to learn more about the application process & what it means to be part of this incredible program:

Wed, 1.23.25 | 3:30–4:30PM ET

Thu, 1.30.25 | 3:30–4:30PM ET

Register today! hhmi.news/40ymhuq
January 17, 2025 at 3:15 PM
Reposted by Lucy Xie, PhD (she/her)
📢 #Yeast2025 News!
Registration and abstract submission are NOW OPEN!
Join us at the 32nd ICYGMB
📅 Save the Date: 21-24 July 2025
📍 Location: Paris @sorbonne-universite.fr
🔗 Submit: premc.org/yeast2025/su...
🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...
January 14, 2025 at 7:28 AM
Reposted by Lucy Xie, PhD (she/her)
Applications are now open for the 2025 Workshop on Molecular Evolution (MOLE) at the Marine Biological Laboratory in *beautiful* Woods Hole, MA!

More info here: molevolworkshop.github.io

Apply here: www.mbl.edu/education/ad...

Application deadline: Jan. 29th

Workshop dates: May 22nd - June 1st
Workshop on Molecular Evolution | Marine Biological Laboratory
The workshop serves graduate students, postdocs, and established faculty from around the world seeking to apply the principles of molecular evolution to questions of anthropology, conservation genetic...
www.mbl.edu
January 7, 2025 at 6:17 PM
Reposted by Lucy Xie, PhD (she/her)
Do you know a UK-based wheelchair user who works in a lab and would be willing to user-test our prototype of what is believed to be the first-ever lab coat adapted for wheelchair users?

Please share far & wide! Interest form: forms.office.com/e/66FhcQjqRT

More info: www.ucl.ac.uk/ucl-east/new...
January 7, 2025 at 2:52 PM
Reposted by Lucy Xie, PhD (she/her)
Reposted by Lucy Xie, PhD (she/her)
Happy New Year 🎉 - CanFunNet 🍁🍄 virtual meeting is back for 2025!

Mark your calendars 📆 Aug 6-8 and keep an eye out for abstract submission announcements!
January 2, 2025 at 6:00 PM
Reposted by Lucy Xie, PhD (she/her)
I understand Elon Musk is trying to get people to stop donating to Wikipedia, which reminded me that I hadn't yet made my usual annual donation to Wikipedia, so now that's been taken care of
December 26, 2024 at 9:36 PM
Reposted by Lucy Xie, PhD (she/her)
Reposted by Lucy Xie, PhD (she/her)
Kellogg Biological Station is searching for a new Director! KBS is unique in its ability to integrate lab and field research, as well as integrating fundamental research in ecology and evolution with applications to environmental problems. Questions to me or the search chairs. Please apply!
Institute/Center Director-Management - Hickory Corners, Michigan, United States
Position Summary Questions regarding this position may be directed to the Search Committee Co-Chairs, Dr. Richard Kobe ([email protected]) and Dr. Andrea Case ([email protected]). The position will remain o...
careers.msu.edu
December 12, 2024 at 3:38 PM
Reposted by Lucy Xie, PhD (she/her)
Join us in Cambridge! This evolutionary genomics professorship (lecturer/reader level) has an emphasis on introgression and gene flow. If you study any aspect of evolutionary genomics then please apply! www.jobs.cam.ac.uk/job/49389/
Associate Professor / Professor of Evolutionary Genomics - Job Opportunities - University of Cambridge
Associate Professor / Professor of Evolutionary Genomics in the Department of Genetics at the University of Cambridge.
www.jobs.cam.ac.uk
December 18, 2024 at 4:34 PM
Reposted by Lucy Xie, PhD (she/her)
Stress-driven emergence of heritable non-genetic drug resistance https://www.biorxiv.org/content/10.1101/2024.12.20.629823v1
December 22, 2024 at 7:19 AM
Excited to share my postdoc work now on bioRxiv!

www.biorxiv.org/content/10.1...

We discovered a non-genetic drug-adapted state that emerges frequently in the the human fungal pathogen Candida albicans.

1/6
Stress-driven emergence of heritable non-genetic drug resistance
Drug resistance is the chief cause of treatment failure for therapies targeting chronic and infectious diseases. Whether the emergence of resistance is accelerated by environmental exposure to low lev...
www.biorxiv.org
December 23, 2024 at 12:19 PM
Reposted by Lucy Xie, PhD (she/her)
Many academics point to bioRxiv as “the one thing improving science publishing”.

If so, the one thing you all can do is persuade colleagues to submit and make this a norm. 1/2
December 21, 2024 at 2:01 PM