Arnaud Kengmo Tchoupa
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kengmo.bsky.social
Arnaud Kengmo Tchoupa
@kengmo.bsky.social
190 followers 210 following 1 posts
Scientist (AMR, lipids, host-pathogen interactions) in Tübingen (Germany). 🇨🇲
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kengmo.bsky.social
Arnaud Kengmo Tchoupa @kengmo.bsky.social · Sep 11
Grateful to the DFG for funding our project on how Staphylococcus aureus reprograms host lipids in the context of infection and inflammation. Thanks to @andreaspeschel.bsky.social @cmfi.bsky.social and everyone supporting us!
Reposted by Arnaud Kengmo Tchoupa
henrikstrahl.bsky.social
Now properly published at @natcomms.nature.com with few additional experiments incl. demonstration of Daptomycin's ability to depolarise non-growing cells.
See the original preprint-thread for a summary of our findings.
www.nature.com/articles/s41...
#microsky
November 24, 2025 at 8:20 PM
Reposted by Arnaud Kengmo Tchoupa
leela-bg.bsky.social
Happy to see work I contributed to during my MSc at @bioscienceleeds.bsky.social with Jennifer Tomlinson’s lab out in @pnas.org! Everyone Bluesky-less except @antoncalabrese.bsky.social

www.pnas.org/doi/10.1073/...

#AMR #MRSA #NMR
Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G | PNAS
Fusidic acid (FA) is one of few remaining antibiotics active against Methicillin-resistant Staphylococcus aureus. FusB confers resistance to FA by ...
www.pnas.org
November 25, 2025 at 3:26 PM
Reposted by Arnaud Kengmo Tchoupa
simonheilbronner.bsky.social
Really happy to see the final version of this published in @isme-microbes.bsky.social. We show that production of and competition for biotin shapes S. aureus fitness in the context of nasal commensals doi.org/10.1093/isme...
Work lead by the amazing Kevser Bilici!
Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition
Abstract. The human nasal microbiome can serve as a reservoir for pathogens. In particular, the opportunistic pathogen Staphylococcus aureus can be a membe
doi.org
November 24, 2025 at 5:54 PM
Reposted by Arnaud Kengmo Tchoupa
jrossfitz.bsky.social
PhD position on bacterial (Staph aureus) transporters and host-adaptation in my group @roslininstitute.bsky.social @edinburgh-uni.bsky.social

www.findaphd.com/phds/project...
EASTBIO How do transporters promote the fitness of Staphylococcus aureus in different host-species ? at University of Edinburgh on FindAPhD.com
PhD Project - EASTBIO How do transporters promote the fitness of Staphylococcus aureus in different host-species ? at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
November 21, 2025 at 8:19 AM
Reposted by Arnaud Kengmo Tchoupa
jrossfitz.bsky.social
PhD fellowship position in my group @roslininstitute.bsky.social
@edinburgh-uni.bsky.social on Staph aureus host-pathogen interactions in atopic dermatitis using human skin organoids in collaboration with the brilliant Sara Brown.
www.findaphd.com/phds/project...
Molecular dissection of Staphylococcus aureus in Atopic Dermatitis Using a Human Skin Organoid model at University of Edinburgh on FindAPhD.com
PhD Project - Molecular dissection of Staphylococcus aureus in Atopic Dermatitis Using a Human Skin Organoid model at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
November 21, 2025 at 8:12 AM
Reposted by Arnaud Kengmo Tchoupa
vivekmutalik.bsky.social
Hmmm
This work has so many implications on literature 😳😬

Fluorescein-based dyes are not valid reporters of oxidative stress in bacteria, and conclusions based on their use must be reconsidered | PNAS www.pnas.org/doi/10.1073/...
Fluorescein-based dyes are not valid reporters of oxidative stress in bacteria, and conclusions based on their use must be reconsidered | PNAS
Dihydrodichlorofluorescein derivatives have been employed as reporters of intracellular reactive oxygen species (ROS) in innumerable studies. Their...
www.pnas.org
November 19, 2025 at 5:03 AM
Reposted by Arnaud Kengmo Tchoupa
wcratcliff.bsky.social
Let me use this as an opportunity to talk about Jordi et al's very cool paper, now out in PNAS 🧪:

pmc.ncbi.nlm.nih.gov/articles/PMC...

You can read our news and views here: www.pnas.org/doi/10.1073/...
November 13, 2025 at 4:13 PM
Reposted by Arnaud Kengmo Tchoupa
hobbslabmicro.bsky.social
📣New preprint alert! We report the alarming finding that stringent response mutations found in clinical isolates increase the frequency of donation of multiresistance plasmids in S. aureus 😱 Great team effort @microclaire.bsky.social @paulrjohnston.bsky.social

www.biorxiv.org/content/10.1...
November 13, 2025 at 12:41 PM
Reposted by Arnaud Kengmo Tchoupa
thanbichlerlab.bsky.social
📢 Postdoc position: Biochemistry & Bacterial cell biology

in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"

🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025

Please repost. #Postdoc
November 10, 2025 at 6:15 PM
Reposted by Arnaud Kengmo Tchoupa
hobbslabmicro.bsky.social
📣 Calling all senior microbiology postdocs! The University of St Andrews is inviting applications from outstanding visionary Research Fellow and Future Leader candidates to attend a Biomolecular Science Fellowship Day. Applications due by 12th Dec, see link for full details: tinyurl.com/4n3na8vn
Exciting Opportunity: Biomolecular Science Fellowship Day
The School of Biology at the University of St Andrews is inviting applications from outstanding visionary Research Fellow and Future Leader candidates to attend the Biomolecular Science (BMS) Fello…
biology.st-andrews.ac.uk
November 5, 2025 at 9:57 AM
Reposted by Arnaud Kengmo Tchoupa
thanbichlerlab.bsky.social
📢 Postdoc position: Cell Biology of Cyanobacteria

in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.

More information at shorturl.at/wNnDT (see Project 2)

🔗Apply at shorturl.at/VsEDl
📅Deadline: Nov 16, 2025

Please repost. #Postdoc
November 2, 2025 at 7:13 PM
Reposted by Arnaud Kengmo Tchoupa
henrikstrahl.bsky.social
Looking for an AMR-themed PhD project? Join us to investigate antibiotic tolerance in Staphylococcus aureus through a fully funded MRC DTP PhD studentship starting in September 2026.

This project is close collaboration with @kateduncan.bsky.social and @mycobacterium-ncl.bsky.social.
MRC DiMeN Doctoral Training Partnership: Resensitisation of antibiotic-tolerant Staphylococcus aureus small colony variants at Newcastle University on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Resensitisation of antibiotic-tolerant Staphylococcus aureus small colony variants at Newcastle University, listed on FindAPhD.com
www.findaphd.com
November 1, 2025 at 11:11 AM
Reposted by Arnaud Kengmo Tchoupa
lowlab.bsky.social
Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.

For more details and to apply please see

www.imperial.ac.uk/jobs/search-...
October 29, 2025 at 5:11 PM
Reposted by Arnaud Kengmo Tchoupa
jeremyjbarr.bsky.social
Very excited to share the latest work from our lab, which was published today in Nature!
nature.com/articles/s41...

PhD graduate and now post-doc Sofia Dahlman, along with co-senior author Sam Forster from The Hudson and other researchers from our lab and others.
Isolation, engineering and ecology of temperate phages from the human gut - Nature
Human host-associated cellular products may act as induction agents for bacteriophages.
nature.com
October 15, 2025 at 9:41 PM
Reposted by Arnaud Kengmo Tchoupa
bugsinblood.bsky.social
New review - thanks to Markus Weingarth for the invitation! www.nature.com/articles/s41...
Client Challenge
www.nature.com
October 13, 2025 at 4:36 PM
Reposted by Arnaud Kengmo Tchoupa
helmholtz-hiri.bsky.social
Looking to start your own lab? 🧬🧪 The Helmholtz Institute Würzburg (HIRI) is offering group leader positions in RNA biology, RNA medicine & RNA technology. Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
E15 Groups
The Helmholtz Institute for RNA-based Infection Researchopens a call for
www.helmholtz-hiri.de
October 13, 2025 at 1:30 PM
Reposted by Arnaud Kengmo Tchoupa
biorxiv-microbiol.bsky.social
Strain-resolved CRISPRi-Seq reveals conserved antibiotic vulnerabilities in Staphylococcus aureus https://www.biorxiv.org/content/10.1101/2025.10.13.682098v1
October 14, 2025 at 3:16 AM
Reposted by Arnaud Kengmo Tchoupa
bconlon.bsky.social
Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better www.nature.com/articles/s41...
A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics - Nature Microbiology
The authors developed a screen to find compounds that modulate intracellular Staphylococcus aureus metabolism and discovered KL1, which sensitizes persisters to antibiotics by reversing host-induced tolerance.
www.nature.com
October 10, 2025 at 1:24 PM
Reposted by Arnaud Kengmo Tchoupa
crick.ac.uk
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 2:06 PM
Reposted by Arnaud Kengmo Tchoupa
cazares-adr.bsky.social
Imagine we could travel back in time ⏪⌛️to explore the world of bacterial pathogens before humans discovered and industrialised antibiotics

We just did that to study the history of #AMR spread @science.org
doi.org/10.1126/scie...

If you like time travel & biology, this 🧵is for you👇
Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance
Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialisation of antibiotics influenced their evolution is limited by a paucity of data predati...
doi.org
October 6, 2025 at 10:42 AM
Reposted by Arnaud Kengmo Tchoupa
khadershabaana.bsky.social
Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!
October 5, 2025 at 4:10 PM
Reposted by Arnaud Kengmo Tchoupa
microbiome.bsky.social
Thinking about a postdoc in microbiome science?
Our lab at the MPI for Biology (Tübingen) builds on the culture I established at Cornell: collaborative, creative, and internationally diverse. Postdocs lead their own projects with secure funding. Join us!
#PostdocJobs #HostMicrobe #AcademicJobs
October 4, 2025 at 5:37 PM
Reposted by Arnaud Kengmo Tchoupa
erinrgreen.bsky.social
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
October 4, 2025 at 6:44 PM
Reposted by Arnaud Kengmo Tchoupa
npokorzynski.bsky.social
Please share: I'm hiring a postdoctoral scholar to investigate molecular mechanisms governing Salmonella cell envelope homeostasis inside mammalian host cells. Come join a great microbiology community @oregonstate.edu in beautiful Corvallis, OR!

Appy here: hr.oregonstate.edu/open-postdoc...
Microbiology Postdoctoral Scholar | Office of University Human Resources
hr.oregonstate.edu
October 2, 2025 at 4:22 PM
Reposted by Arnaud Kengmo Tchoupa
bugsinblood.bsky.social
Now published! www.nature.com/articles/s41...

Very nice collaboration with Hoogenboom ( @ucl.ac.uk ) and Bonev ( @uniofnottingham.bsky.social ) labs.
September 29, 2025 at 2:24 PM