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Reposted by Henrik Strahl

Natalie Bennett @nataliegreenpeer.bsky.social · 6h

#AMR - no one is safe until everyone is safe

"These bugs have long been considered to only cause infections in older babies, but are now infecting babies in their first days of life"
#AntimicrobialResistance
www.sciencealert.com/study-reveal...

Study Reveals 'Alarming' Rise of Superbugs in Newborn Babies

Humanity's war against drug-resistant microbes is not going very well.

www.sciencealert.com

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Reposted by Henrik Strahl

Dr Katherine Duncan @kateduncan.bsky.social · 6d

Very exciting to have Prof Mark Blaskovich @medicalsciencesncl.bsky.social (hosted by @henrikstrahl.bsky.social) all the way from the University of Queensland, Australia to give a seminar on collaborative approaches to combat antimicrobial resistance #drugdiscovery #AMR #antibiotics

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Reposted by Henrik Strahl

Tung Le @tunglejic.bsky.social · 9d

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

John Innes Centre @johninnescentre.bsky.social · 10d

Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...

Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre

The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…

www.jic.ac.uk

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Reposted by Henrik Strahl

Augustinas Silale @augustsilale.bsky.social · 11d

Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social

We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.

doi.org/10.1038/s415...

Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota - Nature Microbiology

Structural and functional characterization of the β-barrel assembly machinery complex in Bacteroidota reveals a distinct, seven-component complex with a large extracellular domain that may enable β-barrel–surface lipoprotein complex assembly.

doi.org

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Reposted by Henrik Strahl

Tracy Palmer @proftracypalmer.bsky.social · 8d

Check it out! A proper team effort from past and present group members and a great collaboration with @sergemostowylab.bsky.social

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 8d

The Staphylococcus aureus LXG-domain toxins EsxX and SAR0287 do not promote virulence in a zebrafish larval infection model https://www.biorxiv.org/content/10.1101/2025.10.04.680436v1

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Reposted by Henrik Strahl

Jan-Willem Veening @veeninglab.com · 9d

Also see the accompanying paper from Carol Gross' lab that used a similar approach for Bacillus subtilis: www.cell.com/cell-systems...

Comprehensive genetic interaction analysis of the Bacillus subtilis envelope using double-CRISPRi

Koo et al. apply genome-scale double-CRISPRi to map cell envelope gene interactions in Bacillus subtilis, revealing >1,000 genetic interactions and uncovering gene networks in envelope biogenesis and ...

www.cell.com

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Reposted by Henrik Strahl

Jan-Willem Veening @veeninglab.com · 9d

Finally out, such an awesome piece of work, very proud of this one: www.cell.com/cell-systems... #MicroSky

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Rhys Grinter @rhyswg.bsky.social · 23d

The outer membrane of Gram-negative bacteria blocks many antibiotics. Our latest work reveals that L-type pyocins bypass this barrier by inactivating the BAM complex, killing Pseudomonas aeruginosa without entering the cell, providing a new blueprint for beating antibiotic resistance.

A Protein Antibiotic Inhibits the BAM Complex to Kill Without Cell Entry

Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...

www.biorxiv.org

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Reposted by Henrik Strahl

Phill Stansfeld @pstansfeld.bsky.social · Jul 7

New paper out, with a contribution from Dom Gurvic and I; led by Andy Lovering and @lalouxlab.bsky.social:
www.nature.com/articles/s41...

A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily

Nature Communications - This study reveals that an outer membrane protein from the predator Bdellovibrio bacteriovorus forms a pentameric assembly that traps a lipid monolayer within. This allows...

www.nature.com

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Henrik Strahl @henrikstrahl.bsky.social · Sep 9

#microsky

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Sep 9

Measuring membrane fluidity in live mycobacteria reveals subcellular lateral variation and pole-selective responses to mycomembrane perturbation https://www.biorxiv.org/content/10.1101/2025.09.08.674961v1

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Erdinc Sezgin @sciezgin.bsky.social · Sep 8

Previous preprint is now published in RSC Chemical Biology.
If you are interested in plasma membrane labeling, see the paper! 👇
pubs.rsc.org/en/content/a...

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Henrik Strahl @henrikstrahl.bsky.social · Aug 22

#MicroSky

Henrik Strahl @henrikstrahl.bsky.social · Aug 22

This manuscript originated from a nice collaboration with Tjeerd van Rij from DSM-Firmenich and Colin Harwood.

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Henrik Strahl @henrikstrahl.bsky.social · Aug 22

A new methods paper from us, this time with a focus on reliable monitoring membrane potential and cell lysis at different growth stages and cell densities. Also, note the surprisingly high level of background lysis in seemingly healthy B. subtilis cultures.
www.biorxiv.org/content/10.1...

Monitoring single cell bioenergetic status and cell lysis in dense and differentiating Bacillus subtilis cultures

Bacillus subtilis is a major model organism for studying population heterogeneity in clonal bacterial cultures due to its high genetic tractability and ability to differentiate into subpopulations wit...

www.biorxiv.org

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Henrik Strahl @henrikstrahl.bsky.social · Aug 21

I thought everything that reduces the fitness of the bug?

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Henrik Strahl @henrikstrahl.bsky.social · Aug 20

'What is a virulence factor and how detect it' as volume 2?

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Henrik Strahl @henrikstrahl.bsky.social · Aug 20

Congratulations for the upgrade & get well soon!

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Ellinor Alseth @ellinoralseth.bsky.social · Aug 8

Feels surreal to say but: I'm hiring! If you are or know anyone interested in looking at the evolution of phage resistance using A. baumannii and natural transformation, then this might be for you
www.jobbnorge.no/en/available...

Research position in Microbial Pharmacology and Population Biology (282139) | UiT The Arctic University of Norway

Job title: Research position in Microbial Pharmacology and Population Biology (282139), Employer: UiT The Arctic University of Norway, Deadline: Wednesday, August 27, 2025

www.jobbnorge.no

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Reposted by Henrik Strahl

Michael Deghelt @michaeldeghelt.bsky.social · Jul 29

#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.

Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.

📄 www.nature.com/articles/s41...

Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria - Nature Microbiology

Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.

www.nature.com

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Paul Hoskisson 🧫 🦠🐸 @paulhoskisson.bsky.social · Jul 20

Superbugs could kill millions more and cost $2tn a year by 2050, models show www.theguardian.com/society/2025...

Superbugs could kill millions more and cost $2tn a year by 2050, models show

Exclusive: Research on burden of antibiotic resistance for 122 countries predicts dire economic and health outcomes

www.theguardian.com

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Susan Schlimpert @s-lab.bsky.social · Jul 10

New Independent Fellowship position in Microbiology to launch your lab in our department @johninnescentre.bsky.social (UK). We are conducting a broad search in the area of plant-associated microbial interactions. Message me if you have any questions.

Apply here: www.jic.ac.uk/vacancies/in...

Independent Fellowship in Plant-Associated Microbial Interactions | John Innes Centre

An exciting opportunity for an Independent Fellowship in Plant-Associated Microbial Interactions has arisen at the John Innes Centre. To read the full job description for this role…

www.jic.ac.uk

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Dr Katherine Duncan @kateduncan.bsky.social · Jul 7

Fascinating seminar by Prof @gebhardlab.bsky.social on ‘Building bacterial bridges – How an ancient bacterial trait can help us build the infrastructure of the future’ and visit at @cbcb-newcastle.bsky.social (hosted by @henrikstrahl.bsky.social) #bacillus #spores

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Henrik Strahl @henrikstrahl.bsky.social · Jul 4

Yep, its a really nice paper!

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Jan-Willem Veening @veeninglab.com · Jun 10

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM

wwwfbm.unil.ch

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Tracy Palmer @proftracypalmer.bsky.social · Jun 1

Check out our latest preprint! We show that the same antibacterial toxin requires different immunity proteins depending whether it’s intra or extracellular

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Jun 1

Distinct immunity protein families mediate compartment-specificneutralisation of a bacterial toxin https://www.biorxiv.org/content/10.1101/2025.05.31.657152v1

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