Bacterial immune systems have evolved in response to diverse molecular "parasites", yet their ecological roles remain poorly understood. This Essay explores how interactions between mobile genetic…

Decades of research into the noncoding transcriptome have unveiled a complex, multilayered web of molecular interactions that govern gene expression, protein synthesis, and cellular function, challeng...

Nucleus-forming jumbo bacteriophages display a surprisingly intricate replication cycle inside of bacterial host cells, challenging the long-standing paradigm of prokaryotic simplicity. The phage nucl...

PhD Project - MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Li...

Inducible gene expression is pivotal for dissecting bacterial physiology and virulence mechanisms. Across the Burkholderia genera, a limited range of inducible systems currently exist that show minima...

Screening of 1,076 compounds reveals 168 chemical pollutants with inhibitory effects on gut bacteria and genetic screens indicate commonality between pollutant and antibiotic resistance.

Abstract. Transformation occurs when bacteria import exogenous DNA via the competence machinery and integrate it into their genome through homologous recom

Bacteriophages have genomes that span a wide size range, are densely packed with coding sequences, and frequently encode genes of unknown function. Classical forward genetics has defined essential gen...

Phosphate (Pi) is one of the most important nutrients for plant growth and productivity, as it is an essential building block for a wide range of biomolecules. However, Pi is often poorly available in soils because of its low mobility and tendency to bind strongly to soil particles (Wang et al. 2025). This limitation poses a particular challenge for legumes, where symbiotic nitrogen fixation in root nodules demands high energy and phosphorus inputs. Under Pi limitation, nodules number is tightly regulated through the long-distance signaling pathway called autoregulation of nodulation (AON) to avoid an energetic imbalance (Isidra-Arellano and Valdes-López 2024). Although phosphate starvation responses (PSR) are well-characterized, the precise mechanisms by which Pi status is directly integrated into the genetic control of rhizobial nodulation have remained unclear.

Microbiology; Virology