Ira 'Bluebeard Homer' Goldman
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kdbyproxy.bsky.social
Ira 'Bluebeard Homer' Goldman
@kdbyproxy.bsky.social
6.1K followers 150 following 4.7K posts
I used to write laws… then I invented Knee Defender. ex-HPSCI, ex-Senate tech, taxes, trade/FP, ethics, antitrust… crime & even reputed parliamentarian
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kdbyproxy.bsky.social
David Letterman. Oprah and Uma.
Olivia Nuzzi. Donald Trump.
On the left: At the Oscars 1995. A screengrab of David Letterman as host, on stage, gesturing towards the unseen audience (and the camera). Below him, left is a screengrab of Oprah with big laughing smile, right is a screengrab of Uma Thurman with a big laughing smile. Below the Letterman image, and above the side-by-side Oprah and Uma images, there's text of what Letterman said that night. [but wait] Now, to the right of all that, two photos: Olivia Nuzzi in a leopard-skin-like skin-tight dress, from the high-waist up, against a sky-blue background. Somewhat below her and to the right is a photo of Donald Trump, seen from the high-waist up, looking sternly down at the photographer as Trump sits at the defendant's table at his New York City trial. Yellow tie, white shirt, standard blue suit. His right hand clenched, resting on the table, his left hand resting on it. The text on the left is Letterman saying, "Oprah... Uma." Then "Uma... Oprah." On the right, text below Nuzzi's photo says "Nuzzi." And that's it.
November 27, 2025 at 5:34 AM
kdbyproxy.bsky.social
Link to the full study: "Adolescent Opioid Abuse: Role of Glial and Neuroimmune Mechanisms". scholarworks.indianapolis.iu.edu/server/api/c... And I'm posting the screen grab of the Conclusion section again, this time with the Alt text.

Study abridged version: www.sciencedirect.com/science/chap...
Adolescent Opioid Abuse: Role of Glial and Neuroimmune Mechanisms S. Rahman - 1, Z.I. Rahman - 2, P.J. Ronan - 3, K. Lutfy - 4, R.L. Bell - 5 1Department of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA; 2 – University of Minnesota Medical School, Minneapolis, MN 55455, USA 3 – Department of Psychiatry and Basic Biomedical Sciences, Sanford USD School of Medicine, University of South Dakota; Sioux Falls VA Healthcare System Sioux Falls, SD 57105, USA; 4 – Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA; 5 – Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA [snip] 7. CONCLUSIONS In this review, we have explored evidence that opioid abuse during adolescence can modify brain functions and produce drug–specific neurobehavioral consequences. The preclinical and clinical data discussed above indicate that exposure to opioids during adolescence can cause long-lasting neurobiological, cognitive, affective, and behavioral dysfunctions. The net result is an impaired brain function that lasts into adulthood. Moreover, the development of multiple brain regions is particularly sensitive to adolescent opioid exposure. In addition, we have reviewed that neuroimmune signaling pathways mediate opioid-induced glial activation and associated cellular and molecular mechanisms. Furthermore, recent studies have revealed an important role for neuroimmune mechanisms, including glial activation, in many actions of opioids in the brain. These actions include neural damage, cognitive dysfunction, and alterations to reward neurocircuitry. Therefore, targeting neuroimmune signaling, including glial activation is a viable therapeutic strategy for future prevention and treatment of OUDs.
November 27, 2025 at 4:37 AM
kdbyproxy.bsky.social
Another study: "Adolescent Opioid Abuse: Role of Glial and Neuroimmune Mechanisms"

"[O]pioid abuse during adolescence […] can cause long-lasting neurobiological, cognitive, affective, and behavioral dysfunctions. The net result is an impaired brain function that lasts into adulthood."

That said…
November 27, 2025 at 4:26 AM
kdbyproxy.bsky.social
If you think studies w/ mice & rats cld be applicable to humans, then RFKjr's adolescent use of heroin may be a part of the problem. Eg, "Adolescent morphine exposure induced long-term cognitive impairment and prefrontal neurostructural abnormality in adulthood in male mice"

doi.org/10.1016/j.he...
Research article Adolescent morphine exposure induced long-term cognitive impairment and prefrontal neurostructural abnormality in adulthood in male mice Ye Lu, Yijie Guo, Lulu Sun, Tong Liu, Ziqing Dong, Min Jia, Lixia Zhuo, Fangyuan Yin, Yongsheng Zhu, Xiancang Ma, Yunpeng Wang, Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, 710061, China Shaanxi Key Laboratory of Biological Psychiatry, Xi’an, Shaanxi, 710061, China c College of Forensic Science, School of Medicine […] China School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, 211166, China, Lead Contact, China A B S T R A C T Opioids abuse in adolescence is becoming a pressing public health issue. While evidence suggests that exposure to opioids during adolescence leads to lasting alterations in brain development, the long-term cognitive implications in adulthood remain uncertain. We developed a male mouse model of adolescent morphine exposure and used the 5-choice serial reaction time task (5-CSRTT), along with the open field, novel object recognition, Y maze and Barnes maze tests, to assess changes in cognitive behavior. We found that exposure to morphine during adolescence led to deficits in multidimensional cognitive functions in mice, including attention, information processing speed, and behavior inhibition. Notable, these impairments persisted into adulthood. Furthermore, the morphine-exposed mice exhibited decreased learning efficiency and spatial memory. Adolescent morphine exposure also induced significant and persistent morphological changes and synaptic abnormalities in medial prefrontal cortex (mPFC) neurons, which may be responsible for cognitive impairments in adulthood. Together, our study suggests that opioid exposure during adolescence profoundly affects cognitive development and emphasizes that opioid-induced disruption of neurons in adolescence may link mPFC-associated cognitive impairments in adulthood.
November 27, 2025 at 1:49 AM
kdbyproxy.bsky.social
Oh, I thought it was a desktop version of this.
November 26, 2025 at 10:20 PM
kdbyproxy.bsky.social
DATA: When something bad happens, MAGA blames it on whoever they last rage-tweeted about.
November 26, 2025 at 10:00 PM
kdbyproxy.bsky.social
Apart from whether or not this is the right response, we now know from his response time today that, while Trump may not really care about our troops, he cares more about the troops than he does about members of Congress.
November 26, 2025 at 9:55 PM
kdbyproxy.bsky.social
DAILY BEAST: "Trump is reportedly locked in a bizarre standoff with the architect he personally tapped to design a new White House ballroom – b/c the president wants it even bigger than the White House itself."

In the last image his architect released, its footprint looked bigger already.

1/
Daily Beast HEADLINE: Trump, 79, Feuds With His White House Ballroom Architect Over Bonkers Demand ARCH NEMESIS The president and architect James McCrery II have butted heads, insiders claim.
November 26, 2025 at 7:54 PM
kdbyproxy.bsky.social
HEADLINE: Trump says China's Xi 'more or less agreed' [ fill in the blank ]

I'll take the under.

www.reuters.com/world/china/...
HEADLINE: Trump says China's Xi 'more or less agreed' to accelerate purchases of US goods By Reuters November 25, 202510:52 PM EST
November 26, 2025 at 7:24 PM
kdbyproxy.bsky.social
At Boston U's College of Communications (aka, SPC), some students made a short film about a couple of guys deciding to sell shit in a can and then marketing it into a huge success... ~55 years ago.
November 26, 2025 at 7:13 PM
kdbyproxy.bsky.social
"relayed"? Because the court couldn't think of a word even more innocuous?

😁
Screenshot of the bottom of page 17, top of page 18 of the court's opinion, with the word "relayed" highlighted. [case linkhttps://storage.courtlistener.com/recap/gov.uscourts.ca11.80225/gov.uscourts.ca11.80225.251.1.pdf] None of these proceedings are, or even resemble, a racketeering action. At best, they are actions involving some of the conduct that Trump incorporates into his racketeering claim. But none of these actions are even prosecutions of a racketeering predicate act. The Commission’s action objected to the Democratic National Committee’s and Clinton campaign’s “mischaracteriz[ation] . . . of certain disbursements,” and at most establishes that the campaign [Filing header in purple] USCA11 Case: 22-13410 Document: 251-1 Date Filed: 11/26/2025 Page: 18 of 36 [Now back to the opinion] 18 Opinion of the Court 22-13410 relayed funds through Perkins Coie to opposition research. And the Sussmann, Danchenko, and Clinesmith prosecutions for making false statements to federal officials are relevant only to discrete parts of Trump’s claims. These facts do not amount to a racketeering enterprise or a racketeering conspiracy.
November 26, 2025 at 5:04 PM
kdbyproxy.bsky.social
And a package cannot be "delayed in transit" when it has yet to start its transit.
Two images. On the left, screenshot of a post of the Norman Rockwell painting of a man standing to speak at a town hall meeting, with the comment, "A package hasn't 'shipped' if you've only 'created the label'" To its right, a screenshot of tracking status of a package ordered from Amazon - dates are in chron order, times are reverse chron Shipped with Amazon Tracking ID: ************** Monday, November 24 8:00 PM - Package delayed in transit 7:00 PM - Package delayed in transit 4:19 AM - Delivery appointment scheduled US Then Tuesday, November 25 - Package left the shipper facility
November 26, 2025 at 1:38 AM
kdbyproxy.bsky.social
And in school buses, why require companies to install improved child restraint systems? I mean, when you think about it, it'd be less costly, and really just as good, if we instead had the companies install labels that say those improved systems aren't in this bus.*

(* – or I'm reading it wrong)
November 26, 2025 at 1:10 AM
kdbyproxy.bsky.social
From the link, it appears that that memo was posted in 2022 and was one of multiple attachments to something. To what? Donno.
Screenshot of the URL for that memo: https://www.justice.gov/d9/pages/attachments/2022/10/17/la_19810116_the_power_of_congress_to_abrogate_its_members_rights_under_the_speech_or_debate_clause.pdf
November 25, 2025 at 11:22 PM
kdbyproxy.bsky.social
FUN FIND: On Carter's way out the door in 1981, AAG Phil Heymann rec'd an OLC memo: "We believe that Congress may not 'waive' or abrogate its members' rights under the Speech or Debate Clause. [… T]he clause protects Congress chiefly by protecting the speech and debate of every member."

Link in ALT
Date stamped: 16 Jan 1981 MEMORANDUM FOR PHILIP B. HEYMANN Assistant 'Attorney General Criminal Division Re: The Power of Congress to Abrogate its Members' Rights under the Speech or Debate Clause In your memorandum of September 18, 1979, you asked our opinion whether Congress can "waive" its members' rights under the Speech or Debate Clause of the Constitution. The Solicitor General has taken the position, in the Supreme Court, that Congress has the power to abrogate its members' Speech or Debate Clause protection. See Brief for the United States at 18-21, 76-88, United States v. Helstoski, 442 U.S. 477 (1979); Brief for the United States. at 10-32, United States v. Brewster, 408 U.S. 501 (1972). We disagree. We believe that Congress may not "waive" or abrogate its members' rights under the Speech or Debate Clause. [snip] But in our view the clause protects Congress chiefly by protecting the speech and debate of every member -- even if a majority of his colleagues wish to deny him that protection. https://www.justice.gov/d9/pages/attachments/2022/10/17/la_19810116_the_power_of_congress_to_abrogate_its_members_rights_under_the_speech_or_debate_clause.pdf
November 25, 2025 at 11:12 PM
kdbyproxy.bsky.social
TIL: I can set my home thermostat to lie.

"Can we get some heat in here?!"
"Put on a sweater."
"But–?"
"What does the thermostat say?"
"70."
"70?! That is warm enough."
This feature allows the installer to change the calibration of the room temperature display. For example: If the thermostat reads 70° and you would like it to read 72° then select +2. You can adjust the room temperature display to ready -4° F to +4° F above or below the factory calibrated reading. Follow the steps below to adjust the temperature reading
November 25, 2025 at 9:36 PM
kdbyproxy.bsky.social
File under "Things that government can do when your country has a Constitution but it's unwritten"
November 25, 2025 at 7:19 PM
kdbyproxy.bsky.social
… the guy punched him." (What some people said they saw while others said they didn't in videos of this "incident" ↙️ by the Lincoln Memorial in 2019 is a strong example.)

But even by the standard of "It's not a lie if he believed it," insisting that ↘️ is a "cement barrier" is a lie.

3/3
Photo of a high-school-age student and an elderly Native American man facing each other directly, maybe just a few feet apart. Behind the student are a bunch of other students. And behind those students we can see the top of a marble building, which (while maybe not identifiable here) is the Lincoln Memorial. This is from what became a high-profile incident between the student and the Native American man by the Lincoln Memorial in 2019. Same image as attached to my first post - testimony and the image of men in military green wrestling on the ground with a man wearing blue jeans.
November 25, 2025 at 7:06 PM
kdbyproxy.bsky.social
When I first read that testimony clip, I thought the lawyer maybe used "guardrail" as a generic term but Bovino didn't want to accept generic and replied with "a cement barrier". But then I saw this image. 🤯 A literal guardrail. And afaik they're metal, not "cement".*

(* – ie, concrete; IYKYK)
1/
A portion of OP's clip of a court transcript: Q: Now the area in question is behind a guardrail, right? A: There was a cement barrier. There's not a -- a guardrail. Below that is an image of 2 men in military green wrestling on the ground with a man wearing blue jeans. Also in the image, a few feet away from them, is a metal guardrail, the type typically used along roadways.
November 25, 2025 at 7:06 PM
kdbyproxy.bsky.social
And as for Venezuela...

bsky.app/profile/bill...
November 24, 2025 at 9:45 PM
kdbyproxy.bsky.social
PSA: Military retirement appears to be exempt from congressional financial disclosure reporting (as is the value of a senator's primary residence).

Re: Senator Mark Kelly (D-AZ)
Senate Ethics Committee, financial disclosure instructions for Calendar Year 2023 (for filing in 2024) FROM: Senate Ethics Committee, financial disclosure instructions for Calendar Year 2023 (for filing in 2024) You are not required to report earned income for your dependent children. Include all earned income and non-investment income, including, but not limited to, fees, commissions, salaries, income from personal services, retirement income, pension payments, royalty payments, and gambling or lottery winnings. You are not required to report any income from the U.S. Government, including, but not limited to, your Senate salary, military pay from military reserve duty, social security income, and federal retirement income.
November 24, 2025 at 9:17 PM
kdbyproxy.bsky.social
"The Republican from Surprise," indeed.

😁
November 24, 2025 at 7:08 AM
kdbyproxy.bsky.social
1) Who knew Keith Kellogg was still at his post? 🤷🏻‍♂️

2) "But his role shrunk as Witkoff, a real estate developer TURNED diplomat, emerged as the president’s chief interlocutor with Putin and his advisers."
> But we would have accepted "real estate developer turned Trump/Putin real estate developer."
ABC NEWS Headline: Trump's Ukraine envoy Keith Kellogg expected to leave his post as new peace plan emerges Subhed: President Donald Trump’s special envoy to Ukraine, Keith Kellogg, has informed the White House he’ll leave his post in January By AAMER MADHANI Associated Press November 20, 2025, 6:54 PM
November 24, 2025 at 4:19 AM
kdbyproxy.bsky.social
A TAKE: Zelensky goes to the White House, and in the Oval Office he rolls out a big map that shows all the territory of Ukraine that Russia now occupies, then he makes this offer: Trump gets 6% of whatever he recovers.
File photo of Trump and Zelensky, seated in chairs with gold-tone metal frames and red upholstered backs, seats, and armrests, facing each other, both leaning in towards each other, in a large space with a marble inlay floor, in the Vatican, in a one-on-one meeting.
November 23, 2025 at 11:48 PM
kdbyproxy.bsky.social
I've deleted my post re the SEAR/security rating for the Las Vegas F1 races this weekend being changed because, while I did note the source was Google AI, upon booth review I am told that it's wrong.
November 23, 2025 at 10:54 PM