Darwin Del Castillo, MD MPH
justpvalues.bsky.social
Darwin Del Castillo, MD MPH
@justpvalues.bsky.social
MPH @uwsph.bsky.social | MD 🇵🇪 | First-gen physician and geek | #GlobalHealth #EpiTwitter #NCDs | Proud tutor of two cats | Opinions are personal.
Reposted by Darwin Del Castillo, MD MPH
Scalable Medication Extraction and Discontinuation Identification from Electronic Health Records Using Large Language Models - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Scalable Medication Extraction and Discontinuation Identification from Electronic Health Records Using Large Language Models
Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to eval...
www.jclinepi.com
November 17, 2025 at 7:21 PM
Reposted by Darwin Del Castillo, MD MPH
People with early-onset obesity (diagnosed at age < 25 yrs) may present with more cardiometabolic abnormalities & obesity-related complications..

Early-Onset Obesity and Tirzepatide Treatment: A Post Hoc Analysis of the SURMOUNT Clinical Trials.

onlinelibrary.wiley.com/doi/10.1002/...
August 22, 2025 at 7:48 AM
Reposted by Darwin Del Castillo, MD MPH
Systematic reviews are the ultimate symbol of the unthinking box ticking evidence synthesis machine.

I gather we've passed the point where there are now more systematic reviews of RCTs than original RCTs.

What a wonderful achievement for humankind.
July 24, 2025 at 7:04 AM
Reposted by Darwin Del Castillo, MD MPH
Self-reported race is NOT a proxy for genetic ancestry. Don't ever use it that way, even "approximately". www.cell.com/ajhg/fulltex...
Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research
Analysis of 230,016 genomes in the All of Us Research Program revealed substantial variation in continental and subcontinental ancestry within self-reported race and ethnicity across the US. Subcontin...
www.cell.com
June 6, 2025 at 5:28 AM
Reposted by Darwin Del Castillo, MD MPH
To me, a Nazi salute means, "I want to murder your family." There can be no irony about it: It puts deep anger and hatred in my heart to see it done and I will never forgive anyone who justifies or minimizes it.
February 23, 2025 at 6:14 PM
Reposted by Darwin Del Castillo, MD MPH
BREAKING: NIH admits funding freeze is illegal, will resume issuing grants @juddlegum.bsky.social @popular.info open.substack.com/pub/populari...
BREAKING: NIH admits funding freeze is illegal, will resume issuing grants
An internal memo issued February 12 was obtained by Popular Information.
open.substack.com
February 12, 2025 at 7:38 PM
Reposted by Darwin Del Castillo, MD MPH
I sincerely don’t know why people aren’t physically stopping those dorks. Move shit. Lock doors. Lose the keys. Everyone switch seats. Turn off all the lights. Switch the signs on the elevator lobby. Make the settings all silly. Use a different language. Wear costumes. Fill rooms with balloons
February 5, 2025 at 11:07 PM
Reposted by Darwin Del Castillo, MD MPH
Medical journal editors must resist CDC order and anti-gender ideology

www.bmj.com/content/388/...
February 4, 2025 at 5:52 PM
Reposted by Darwin Del Castillo, MD MPH
For years now, groups like Oxfam have warned us about a small number of men accumulating more wealth than half the world’s population

These men today are buying elections, backing fascists, and preparing to become trillionaires

By not taxing them, we invited the unfolding disaster
February 4, 2025 at 6:07 PM
Reposted by Darwin Del Castillo, MD MPH
“A group of researchers and students at the Harvard T.H. Chan School of Public Health is gathered today for a data preservation marathon, scraping and downloading data related to health equity from U.S. government agency websites before they disappear.”
Researchers rush to preserve federal health databases before they disappear from government websites
Journalists have long relied on federal health data for their reporting. We include several tips that they can use to help researchers preserve the data.
journalistsresource.org
February 1, 2025 at 3:04 AM
Reposted by Darwin Del Castillo, MD MPH
🚨 The indefinite pause on NIH study sections & CDC public communication updates is devastating for science, public health, and our future. These decisions will have long-term consequences for research, disease prevention, and lives if they are prolonged.
A 🧵
January 23, 2025 at 7:32 PM
Reposted by Darwin Del Castillo, MD MPH
This is such a great journal cover (and journal)! https://journal.trialanderror.org/. Cover by Lieve Visser.

#journaloftrialanderror #academicpublishing
January 21, 2025 at 9:14 AM
Reposted by Darwin Del Castillo, MD MPH
The way “global health” people have stated the value of WHO to the US (and to the world) and what’s at stake in US withdrawal from WHO has been very revealing of the strong neocolonial tendencies/undercurrents that shape how people do “global health” and how the field works.
January 21, 2025 at 7:56 AM
Reposted by Darwin Del Castillo, MD MPH
A Standing Desk is not healthier than sitting. (Internat. J. Epidemiology) https://buff.ly/3Z1e6ou
November 23, 2024 at 11:02 PM
Reposted by Darwin Del Castillo, MD MPH
ICYMI: The BMJ published a long series of Statistics Notes. They are all short essays on specific topics in medical statistics written for a broad audience of medical researchers. You could do worse than to organize a journal club based on these papers. www-users.york.ac.uk/~mb55/pubs/p...
Statistics Notes in the British Medical Journal
www-users.york.ac.uk
July 19, 2024 at 5:16 AM
Reposted by Darwin Del Castillo, MD MPH
🚀We'll launch "Global Health 2050," the 3rd report of our Lancet Commission on Investing in Health, on Oct 15 at the World Health Summit in Berlin!

The 2 launch events will stream online:

🕑2-3.30pm Berlin time www.youtube.com/watch?v=KS95...

🕔4-5.30pm Berlin time www.youtube.com/watch?v=oHl-...
September 18, 2024 at 7:15 PM