Jeremy Hogeveen
@jeremyhogeveen.bsky.social
Brain imager (and occasional tinkerer) @ The University of New Mexico. https://www.hogeveen-lab.com/
Meeting of the minds at my mother-in-law's farm this morning.
November 24, 2025 at 4:59 PM
Meeting of the minds at my mother-in-law's farm this morning.
Reposted by Jeremy Hogeveen
Another nail in the coffin for PCA?
- doesn’t linearize, distorting similarity metrics
- is biased by temporal jitter across epochs
- may miss important dimensions for transient amplification
If you think there is a state space, use a state space model!
- doesn’t linearize, distorting similarity metrics
- is biased by temporal jitter across epochs
- may miss important dimensions for transient amplification
If you think there is a state space, use a state space model!
“Our findings challenge the conventional focus on low-dimensional coding subspaces as a sufficient framework for understanding neural computations, demonstrating that dimensions previously considered task-irrelevant and accounting for little variance can have a critical role in driving behavior.”
Neural dynamics outside task-coding dimensions drive decision trajectories through transient amplification
Most behaviors involve neural dynamics in high-dimensional activity spaces. A common approach is to extract dimensions that capture task-related variability, such as those separating stimuli or choice...
www.biorxiv.org
November 23, 2025 at 3:16 PM
Another nail in the coffin for PCA?
- doesn’t linearize, distorting similarity metrics
- is biased by temporal jitter across epochs
- may miss important dimensions for transient amplification
If you think there is a state space, use a state space model!
- doesn’t linearize, distorting similarity metrics
- is biased by temporal jitter across epochs
- may miss important dimensions for transient amplification
If you think there is a state space, use a state space model!
Reposted by Jeremy Hogeveen
“Our findings challenge the conventional focus on low-dimensional coding subspaces as a sufficient framework for understanding neural computations, demonstrating that dimensions previously considered task-irrelevant and accounting for little variance can have a critical role in driving behavior.”
Neural dynamics outside task-coding dimensions drive decision trajectories through transient amplification
Most behaviors involve neural dynamics in high-dimensional activity spaces. A common approach is to extract dimensions that capture task-related variability, such as those separating stimuli or choice...
www.biorxiv.org
November 23, 2025 at 1:38 PM
“Our findings challenge the conventional focus on low-dimensional coding subspaces as a sufficient framework for understanding neural computations, demonstrating that dimensions previously considered task-irrelevant and accounting for little variance can have a critical role in driving behavior.”
Reposted by Jeremy Hogeveen
we have PrEP because of these monkey studies. animal welfare in medical research is extremely strictly limited and regulated to ensure ethical use. there is no replacement for these animal models in biomedical research.
EXCLUSIVE: CDC to end all monkey studies. Decision handed down by recent college grad and former DOGE employee who is now deputy chief of staff at the agency. Animals were being used in studies of HIV prevention. Some may be euthanized. My latest for @science.org
Exclusive: CDC to end all monkey research
Studies related to HIV and other infectious diseases will be phased out, sources say; fate of the agency's animals remains unclear
www.science.org
November 21, 2025 at 2:48 PM
we have PrEP because of these monkey studies. animal welfare in medical research is extremely strictly limited and regulated to ensure ethical use. there is no replacement for these animal models in biomedical research.
Reposted by Jeremy Hogeveen
"Nice" NIH study sections screw their applicants because of the way NIH calculates percentile. drugmonkey.wordpress.com/2025/11/20/n...
“Nice” NIH study sections screw their applicants because of the way NIH calculates percentile.
I often write blog comments about NIH grant review matters that exist in an uncomfortable tension between what NIH wants us to do on study section and what I see as our professional obligation to t…
drugmonkey.wordpress.com
November 21, 2025 at 1:50 AM
"Nice" NIH study sections screw their applicants because of the way NIH calculates percentile. drugmonkey.wordpress.com/2025/11/20/n...
Reposted by Jeremy Hogeveen
If your ultimate inference target is the group level, then what matters is the joint contribution of trial number per condition and participant sample size, not either one in isolation. We explored this point in detail here:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Hyperbolic trade-off: The importance of balancing trial and subject sample sizes in neuroimaging
Here we investigate the crucial role of trials in task-based neuroimaging from the perspectives of statistical efficiency and condition-level generali…
www.sciencedirect.com
November 21, 2025 at 3:37 AM
If your ultimate inference target is the group level, then what matters is the joint contribution of trial number per condition and participant sample size, not either one in isolation. We explored this point in detail here:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Very excited to hear about this! We find Bayesian multi-level modeling at the ROI level super helpful (e.g. www.cell.com/neuron/fullt... ), will be nice to not have to artificially carve the data into parcels a priori!
November 20, 2025 at 8:35 PM
Very excited to hear about this! We find Bayesian multi-level modeling at the ROI level super helpful (e.g. www.cell.com/neuron/fullt... ), will be nice to not have to artificially carve the data into parcels a priori!
Reposted by Jeremy Hogeveen
And the next step? Full voxel-level modeling.
Recent numerical advances cracked the scalability barrier. Voxel-level hierarchical modeling is now feasible, revealing just how punishing traditional multiple-comparison adjustments really are.
arxiv.org/abs/2511.12825
Recent numerical advances cracked the scalability barrier. Voxel-level hierarchical modeling is now feasible, revealing just how punishing traditional multiple-comparison adjustments really are.
arxiv.org/abs/2511.12825
SIMBA: Scalable Image Modeling using a Bayesian Approach, A Consistent Framework for Including Spatial Dependencies in fMRI Studies
Bayesian spatial modeling provides a flexible framework for whole-brain fMRI analysis by explicitly incorporating spatial dependencies, overcoming the limitations of traditional massive univariate app...
arxiv.org
November 18, 2025 at 10:13 PM
And the next step? Full voxel-level modeling.
Recent numerical advances cracked the scalability barrier. Voxel-level hierarchical modeling is now feasible, revealing just how punishing traditional multiple-comparison adjustments really are.
arxiv.org/abs/2511.12825
Recent numerical advances cracked the scalability barrier. Voxel-level hierarchical modeling is now feasible, revealing just how punishing traditional multiple-comparison adjustments really are.
arxiv.org/abs/2511.12825
Unable to be there, but thrilled that lab grad student Cidney Robertson-Benta is presenting today at the Women+ in Cognitive Control Psychonomics satellite in Denver: sites.google.com/view/wiccmee...
Event
Scope and Goal
Founded in 2021, Women+ in (Cognitive) Control aims to promote and support women and gender diverse researchers in cognitive control. Coinciding with the 2025 Annual Meeting of the Psyc...
sites.google.com
November 20, 2025 at 4:15 PM
Unable to be there, but thrilled that lab grad student Cidney Robertson-Benta is presenting today at the Women+ in Cognitive Control Psychonomics satellite in Denver: sites.google.com/view/wiccmee...
late show musical guest Youtube is a goldmine
Radiohead Perform "Fake Plastic Trees" Live on June 12, 1995 | Late Night with Conan O’Brien
YouTube video by Conan O'Brien
www.youtube.com
November 20, 2025 at 3:13 PM
late show musical guest Youtube is a goldmine
Ditto(ish) for our section. Rescheduled from early November to early January!
Just to add a data point: A study section I'm on that was originally scheduled for late October is now being rescheduled for mid-January. #nihgrants
November 19, 2025 at 5:17 PM
Ditto(ish) for our section. Rescheduled from early November to early January!
Reposted by Jeremy Hogeveen
WILLIAM ANDREW MICHAEL JUNIOR NYLANDER ALTELIUS!!!!
@OREO | #LeafsForever
@OREO | #LeafsForever
November 19, 2025 at 3:09 AM
WILLIAM ANDREW MICHAEL JUNIOR NYLANDER ALTELIUS!!!!
@OREO | #LeafsForever
@OREO | #LeafsForever
Reposted by Jeremy Hogeveen
My paper is out!
Computational modeling of error patterns during reward-based learning show evidence that habit learning (value free!) supplements working memory in 7 human data sets.
rdcu.be/eQjLN
Computational modeling of error patterns during reward-based learning show evidence that habit learning (value free!) supplements working memory in 7 human data sets.
rdcu.be/eQjLN
A habit and working memory model as an alternative account of human reward-based learning
Nature Human Behaviour - In this study, Collins proposes an alternative dual-process (working memory and habit) model of reinforcement learning in humans.
rdcu.be
November 17, 2025 at 5:18 PM
My paper is out!
Computational modeling of error patterns during reward-based learning show evidence that habit learning (value free!) supplements working memory in 7 human data sets.
rdcu.be/eQjLN
Computational modeling of error patterns during reward-based learning show evidence that habit learning (value free!) supplements working memory in 7 human data sets.
rdcu.be/eQjLN
Reposted by Jeremy Hogeveen
New preprint with @hollysully.bsky.social & @kevinmking.bsky.social:
Alcohol intoxication and negative mood similarly affect reward learning but not punishment learning in the Iowa Gambling Task
doi.org/10.31219/osf...
Alcohol intoxication and negative mood similarly affect reward learning but not punishment learning in the Iowa Gambling Task
doi.org/10.31219/osf...
May 16, 2025 at 2:27 PM
New preprint with @hollysully.bsky.social & @kevinmking.bsky.social:
Alcohol intoxication and negative mood similarly affect reward learning but not punishment learning in the Iowa Gambling Task
doi.org/10.31219/osf...
Alcohol intoxication and negative mood similarly affect reward learning but not punishment learning in the Iowa Gambling Task
doi.org/10.31219/osf...
Hearing colleagues say “let’s get AI to draft some bullet points instead of writing papers” suggests science may go full Wall-E faster than I’d realized…
November 16, 2025 at 5:26 AM
Hearing colleagues say “let’s get AI to draft some bullet points instead of writing papers” suggests science may go full Wall-E faster than I’d realized…
Interested in spatiotemporal decoding of choice and feedback in the human brain?
My lab’s postdoc Rohit Yadav will present these beautiful MEG results from our novelty bandit at #SFN2025 Sunday 11/16, PSTR094.23 / LL8 (top row: explore vs exploit; bottom: reward vs nonreward)
My lab’s postdoc Rohit Yadav will present these beautiful MEG results from our novelty bandit at #SFN2025 Sunday 11/16, PSTR094.23 / LL8 (top row: explore vs exploit; bottom: reward vs nonreward)
November 15, 2025 at 2:11 AM
Interested in spatiotemporal decoding of choice and feedback in the human brain?
My lab’s postdoc Rohit Yadav will present these beautiful MEG results from our novelty bandit at #SFN2025 Sunday 11/16, PSTR094.23 / LL8 (top row: explore vs exploit; bottom: reward vs nonreward)
My lab’s postdoc Rohit Yadav will present these beautiful MEG results from our novelty bandit at #SFN2025 Sunday 11/16, PSTR094.23 / LL8 (top row: explore vs exploit; bottom: reward vs nonreward)
Reposted by Jeremy Hogeveen
14 months after submission, our article “Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI" is now out in @natmethods.nature.com . You can read it here rdcu.be/ePJo6
It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N
It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N
Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI
Nature Methods - Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with...
rdcu.be
November 13, 2025 at 12:23 PM
14 months after submission, our article “Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI" is now out in @natmethods.nature.com . You can read it here rdcu.be/ePJo6
It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N
It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N
Reposted by Jeremy Hogeveen
After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:
Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications
The landmark ongoing HEALthy Brain and Cognitive Development (HBCD) study will longitudinally chart brain development in a large sample (projected n=7,200) of infants through age 10 years with multimo...
www.biorxiv.org
November 11, 2025 at 10:03 PM
After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:
Reposted by Jeremy Hogeveen
Truly heroic work by the stellar @cieslakmatt.bsky.social + the HBCD dMRI working group team. Refactored QSIPrep + QSIRecon is the result of nearly 3y of concerted development + testing. It will be a total workhorse for HBCD -- and almost any other dMRI scan. Check it out for your data!!!
After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:
Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications
The landmark ongoing HEALthy Brain and Cognitive Development (HBCD) study will longitudinally chart brain development in a large sample (projected n=7,200) of infants through age 10 years with multimo...
www.biorxiv.org
November 12, 2025 at 2:18 PM
Truly heroic work by the stellar @cieslakmatt.bsky.social + the HBCD dMRI working group team. Refactored QSIPrep + QSIRecon is the result of nearly 3y of concerted development + testing. It will be a total workhorse for HBCD -- and almost any other dMRI scan. Check it out for your data!!!
Reposted by Jeremy Hogeveen
Please share! Going to #SfN and looking for a postdoc in human neuroscience? We're hiring! If you have a background in Psychology, Neuroscience, Biomedical Engineering, or related areas, come talk to us about joining our lab at Georgia Tech (siplab.gatech.edu). #neuroscience #PsychSciSky
SIPLab
siplab.gatech.edu
November 11, 2025 at 9:28 PM
Please share! Going to #SfN and looking for a postdoc in human neuroscience? We're hiring! If you have a background in Psychology, Neuroscience, Biomedical Engineering, or related areas, come talk to us about joining our lab at Georgia Tech (siplab.gatech.edu). #neuroscience #PsychSciSky
Reposted by Jeremy Hogeveen
Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao.
#neuroskyence
bit.ly/47MXYLH
#neuroskyence
bit.ly/47MXYLH
Without monkeys, neuroscience has no future
Research in primate brains has been essential for the development of BCIs, ANNs. New funding and policy changes put future such advances at risk.
bit.ly
November 10, 2025 at 2:56 PM
Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put future such advances at risk, write Cory Miller, @movshon.bsky.social and Doris Tsao.
#neuroskyence
bit.ly/47MXYLH
#neuroskyence
bit.ly/47MXYLH
Reposted by Jeremy Hogeveen
Reposted by Jeremy Hogeveen
My reviewing style has changed over time. Rather than litigate every little thing, and pushing my own ideas, I focus only on 2 things:
(1) Are the claims interesting/important?
(2) Does the evidence support the claims?
Most of my reviews these days are short and focused.
(1) Are the claims interesting/important?
(2) Does the evidence support the claims?
Most of my reviews these days are short and focused.
November 8, 2025 at 11:22 AM
My reviewing style has changed over time. Rather than litigate every little thing, and pushing my own ideas, I focus only on 2 things:
(1) Are the claims interesting/important?
(2) Does the evidence support the claims?
Most of my reviews these days are short and focused.
(1) Are the claims interesting/important?
(2) Does the evidence support the claims?
Most of my reviews these days are short and focused.