Immunometabolism forum
@immunometforum.bsky.social
Forum for early career researchers to share and learn immunometabolism research
Reposted by Immunometabolism forum
Our paper on nurturing a #PositiveResearchCulture within your #research #team published by @wellcometrust.bsky.social gives useful tips for your lab. As well as making you a good team leader, nurturing culture pays off in building your science: 1/11
wellcomeopenresearch.org/articles/9-3...
wellcomeopenresearch.org/articles/9-3...
wellcomeopenresearch.org
January 14, 2025 at 9:55 AM
Our paper on nurturing a #PositiveResearchCulture within your #research #team published by @wellcometrust.bsky.social gives useful tips for your lab. As well as making you a good team leader, nurturing culture pays off in building your science: 1/11
wellcomeopenresearch.org/articles/9-3...
wellcomeopenresearch.org/articles/9-3...
Reposted by Immunometabolism forum
Check out our new commentary on this interesting study by @justinaguerrero.bsky.social and team on Glut1 overexpressing CAR T cells. Excited to see what comes next for these metabolically enhanced T cells!
@davidfinlaytcd.bsky.social
@davidfinlaytcd.bsky.social
La dolce vita: fueling chimeric antigen receptor (CAR) T... : Immunometabolism
y of patients relapse, which is concomitant with poor CAR T cell persistence. Similarly, the efficacy of CAR T cell therapy is limited in solid tumors, largely due to tumor antigen heterogeneity, immu...
journals.lww.com
January 13, 2025 at 1:33 PM
Check out our new commentary on this interesting study by @justinaguerrero.bsky.social and team on Glut1 overexpressing CAR T cells. Excited to see what comes next for these metabolically enhanced T cells!
@davidfinlaytcd.bsky.social
@davidfinlaytcd.bsky.social
Reposted by Immunometabolism forum
PKM2 has always been intriguing; complex roles in some cells, here involving adenosine in #macrophages, simple glycolytic enzyme in #NKcells (doi.org/10.7554/eLif...)
#immunometabolism #immunosky
Metabolic reprogramming of macrophages by PKM2 promotes IL-10 via adenosine www.cell.com/cell-reports...
#immunometabolism #immunosky
Metabolic reprogramming of macrophages by PKM2 promotes IL-10 via adenosine www.cell.com/cell-reports...
Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine
TEPP-46 activates PKM2 by inducing a tetramer formation, which leads to a metabolic
reprogramming in macrophages, resulting in an increase in ATP and IL-10 production.
Toller-Kawahisa et al. showed th...
www.cell.com
January 15, 2025 at 12:21 AM
PKM2 has always been intriguing; complex roles in some cells, here involving adenosine in #macrophages, simple glycolytic enzyme in #NKcells (doi.org/10.7554/eLif...)
#immunometabolism #immunosky
Metabolic reprogramming of macrophages by PKM2 promotes IL-10 via adenosine www.cell.com/cell-reports...
#immunometabolism #immunosky
Metabolic reprogramming of macrophages by PKM2 promotes IL-10 via adenosine www.cell.com/cell-reports...
Reposted by Immunometabolism forum
More nice research from Annie Curtis’ lab on the circadian rhythm and the
#immunometabolism of macrophages.
#immunosky #mitochondria #inflammasome
Time‐of‐day control of mitochondria regulates NLRP3 inflammasome activation in macrophages faseb.onlinelibrary.wiley.com/doi/10.1096/...
#immunometabolism of macrophages.
#immunosky #mitochondria #inflammasome
Time‐of‐day control of mitochondria regulates NLRP3 inflammasome activation in macrophages faseb.onlinelibrary.wiley.com/doi/10.1096/...
Time‐of‐day control of mitochondria regulates NLRP3 inflammasome activation in macrophages
The circadian clock, orchestrated by BMAL1, regulates the expression of Nlrp3 and Il1b in response to lipopolysaccharide (LPS), causing time-of-day production of pro-IL-1β. Mitochondria exhibit time-....
faseb.onlinelibrary.wiley.com
January 15, 2025 at 12:31 AM
More nice research from Annie Curtis’ lab on the circadian rhythm and the
#immunometabolism of macrophages.
#immunosky #mitochondria #inflammasome
Time‐of‐day control of mitochondria regulates NLRP3 inflammasome activation in macrophages faseb.onlinelibrary.wiley.com/doi/10.1096/...
#immunometabolism of macrophages.
#immunosky #mitochondria #inflammasome
Time‐of‐day control of mitochondria regulates NLRP3 inflammasome activation in macrophages faseb.onlinelibrary.wiley.com/doi/10.1096/...
Reposted by Immunometabolism forum
Exciting work from Sue Kaech’s lab @tcellogic.bsky.social
Tissue specific metabolites like #BileAcids in #Liver affect #CD8Tcell tumour responses
#immunometabolism #immunosky
Bile acid synthesis impedes tumor-specific T cell responses during liver cancer www.science.org/doi/10.1126/...
Tissue specific metabolites like #BileAcids in #Liver affect #CD8Tcell tumour responses
#immunometabolism #immunosky
Bile acid synthesis impedes tumor-specific T cell responses during liver cancer www.science.org/doi/10.1126/...
Bile acid synthesis impedes tumor-specific T cell responses during liver cancer
The metabolic landscape of cancer greatly influences antitumor immunity, yet it remains unclear how organ-specific metabolites in the tumor microenvironment influence immunosurveillance. We found that...
www.science.org
January 15, 2025 at 1:15 AM
Exciting work from Sue Kaech’s lab @tcellogic.bsky.social
Tissue specific metabolites like #BileAcids in #Liver affect #CD8Tcell tumour responses
#immunometabolism #immunosky
Bile acid synthesis impedes tumor-specific T cell responses during liver cancer www.science.org/doi/10.1126/...
Tissue specific metabolites like #BileAcids in #Liver affect #CD8Tcell tumour responses
#immunometabolism #immunosky
Bile acid synthesis impedes tumor-specific T cell responses during liver cancer www.science.org/doi/10.1126/...
Reposted by Immunometabolism forum
Lots of interest in how to maintain healthy mitochondria for effective cell therapy, like #NKcells for cancer immunotherapy. Some interesting clues in this article.
#immunosky #immunometabolism
Triacylglycerol mobilization underpins mitochondrial stress recovery
www.nature.com/articles/s41...
#immunosky #immunometabolism
Triacylglycerol mobilization underpins mitochondrial stress recovery
www.nature.com/articles/s41...
Triacylglycerol mobilization underpins mitochondrial stress recovery - Nature Cell Biology
Baker et al. show that mitochondrial stress recovery requires mobilization of lipid droplet triacylglycerol stores to facilitate cardiolipin biosynthesis and mitochondrial biogenesis.
www.nature.com
January 15, 2025 at 1:30 AM
Lots of interest in how to maintain healthy mitochondria for effective cell therapy, like #NKcells for cancer immunotherapy. Some interesting clues in this article.
#immunosky #immunometabolism
Triacylglycerol mobilization underpins mitochondrial stress recovery
www.nature.com/articles/s41...
#immunosky #immunometabolism
Triacylglycerol mobilization underpins mitochondrial stress recovery
www.nature.com/articles/s41...
Reposted by Immunometabolism forum
AMPK-regulated glycerol excretion maintains metabolic crosstalk between reductive and energetic stress www.nature.com/articles/s41...
AMPK-regulated glycerol excretion maintains metabolic crosstalk between reductive and energetic stress - Nature Cell Biology
Zhai, Yang et al. report a central role for AMPK in regulating aldolase B-mediated glycerol synthesis and excretion under hypoxia as a mechanism to balance the trade-off between reductive and energy s...
www.nature.com
January 4, 2025 at 12:15 PM
AMPK-regulated glycerol excretion maintains metabolic crosstalk between reductive and energetic stress www.nature.com/articles/s41...
Reposted by Immunometabolism forum
#Immunometabolism role for Pyrimidine synthesis enzyme CTP synthetase-1.
CTPS1 deaminates IRF3 and suppresses IFN response; important implications for antiviral #immunology?
Yes indeed…. authors show that loss of CTPS1 elevates antiviral immune response in
www.cell.com/immunity/ful...
CTPS1 deaminates IRF3 and suppresses IFN response; important implications for antiviral #immunology?
Yes indeed…. authors show that loss of CTPS1 elevates antiviral immune response in
www.cell.com/immunity/ful...
Pyrimidine synthesis enzyme CTP synthetase 1 suppresses antiviral interferon induction by deamidating IRF3
The intersection between cellular metabolism and innate immunity lacks understanding. Here, Rao and Qin et al. report that the metabolic enzyme, CTP synthetase 1, deamidates IRF3 to limit interferon induction, independent of its role in pyrimidine synthesis. This reveals how a key metabolic enzyme directly regulates innate immune activation.
www.cell.com
January 5, 2025 at 2:19 AM
#Immunometabolism role for Pyrimidine synthesis enzyme CTP synthetase-1.
CTPS1 deaminates IRF3 and suppresses IFN response; important implications for antiviral #immunology?
Yes indeed…. authors show that loss of CTPS1 elevates antiviral immune response in
www.cell.com/immunity/ful...
CTPS1 deaminates IRF3 and suppresses IFN response; important implications for antiviral #immunology?
Yes indeed…. authors show that loss of CTPS1 elevates antiviral immune response in
www.cell.com/immunity/ful...
Reposted by Immunometabolism forum
Authors use an elegant transgenic model to demonstrate that acute oral administration of metformin targets mitochondrial complex I to lower blood glucose.
A crucial contribution to the debate about the mechanisms of action of #metformin.
#metabolism #glucose
doi.org/10.1126/scia...
A crucial contribution to the debate about the mechanisms of action of #metformin.
#metabolism #glucose
doi.org/10.1126/scia...
Metformin targets mitochondrial complex I to lower blood glucose levels
Acute oral metformin administration lowers blood glucose levels by targeting mitochondrial complex I.
doi.org
January 5, 2025 at 2:27 AM
Authors use an elegant transgenic model to demonstrate that acute oral administration of metformin targets mitochondrial complex I to lower blood glucose.
A crucial contribution to the debate about the mechanisms of action of #metformin.
#metabolism #glucose
doi.org/10.1126/scia...
A crucial contribution to the debate about the mechanisms of action of #metformin.
#metabolism #glucose
doi.org/10.1126/scia...
Reposted by Immunometabolism forum
Another important example of lactylation controlling metabolic pathways; stabilisation of TFEB to increase lysosomal activity.
Will be interesting to see if this mechanism plays a role in #immunometabolism #immunology responses.
rupress.org/jcb/article/...
Will be interesting to see if this mechanism plays a role in #immunometabolism #immunology responses.
rupress.org/jcb/article/...
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity | Journal of Cell Biology | Rockefeller University Press
Posttranslational modifications play a crucial role in regulating autophagy and lysosome–related transcription factor TFEB. Huang et al. find the increase
rupress.org
January 5, 2025 at 2:48 AM
Another important example of lactylation controlling metabolic pathways; stabilisation of TFEB to increase lysosomal activity.
Will be interesting to see if this mechanism plays a role in #immunometabolism #immunology responses.
rupress.org/jcb/article/...
Will be interesting to see if this mechanism plays a role in #immunometabolism #immunology responses.
rupress.org/jcb/article/...
Reposted by Immunometabolism forum
“Glutamine sensing licenses cholesterol synthesis”
#glutamine interacts with SCAP to alter the ER to Golgi trafficking needed to activate #SREBP transcriptional response.
www.embopress.org/doi/full/10....
Is this relevant to #immunometabolism, such as SREBP-dependent #NKcell responses?
#glutamine interacts with SCAP to alter the ER to Golgi trafficking needed to activate #SREBP transcriptional response.
www.embopress.org/doi/full/10....
Is this relevant to #immunometabolism, such as SREBP-dependent #NKcell responses?
Glutamine sensing licenses cholesterol synthesis | The EMBO Journal
imageimageWhether cholesterol biosynthesis can be adjusted to the availability of input carbon
sources remains unclear. This study demonstrates that glutamine is directly sensed
by and required for ac...
www.embopress.org
January 5, 2025 at 11:10 PM
“Glutamine sensing licenses cholesterol synthesis”
#glutamine interacts with SCAP to alter the ER to Golgi trafficking needed to activate #SREBP transcriptional response.
www.embopress.org/doi/full/10....
Is this relevant to #immunometabolism, such as SREBP-dependent #NKcell responses?
#glutamine interacts with SCAP to alter the ER to Golgi trafficking needed to activate #SREBP transcriptional response.
www.embopress.org/doi/full/10....
Is this relevant to #immunometabolism, such as SREBP-dependent #NKcell responses?
Reposted by Immunometabolism forum
Metabolic #plasticity to Slc1a5 loss involving upregulation of macropinocytosis.
Important also for #immune cells to support glutamine requirements?
#immunometabolism
“Macropinocytosis mediates resistance to loss of glutamine transport in TNBC” www.embopress.org/doi/full/10....
Important also for #immune cells to support glutamine requirements?
#immunometabolism
“Macropinocytosis mediates resistance to loss of glutamine transport in TNBC” www.embopress.org/doi/full/10....
January 5, 2025 at 11:38 PM
Metabolic #plasticity to Slc1a5 loss involving upregulation of macropinocytosis.
Important also for #immune cells to support glutamine requirements?
#immunometabolism
“Macropinocytosis mediates resistance to loss of glutamine transport in TNBC” www.embopress.org/doi/full/10....
Important also for #immune cells to support glutamine requirements?
#immunometabolism
“Macropinocytosis mediates resistance to loss of glutamine transport in TNBC” www.embopress.org/doi/full/10....
Reposted by Immunometabolism forum
📢Preprint alert! Very excited to share the first preprint from the lab spearheaded by stellar postdoc Eloïse Marques. An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo. 1/n
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo
Impaired mitochondrial bioenergetics in macrophages can drive hyperinflammatory cytokine responses, but whether this may also be caused by inherited mtDNA mutations is unknown. Here, we address this q...
www.biorxiv.org
January 6, 2025 at 9:34 AM
📢Preprint alert! Very excited to share the first preprint from the lab spearheaded by stellar postdoc Eloïse Marques. An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo. 1/n
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Immunometabolism forum
Interesting new oxysterol research from Jason Cyster’s lab.
EBI2 (GPR183) and oxysterol ligand 7α,25-HC are required for lymphocyte homing to inflamed LNs.
#immunology #oxysterols
Inflammation switches the chemoattractant requirements for naive lymphocyte entry into LN www.cell.com/cell/fulltex...
EBI2 (GPR183) and oxysterol ligand 7α,25-HC are required for lymphocyte homing to inflamed LNs.
#immunology #oxysterols
Inflammation switches the chemoattractant requirements for naive lymphocyte entry into LN www.cell.com/cell/fulltex...
Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes
Lymph node swelling is a well-known symptom of infection. A shift in the chemoattractant code controls lymphocyte recruitment from blood into inflamed lymph nodes, allowing lymphocytes to accumulate so that even rare antigen-specific cells can encounter their activating antigen.
www.cell.com
January 6, 2025 at 10:13 AM
Interesting new oxysterol research from Jason Cyster’s lab.
EBI2 (GPR183) and oxysterol ligand 7α,25-HC are required for lymphocyte homing to inflamed LNs.
#immunology #oxysterols
Inflammation switches the chemoattractant requirements for naive lymphocyte entry into LN www.cell.com/cell/fulltex...
EBI2 (GPR183) and oxysterol ligand 7α,25-HC are required for lymphocyte homing to inflamed LNs.
#immunology #oxysterols
Inflammation switches the chemoattractant requirements for naive lymphocyte entry into LN www.cell.com/cell/fulltex...
Reposted by Immunometabolism forum
New review article written by Cristhiane Favero de Aguiar and Carrie Corkish from my lab. They did a great job.
www.nature.com/articles/s41...
#SingleCell #Immunometabolism
#ImmunoSky
Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level
www.nature.com/articles/s41...
#SingleCell #Immunometabolism
#ImmunoSky
Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level
November 30, 2024 at 11:00 PM
New review article written by Cristhiane Favero de Aguiar and Carrie Corkish from my lab. They did a great job.
www.nature.com/articles/s41...
#SingleCell #Immunometabolism
#ImmunoSky
Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level
www.nature.com/articles/s41...
#SingleCell #Immunometabolism
#ImmunoSky
Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level
Reposted by Immunometabolism forum
Interesting new research from Antoine Marçais’ lab showing a central role for pyruvate and the Citrate-Malate Shuttle (non-canonical TCA cycle) in human NK cells.
#immunology #NKcells #Immunometabolism
doi.org/10.1038/s422...
See our commentary article here:
www.nature.com/articles/s42...
#immunology #NKcells #Immunometabolism
doi.org/10.1038/s422...
See our commentary article here:
www.nature.com/articles/s42...
Natural killer loops: pyruvate in, lactate out - Nature Metabolism
Resting human CD56Dim natural killer cells utilize exogenous pyruvate to support energy metabolism. A new study shows that these cells take up exogenous pyruvate, which regenerates cytosolic NAD+ via ...
www.nature.com
January 3, 2025 at 12:30 PM
Interesting new research from Antoine Marçais’ lab showing a central role for pyruvate and the Citrate-Malate Shuttle (non-canonical TCA cycle) in human NK cells.
#immunology #NKcells #Immunometabolism
doi.org/10.1038/s422...
See our commentary article here:
www.nature.com/articles/s42...
#immunology #NKcells #Immunometabolism
doi.org/10.1038/s422...
See our commentary article here:
www.nature.com/articles/s42...
Reposted by Immunometabolism forum
And from National University of Ireland Maynooth (NUIM), Eimear Ryan from @andyhogan82.bsky.social lab will present her work at the December @immunometforum.bsky.social on #MAITcell #metabolism.
#immmunosky #immunoology #immunometabolism
#immmunosky #immunoology #immunometabolism
December 10, 2024 at 3:54 PM
And from National University of Ireland Maynooth (NUIM), Eimear Ryan from @andyhogan82.bsky.social lab will present her work at the December @immunometforum.bsky.social on #MAITcell #metabolism.
#immmunosky #immunoology #immunometabolism
#immmunosky #immunoology #immunometabolism
Reposted by Immunometabolism forum
From Leiden in the Netherlands, @thiagoapatente.bsky.social from Bart Everts lab will present work at the December @immunometforum.bsky.social on #DCs and #Tregs.
#immmunosky #immunoology #immunometabolism
#immmunosky #immunoology #immunometabolism
December 10, 2024 at 3:54 PM
From Leiden in the Netherlands, @thiagoapatente.bsky.social from Bart Everts lab will present work at the December @immunometforum.bsky.social on #DCs and #Tregs.
#immmunosky #immunoology #immunometabolism
#immmunosky #immunoology #immunometabolism
Reposted by Immunometabolism forum
From Madrid in Spain, Gillian Dunphy from the @sancholab.bsky.social lab will present her work c on #macrophages and #mitochondria.
#immmunosky #immunoology #immunometabolism
#immmunosky #immunoology #immunometabolism
December 10, 2024 at 3:54 PM
From Madrid in Spain, Gillian Dunphy from the @sancholab.bsky.social lab will present her work c on #macrophages and #mitochondria.
#immmunosky #immunoology #immunometabolism
#immmunosky #immunoology #immunometabolism
Reposted by Immunometabolism forum
The December @immunometforum.bsky.social will
take place this Friday with three great early career researcher presenting:
🧵1/4
#immmunosky #immunoology #immunometabolism
take place this Friday with three great early career researcher presenting:
🧵1/4
#immmunosky #immunoology #immunometabolism
December 10, 2024 at 3:54 PM
The December @immunometforum.bsky.social will
take place this Friday with three great early career researcher presenting:
🧵1/4
#immmunosky #immunoology #immunometabolism
take place this Friday with three great early career researcher presenting:
🧵1/4
#immmunosky #immunoology #immunometabolism
Some useful starter packs 👍
Cancer Immunology: bsky.app/starter-pack...
A repertoire of immunologists II: bsky.app/starter-pack...
Immunometabolism: bsky.app/starter-pack...
A repertoire of immunologists: bsky.app/starter-pack...
Cancer Immunology: bsky.app/starter-pack...
A repertoire of immunologists II: bsky.app/starter-pack...
Immunometabolism: bsky.app/starter-pack...
A repertoire of immunologists: bsky.app/starter-pack...
November 18, 2024 at 9:46 PM
Some useful starter packs 👍
Cancer Immunology: bsky.app/starter-pack...
A repertoire of immunologists II: bsky.app/starter-pack...
Immunometabolism: bsky.app/starter-pack...
A repertoire of immunologists: bsky.app/starter-pack...
Cancer Immunology: bsky.app/starter-pack...
A repertoire of immunologists II: bsky.app/starter-pack...
Immunometabolism: bsky.app/starter-pack...
A repertoire of immunologists: bsky.app/starter-pack...
Reposted by Immunometabolism forum
Prostaglandin E2-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells
#immunometabolism #TME #immunosuppression
www.nature.com/articles/s41...
#immunometabolism #TME #immunosuppression
www.nature.com/articles/s41...
Prostaglandin E2-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells - Nature Communications
Mechanisms of prostaglandin E2 (PGE2)-mediated immunosuppression in the tumor microenvironment (TME) have been previously reported. Here, the authors profile PGE2 functions in human cancer, suggesting...
www.nature.com
November 16, 2024 at 10:43 PM
Prostaglandin E2-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells
#immunometabolism #TME #immunosuppression
www.nature.com/articles/s41...
#immunometabolism #TME #immunosuppression
www.nature.com/articles/s41...
Reposted by Immunometabolism forum
Interesting link between high glucose in T2D patients and impaired T cells responses towards virus.
#LipidPeroxidation
#TcellSignalling
#T2D
Hyperglycemia-triggered lipid peroxidation destabilizes STAT4 and impairs anti-viral Th1 responses in type 2 diabetes
www.sciencedirect.com/science/arti...
#LipidPeroxidation
#TcellSignalling
#T2D
Hyperglycemia-triggered lipid peroxidation destabilizes STAT4 and impairs anti-viral Th1 responses in type 2 diabetes
www.sciencedirect.com/science/arti...
November 17, 2024 at 10:04 PM
Interesting link between high glucose in T2D patients and impaired T cells responses towards virus.
#LipidPeroxidation
#TcellSignalling
#T2D
Hyperglycemia-triggered lipid peroxidation destabilizes STAT4 and impairs anti-viral Th1 responses in type 2 diabetes
www.sciencedirect.com/science/arti...
#LipidPeroxidation
#TcellSignalling
#T2D
Hyperglycemia-triggered lipid peroxidation destabilizes STAT4 and impairs anti-viral Th1 responses in type 2 diabetes
www.sciencedirect.com/science/arti...
Reposted by Immunometabolism forum
Study argues glutamine diminishes activation and recruitment of neutrophils
#Neutrophils #glutamine #mitochondria #glutathione #transglutaminase2
“Glutamine modulates neutrophil recruitment and effector functions during sterile inflammation”
doi.org/10.1093/jleu...
#Neutrophils #glutamine #mitochondria #glutathione #transglutaminase2
“Glutamine modulates neutrophil recruitment and effector functions during sterile inflammation”
doi.org/10.1093/jleu...
Glutamine modulates neutrophil recruitment and effector functions during sterile inflammation
Glutamine modulates neutrophil responses during sterile inflammation.
doi.org
November 17, 2024 at 10:17 PM
Study argues glutamine diminishes activation and recruitment of neutrophils
#Neutrophils #glutamine #mitochondria #glutathione #transglutaminase2
“Glutamine modulates neutrophil recruitment and effector functions during sterile inflammation”
doi.org/10.1093/jleu...
#Neutrophils #glutamine #mitochondria #glutathione #transglutaminase2
“Glutamine modulates neutrophil recruitment and effector functions during sterile inflammation”
doi.org/10.1093/jleu...
Reposted by Immunometabolism forum
Summary of @lydialynch
and Aaron Douglas’ recent exciting paper
#IL17 #gdTcells #lipogenesis #AdiposeTissue
Fat keeps metabolism in tune and on time using an inflammatory immune protein www.nature.com/articles/d41...
Actual paper here www.nature.com/articles/s41...
and Aaron Douglas’ recent exciting paper
#IL17 #gdTcells #lipogenesis #AdiposeTissue
Fat keeps metabolism in tune and on time using an inflammatory immune protein www.nature.com/articles/d41...
Actual paper here www.nature.com/articles/s41...
Fat keeps metabolism in tune and on time using an inflammatory immune protein
Immune cells that release the molecule IL-17A help to drive the metabolic rhythms of fat.
www.nature.com
November 17, 2024 at 10:51 PM
Summary of @lydialynch
and Aaron Douglas’ recent exciting paper
#IL17 #gdTcells #lipogenesis #AdiposeTissue
Fat keeps metabolism in tune and on time using an inflammatory immune protein www.nature.com/articles/d41...
Actual paper here www.nature.com/articles/s41...
and Aaron Douglas’ recent exciting paper
#IL17 #gdTcells #lipogenesis #AdiposeTissue
Fat keeps metabolism in tune and on time using an inflammatory immune protein www.nature.com/articles/d41...
Actual paper here www.nature.com/articles/s41...