Hyman Lab
@hymanlab.bsky.social
Science and fun from the lab of Tony Hyman at the MPI-CBG @mpicbg.bsky.social. Tweets by Hymanlab members.
https://hymanlab.org/
https://hymanlab.org/
Reposted by Hyman Lab
CD-CODE 2.0 is now published in @narjournal.bsky.social 🤩
CD-CODE 2.0 stores #biomolecular #condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies
👀 doi.org/10.1093/nar/...
CD-CODE 2.0 stores #biomolecular #condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies
👀 doi.org/10.1093/nar/...
November 14, 2025 at 1:20 PM
CD-CODE 2.0 is now published in @narjournal.bsky.social 🤩
CD-CODE 2.0 stores #biomolecular #condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies
👀 doi.org/10.1093/nar/...
CD-CODE 2.0 stores #biomolecular #condensates and their #protein and nucleic acid components and now includes repository of 🦠 infectious condensates, 💊 condensate-modulating compounds, and 🩺 condensatopathies
👀 doi.org/10.1093/nar/...
Reposted by Hyman Lab
The Lab of Stephan Grill at MPI-CBG has finally made it to Bluesky and we also have a brand new homepage: grill-lab.org
Check it out.
Check it out.
November 6, 2025 at 1:09 PM
The Lab of Stephan Grill at MPI-CBG has finally made it to Bluesky and we also have a brand new homepage: grill-lab.org
Check it out.
Check it out.
We had a good line up of speakers at the 50 years anniversary meeting of the german society of cell biology @dgz.bsky.social in Heidelberg. Tony gave the plenary, Koichiro talked about spatial control of P granules and Silja received a price for her Master thesis and gave a talk. Congratulations!
October 29, 2025 at 3:16 PM
We had a good line up of speakers at the 50 years anniversary meeting of the german society of cell biology @dgz.bsky.social in Heidelberg. Tony gave the plenary, Koichiro talked about spatial control of P granules and Silja received a price for her Master thesis and gave a talk. Congratulations!
Congratulations to our PhD student David @rnadavid.bsky.social for his successful defense of his PhD thesis! @mpi-cbg.de imprs.mpi-cbg.de
As you see the lab was very creative with his hat! David gave his insights on the nucleocapsid protein and even better arranged a great buffet for celebrations!
As you see the lab was very creative with his hat! David gave his insights on the nucleocapsid protein and even better arranged a great buffet for celebrations!
October 29, 2025 at 2:07 PM
Congratulations to our PhD student David @rnadavid.bsky.social for his successful defense of his PhD thesis! @mpi-cbg.de imprs.mpi-cbg.de
As you see the lab was very creative with his hat! David gave his insights on the nucleocapsid protein and even better arranged a great buffet for celebrations!
As you see the lab was very creative with his hat! David gave his insights on the nucleocapsid protein and even better arranged a great buffet for celebrations!
Reposted by Hyman Lab
Lipid imaging on the cover of @nature.com! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article: www.nature.com/articles/s41...
October 9, 2025 at 9:01 AM
Lipid imaging on the cover of @nature.com! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article: www.nature.com/articles/s41...
🤌
IG Nobel Prize in #Physics 2025 to @mpipks.bsky.social researchers for elucidating the phase behaviour of cacio e pepe sauce. The work highlights how physics can also be applied to solve daily-life problems!
nature.com/articles/d41586-025-03045-0
nature.com/articles/d41586-025-03045-0
Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research
The annual awards are a celebration of weird but thought-provoking science.
nature.com
September 19, 2025 at 3:05 PM
🤌
Have a look at Lars @larshubatsch.bsky.social reviewed preprint in @elife.bsky.social and learn about the kinetics of molecule transport across interfaces of condensates!
Paper alert!🧪
We derive a theory that underpins interface resistance with a physical foundation and look at how it changes droplet growth and recovery kinetics! Awesome collab with @bosste.bsky.social Tyler Harmon @hymanlab.bsky.social @m-pol.bsky.social and Frank Jülicher @mpipks.bsky.social 1/4
We derive a theory that underpins interface resistance with a physical foundation and look at how it changes droplet growth and recovery kinetics! Awesome collab with @bosste.bsky.social Tyler Harmon @hymanlab.bsky.social @m-pol.bsky.social and Frank Jülicher @mpipks.bsky.social 1/4
Transport kinetics across interfaces between coexisting liquid phases
elifesciences.org
September 16, 2025 at 4:25 PM
Have a look at Lars @larshubatsch.bsky.social reviewed preprint in @elife.bsky.social and learn about the kinetics of molecule transport across interfaces of condensates!
Congratulations to Patrick and his team!
Tremendous work carried out over the last years @mpi-cbg.de and @poldresden.bsky.social as collaboration between Hyman lab, Brugues lab and Andrei Shevchenko
Tremendous work carried out over the last years @mpi-cbg.de and @poldresden.bsky.social as collaboration between Hyman lab, Brugues lab and Andrei Shevchenko
Patrick's paper is finally out, a label-free method to measure the composition of multicomponent biomolecular condensates!
September 5, 2025 at 10:06 AM
Congratulations to Patrick and his team!
Tremendous work carried out over the last years @mpi-cbg.de and @poldresden.bsky.social as collaboration between Hyman lab, Brugues lab and Andrei Shevchenko
Tremendous work carried out over the last years @mpi-cbg.de and @poldresden.bsky.social as collaboration between Hyman lab, Brugues lab and Andrei Shevchenko
Reposted by Hyman Lab
This is an amazing piece of work! It was a true pleasure seeing this story come together.
@mpi-cbg.de going on a streak of @nature.com papers!
@mpi-cbg.de going on a streak of @nature.com papers!
Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...
Mechanical forces drive evolutionary change
A small tissue fold present in fruit fly embryos buffers mechanical stresses and may have evolved in response to mechanical forces.
www.mpi-cbg.de
September 3, 2025 at 5:46 PM
This is an amazing piece of work! It was a true pleasure seeing this story come together.
@mpi-cbg.de going on a streak of @nature.com papers!
@mpi-cbg.de going on a streak of @nature.com papers!
Reposted by Hyman Lab
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Hyman Lab
The recent publication from MtL fellow @hymanlab.bsky.social has described a quantitative framework for condensate stability and dissolution, in the context of RNA binding protein MEX-5 and P-granules. Congratulations to MtL Student Silja Zedlitz for being a co-author!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
A mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro | PNAS
MEX-5 regulates the formation and dissolution of P granules in Caenorhabditis elegans
embryos, yet the thermodynamic basis of its activity remains ...
www.pnas.org
July 16, 2025 at 7:05 AM
The recent publication from MtL fellow @hymanlab.bsky.social has described a quantitative framework for condensate stability and dissolution, in the context of RNA binding protein MEX-5 and P-granules. Congratulations to MtL Student Silja Zedlitz for being a co-author!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Hyman Lab
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Novel Research in Biological Artificial Intelligence
Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.
www.mpi-cbg.de
June 26, 2025 at 11:26 AM
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Reposted by Hyman Lab
How to spy on condensates: technology feature in @natmethods.nature.com on self-organization and collective properties of condensates with quotes from Anthony Hyman @hymanlab.bsky.social @mpi-cbg.de, @brangwynnelab.bsky.social, and many more. www.nature.com/articles/s41...
How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
www.nature.com
June 25, 2025 at 7:50 AM
How to spy on condensates: technology feature in @natmethods.nature.com on self-organization and collective properties of condensates with quotes from Anthony Hyman @hymanlab.bsky.social @mpi-cbg.de, @brangwynnelab.bsky.social, and many more. www.nature.com/articles/s41...
Reposted by Hyman Lab
Dresden scientists @thegutmann.bsky.social and @rnadavid.bsky.social from the @hymanlab.bsky.social discover a new strategy used by the SARS-CoV-2 virus to hide from the body’s DNA immune detection system. Now published in @pnas.org. www.mpi-cbg.de/news-outreac...
June 24, 2025 at 10:54 AM
Dresden scientists @thegutmann.bsky.social and @rnadavid.bsky.social from the @hymanlab.bsky.social discover a new strategy used by the SARS-CoV-2 virus to hide from the body’s DNA immune detection system. Now published in @pnas.org. www.mpi-cbg.de/news-outreac...
How could SARS-COV-2 evade detection by host cells?
Read the new paper from Theresia @thegutmann.bsky.social
and David @rnadavid.bsky.social discussing how the nucleocapsid protein prevents recognition of the innate immunity sensor cGAS
Congratulations!!!
Read the new paper from Theresia @thegutmann.bsky.social
and David @rnadavid.bsky.social discussing how the nucleocapsid protein prevents recognition of the innate immunity sensor cGAS
Congratulations!!!
Excited to share our latest work out in @pnas.org! We show that the #SARSCoV2 nucleocapsid protein directly prevents DNA recognition of the immune sensor #cGAS by competing for DNA, which may delay early innate immune responses during infection. www.pnas.org/doi/epub/10.... #innateimmunity
June 24, 2025 at 8:22 AM
How could SARS-COV-2 evade detection by host cells?
Read the new paper from Theresia @thegutmann.bsky.social
and David @rnadavid.bsky.social discussing how the nucleocapsid protein prevents recognition of the innate immunity sensor cGAS
Congratulations!!!
Read the new paper from Theresia @thegutmann.bsky.social
and David @rnadavid.bsky.social discussing how the nucleocapsid protein prevents recognition of the innate immunity sensor cGAS
Congratulations!!!
Reposted by Hyman Lab
Big news 🎉 We are excited to announce the new TUD graduate school "Biomolecular Condensates: From Physics to Biological Functions", with 12 members from PoL! Through this school, we will train a new generation of scientists working on #condensates at the interphase between theory and experiments 🤓⤵️
Hochaktuelles Themenfeld an der Schnittstelle von Physik, Biologie und Polymerforschung: Die @dfg.de fördert ab 2026 mit rund 7 Millionen Euro ein neues Graduiertenkolleg zur Erforschung biomolekularer Kondensate in #Dresden. 🔬
ℹ️ tu-dresden.de/tu-dresden/n...
ℹ️ tu-dresden.de/tu-dresden/n...
June 18, 2025 at 10:59 AM
Big news 🎉 We are excited to announce the new TUD graduate school "Biomolecular Condensates: From Physics to Biological Functions", with 12 members from PoL! Through this school, we will train a new generation of scientists working on #condensates at the interphase between theory and experiments 🤓⤵️
Reposted by Hyman Lab
Visit us during the Dresden Science Night on June 20th in the Faculty of Physics @tudresden.bsky.social (Hermann-Krone-Bau, Nöthnitzer Straße 61) and explore the physics of life! Looking forward to see you! www.mpi-cbg.de/news-outreac...
June 18, 2025 at 12:23 PM
Visit us during the Dresden Science Night on June 20th in the Faculty of Physics @tudresden.bsky.social (Hermann-Krone-Bau, Nöthnitzer Straße 61) and explore the physics of life! Looking forward to see you! www.mpi-cbg.de/news-outreac...
Reposted by Hyman Lab
We're excited to welcome Dresden's scientific community to the GBM Compact Meeting in Frankfurt! #CodensateBiology
gbm-compact.org
gbm-compact.org
June 16, 2025 at 12:11 PM
We're excited to welcome Dresden's scientific community to the GBM Compact Meeting in Frankfurt! #CodensateBiology
gbm-compact.org
gbm-compact.org
The german research foundation DFG will fund the new graduate school for
"Biomolecular Condensates: from physics to biological function" here in Dresden
This new graduate school is part of 18 new graduate schools funded by the DFG in germany!
"Biomolecular Condensates: from physics to biological function" here in Dresden
This new graduate school is part of 18 new graduate schools funded by the DFG in germany!
Förderentscheidung für 18 neue #Graduiertenkollegs, darunter 4 internationale Verbünde mit Partnern in den USA, Italien, Kanada und Frankreich. Themen reichen von klimaneutralem Stahl bis zur Erforschung von Infektionserkrankungen . ➡️ www.dfg.de/de/service/p...
June 16, 2025 at 8:37 AM
The german research foundation DFG will fund the new graduate school for
"Biomolecular Condensates: from physics to biological function" here in Dresden
This new graduate school is part of 18 new graduate schools funded by the DFG in germany!
"Biomolecular Condensates: from physics to biological function" here in Dresden
This new graduate school is part of 18 new graduate schools funded by the DFG in germany!
Reposted by Hyman Lab
The latest release was supported by the #condesathon joined by @mpi-cbg.de condensate community🤩
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
June 11, 2025 at 1:33 PM
The latest release was supported by the #condesathon joined by @mpi-cbg.de condensate community🤩
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
Big #thankyou to all the participants from
@hymanlab.bsky.social, @tothpetroczylab.bsky.social and von Appen labs for your support and enthusiasm!💜
We had great fun with the lab!
Thirty-six institute staff members in nine tems participated in the REWE Team Challenge Dresden on Wednesday evening, May 28. Congratulations to all participants! 🎉 www.mpi-cbg.de/news-outreac...
MPI-CBG participates in Dresden 5K running event
Nine teams ran REWE Team Challenge Dresden 2025
www.mpi-cbg.de
June 4, 2025 at 11:37 AM
We had great fun with the lab!
Reposted by Hyman Lab
Condensates Inside Condensates—Triggering Disease?
New Insights into TDP-43 Condensation and Neurodegeneration. Publication from the @hymanlab.bsky.social in @cellpress.bsky.social, first author: @xiaoyan52802927.bsky.social www.mpi-cbg.de/news-outreac...
New Insights into TDP-43 Condensation and Neurodegeneration. Publication from the @hymanlab.bsky.social in @cellpress.bsky.social, first author: @xiaoyan52802927.bsky.social www.mpi-cbg.de/news-outreac...
Condensates Inside Condensates—Triggering Disease?
New Insights into TDP-43 Condensation and Neurodegeneration
www.mpi-cbg.de
May 28, 2025 at 3:07 PM
Condensates Inside Condensates—Triggering Disease?
New Insights into TDP-43 Condensation and Neurodegeneration. Publication from the @hymanlab.bsky.social in @cellpress.bsky.social, first author: @xiaoyan52802927.bsky.social www.mpi-cbg.de/news-outreac...
New Insights into TDP-43 Condensation and Neurodegeneration. Publication from the @hymanlab.bsky.social in @cellpress.bsky.social, first author: @xiaoyan52802927.bsky.social www.mpi-cbg.de/news-outreac...
Reposted by Hyman Lab
Watch the related Science Sketch video: youtu.be/uBpPMyVTj5c?..., created by @marionamec.bsky.social
Molecule Disarms Cellular Stress Granules Linked to ALS
YouTube video by MPI-CBG
youtu.be
May 27, 2025 at 2:17 PM
Watch the related Science Sketch video: youtu.be/uBpPMyVTj5c?..., created by @marionamec.bsky.social
Reposted by Hyman Lab
A team @mpi-cbg.de from @hymanlab.bsky.social & the @edinburghup.bsky.social (Richard Wheeler group) has identified the molecule lipoamide that can prevent the formation of pathological stress granules - protein-rich condensates associated with cellular stress and ALS. www.mpi-cbg.de/news-outreac...
Molecule Disarms Cellular Stress Granules Linked to ALS
Discovery by researchers in Dresden and Edinburgh points to new understanding of the onset of ALS.
www.mpi-cbg.de
May 27, 2025 at 2:14 PM
A team @mpi-cbg.de from @hymanlab.bsky.social & the @edinburghup.bsky.social (Richard Wheeler group) has identified the molecule lipoamide that can prevent the formation of pathological stress granules - protein-rich condensates associated with cellular stress and ALS. www.mpi-cbg.de/news-outreac...