Sarah Hainer
@hainerlab.bsky.social
Assistant Prof @PittBioSci studying transcription dynamics and chromatin biology | passionate about equity in STEM | she/her
Reposted by Sarah Hainer
Comment period ends on Monday for a proposed rule change that would terminate student visas after 4 years. It also puts limits on exchange visitors and reps of foreign media, and shortens the length of time at the end of the visa from 60 days to 30 days.
www.federalregister.gov/documents/20...
www.federalregister.gov/documents/20...
Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media
Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...
www.federalregister.gov
September 27, 2025 at 12:18 PM
Comment period ends on Monday for a proposed rule change that would terminate student visas after 4 years. It also puts limits on exchange visitors and reps of foreign media, and shortens the length of time at the end of the visa from 60 days to 30 days.
www.federalregister.gov/documents/20...
www.federalregister.gov/documents/20...
New preprint is up, led by former postdoc Braulio Bonilla.
We know these remodelers regulate nucleosome positions and occupancy, but do they have a role in regulating higher order chromatin structure? We take a peek for BAF and INO80C.
www.biorxiv.org/content/10.1...
We know these remodelers regulate nucleosome positions and occupancy, but do they have a role in regulating higher order chromatin structure? We take a peek for BAF and INO80C.
www.biorxiv.org/content/10.1...
esBAF and INO80C fine-tune subcompartments and differentially regulate enhancer-promoter interactions
The genome is compacted in the nucleus through a hierarchical chromatin organization, ranging from chromosome territories to compartments, topologically associating domains (TADs), and individual nucl...
www.biorxiv.org
September 18, 2025 at 3:00 PM
New preprint is up, led by former postdoc Braulio Bonilla.
We know these remodelers regulate nucleosome positions and occupancy, but do they have a role in regulating higher order chromatin structure? We take a peek for BAF and INO80C.
www.biorxiv.org/content/10.1...
We know these remodelers regulate nucleosome positions and occupancy, but do they have a role in regulating higher order chromatin structure? We take a peek for BAF and INO80C.
www.biorxiv.org/content/10.1...
Reposted by Sarah Hainer
🧬 Transcription elongation by RNA polymerase II relies on a web of elongation factors. Our new work shows how IWS1 acts as a modular scaffold to stabilize & stimulate elongation. Fantastic work by Della Syau! www.biorxiv.org/content/10.1...
August 29, 2025 at 10:14 AM
🧬 Transcription elongation by RNA polymerase II relies on a web of elongation factors. Our new work shows how IWS1 acts as a modular scaffold to stabilize & stimulate elongation. Fantastic work by Della Syau! www.biorxiv.org/content/10.1...
Our collaborative paper with the Arndt lab is out today: doi.org/10.1093/nar/... (originally bioRxiv: www.biorxiv.org/content/10.1...). Here we asked the question of how CHD1 localizes to chromatin.
A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes
Abstract. The nucleosome remodeler Chd1 is required for the re-establishment of nucleosome positioning in the wake of transcription elongation by RNA Polym
doi.org
August 28, 2025 at 11:07 PM
Our collaborative paper with the Arndt lab is out today: doi.org/10.1093/nar/... (originally bioRxiv: www.biorxiv.org/content/10.1...). Here we asked the question of how CHD1 localizes to chromatin.
Reposted by Sarah Hainer
if i were a better person i would do a tweetorial on our recent paper - but, hey, read the paper. its right there, waiting for you. #Giantvirus #histones are cool! their #nucleosomes are cool. check it out.! thats the tweetorial.
rdcu.be/exXBX
rdcu.be/exXBX
July 26, 2025 at 7:09 PM
if i were a better person i would do a tweetorial on our recent paper - but, hey, read the paper. its right there, waiting for you. #Giantvirus #histones are cool! their #nucleosomes are cool. check it out.! thats the tweetorial.
rdcu.be/exXBX
rdcu.be/exXBX
Reposted by Sarah Hainer
Tenure track position alert! Assistant Professor of Molecular Therapeutics in MCB @UCBerkeley. Apply and come be our colleague! 🎉
aprecruit.berkeley.edu/JPF05098
aprecruit.berkeley.edu/JPF05098
August 21, 2025 at 4:00 AM
Tenure track position alert! Assistant Professor of Molecular Therapeutics in MCB @UCBerkeley. Apply and come be our colleague! 🎉
aprecruit.berkeley.edu/JPF05098
aprecruit.berkeley.edu/JPF05098
Reposted by Sarah Hainer
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
August 20, 2025 at 7:41 PM
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
Reposted by Sarah Hainer
The successful candidate will oversee the management and direction of the OSU Herbarium and establish an independent research program by conducting original research in an area of plant systematics, ecology, and/or evolution.
Assistant/Associate/Full Professor (Botany & Plant Pathology)
The Department of Botany and Plant Pathology invites applications for a full-time (1.00 FTE), 9-month, tenure-track or tenured Assistant, Associate, or Full Professor position.Any hiring at the rank o...
jobs.oregonstate.edu
August 6, 2025 at 4:58 PM
The successful candidate will oversee the management and direction of the OSU Herbarium and establish an independent research program by conducting original research in an area of plant systematics, ecology, and/or evolution.
Reposted by Sarah Hainer
We built a team to represent a coalition of unions, non-profits, & local governments in the largest lawsuit challenging Trump’s authority to remake the government without congressional approval.
Trump's efforts to dismantle the federal government are unconstitutional and we will see him in court.
Trump's efforts to dismantle the federal government are unconstitutional and we will see him in court.
April 29, 2025 at 1:03 AM
We built a team to represent a coalition of unions, non-profits, & local governments in the largest lawsuit challenging Trump’s authority to remake the government without congressional approval.
Trump's efforts to dismantle the federal government are unconstitutional and we will see him in court.
Trump's efforts to dismantle the federal government are unconstitutional and we will see him in court.
Reposted by Sarah Hainer
Interested in synthetic approaches to both understand and manipulate gene expression? We (the Bintu lab) wrote a review that discusses just that - how modern low- and high-throughput approaches can dissect gene regulation at the DNA, RNA, and protein level. www.annualreviews.org/content/jour...
April 28, 2025 at 5:24 PM
Interested in synthetic approaches to both understand and manipulate gene expression? We (the Bintu lab) wrote a review that discusses just that - how modern low- and high-throughput approaches can dissect gene regulation at the DNA, RNA, and protein level. www.annualreviews.org/content/jour...
Reposted by Sarah Hainer
ATTENTION: NSF GRANT RECIPIENTS
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
a cartoon of a man holding a frying pan and a spoon with red alert written above him
ALT: a cartoon of a man holding a frying pan and a spoon with red alert written above him
media.tenor.com
April 24, 2025 at 9:09 PM
ATTENTION: NSF GRANT RECIPIENTS
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
Reposted by Sarah Hainer
Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag
Nadiya Khyzha ∙ Kami Ahmad∙ Steven Henikoff
www.cell.com/molecular-ce...
Nadiya Khyzha ∙ Kami Ahmad∙ Steven Henikoff
www.cell.com/molecular-ce...
Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag
Khyzha et al. developed SLAM-RT&Tag, a kinetic labeling strategy for profiling RNA
dynamics within nuclear compartments. Applied to Polycomb domains and nuclear speckles,
they identified compartment-s...
www.cell.com
March 13, 2025 at 7:09 AM
Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag
Nadiya Khyzha ∙ Kami Ahmad∙ Steven Henikoff
www.cell.com/molecular-ce...
Nadiya Khyzha ∙ Kami Ahmad∙ Steven Henikoff
www.cell.com/molecular-ce...
Reposted by Sarah Hainer
Join us at the 2025 Epigenetics Society International Conference in Chicago! Discover the latest in DNA, RNA, and chromatin epigenetics, steps from Navy Pier & Michigan Ave! www.esconference25.com. #Epigenetics2025 #DNA #RNA #Chromatin #ScientificConference #Chicago
March 12, 2025 at 2:37 PM
Join us at the 2025 Epigenetics Society International Conference in Chicago! Discover the latest in DNA, RNA, and chromatin epigenetics, steps from Navy Pier & Michigan Ave! www.esconference25.com. #Epigenetics2025 #DNA #RNA #Chromatin #ScientificConference #Chicago
Reposted by Sarah Hainer
New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.
That's not to mention the countless lives that biomedical research has saved.
Show me a better investment than that.
www.forbes.com/sites/michae...
That's not to mention the countless lives that biomedical research has saved.
Show me a better investment than that.
www.forbes.com/sites/michae...
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
www.forbes.com
March 12, 2025 at 8:47 PM
New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.
That's not to mention the countless lives that biomedical research has saved.
Show me a better investment than that.
www.forbes.com/sites/michae...
That's not to mention the countless lives that biomedical research has saved.
Show me a better investment than that.
www.forbes.com/sites/michae...
Reposted by Sarah Hainer
Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n
Homepage - openRxiv
openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.
openrxiv.org
March 11, 2025 at 1:20 PM
Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n
Reposted by Sarah Hainer
First @fnucleosome.bsky.social talks of the year coming up on Wednesday! Register to join us
And, if you're interested in presenting with us this year, you can fill out this survey: docs.google.com/forms/d/e/1F...
And, if you're interested in presenting with us this year, you can fill out this survey: docs.google.com/forms/d/e/1F...
January 26, 2025 at 1:18 AM
First @fnucleosome.bsky.social talks of the year coming up on Wednesday! Register to join us
And, if you're interested in presenting with us this year, you can fill out this survey: docs.google.com/forms/d/e/1F...
And, if you're interested in presenting with us this year, you can fill out this survey: docs.google.com/forms/d/e/1F...
Reposted by Sarah Hainer
In case you missed them, a number of our @fnucleosome.bsky.social talks from 2024 are now up on our youtube channel!
Check out the recently uploaded seminars below:
Julia Rogers: Notch induces transcription by stimulating release of paused RNA Pol II
www.youtube.com/watch?v=GME2...
Check out the recently uploaded seminars below:
Julia Rogers: Notch induces transcription by stimulating release of paused RNA Pol II
www.youtube.com/watch?v=GME2...
Julia Rogers
YouTube video by Fragile Nucleosome
www.youtube.com
January 27, 2025 at 12:19 PM
In case you missed them, a number of our @fnucleosome.bsky.social talks from 2024 are now up on our youtube channel!
Check out the recently uploaded seminars below:
Julia Rogers: Notch induces transcription by stimulating release of paused RNA Pol II
www.youtube.com/watch?v=GME2...
Check out the recently uploaded seminars below:
Julia Rogers: Notch induces transcription by stimulating release of paused RNA Pol II
www.youtube.com/watch?v=GME2...
Reposted by Sarah Hainer
PhD studentship!
Chromatin! Structural Biology! Signaling! Stem Cells! Beautiful Devon!
Honestly, what more could you want?
APPLY NOW!
Deadline Friday 10 Jan!
@lsiexeter.bsky.social
Chromatin! Structural Biology! Signaling! Stem Cells! Beautiful Devon!
Honestly, what more could you want?
APPLY NOW!
Deadline Friday 10 Jan!
@lsiexeter.bsky.social
Fully funded #PhD Studentship with myself and JJ Phillips at the Living Systems Institute, @uniofexeter.bsky.social
"Control of chromatin remodeller activity to direct cell fate decisions"
#Chromatin #Transcription #StemCells #StructuralBiology
Please re-skeet!
www.exeter.ac.uk/research/ins...
"Control of chromatin remodeller activity to direct cell fate decisions"
#Chromatin #Transcription #StemCells #StructuralBiology
Please re-skeet!
www.exeter.ac.uk/research/ins...
LSI PhD programme | Living Systems Institute | University of Exeter
www.exeter.ac.uk
January 9, 2025 at 6:59 AM
PhD studentship!
Chromatin! Structural Biology! Signaling! Stem Cells! Beautiful Devon!
Honestly, what more could you want?
APPLY NOW!
Deadline Friday 10 Jan!
@lsiexeter.bsky.social
Chromatin! Structural Biology! Signaling! Stem Cells! Beautiful Devon!
Honestly, what more could you want?
APPLY NOW!
Deadline Friday 10 Jan!
@lsiexeter.bsky.social
Happy New Year from us to you!
January 1, 2025 at 3:22 AM
Happy New Year from us to you!
Happy to share the latest preprint which is a close collaboration with Karen Arndt with a shared PhD student, Sarah Tripplehorn. Here we show a direct interaction between Chd1 and Paf1C subunit Rtf1 required for nucleosome positioning across genes: t.co/E9FSj2nHv8
December 10, 2024 at 12:19 AM
Happy to share the latest preprint which is a close collaboration with Karen Arndt with a shared PhD student, Sarah Tripplehorn. Here we show a direct interaction between Chd1 and Paf1C subunit Rtf1 required for nucleosome positioning across genes: t.co/E9FSj2nHv8
Happy to share work with my close colleague Karen Arndt through a joint PhD student. Here we explored how Chd1 localizes across gene bodies, following up from previous Arndt lab studies identifying Rtf1 as require for Chd1 localization.
A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes https://www.biorxiv.org/content/10.1101/2024.12.06.627179v1
December 7, 2024 at 3:57 AM
Happy to share work with my close colleague Karen Arndt through a joint PhD student. Here we explored how Chd1 localizes across gene bodies, following up from previous Arndt lab studies identifying Rtf1 as require for Chd1 localization.
What an amazing time! Students at #ABRCMS2024 were so impressive! Incredibly proud of all the Pitt Biosci undergrads and grad students
November 18, 2024 at 2:02 AM
What an amazing time! Students at #ABRCMS2024 were so impressive! Incredibly proud of all the Pitt Biosci undergrads and grad students
I could not be more proud of these two amazing women: I told you to watch out for Kya Foxx last year: here she goes giving a talk and winning! And then introducing Bryona Jackson who you should be on the lookout for; just won a poster presentation award. #ABRCMS2024
November 17, 2024 at 3:18 AM
I could not be more proud of these two amazing women: I told you to watch out for Kya Foxx last year: here she goes giving a talk and winning! And then introducing Bryona Jackson who you should be on the lookout for; just won a poster presentation award. #ABRCMS2024
Pitt BIOSC undergrads at #ABRCMS2024
November 15, 2024 at 12:27 AM
Pitt BIOSC undergrads at #ABRCMS2024