Chris Damman, MD 🍓
@gutbitesmd.bsky.social
Gastroenterologist | UW Professor | Gates Foundation Alumnus | CMO & CSO | Scientific Advisory Board | Nutrition, Mitochondria & Gut Microbiome | gutbites.org
Timely article from Alice Callahan @NYT. #guthealth #nutrition #microbiome #ultraprocessedfood www.nytimes.com/2025/11/24/w...
How Do Ultraprocessed Foods Affect the Gut?
www.nytimes.com
November 24, 2025 at 6:28 PM
Timely article from Alice Callahan @NYT. #guthealth #nutrition #microbiome #ultraprocessedfood www.nytimes.com/2025/11/24/w...
Reposted by Chris Damman, MD 🍓
Relying on ChatGPT to teach you about a topic leaves you with shallower knowledge than Googling and reading about it, according to new research that compared what more than 10,000 people knew after using one method or the other.
Shared by @gizmodo.com: buff.ly/yAAHtHq
Shared by @gizmodo.com: buff.ly/yAAHtHq
November 21, 2025 at 11:48 AM
Relying on ChatGPT to teach you about a topic leaves you with shallower knowledge than Googling and reading about it, according to new research that compared what more than 10,000 people knew after using one method or the other.
Shared by @gizmodo.com: buff.ly/yAAHtHq
Shared by @gizmodo.com: buff.ly/yAAHtHq
Research on GLP-1's that target "food noise" in the brain without the GI side effects? www.npr.org/sections/sho...
Brain scientists are seeking weight-loss drugs without the nausea
Weight-loss drugs like Wegovy and Zepbound often cause nausea and other side effects. Brain scientists are looking for ways to solve this problem.
www.npr.org
November 21, 2025 at 2:05 PM
Research on GLP-1's that target "food noise" in the brain without the GI side effects? www.npr.org/sections/sho...
Reposted by Chris Damman, MD 🍓
Editorial about the ultraprocessed food oligopoly putting profit before health www.thelancet.com/journals/lan...
November 19, 2025 at 2:56 PM
Editorial about the ultraprocessed food oligopoly putting profit before health www.thelancet.com/journals/lan...
Reposted by Chris Damman, MD 🍓
A new study finds that eating yogurt regularly may reduce the risk of colon cancer.
The findings are in line with prior studies that have linked yogurt intake to a lower risk of #coloncancer, says Dr. Chris Damman, a @uwmedicine.bsky.social gastroenterologist. @gutbitesmd.bsky.social
The findings are in line with prior studies that have linked yogurt intake to a lower risk of #coloncancer, says Dr. Chris Damman, a @uwmedicine.bsky.social gastroenterologist. @gutbitesmd.bsky.social
Eating yogurt regularly may reduce the risk of colon cancer, a study finds
Humans have been eating yogurt for millennia. Ancient texts reference its health-promoting properties. Now a new study finds yogurt may reduce the risk of certain types of colon cancer.
www.npr.org
February 24, 2025 at 8:01 PM
A new study finds that eating yogurt regularly may reduce the risk of colon cancer.
The findings are in line with prior studies that have linked yogurt intake to a lower risk of #coloncancer, says Dr. Chris Damman, a @uwmedicine.bsky.social gastroenterologist. @gutbitesmd.bsky.social
The findings are in line with prior studies that have linked yogurt intake to a lower risk of #coloncancer, says Dr. Chris Damman, a @uwmedicine.bsky.social gastroenterologist. @gutbitesmd.bsky.social
A paper to suggest ketogenic diet may increase butyrate production via Akkermansia.
Ketogenic diet inhibits glioma progression by promoting gut microbiota-derived butyrate production
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Ketogenic diet inhibits glioma progression by promoting gut microbiota-derived butyrate production
The ketogenic diet (KD) is a potential therapeutic strategy for glioma; however, the underlying mechanisms remain unclear. Herein, we first identify t…
www.sciencedirect.com
November 15, 2025 at 5:31 PM
A paper to suggest ketogenic diet may increase butyrate production via Akkermansia.
Great article! And not all processed foods are equal—what’s missing (fiber, polyphenols, healthy fats, micronutrients) is as important as what’s concentrated (sugar, additives, saturated fat, sodium). Food quality can be captured by ratio balances (e.g. carb-to-fiber). gutbites.org/2025/11/12/u...
November 15, 2025 at 4:33 PM
Great article! And not all processed foods are equal—what’s missing (fiber, polyphenols, healthy fats, micronutrients) is as important as what’s concentrated (sugar, additives, saturated fat, sodium). Food quality can be captured by ratio balances (e.g. carb-to-fiber). gutbites.org/2025/11/12/u...
Ultraprocessed food consumption linked to 45% higher risk of early onset (before age 50) precancerous polyps. jamanetwork.com/journals/jam... #ultraprocessedfood #nutrition
Ultraprocessed Food and Early-Onset Colorectal Cancer Precursors Among Women
This study evaluates the association of the consumption of ultraprocessed foods and the risk of early-onset colorectal cancer (<50 years) in participants of the Nurses’ Health Study II.
jamanetwork.com
November 15, 2025 at 3:58 PM
Ultraprocessed food consumption linked to 45% higher risk of early onset (before age 50) precancerous polyps. jamanetwork.com/journals/jam... #ultraprocessedfood #nutrition
A microbiome-derived metabolite of polyphenols called urolithin A (UA), produced from foods like walnuts and pomegranates, has been shown to expand and rejuvenate cancer- and virus-fighting CD8⁺ T cells while also modulating inflammatory cytokines.
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial - Nature Aging
Immune aging fosters multimorbidity and compromises control of infection and cancer. In a phase 1 randomized controlled trial in middle-aged adults, Denk and colleagues administer the mitophagy induce...
www.nature.com
November 3, 2025 at 2:01 PM
A microbiome-derived metabolite of polyphenols called urolithin A (UA), produced from foods like walnuts and pomegranates, has been shown to expand and rejuvenate cancer- and virus-fighting CD8⁺ T cells while also modulating inflammatory cytokines.
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Developed by a physician and parent, SmartBites is a best-in-class food rating app—powered by cutting-edge nutrition & microbiome science—that simply scans products, suggests smarter versions, and shows how foods combine to better fuel your energy and health.
gutbites.org/2025/09/10/f...
gutbites.org/2025/09/10/f...
A Smarter Way to Shop, Eat & Cook — SmartBites by GutBites MD - Gut Bites MD
Developed by a physician and parent, SmartBites is a best-in-class food rating app that gives you and your family options to eat smarter on the go, without giving up the foods you love. Powered by cut...
gutbites.org
September 10, 2025 at 1:44 PM
Developed by a physician and parent, SmartBites is a best-in-class food rating app—powered by cutting-edge nutrition & microbiome science—that simply scans products, suggests smarter versions, and shows how foods combine to better fuel your energy and health.
gutbites.org/2025/09/10/f...
gutbites.org/2025/09/10/f...
New randomized cross over study in Nature Medicine showing that minimally processed vs. ultraprocessed foods contribute to significantly greater weight loss and body fat composition change. www.nature.com/articles/s41...
Ultraprocessed or minimally processed diets following healthy dietary guidelines on weight and cardiometabolic health: a randomized, crossover trial - Nature Medicine
A free-living trial in people with overweight or obesity found that minimally processed diets led to greater weight loss and cardiometabolic improvements than ultraprocessed diets following UK healthy...
www.nature.com
August 10, 2025 at 1:16 PM
New randomized cross over study in Nature Medicine showing that minimally processed vs. ultraprocessed foods contribute to significantly greater weight loss and body fat composition change. www.nature.com/articles/s41...
Metformin may work, in part, by stimulating the excretion of glucose into the intestine. www.nature.com/articles/s43...
Metformin-regulated glucose flux from the circulation to the intestinal lumen - Communications Medicine
Sakaguchi, Sugawara, Hosokawa, Ito, Morita, et al. quantify the effect of metformin on intestinal glucose excretion using fluorodeoxyglucose PET-MRI based bioimaging in individuals with type 2 diabete...
www.nature.com
April 23, 2025 at 12:15 PM
Metformin may work, in part, by stimulating the excretion of glucose into the intestine. www.nature.com/articles/s43...
With age, the microbiome becomes less robust, producing a less diverse metabolome that is otherwise key for healthy host functions. www.nature.com/articles/s41...
Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice - Nature Microbiology
A multi-omics approach reveals host–microbiome interactions in aging in mice.
www.nature.com
April 22, 2025 at 12:41 PM
With age, the microbiome becomes less robust, producing a less diverse metabolome that is otherwise key for healthy host functions. www.nature.com/articles/s41...
The #microbiome metabolites of #fiber, #butyrate, and #propionate play a dual role in colon cancer. They suppress cancer development through epigenetic regulation but can further dysregulate oncogenic pathways in existing cancer cells. Nature Metabolism www.nature.com/articles/s42...
Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression - Nature Metabolism
Nshanian et al. investigate the differential effects of the short-chain fatty acids propionate and butyrate on chromatin remodelling and gain insight into the mechanisms that drive selective histone a...
www.nature.com
January 11, 2025 at 2:40 PM
The #microbiome metabolites of #fiber, #butyrate, and #propionate play a dual role in colon cancer. They suppress cancer development through epigenetic regulation but can further dysregulate oncogenic pathways in existing cancer cells. Nature Metabolism www.nature.com/articles/s42...
Gut microbiome signatures compared across vegan, vegetarian and omnivore diets. withttps://www.nature.com/articles/s41564-024-01870-z
Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals - Nature Microbiology
Using 21,561 individuals, the authors present a cross-sectional study of how gut microbiome signatures are associated with dietary intake patterns and with host health outcomes.
www.nature.com
January 10, 2025 at 2:10 PM
Gut microbiome signatures compared across vegan, vegetarian and omnivore diets. withttps://www.nature.com/articles/s41564-024-01870-z
Eating a wide array of plant-based foods is more important than whether or not you eat meat in determining the composition of a healthy microbiome. www.npr.org/sections/sho...
Hey, meat eaters. Your gut health can rival a vegan's. Here's how
Our guts are home to trillions of microbes that influence our health. A new study finds the key to a healthy microbiome is the variety of plant-based food in your diet, even if you eat meat.
www.npr.org
January 10, 2025 at 2:07 PM
Eating a wide array of plant-based foods is more important than whether or not you eat meat in determining the composition of a healthy microbiome. www.npr.org/sections/sho...
Sharing a public good project I’ve been working on to help guide healthy & balanced eating much like Nutri-Score in Europe and Health Star in Australia. App in beta test and paper in peer review.
gutbites.org/nutrient-con...
gutbites.org/nutrient-con...
NCS App: Your Pocket Guide to Balanced Gut Healthy Eating - Gut Bites MD
Introducing a smart, evidence-based food quality app that helps users make more balanced dietary choices. By analyzing nutrient ratios and microbiome-friendly bioactive factors, it generates a simple ...
gutbites.org
December 26, 2024 at 4:14 PM
Sharing a public good project I’ve been working on to help guide healthy & balanced eating much like Nutri-Score in Europe and Health Star in Australia. App in beta test and paper in peer review.
gutbites.org/nutrient-con...
gutbites.org/nutrient-con...
Urolithin A, a microbiome-derived metabolite of the polyphenol ellagitannin, improves strength and endurance in a randomized controlled trial of resistance-trained athletes.
www.tandfonline.com/doi/full/10....
www.tandfonline.com/doi/full/10....
Assessment of Urolithin A effects on muscle endurance, strength, inflammation, oxidative stress, and protein metabolism in male athletes with resistance training: an 8-week randomized, double-blind, p...
This study aimed to investigate the impact of Urolithin A (UA) on muscle endurance, muscle strength, inflammatory levels, oxidative stress, and protein metabolism status in resistance-trained male ...
www.tandfonline.com
December 10, 2024 at 2:37 PM
Urolithin A, a microbiome-derived metabolite of the polyphenol ellagitannin, improves strength and endurance in a randomized controlled trial of resistance-trained athletes.
www.tandfonline.com/doi/full/10....
www.tandfonline.com/doi/full/10....
Beyond mitochondria, endosymbionts discovered to exists in other realms of nature.
Paper: www.nature.com/articles/s41...
Editorial: phys.org/news/2024-12...
Paper: www.nature.com/articles/s41...
Editorial: phys.org/news/2024-12...
Genetic potential for aerobic respiration and denitrification in globally distributed respiratory endosymbionts - Nature Communications
In this study, the authors report and analyze four complete genomes of respiratory endosymbionts to show that they carry the potential to breathe both oxygen and nitrogen oxides providing energy to th...
www.nature.com
December 10, 2024 at 2:26 PM
Beyond mitochondria, endosymbionts discovered to exists in other realms of nature.
Paper: www.nature.com/articles/s41...
Editorial: phys.org/news/2024-12...
Paper: www.nature.com/articles/s41...
Editorial: phys.org/news/2024-12...
Polyphenols effect gut microbiome and inflammatory markers in overweight and obesity. www.tandfonline.com/doi/abs/10.1...
Effects of polyphenols on gut microbiota and inflammatory markers in individuals with overweight or obesity: a systematic review and meta-analysis of randomized controlled trials
Polyphenols are potent antioxidants with anti-microbial, anti-inflammatory, and prebiotic effects. However, no meta-analysis of human studies has confirmed these properties in individuals with over...
www.tandfonline.com
December 7, 2024 at 7:08 PM
Polyphenols effect gut microbiome and inflammatory markers in overweight and obesity. www.tandfonline.com/doi/abs/10.1...