Kushol Gupta
@guptapenn.bsky.social
Research Assistant Professor of Biochemistry and Biophysics | Director, Johnson Foundation Biophysics and Structural Biology Core Facility | Univ of PA | he/him
Reposted by Kushol Gupta
Using X-rays at CHESS, Dr. Kushol Gupta (@guptapenn.bsky.social) and UPenn Medicine scientists found that DNA’s building blocks can unfold under high pressure and spring back when pressure eases, offering new clues into genome stability and disease.
Read more: bit.ly/48TkDbo
Read more: bit.ly/48TkDbo
October 29, 2025 at 5:07 PM
Using X-rays at CHESS, Dr. Kushol Gupta (@guptapenn.bsky.social) and UPenn Medicine scientists found that DNA’s building blocks can unfold under high pressure and spring back when pressure eases, offering new clues into genome stability and disease.
Read more: bit.ly/48TkDbo
Read more: bit.ly/48TkDbo
Reposted by Kushol Gupta
We dusted off a nearly 100-year-old vinyl record from The University of Pennsylvania Band and gave “The Red and Blue” another spin. The sound may crackle a little, but the Penn pride still comes through loud and clear ❤️💙
October 23, 2025 at 7:04 PM
We dusted off a nearly 100-year-old vinyl record from The University of Pennsylvania Band and gave “The Red and Blue” another spin. The sound may crackle a little, but the Penn pride still comes through loud and clear ❤️💙
Reposted by Kushol Gupta
Elucidating lipid nanoparticle properties and structure through biophysical analyses - @guptapenn.bsky.social
@pennengineering.bsky.social @pennmedicine.bsky.social go.nature.com/4oTt639
@pennengineering.bsky.social @pennmedicine.bsky.social go.nature.com/4oTt639
Elucidating lipid nanoparticle properties and structure through biophysical analyses - Nature Biotechnology
Guidance for optimizing lipid nanoparticle formulations is derived using sophisticated biophysical techniques.
go.nature.com
October 23, 2025 at 4:24 PM
Elucidating lipid nanoparticle properties and structure through biophysical analyses - @guptapenn.bsky.social
@pennengineering.bsky.social @pennmedicine.bsky.social go.nature.com/4oTt639
@pennengineering.bsky.social @pennmedicine.bsky.social go.nature.com/4oTt639
I'm really grateful for this write-up from @chess-synchrotron.bsky.social (CHESS) on the high-pressure SAXS work that was featured in our recent collaborative work!
www.chess.cornell.edu/under-pressu...
www.chess.cornell.edu/under-pressu...
Under Pressure: How CHESS Helped Reveal Hidden Differences in Our DNA Packaging | CHESS
www.chess.cornell.edu
October 17, 2025 at 2:29 PM
I'm really grateful for this write-up from @chess-synchrotron.bsky.social (CHESS) on the high-pressure SAXS work that was featured in our recent collaborative work!
www.chess.cornell.edu/under-pressu...
www.chess.cornell.edu/under-pressu...
Reposted by Kushol Gupta
Great to see this article by @guptapenn.bsky.social is out! Kushol helped us interview @xtalmaker.bsky.social Vivian Stojanoff and @gabbygrowsxtals.bsky.social who published an article on careful sample preparation in crystallisation experiments, also part of #SAMPREP
www.youtube.com/watch?v=m34R...
www.youtube.com/watch?v=m34R...
October 10, 2025 at 10:07 AM
Great to see this article by @guptapenn.bsky.social is out! Kushol helped us interview @xtalmaker.bsky.social Vivian Stojanoff and @gabbygrowsxtals.bsky.social who published an article on careful sample preparation in crystallisation experiments, also part of #SAMPREP
www.youtube.com/watch?v=m34R...
www.youtube.com/watch?v=m34R...
It was alot of fun to help with this interview of the authors!!
As the community gets ready for #ACA2025, we're proud to present this interview with @gabbygrowsxtals.bsky.social Vivian Stojanoff and @xtalmaker.bsky.social on how to prepare for successful protein crystallisation experiments! 🥳🥳 youtu.be/m34RI500OFU?...
Preparing for successful protein crystallization experiments
YouTube video by International Union of Crystallography
youtu.be
July 14, 2025 at 2:22 PM
It was alot of fun to help with this interview of the authors!!
Reposted by Kushol Gupta
Breaking news: Staff at the National Institutes of Health have issued a declaration calling on their director to depoliticize the agency and reverse spending cuts.
NIH staff and biomedical community sound alarm about agency politicization, funding slowdown
In test of NIH director’s support of dissent, NIH staff sign Bethesda Declaration urging reversal of grant cuts and freezes
scim.ag
June 9, 2025 at 12:13 PM
Breaking news: Staff at the National Institutes of Health have issued a declaration calling on their director to depoliticize the agency and reverse spending cuts.
A lot of celebrating in the lab this week!
Undergraduates Nancy An (Masters in Biochem, headed to Stanford Law) and Jacob Issacs are graduating (BA in Biochem, headed to RPI for PhD studies), along with Bioengineering Master's student Liam Rivard!
Undergraduates Nancy An (Masters in Biochem, headed to Stanford Law) and Jacob Issacs are graduating (BA in Biochem, headed to RPI for PhD studies), along with Bioengineering Master's student Liam Rivard!
May 18, 2025 at 5:25 PM
A lot of celebrating in the lab this week!
Undergraduates Nancy An (Masters in Biochem, headed to Stanford Law) and Jacob Issacs are graduating (BA in Biochem, headed to RPI for PhD studies), along with Bioengineering Master's student Liam Rivard!
Undergraduates Nancy An (Masters in Biochem, headed to Stanford Law) and Jacob Issacs are graduating (BA in Biochem, headed to RPI for PhD studies), along with Bioengineering Master's student Liam Rivard!
Reposted by Kushol Gupta
After Trump’s first 100 days, agency scientists say U.S. health institutes are demoralized and have lost essential staff and funding.
NIH insiders: Trump is ‘dismantling and destroying everything'
After just 100 days, agency scientists say U.S. health institutes are demoralized and have lost essential staff and funding
scim.ag
April 30, 2025 at 9:56 PM
After Trump’s first 100 days, agency scientists say U.S. health institutes are demoralized and have lost essential staff and funding.
Registration is still open, but only a small number of spots are left!
www.med.upenn.edu/jf/aucsymp.h...
@BB_UPenn
@pennmedicine.bsky.social
www.med.upenn.edu/jf/aucsymp.h...
@BB_UPenn
@pennmedicine.bsky.social
April 17, 2025 at 3:38 PM
Registration is still open, but only a small number of spots are left!
www.med.upenn.edu/jf/aucsymp.h...
@BB_UPenn
@pennmedicine.bsky.social
www.med.upenn.edu/jf/aucsymp.h...
@BB_UPenn
@pennmedicine.bsky.social
Reposted by Kushol Gupta
For those of you attending the 2025 American Crystallographic Association meeting in Lombard, IL in July: consider this workshop Dr. Maxwell Watkins (APS BioCAT) and I are organizing for the community, and don't forget to register!
#structure #lightscattering #AUC
#structure #lightscattering #AUC
March 6, 2025 at 10:45 PM
For those of you attending the 2025 American Crystallographic Association meeting in Lombard, IL in July: consider this workshop Dr. Maxwell Watkins (APS BioCAT) and I are organizing for the community, and don't forget to register!
#structure #lightscattering #AUC
#structure #lightscattering #AUC
Reposted by Kushol Gupta
Working with an interdisciplinary team, we have developed a website to communicate how the White House's proposed cuts to health research would cause losses of $16B and 68,500 jobs.
Find out how your community may be impacted.
Explore more at SCIMaP: scienceimpacts.org
a 🧵
Find out how your community may be impacted.
Explore more at SCIMaP: scienceimpacts.org
a 🧵
March 28, 2025 at 2:15 AM
Working with an interdisciplinary team, we have developed a website to communicate how the White House's proposed cuts to health research would cause losses of $16B and 68,500 jobs.
Find out how your community may be impacted.
Explore more at SCIMaP: scienceimpacts.org
a 🧵
Find out how your community may be impacted.
Explore more at SCIMaP: scienceimpacts.org
a 🧵
Championing Science: ACA’s Commitment to Research, Collaboration, and Advocacy
acas.memberclicks.net/index.php?op...
acas.memberclicks.net/index.php?op...
Championing Science: ACA’s Commitment to Research, Collaboration, and Advocacy
acas.memberclicks.net
March 19, 2025 at 7:13 PM
Championing Science: ACA’s Commitment to Research, Collaboration, and Advocacy
acas.memberclicks.net/index.php?op...
acas.memberclicks.net/index.php?op...
A great crowd here in Philadelphia at the @standupforscience.bsky.social rally! #standupforscience
March 8, 2025 at 1:32 PM
A great crowd here in Philadelphia at the @standupforscience.bsky.social rally! #standupforscience
For those of you attending the 2025 American Crystallographic Association meeting in Lombard, IL in July: consider this workshop Dr. Maxwell Watkins (APS BioCAT) and I are organizing for the community, and don't forget to register!
#structure #lightscattering #AUC
#structure #lightscattering #AUC
March 6, 2025 at 10:45 PM
For those of you attending the 2025 American Crystallographic Association meeting in Lombard, IL in July: consider this workshop Dr. Maxwell Watkins (APS BioCAT) and I are organizing for the community, and don't forget to register!
#structure #lightscattering #AUC
#structure #lightscattering #AUC
Registration is open! - in addition to our traditional session on modern applications of AUC, we'll also be holding a special afternoon session on emerging biophysical methods as applied to therapeutic nanoparticles!
www.med.upenn.edu/jf/aucsymp.h...
@BB_UPenn @pennmedicine.bsky.social
www.med.upenn.edu/jf/aucsymp.h...
@BB_UPenn @pennmedicine.bsky.social
March 5, 2025 at 2:08 PM
Registration is open! - in addition to our traditional session on modern applications of AUC, we'll also be holding a special afternoon session on emerging biophysical methods as applied to therapeutic nanoparticles!
www.med.upenn.edu/jf/aucsymp.h...
@BB_UPenn @pennmedicine.bsky.social
www.med.upenn.edu/jf/aucsymp.h...
@BB_UPenn @pennmedicine.bsky.social
Safeguarding the future of biomedical science in the United States: Cell www.cell.com/cell/fulltex...
Safeguarding the future of biomedical science in the United States
NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical
infrastructure supporting groundbreaking biomedical research in the United States.
This policy jeopardizes Americ...
www.cell.com
March 2, 2025 at 4:06 PM
Safeguarding the future of biomedical science in the United States: Cell www.cell.com/cell/fulltex...
Reposted by Kushol Gupta
PLOS has issued a statement on recent US Executive Orders and scientific integrity.
We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog
Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…
plos.io
February 21, 2025 at 3:41 PM
PLOS has issued a statement on recent US Executive Orders and scientific integrity.
We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.
plos.io/3D4O8cH
Ax falls on elite group of Ph.D.s training to lead U.S. public health labs | Science | AAAS www.science.org/content/arti...
Ax falls on elite group of Ph.D.s training to lead U.S. public health labs
Most of the fellows in CDC’s highly competitive Laboratory Leadership Service were fired last weekend
www.science.org
February 21, 2025 at 12:22 PM
Ax falls on elite group of Ph.D.s training to lead U.S. public health labs | Science | AAAS www.science.org/content/arti...
There's never been a better time to celebrate young scientists.
Lab Happy Hour Yesterday:
Lab Happy Hour Yesterday:
February 20, 2025 at 6:47 PM
There's never been a better time to celebrate young scientists.
Lab Happy Hour Yesterday:
Lab Happy Hour Yesterday:
Want to do something concrete? help them out.
‘I really wanted something to happen.’ The students behind the Stand Up for Science protests | Science | AAAS www.science.org/content/arti...
‘I really wanted something to happen.’ The students behind the Stand Up for Science protests | Science | AAAS www.science.org/content/arti...
‘I really wanted something to happen.’ The students behind the Stand Up for Science protests
New group hopes to turn out researchers for 7 March demonstrations against Trump administration policies
www.science.org
February 19, 2025 at 2:18 AM
Want to do something concrete? help them out.
‘I really wanted something to happen.’ The students behind the Stand Up for Science protests | Science | AAAS www.science.org/content/arti...
‘I really wanted something to happen.’ The students behind the Stand Up for Science protests | Science | AAAS www.science.org/content/arti...
Reposted by Kushol Gupta
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
February 12, 2025 at 5:04 PM
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Reposted by Kushol Gupta
February 7, 2025 at 9:54 AM
Reposted by Kushol Gupta
Dear US elected officials:
"Science is hard enough, don't make it even harder! Work to remove restrictions on scientists immediately. Any delay will have deep, immediate, and long-lasting detrimental economic consequences."
You can send your message here:
www.biophysics.org/policy-advoc...
"Science is hard enough, don't make it even harder! Work to remove restrictions on scientists immediately. Any delay will have deep, immediate, and long-lasting detrimental economic consequences."
You can send your message here:
www.biophysics.org/policy-advoc...
Policy & Advocacy - Take Action | The Biophysical Society
www.biophysics.org
January 27, 2025 at 8:43 PM
Dear US elected officials:
"Science is hard enough, don't make it even harder! Work to remove restrictions on scientists immediately. Any delay will have deep, immediate, and long-lasting detrimental economic consequences."
You can send your message here:
www.biophysics.org/policy-advoc...
"Science is hard enough, don't make it even harder! Work to remove restrictions on scientists immediately. Any delay will have deep, immediate, and long-lasting detrimental economic consequences."
You can send your message here:
www.biophysics.org/policy-advoc...