Lara K. Mahal
@glycocode.bsky.social
CERC in Glycomics, Director of Glycomics Institute of Alberta(www.glyco-alberta.ca), Professor of Chemistry, Univ. of Alberta. Work on #glycotime with lectin microarrays and discovering new aspects of #miRNA. Opinions are mine (she/her). www.glycocode.org
Pinned
Lara K. Mahal
@glycocode.bsky.social
· Jan 13
Screening the human miRNA interactome reveals coordinated up-regulation in melanoma, adding bidirectional regulation to miRNA networks
Analysis of ST3GAL1/2 and CD98hc regulation by miRNA reveals co–up-regulation, adding a bidirectional twist to miRNA networks.
www.science.org
Proud of @faezehjame.bsky.social and our latest paper on upregulation by #miRNA. miRNA upregulate protein expression of CD98hc, ST3GAL1 and ST3GAL2 in a coordinated manner. Regulation is bidirectional, changing the picture on how these #RNA work. #glycotime
www.science.org/doi/10.1126/... 🧪
www.science.org/doi/10.1126/... 🧪
Reposted by Lara K. Mahal
Come hear a Nobel Laureate talk about her cutting edge research! Free and open to all.
Neighbors! Get the scoop on what your local Nobel laureate is working on now to reveal the roots of cancer and other diseases. Our NEW "Science in the Neighborhood" public lecture series kicks off w/ UCSC's Carol Greider!
Sign up now. It's free and starts at 6pm on Dec. 11 at our coastal campus 🌊
Sign up now. It's free and starts at 6pm on Dec. 11 at our coastal campus 🌊
November 21, 2025 at 8:52 PM
Come hear a Nobel Laureate talk about her cutting edge research! Free and open to all.
Delighted to share our new pre-print from PhD student Ziyun Zhang joint with @tracyh9494.bsky.social demonstrating that lung alveolar macrophages have a dense glycocalyx and interstitial macrophages do not, @mcrcellmatrix.bsky.social @lydiabeckeriii.bsky.social www.biorxiv.org/content/10.1...
Airway macrophage specific expression of a dense glycocalyx and its remodelling following viral infection
The glycocalyx is best studied for its regulation of immune cell trafficking from the vasculature into inflamed tissues. The glycocalyx is composed of a range of glycans and glyco-proteins that form a...
www.biorxiv.org
November 22, 2025 at 8:53 PM
Reposted by Lara K. Mahal
I need everyone, esp anyone working in education or tech (but really everyone) to WATCH THIS CLIP of @drtanksley.bsky.social discussing the technologies infiltrating our schools & psyches and how she is addressing it with our young people. youtu.be/5mtcSL4S3HQ
Howard University AI Panel
YouTube video by Tiera Tanksley
youtu.be
November 22, 2025 at 1:43 PM
I need everyone, esp anyone working in education or tech (but really everyone) to WATCH THIS CLIP of @drtanksley.bsky.social discussing the technologies infiltrating our schools & psyches and how she is addressing it with our young people. youtu.be/5mtcSL4S3HQ
Reposted by Lara K. Mahal
It's Friday, and apparently bluesky is ready for this fun revelation:
Dinosaurs lived on the other side the Galaxy.
Dinosaurs lived on the other side the Galaxy.
November 21, 2025 at 5:11 PM
It's Friday, and apparently bluesky is ready for this fun revelation:
Dinosaurs lived on the other side the Galaxy.
Dinosaurs lived on the other side the Galaxy.
Reposted by Lara K. Mahal
November 21, 2025 at 6:14 PM
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Calling all rising juniors & seniors: Interested in biological or biomedical research? Applications for our ’26 Summer Undergraduate Research Experience Program are now open! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellows
Summer Undergraduate Research Experience | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
bit.ly
November 21, 2025 at 8:03 PM
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Reposted by Lara K. Mahal
I was just thinking about this again yesterday
What if We Can’t Rely on PubMed? absolutelymaybe.plos.org/2025/02/14/w...
What if We Can’t Rely on PubMed? absolutelymaybe.plos.org/2025/02/14/w...
What if We Can't Rely on PubMed? - Absolutely Maybe
PubMed is incredibly reliable. And a lot depends on it. It’s an ecosystem built around MEDLINE, the steady feed of new publications…
absolutelymaybe.plos.org
November 20, 2025 at 1:28 PM
I was just thinking about this again yesterday
What if We Can’t Rely on PubMed? absolutelymaybe.plos.org/2025/02/14/w...
What if We Can’t Rely on PubMed? absolutelymaybe.plos.org/2025/02/14/w...
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We’re hiring a Research Assistant!
Join the Brain Resilience Study team and support a major INN project on brain health and aging. If you're passionate about collaborative team science and multimodal data collection, submit your application to [email protected] by Nov 28th. Learn more: shorturl.at/QMFV0
Join the Brain Resilience Study team and support a major INN project on brain health and aging. If you're passionate about collaborative team science and multimodal data collection, submit your application to [email protected] by Nov 28th. Learn more: shorturl.at/QMFV0
November 20, 2025 at 2:50 AM
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Reposted by Lara K. Mahal
In a new phase 3 trial, people randomly assigned to receive a flu shot made with modified mRNA were 34.5% less likely to be diagnosed with an influenza-like illness than people given a standard flu shot made with inactivated virus.
We need to stop the anti-science attacks against mRNA vaccines!
We need to stop the anti-science attacks against mRNA vaccines!
November 20, 2025 at 1:03 AM
In a new phase 3 trial, people randomly assigned to receive a flu shot made with modified mRNA were 34.5% less likely to be diagnosed with an influenza-like illness than people given a standard flu shot made with inactivated virus.
We need to stop the anti-science attacks against mRNA vaccines!
We need to stop the anti-science attacks against mRNA vaccines!
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Such a wonderful and unique meeting. Small scale, very interactive, amazing speakers and participants and all on the remarkable UCSC campus,. HIGHLY recommended!!!
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
November 20, 2025 at 1:37 AM
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Reposted by Lara K. Mahal
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
November 19, 2025 at 8:23 PM
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
Reposted by Lara K. Mahal
If you need me, I'll be crying in the walken freezer.
February 11, 2025 at 2:33 AM
If you need me, I'll be crying in the walken freezer.
Reposted by Lara K. Mahal
Not only were the chatbots unreliable at correctly identifying retracted papers, they spit out different results when given the same prompts.
AI unreliable in identifying retracted research papers, says study
LLMs don’t reliably identify retracted papers, a new study finds. (Image: DALL-E) Large language models should not be used to weed out retracted literature, a study of 21 chatbots concludes. …
retractionwatch.com
November 19, 2025 at 6:03 PM
Not only were the chatbots unreliable at correctly identifying retracted papers, they spit out different results when given the same prompts.
Reposted by Lara K. Mahal
Hi, it's me again
I have these calendars. They are so pretty. @megstampede.bsky.social made them. They have a bunch of animals on them, like crows and humpbacks and cuttlefish and salamanders.
Each month has facts about the animals AND actions you can take to help them
Get one at Squidfacts.net!
I have these calendars. They are so pretty. @megstampede.bsky.social made them. They have a bunch of animals on them, like crows and humpbacks and cuttlefish and salamanders.
Each month has facts about the animals AND actions you can take to help them
Get one at Squidfacts.net!
November 18, 2025 at 7:16 PM
Hi, it's me again
I have these calendars. They are so pretty. @megstampede.bsky.social made them. They have a bunch of animals on them, like crows and humpbacks and cuttlefish and salamanders.
Each month has facts about the animals AND actions you can take to help them
Get one at Squidfacts.net!
I have these calendars. They are so pretty. @megstampede.bsky.social made them. They have a bunch of animals on them, like crows and humpbacks and cuttlefish and salamanders.
Each month has facts about the animals AND actions you can take to help them
Get one at Squidfacts.net!
🧪🇨🇦
Apply for the 'Dr. Connie Eaves Chair in Cancer Cell Research' at UBC. Come join the dynamic research community in Vancouver 🇨🇦!
Associate Professor (tenure) or Professor (tenure) Dr. Connie Eaves Chair in Cancer Stem Cell Research
Academic Job Category Faculty Bargaining Job Title Associate Professor (tenure) or Professor (tenure) Dr. Connie Eaves Chair in Cancer Stem Cell Research Department School of Biomedical Engineering | ...
ubc.wd10.myworkdayjobs.com
November 19, 2025 at 1:03 AM
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Reposted by Lara K. Mahal
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
November 18, 2025 at 10:18 AM
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
Reposted by Lara K. Mahal
Excited about Kolya Aleksashin's new work, enabling preparation of active in vitro translation systems from primary human cells and difficult-to-edit cells (fibroblasts and cardiomyocytes). This opens new opportunities to probe mechanisms of translation regulation.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Overcoming the eIF2α Brake in Human Cell-Derived Translation Systems
Cell-free translation from human cells is a powerful platform for studying mammalian gene expression and building synthetic biology tools, but productivity is often curtailed by inhibitory phosphoryla...
www.biorxiv.org
November 18, 2025 at 6:29 PM
Excited about Kolya Aleksashin's new work, enabling preparation of active in vitro translation systems from primary human cells and difficult-to-edit cells (fibroblasts and cardiomyocytes). This opens new opportunities to probe mechanisms of translation regulation.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Lara K. Mahal
📢 Today we celebrate International Day of LGBTQIA+ People In STEM!
📷 A drop of rainbow” (Lara Barrio): 🔴🟢🔵 With just three fluorescent markers it's possible to generate 7 colour combinations that allow researchers to track multiple cell populations in #Drosophila.
#LGBTQSTEMDay #PrideInSTEM
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📷 A drop of rainbow” (Lara Barrio): 🔴🟢🔵 With just three fluorescent markers it's possible to generate 7 colour combinations that allow researchers to track multiple cell populations in #Drosophila.
#LGBTQSTEMDay #PrideInSTEM
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November 18, 2025 at 10:30 AM
📢 Today we celebrate International Day of LGBTQIA+ People In STEM!
📷 A drop of rainbow” (Lara Barrio): 🔴🟢🔵 With just three fluorescent markers it's possible to generate 7 colour combinations that allow researchers to track multiple cell populations in #Drosophila.
#LGBTQSTEMDay #PrideInSTEM
🧪
📷 A drop of rainbow” (Lara Barrio): 🔴🟢🔵 With just three fluorescent markers it's possible to generate 7 colour combinations that allow researchers to track multiple cell populations in #Drosophila.
#LGBTQSTEMDay #PrideInSTEM
🧪
Reposted by Lara K. Mahal
www.ualberta.ca/en/news/spot...
Here’s another look at our recent publication—this time with a Folio piece into what we found and why it matters. Check out the new post highlighting the key insights from the study.
People can access this data on our labs website: amsrguofa.ca/datasets/
Here’s another look at our recent publication—this time with a Folio piece into what we found and why it matters. Check out the new post highlighting the key insights from the study.
People can access this data on our labs website: amsrguofa.ca/datasets/
Study shows how brain’s immune cells help with recovery from multiple sclerosis
A U of A team has mapped how the brain’s immune cells drive recovery of nerve protection in multiple sclerosis, offering a new target for drug discovery.
www.ualberta.ca
November 18, 2025 at 7:05 PM
www.ualberta.ca/en/news/spot...
Here’s another look at our recent publication—this time with a Folio piece into what we found and why it matters. Check out the new post highlighting the key insights from the study.
People can access this data on our labs website: amsrguofa.ca/datasets/
Here’s another look at our recent publication—this time with a Folio piece into what we found and why it matters. Check out the new post highlighting the key insights from the study.
People can access this data on our labs website: amsrguofa.ca/datasets/
Reposted by Lara K. Mahal
CERN celebrates LGBTQ+ in STEM Day
Today we celebrate and highlight the work of and barriers facing LGBTQIA+ people in science, technology, engineering and maths. To mark the date, the Progress Pride flag will fly above the Esplanade des Particules for the third year.
🔗 home.cern/news/news/ce...
Today we celebrate and highlight the work of and barriers facing LGBTQIA+ people in science, technology, engineering and maths. To mark the date, the Progress Pride flag will fly above the Esplanade des Particules for the third year.
🔗 home.cern/news/news/ce...
November 18, 2025 at 1:51 PM
CERN celebrates LGBTQ+ in STEM Day
Today we celebrate and highlight the work of and barriers facing LGBTQIA+ people in science, technology, engineering and maths. To mark the date, the Progress Pride flag will fly above the Esplanade des Particules for the third year.
🔗 home.cern/news/news/ce...
Today we celebrate and highlight the work of and barriers facing LGBTQIA+ people in science, technology, engineering and maths. To mark the date, the Progress Pride flag will fly above the Esplanade des Particules for the third year.
🔗 home.cern/news/news/ce...
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Less than 2 weeks left to apply!
Join the international, vibrant and drama-free biomedical research community in Toronto.
Join the international, vibrant and drama-free biomedical research community in Toronto.
Launch your independent research career in beautiful Toronto!
Princess Margaret Cancer Centre is recruiting an ECR in cancer biology with appointment to University of Toronto and a generous startup package. Vibrant research community.
Apply now!
www.nature.com/naturecareer...
Princess Margaret Cancer Centre is recruiting an ECR in cancer biology with appointment to University of Toronto and a generous startup package. Vibrant research community.
Apply now!
www.nature.com/naturecareer...
November 18, 2025 at 4:03 PM
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Reposted by Lara K. Mahal
Part 172 of 200 in historically interesting things to inspire your ttrpg dnd
An ancient Roman mosaic depicting a rabbit driving a chariot pulled by geese.
An ancient Roman mosaic depicting a rabbit driving a chariot pulled by geese.
November 18, 2025 at 1:45 AM
Part 172 of 200 in historically interesting things to inspire your ttrpg dnd
An ancient Roman mosaic depicting a rabbit driving a chariot pulled by geese.
An ancient Roman mosaic depicting a rabbit driving a chariot pulled by geese.
Reposted by Lara K. Mahal
Mark your calendars for November 27th from 2:30–3:30 PM PST for a talk from Dr. David Vocadlo for a talk on “Chemical Glycobiology Tools for Discovery and Translation in Neurodegenerative Diseases.”
For more details, visit: www.sfu.ca/neuro-instit...
For more details, visit: www.sfu.ca/neuro-instit...
November 18, 2025 at 1:24 AM
Mark your calendars for November 27th from 2:30–3:30 PM PST for a talk from Dr. David Vocadlo for a talk on “Chemical Glycobiology Tools for Discovery and Translation in Neurodegenerative Diseases.”
For more details, visit: www.sfu.ca/neuro-instit...
For more details, visit: www.sfu.ca/neuro-instit...
Reposted by Lara K. Mahal
Prashant Singh in the lab of Tina Iverson at Vanderbilt published this image of the bacterial 🦠flagellar motor, a detailed molecular model made possibly by CryoEM 🔬.
The similarity to mechanical motors are strong enough we can use terms like stator, rotor, rod & gearing to describe it.
The similarity to mechanical motors are strong enough we can use terms like stator, rotor, rod & gearing to describe it.
November 17, 2025 at 10:31 PM
Prashant Singh in the lab of Tina Iverson at Vanderbilt published this image of the bacterial 🦠flagellar motor, a detailed molecular model made possibly by CryoEM 🔬.
The similarity to mechanical motors are strong enough we can use terms like stator, rotor, rod & gearing to describe it.
The similarity to mechanical motors are strong enough we can use terms like stator, rotor, rod & gearing to describe it.
