Mass General Brigham researchers engineered a virus that destroys brain tumor cells while avoiding healthy brain tissue.

Great things can happen when the right minds come together. The story of Gordon Freeman and Arlene Sharpe is an excellent example of this adage. The two US researchers have been married since 1978 and in the 1980s began exploring one of the biggest questions in medicine: how do our bodies control the immune system, and how can this knowledge be harnessed for therapeutic benefit? The award-winning research conducted by Freeman and Sharpe has gone a long way towards answering these key questions. Yesterday, they received yet another honor for their work, the Gretener-Thürlemann Prize, awarded by the University of

The importance of peripheral immunity in Alzheimer disease has gained much traction in recent years, mainly due to multiple genome-wide association studies identifying risk loci associated with genes ...

Enteric neurons are essential regulators of intestinal physiology, yet their responses to varying microbial and immune environments along the intestinal tract and or during challenges remain poorly un...

Enteric neurons are essential regulators of intestinal physiology, yet their responses to varying microbial and immune environments along the intestinal tract and or during challenges remain poorly un...

The enteric nervous system is a vast network of nerves built into the walls of the intestine. A new study adds to accumulating evidence showing that the ENS works closely with the immune system to hel...

Metagenomic analysis of the gut microbiome of people with human immunodeficiency virus (HIV), from three distinct cohorts, revealed infection- and antiretroviral drug-linked alterations, which may con...

RAMP3, a component of the receptor for the neuropeptide CGRP, has a cell-intrinsic role in T helper type 1 cell fate determination.