Christoph Schwarz
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electro-like.bsky.social
Christoph Schwarz
@electro-like.bsky.social
110 followers 150 following 11 posts
Nephrologist, interest in: electrolyte disorders and kidney stones
Posts Replies Media Videos
Reposted by Christoph Schwarz
alanyuneph.bsky.social
Now out @jclinicalinvest led by Christine_Behm with fantastic team of collaborators👇

We discover a corticomedullary gradient for Ca in kidney and show a critical role for claudin-2, with implications for kidney stone disease.
@kumedcenter.bsky.social

www.jci.org/articles/vie...
December 3, 2025 at 4:54 PM
Reposted by Christoph Schwarz
ckj-era.bsky.social
What to do with key cardiovascular drugs when kidney function worsens?

doi.org/10.1093/ckj/...
What to do with key cardiovascular drugs when kidney function worsens?
Abstract. Patients with advanced cardiovascular kidney metabolic syndrome generally face a high risk of cardiovascular complications. Guideline-directed me
doi.org
November 21, 2025 at 4:01 PM
Reposted by Christoph Schwarz
gregorbond.bsky.social
Immune Monitoring Goes Viral 🦠 Torque Teno Virus
for Immunologic Risk Stratification After Kidney Transplantation

⏩️ new review in TI 🔥

doi.org/10.3389/ti.2...
#ttvguide
November 14, 2025 at 7:15 AM
Reposted by Christoph Schwarz
hjanders.bsky.social
The fundamental difference between water and salt water (volume) was better known at the time of Homer Smith, where they wondered how the salmon can start and end life in fresh water while spending most of life in salt water
November 3, 2025 at 11:55 AM
Reposted by Christoph Schwarz
davidsas.bsky.social
I'm super proud of this work detailing the results of genetic testing in hundreds of kidney stone formers. We identified genetic causes for stones in 34% of those tested (47% if < 16 y.o.). So thankful for such great collaborators & patients! journals.lww.com/cjasn/fullte... #nephrology #mayoclinic
journals.lww.com
October 27, 2025 at 9:46 PM
Reposted by Christoph Schwarz
ajkd.bsky.social
Perspective by Richard H. Sterns and Helbert Rondon-Berrios:

Revisiting New Data on the Mortality Benefit of Rapid Correction of Hyponatremia: Déjà vu All Over Again

bit.ly/42Sl41K
Potential confounders in studies identifying associations between plasma sodium correction rates and mortality. Na = sodium, AVP = arginine vasopressin A) A perceived causal relationship between an exposure and an outcome can be distorted by a third variable, known as a confounder. B) The serum sodium correction rate is the exposure, mortality is the outcome, and certain comorbidities and their severity act as confounders influencing both variables. C) Advanced stages cirrhosis, heart failure, and cancer are linked to higher mortality risk, sustained AVP release, and reduced kidney function, leading to impaired water excretion and slow serum sodium correction. D) In early stages of these conditions—or in their absence—patients exhibit better survival and, because hyponatremia is usually the result of reversible conditions with relatively preserved kidney function, serum sodium can rise rapidly through large-volume water diuresis.
October 23, 2025 at 4:03 PM
Reposted by Christoph Schwarz
daniel-batlle.bsky.social
Thanks to @asnpublications.bsky.social for highlighting our feature on a new syndrome of renal tubular alkalosis! www.kidneynews.org/view/journal... @nu-nephrology.bsky.social @nufeinbergmed.bsky.social
October 16, 2025 at 3:28 PM
electro-like.bsky.social
doi.org/10.1172/JCI1....
distal renal tubular alkalosis - I have been waiting for this publication for years😉
JCI - A gain-of-function mutation in ATP6V0A4 drives primary distal renal tubular alkalosis with enhanced V-ATPase activity
doi.org
October 15, 2025 at 5:37 PM
Reposted by Christoph Schwarz
kidneyboy.bsky.social
New episode of Channel Your Enthusiasm, part 2 of 3 on metabolic acidosis. Episode with chapter art, chapters, and fully referenced

www.rosebook.club/episodes/202...
October 11, 2025 at 8:05 PM
Reposted by Christoph Schwarz
joshleisring.bsky.social
I can't this question, but it gives me a good excuse to mention the 1970s study by Oliver et al demonstrating that high levels of renin / aldosterone alone don't drive blood pressure. It's some combination of salt+RAAS+(?). pubmed.ncbi.nlm.nih.gov/1132118/ #NephJC
May 28, 2025 at 2:11 AM
Reposted by Christoph Schwarz
hjanders.bsky.social
Now online in @ndt-era.bsky.social

Transition of pts with hereditary nephropathies from pediatric to adult care
from WG Genes&Kidney of ERA and ESPN

🧐To improve health outcomes, pt empowerment, and engagement for young people with CKD.

▶️ academic.oup.com/ndt/article-...
September 12, 2025 at 7:42 AM
Reposted by Christoph Schwarz
ajkd.bsky.social
Core Curriculum by Biff F. Palmer and Deborah J. Clegg:

Mixed Acid-Base Disturbances: Core Curriculum 2025

bit.ly/Palmer25CC (FREE)
Development of respiratory alkalosis and increased anion gap metabolic acidosis in salicylate poisoning.
September 11, 2025 at 10:00 PM
Reposted by Christoph Schwarz
natrevneph.nature.com
Kidney stone disease: risk factors, pathophysiology and management go.nature.com/47hmWEe

@danfuster.bsky.social
@sarahhowles.bsky.social
Kidney stone disease: risk factors, pathophysiology and management - Nature Reviews Nephrology
This Review discusses the pathophysiology of kidney stone formation and examines the contribution of urinary risk factors and genetic variants. The authors also consider current approaches to the mana...
go.nature.com
August 27, 2025 at 9:37 AM
Reposted by Christoph Schwarz
hswapnil.medsky.social
RIP Nicolas Madias

Of the Adrogue-Madias formula and much more

I don’t know he wrote three textbooks as a medical student!

www.kidney-international.org/article/S008...
In @kidneyint.bsky.social

#NephSky
August 23, 2025 at 1:22 AM
electro-like.bsky.social
Our new paper on acid base in hyperglycaemia is online - thanks to all authors
doi.org/10.1007/s101...
Acid–base and electrolyte disorders in patients with hyperglycaemia: a monocentric, observational study - Clinical and Experimental Nephrology
Background Acute hyperglycaemia is often accompanied by acid–base and electrolyte disorders as well as changes in serum osmolality which have a significant clinical impact. This study explores the pre...
doi.org
August 19, 2025 at 4:44 PM
Reposted by Christoph Schwarz
jci.org
No stone goes unturned in the search for risk-associated variants in kidney stone disease—

@celovegrove.bsky.social @sarahhowles.bsky.social & team identify three biologic pathways that underlie ~11-19% of common causes of stone formation: buff.ly/INjAjLy
August 9, 2025 at 12:04 PM
Reposted by Christoph Schwarz
asnpublications.bsky.social
Advances in genetics have shed light on many pathways and genes implicated in pediatric kidney diseases, showing the pivotal role of genetic counseling and testing. kidney.pub/KN1707-11 kidney.pub/KN-Genetics #ASNKidneyNews
July 23, 2025 at 4:00 PM
Reposted by Christoph Schwarz
janewit-thekidgene.bsky.social
🧬Introducing our first-ever handbook of genetic nephrology, with free download until 8/2025

authors.elsevier.com/a/1lSgWzcYo6...

@andrewmallett8.bsky.social and I saw a gap in foundational reading of genetic nephrology and decided to gather articles that clinician and learners can all enjoy
authors.elsevier.com
July 19, 2025 at 3:37 PM
Reposted by Christoph Schwarz
pulmcrit.bsky.social
swear I’m not making this up:

we’re called to see a patient with severe AKI and K=8.5 with ECG changes

exam shows a patient lying in bed next to a bannana

SIR, STEP AWAY FROM THE BANNANA
July 18, 2025 at 2:03 PM
electro-like.bsky.social
link.springer.com/article/10.1...
Sodium–chloride difference is not strongly correlated with base excess in chronic kidney disease: an anion gap problem - International Urology and Nephrology
Introduction The prevalence of metabolic acidosis is high in patients with chronic kidney disease (CKD). For the diagnosis, a blood gas analysis is necessary, but not always available. The aim of the ...
link.springer.com
July 10, 2025 at 10:39 AM
electro-like.bsky.social
Water and electrolyte homeostasis during decongestion in heart failure - Van den Eynde - European Journal of Heart Failure - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
from heart to kidney - very nice review
Water and electrolyte homeostasis during decongestion in heart failure
In heart failure, sodium retention generally occurs out of proportion to water retention and may occur disproportionate to chloride retention, requiring excretion of other cations (i.e. potassium, ma...
onlinelibrary.wiley.com
June 28, 2025 at 9:21 AM
electro-like.bsky.social
JCI - Genetic variants predisposing to increased risk of kidney stone disease www.jci.org/articles/vie...
How many genes are necessary to create a kidney stone ?
JCI - Genetic variants predisposing to increased risk of kidney stone disease
www.jci.org
June 7, 2025 at 9:14 AM
Reposted by Christoph Schwarz
gregorbond.bsky.social
torque teno virus 🦠 load predicts malignoma post kidney TX 💪

👏 carsten herz at #era25

viruses 🦠 can be 🦸 superheros
TTVbased immune monitoring
#TTVguide
June 6, 2025 at 3:49 PM
Reposted by Christoph Schwarz
kidneyboy.bsky.social
This was a fun article to work on. Hope you enjoy it.

Things We Do for No Reason™: Avoiding IV iodinated contrast material in patients with acute kidney injury or chronic kidney disease Journal of Hospital Medicine
shmpublications.onlinelibrary.wiley.com/doi/10.1002/...
Things We Do for No Reason™: Avoiding intravenous iodinated contrast material in patients with acute kidney injury or chronic kidney disease
Click on the article title to read more.
shmpublications.onlinelibrary.wiley.com
June 1, 2025 at 11:25 PM
Reposted by Christoph Schwarz
ukidney.bsky.social
Update to our supersaturation and kidney stone risk assessment tool:

We have added calcium to citrate ratios to the result section providing even greater risk assessment tools to the kit. Thanks very much to Vladimir Belostotsky for the idea!

ukidney.com/calculators/...
May 29, 2025 at 4:26 PM