Miki Ebisuya
@ebisuyamiki.bsky.social
Synthetic developmental biologist at PoL TU Dresden. Cross-species comparison and manipulation of the ORGANOID ZOO.
https://physics-of-life.tu-dresden.de/team/pol-groups/ebisuya
https://physics-of-life.tu-dresden.de/team/pol-groups/ebisuya
Pinned
Miki Ebisuya
@ebisuyamiki.bsky.social
· Oct 8
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...
1/
doi.org/10.1101/2025...
Reposted by Miki Ebisuya
Stephen R. Frankenberg et al. (2025)
Unearthing the secrets of Australia’s most enigmatic and cryptic mammal, the marsupial mole
Science Advances 11(1): eado4140
DOI: 10.1126/sciadv.ado4140
www.science.org/doi/10.1126/...
Unearthing the secrets of Australia’s most enigmatic and cryptic mammal, the marsupial mole
Science Advances 11(1): eado4140
DOI: 10.1126/sciadv.ado4140
www.science.org/doi/10.1126/...
Unearthing the secrets of Australia’s most enigmatic and cryptic mammal, the marsupial mole
The marsupial mole’s genome unearths their phylogenetic status and insights into convergent evolution in subterranean mammals.
www.science.org
January 5, 2025 at 3:08 PM
Stephen R. Frankenberg et al. (2025)
Unearthing the secrets of Australia’s most enigmatic and cryptic mammal, the marsupial mole
Science Advances 11(1): eado4140
DOI: 10.1126/sciadv.ado4140
www.science.org/doi/10.1126/...
Unearthing the secrets of Australia’s most enigmatic and cryptic mammal, the marsupial mole
Science Advances 11(1): eado4140
DOI: 10.1126/sciadv.ado4140
www.science.org/doi/10.1126/...
Reposted by Miki Ebisuya
Programmed seasonal brain shrinkage in the common shrew via water loss without cell death: Current Biology www.cell.com/current-biol...
September 3, 2025 at 1:01 PM
Programmed seasonal brain shrinkage in the common shrew via water loss without cell death: Current Biology www.cell.com/current-biol...
Reposted by Miki Ebisuya
ゲノム言語モデルによる遺伝子のデザイン
機能的に関連する遺伝子同士が近くに集まって存在する性質を活かして、ゲノムの文脈を理解するようなモデルを構築。遺伝子の機能探索や新規の毒素タンパク質やCRISPR阻害タンパク質をデザイン可能。公開データベースも整備。
時代の進歩に目が回ります、、
www.nature.com/articles/s41...
機能的に関連する遺伝子同士が近くに集まって存在する性質を活かして、ゲノムの文脈を理解するようなモデルを構築。遺伝子の機能探索や新規の毒素タンパク質やCRISPR阻害タンパク質をデザイン可能。公開データベースも整備。
時代の進歩に目が回ります、、
www.nature.com/articles/s41...
Semantic design of functional de novo genes from a genomic language model - Nature
By learning a semantics of gene function based on genomic context, the genomic language model Evo autocompletes DNA prompts to generate novel genes encoding protein and RNA molecules with defined…
www.nature.com
November 20, 2025 at 10:00 AM
ゲノム言語モデルによる遺伝子のデザイン
機能的に関連する遺伝子同士が近くに集まって存在する性質を活かして、ゲノムの文脈を理解するようなモデルを構築。遺伝子の機能探索や新規の毒素タンパク質やCRISPR阻害タンパク質をデザイン可能。公開データベースも整備。
時代の進歩に目が回ります、、
www.nature.com/articles/s41...
機能的に関連する遺伝子同士が近くに集まって存在する性質を活かして、ゲノムの文脈を理解するようなモデルを構築。遺伝子の機能探索や新規の毒素タンパク質やCRISPR阻害タンパク質をデザイン可能。公開データベースも整備。
時代の進歩に目が回ります、、
www.nature.com/articles/s41...
Reposted by Miki Ebisuya
📝 Online now - the Spotlight "Unlocking the protein code: how our organs age across a lifetime" from Dongxue Wang and Jing Yang.
#Proteostasis #Aging #BiologicalClocks #Proteomics
Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...
#Proteostasis #Aging #BiologicalClocks #Proteomics
Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...
November 18, 2025 at 9:35 PM
📝 Online now - the Spotlight "Unlocking the protein code: how our organs age across a lifetime" from Dongxue Wang and Jing Yang.
#Proteostasis #Aging #BiologicalClocks #Proteomics
Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...
#Proteostasis #Aging #BiologicalClocks #Proteomics
Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...
第5回 羽ばたく女性研究者賞 への応募受付中です。基礎研究あるいは研究開発に関わる、博士課程から独立直後あたりのキャリアステージの女性研究者の、表彰と応援が目的です。12月10日締め切りなので、自ら応募する、あるいは身近な対象者の背中を押してあげてください
www.jst.go.jp/diversity/re...
www.jst.go.jp/diversity/re...
第5回 羽ばたく女性研究者賞（マリア・スクウォドフスカ＝キュリー賞）
www.jst.go.jp
November 19, 2025 at 10:18 AM
第5回 羽ばたく女性研究者賞 への応募受付中です。基礎研究あるいは研究開発に関わる、博士課程から独立直後あたりのキャリアステージの女性研究者の、表彰と応援が目的です。12月10日締め切りなので、自ら応募する、あるいは身近な対象者の背中を押してあげてください
www.jst.go.jp/diversity/re...
www.jst.go.jp/diversity/re...
Reposted by Miki Ebisuya
Comparative genomics indicate multiple genetic routes to the evolution of torpor in placental mammals https://www.biorxiv.org/content/10.1101/2025.11.18.689136v1
November 19, 2025 at 5:32 AM
Comparative genomics indicate multiple genetic routes to the evolution of torpor in placental mammals https://www.biorxiv.org/content/10.1101/2025.11.18.689136v1
最近のイチオシ漫画は「星旅少年」。話の展開を追うというよりは、綺麗な青色・小物のディテール・いいかんじのシチュエーションなどを、じっくり眺めて楽しむコミックアート。寝る前に部屋を暗くして電子書籍で読むと最高です。漫画の新しい楽しみ方を知りましたありがとう
comics.pie.co.jp/series/hoshi...
comics.pie.co.jp/series/hoshi...
星旅少年 | PIE COMICS
住民の多くが眠ってしまった星を「まどろみの星」と呼んだ。「まどろみの星」を訪ね、残された文化を記憶・保存する、プラネタリウム・ゴースト・トラベル社（通称PGT 社）の星旅人（ほしたびびと）・登録ナンバー303の物語。眠らない少年303と静かな夜の旅に出かけてみませんか。
comics.pie.co.jp
November 18, 2025 at 7:13 PM
最近のイチオシ漫画は「星旅少年」。話の展開を追うというよりは、綺麗な青色・小物のディテール・いいかんじのシチュエーションなどを、じっくり眺めて楽しむコミックアート。寝る前に部屋を暗くして電子書籍で読むと最高です。漫画の新しい楽しみ方を知りましたありがとう
comics.pie.co.jp/series/hoshi...
comics.pie.co.jp/series/hoshi...
Reposted by Miki Ebisuya
🚨 Last call! Short talk abstracts & scholarship apps for Stem Cell Models in Embryology are due Nov 18 (11:59pm MST). Don’t miss your chance to join the lineup this February in Pacific Grove, CA.
🎥 youtu.be/g2DGgU2r7ao
🔗 keysym.us/KSEmbryology26
@jun-wu-lab.bsky.social @ebisuyamiki.bsky.social
🎥 youtu.be/g2DGgU2r7ao
🔗 keysym.us/KSEmbryology26
@jun-wu-lab.bsky.social @ebisuyamiki.bsky.social
Stem Cell Models in Embryology Meeting Promo
YouTube video by KeystoneSymposia
youtu.be
November 14, 2025 at 4:57 PM
🚨 Last call! Short talk abstracts & scholarship apps for Stem Cell Models in Embryology are due Nov 18 (11:59pm MST). Don’t miss your chance to join the lineup this February in Pacific Grove, CA.
🎥 youtu.be/g2DGgU2r7ao
🔗 keysym.us/KSEmbryology26
@jun-wu-lab.bsky.social @ebisuyamiki.bsky.social
🎥 youtu.be/g2DGgU2r7ao
🔗 keysym.us/KSEmbryology26
@jun-wu-lab.bsky.social @ebisuyamiki.bsky.social
Reposted by Miki Ebisuya
“substantial phenotypic diversity already existed in early Holocene dogs” nice #domestixation study by @gregerlarson.bsky.social & collaborators in @science.org 🧪🐶🐾
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
The emergence and diversification of dog morphology
Dogs exhibit an exceptional range of morphological diversity as a result of their long-term association with humans. Attempts to identify when dog morphological variation began to expand have been con...
www.science.org
November 14, 2025 at 12:32 PM
“substantial phenotypic diversity already existed in early Holocene dogs” nice #domestixation study by @gregerlarson.bsky.social & collaborators in @science.org 🧪🐶🐾
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Miki Ebisuya
Carnivorous 'death-ball' among odd deep-sea finds. 🧪 www.bbc.co.uk/news/article...
Carnivorous 'death-ball' sponge is team's oddest deep-sea find
The unusual creature lurks more than two miles (3.2km) deep in a trench in the Southern Ocean.
www.bbc.co.uk
November 11, 2025 at 6:56 AM
Carnivorous 'death-ball' among odd deep-sea finds. 🧪 www.bbc.co.uk/news/article...
Reposted by Miki Ebisuya
What is the origin of diversity in allometric laws scaling across species? Check our new paper led by Andrea Tabi where
we propose a new theory of metabolic scaling grounded in thermodynamics and stochastic fluctuations at the cellular level.
www.biorxiv.org/content/10.1...
we propose a new theory of metabolic scaling grounded in thermodynamics and stochastic fluctuations at the cellular level.
www.biorxiv.org/content/10.1...
November 9, 2025 at 2:39 AM
What is the origin of diversity in allometric laws scaling across species? Check our new paper led by Andrea Tabi where
we propose a new theory of metabolic scaling grounded in thermodynamics and stochastic fluctuations at the cellular level.
www.biorxiv.org/content/10.1...
we propose a new theory of metabolic scaling grounded in thermodynamics and stochastic fluctuations at the cellular level.
www.biorxiv.org/content/10.1...
Reposted by Miki Ebisuya
And you can of course also go through to the q.e.d website: www.qedscience.com
q.e.d Science
Critical Thinking AI for constructive criticism and science evaluation
www.qedscience.com
November 6, 2025 at 3:05 PM
And you can of course also go through to the q.e.d website: www.qedscience.com
Reposted by Miki Ebisuya
“If your heart is beating really strong and fast, and you’re in a fear state, you don’t want to be sensitive to pain. You want to be able to run over broken twigs and glass to escape the threat,” said neuroscientist Sarah Garfinkel. www.quantamagazine.org/how-your-hea...
October 31, 2025 at 10:59 PM
“If your heart is beating really strong and fast, and you’re in a fear state, you don’t want to be sensitive to pain. You want to be able to run over broken twigs and glass to escape the threat,” said neuroscientist Sarah Garfinkel. www.quantamagazine.org/how-your-hea...
Reposted by Miki Ebisuya
🌟 Countdown to Nov 4 (11:59pm MT)! Submit your short talk or scholarship app for #KSEmbryology26: Stem Cell Models in Embryology. Join @jun-wu-lab.bsky.social, @ebisuyamiki.bsky.social & global experts
🎥 youtu.be/hKhc2VrbFj0
🔗 keysym.us/KSEmbryology26
#KSEmbryology26 #embryology #stemcells
🎥 youtu.be/hKhc2VrbFj0
🔗 keysym.us/KSEmbryology26
#KSEmbryology26 #embryology #stemcells
KSQA: Dr. Jun Wu (Stem Cell Models in Embryology)
YouTube video by KeystoneSymposia
youtu.be
October 31, 2025 at 5:07 PM
🌟 Countdown to Nov 4 (11:59pm MT)! Submit your short talk or scholarship app for #KSEmbryology26: Stem Cell Models in Embryology. Join @jun-wu-lab.bsky.social, @ebisuyamiki.bsky.social & global experts
🎥 youtu.be/hKhc2VrbFj0
🔗 keysym.us/KSEmbryology26
#KSEmbryology26 #embryology #stemcells
🎥 youtu.be/hKhc2VrbFj0
🔗 keysym.us/KSEmbryology26
#KSEmbryology26 #embryology #stemcells
Despite higher cell numbers and longer lifespans, large animals don’t have a higher cancer rate: Peto’s paradox. Elephants carry extra copies of tumor suppressor genes, while whales rely on enhanced DNA repair mechanisms! It’s fascinating that nature found different solutions to the same problem
Nature research paper: Evidence for improved DNA repair in long-lived bowhead whale
go.nature.com/4oNJSAG
go.nature.com/4oNJSAG
Evidence for improved DNA repair in long-lived bowhead whale - Nature
Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.
go.nature.com
October 30, 2025 at 12:26 PM
Despite higher cell numbers and longer lifespans, large animals don’t have a higher cancer rate: Peto’s paradox. Elephants carry extra copies of tumor suppressor genes, while whales rely on enhanced DNA repair mechanisms! It’s fascinating that nature found different solutions to the same problem
Reposted by Miki Ebisuya
From the nine-inch pygmy shark to a whale shark, the largest living fish, all sharks have the same surface area to volume ratio: a metric that might be a universal proportion across the natural world.
www.quantamagazine.org/shark-data-s...
www.quantamagazine.org/shark-data-s...
Shark Data Suggests Animals Scale Like Geometric Objects | Quanta Magazine
Despite their wide variety of sizes, niches and shapes, sharks scale geometrically, pointing to possible fundamental constraints on evolution.
www.quantamagazine.org
October 27, 2025 at 3:00 PM
From the nine-inch pygmy shark to a whale shark, the largest living fish, all sharks have the same surface area to volume ratio: a metric that might be a universal proportion across the natural world.
www.quantamagazine.org/shark-data-s...
www.quantamagazine.org/shark-data-s...
Reposted by Miki Ebisuya
Join us @ #IETS2026 for our CANDES Precon keynote speaker, Miki Ebisuya, PhD (Physics of Life Dresden) 🎉.
“Stem cell zoo: A platform for exploring species-specific biological time” 🔬⏰
Don't miss out—register by Dec 15 📆 to lock in early bird pricing!
🔗 https://bit.ly/3ILbB5r
“Stem cell zoo: A platform for exploring species-specific biological time” 🔬⏰
Don't miss out—register by Dec 15 📆 to lock in early bird pricing!
🔗 https://bit.ly/3ILbB5r
October 27, 2025 at 2:01 PM
Join us @ #IETS2026 for our CANDES Precon keynote speaker, Miki Ebisuya, PhD (Physics of Life Dresden) 🎉.
“Stem cell zoo: A platform for exploring species-specific biological time” 🔬⏰
Don't miss out—register by Dec 15 📆 to lock in early bird pricing!
🔗 https://bit.ly/3ILbB5r
“Stem cell zoo: A platform for exploring species-specific biological time” 🔬⏰
Don't miss out—register by Dec 15 📆 to lock in early bird pricing!
🔗 https://bit.ly/3ILbB5r
Reposted by Miki Ebisuya
Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
October 26, 2025 at 2:01 AM
Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Reposted by Miki Ebisuya
#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel!
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
2026 Lake Conference: Modeling Life from Cells to Tissues
Join the Allen Institute for Cell Science and Circuit Neuroscience Basel in Seattle, Washington, April 20–22, 2026, for a 3 day conference, Modeling...
alleninstitute.org
October 20, 2025 at 9:33 PM
#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel!
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
Reposted by Miki Ebisuya
“Cellular Olympics” our catalog of freeky ultra fast cellular superhero’s is freely available “Ann Rev of microbiology”
www.annualreviews.org/content/jour...
This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪
www.annualreviews.org/content/jour...
This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪
October 24, 2025 at 10:57 AM
“Cellular Olympics” our catalog of freeky ultra fast cellular superhero’s is freely available “Ann Rev of microbiology”
www.annualreviews.org/content/jour...
This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪
www.annualreviews.org/content/jour...
This is a compilation of world’s fastest single cell organisms - enjoy this buffet of rare delightful protists with mind bending speeds. 🧪
Reposted by Miki Ebisuya
mStayRose is published in JBC 🥳🎉
Congratulations @wsctt.bsky.social @sporemohan.bsky.social and team for the monumental effort to make a non-natural amino acid incorporating fluorescent protein accessible. It's based on mStayGold, bright, and photostable:
www.jbc.org/article/S002...
Congratulations @wsctt.bsky.social @sporemohan.bsky.social and team for the monumental effort to make a non-natural amino acid incorporating fluorescent protein accessible. It's based on mStayGold, bright, and photostable:
www.jbc.org/article/S002...
StayRose: a photostable StayGold derivative red-shifted by genetic code expansion
Photobleaching of fluorescent proteins often limits the acquisition of high-quality
images in microscopy. StayGold, a novel dimeric green fluorescent protein recently
monomerised through sequence engi...
www.jbc.org
October 22, 2025 at 4:58 PM
mStayRose is published in JBC 🥳🎉
Congratulations @wsctt.bsky.social @sporemohan.bsky.social and team for the monumental effort to make a non-natural amino acid incorporating fluorescent protein accessible. It's based on mStayGold, bright, and photostable:
www.jbc.org/article/S002...
Congratulations @wsctt.bsky.social @sporemohan.bsky.social and team for the monumental effort to make a non-natural amino acid incorporating fluorescent protein accessible. It's based on mStayGold, bright, and photostable:
www.jbc.org/article/S002...
Reposted by Miki Ebisuya
🚨 Late preprint alert!
Why do biological process rates scale nonlinearly with temperature, deviating from the straight line on an Arrhenius plot? The key may lie in their inherent complexity!
More in thread and here: doi.org/10.1101/2025...
Why do biological process rates scale nonlinearly with temperature, deviating from the straight line on an Arrhenius plot? The key may lie in their inherent complexity!
More in thread and here: doi.org/10.1101/2025...
October 22, 2025 at 10:29 AM
🚨 Late preprint alert!
Why do biological process rates scale nonlinearly with temperature, deviating from the straight line on an Arrhenius plot? The key may lie in their inherent complexity!
More in thread and here: doi.org/10.1101/2025...
Why do biological process rates scale nonlinearly with temperature, deviating from the straight line on an Arrhenius plot? The key may lie in their inherent complexity!
More in thread and here: doi.org/10.1101/2025...
Reposted by Miki Ebisuya
This week’s round-up spans species from birds to sheep, and now, fittingly, to dogs!
We dive into a new study from Japanese researchers, who have successfully established culture conditions for #canine iPSCs.
🐕 Article: https://bit.ly/4gA5zkC
🐩 Discussion: https://bit.ly/4qfiME4
We dive into a new study from Japanese researchers, who have successfully established culture conditions for #canine iPSCs.
🐕 Article: https://bit.ly/4gA5zkC
🐩 Discussion: https://bit.ly/4qfiME4
October 20, 2025 at 4:48 PM
This week’s round-up spans species from birds to sheep, and now, fittingly, to dogs!
We dive into a new study from Japanese researchers, who have successfully established culture conditions for #canine iPSCs.
🐕 Article: https://bit.ly/4gA5zkC
🐩 Discussion: https://bit.ly/4qfiME4
We dive into a new study from Japanese researchers, who have successfully established culture conditions for #canine iPSCs.
🐕 Article: https://bit.ly/4gA5zkC
🐩 Discussion: https://bit.ly/4qfiME4
Reposted by Miki Ebisuya
⏰ Last chance! Apply for a scholarship or submit your short talk abstract for Stem Cell Models in Embryology by Oct 21 (11:59pm MT). Join @jun-wu-lab.bsky.social & @ebisuyamiki.bsky.social this Feb for cutting-edge #stemcells & #embryology.
🎥 youtu.be/hKhc2VrbFj0 🔗 keysym.us/KSEmbryology26
🎥 youtu.be/hKhc2VrbFj0 🔗 keysym.us/KSEmbryology26
KSQA: Dr. Jun Wu (Stem Cell Models in Embryology)
YouTube video by KeystoneSymposia
youtu.be
October 20, 2025 at 5:25 PM
⏰ Last chance! Apply for a scholarship or submit your short talk abstract for Stem Cell Models in Embryology by Oct 21 (11:59pm MT). Join @jun-wu-lab.bsky.social & @ebisuyamiki.bsky.social this Feb for cutting-edge #stemcells & #embryology.
🎥 youtu.be/hKhc2VrbFj0 🔗 keysym.us/KSEmbryology26
🎥 youtu.be/hKhc2VrbFj0 🔗 keysym.us/KSEmbryology26
Reposted by Miki Ebisuya
陸上生活に適応する耐圧メカニズム
陸上で生活する四足動物に存在し、足底の皮膚に特異的に発現する因子SLURP1を発見。SLURP1がないと、機械的圧力によって皮膚の過形成性が起きる。SLURP1は分泌されると考えられていたがERでCaレベルを制御
着眼点が面白いです
www.cell.com/cell/fulltex...
陸上で生活する四足動物に存在し、足底の皮膚に特異的に発現する因子SLURP1を発見。SLURP1がないと、機械的圧力によって皮膚の過形成性が起きる。SLURP1は分泌されると考えられていたがERでCaレベルを制御
着眼点が面白いです
www.cell.com/cell/fulltex...
A mechano-resistance mechanism in skin adapts to terrestrial locomotion
An evolutionarily emerged ER-based mechano-resistance mechanism supports epidermal function under mechanical pressure. SLURP1, an ER membrane protein, preserves SERCA2b activity and calcium…
www.cell.com
October 18, 2025 at 10:01 AM
陸上生活に適応する耐圧メカニズム
陸上で生活する四足動物に存在し、足底の皮膚に特異的に発現する因子SLURP1を発見。SLURP1がないと、機械的圧力によって皮膚の過形成性が起きる。SLURP1は分泌されると考えられていたがERでCaレベルを制御
着眼点が面白いです
www.cell.com/cell/fulltex...
陸上で生活する四足動物に存在し、足底の皮膚に特異的に発現する因子SLURP1を発見。SLURP1がないと、機械的圧力によって皮膚の過形成性が起きる。SLURP1は分泌されると考えられていたがERでCaレベルを制御
着眼点が面白いです
www.cell.com/cell/fulltex...