Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
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dudinlab.bsky.social
Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
@dudinlab.bsky.social
Asst. Prof. at UNIGE

Evolutionary cell biology & multicellular developmental diversity of protists.

www.dudinlab.com

#Ichthyosporea, #Multicellularity, #Evolution, #Embryo, #Development, #Protist, #UExM, #Cytoskeleton, #Actin, #Expansion #Microscopy
Pinned
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky

www.cell.com/cell/fulltex...
Very happy to see this out there ! Amazing work by @zjmaggiexu.bsky.social @amyweeks.bsky.social & @cellraiser.bsky.social!

All #ProtistsOnSky are amazing, but when I bumbed into @zjmaggiexu.bsky.social & her poster 2y ago at a #GRC conference, I got the urge to attempt #ExpnasionMicroscopy!
n/1
How do cells adapt morphology to function? In a 🔥 preprint by @zjmaggiexu.bsky.social , with @dudinlab.bsky.social and @amyweeks.bsky.social , we identify a self-organizing single-cell morphology circuit that optimizes the feeding trap structure of the suctorian P. collini. 🧵 tinyurl.com/4k8nv926
November 18, 2025 at 5:19 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature Genetics
Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.
www.nature.com
November 18, 2025 at 12:00 PM
Big Congrats @jlsteenwyk.bsky.social & Nicole for this amazing and impressive work !
I hope it settles the debate for sometime !
November 13, 2025 at 8:38 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
Let me use this as an opportunity to talk about Jordi et al's very cool paper, now out in PNAS 🧪:

pmc.ncbi.nlm.nih.gov/articles/PMC...

You can read our news and views here: www.pnas.org/doi/10.1073/...
November 13, 2025 at 4:13 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
We are looking for a PhD student to work on an exciting plastid endosymbiosis in microbial eukaryotes. This position involves sampling, exciting microscopy such as CARDFISH, ExM and FIBSEM, single-cell transcriptomics and more. #protistsonsky 1/2
November 12, 2025 at 9:50 AM
Come and Join Us.
Not only will it be fun, but you will be learning a lot of methods & travel some more ;)!
November 12, 2025 at 9:51 AM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
Weekend #Plankton Factoid 🦠🦐
November 8, 2025 at 2:53 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
November 7, 2025 at 1:35 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
An Asgard archaeon with internal membrane compartments

Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!

www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
Single-nucleus profiling highlights the all-brain echinoderm nervous system
A sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.
www.science.org
November 5, 2025 at 7:03 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
1/ Preprint alert:

🌾 The developing leaf of the wild grass Brachypodium distachyon at single-cell resolution

👉 doi.org/10.1101/2025...
A 70k-cell single-cell RNA-seq atlas of the developing grass leaf—from the shoot meristem to mature leaf tissues. @cerealcell.bsky.social @lbmountain.bsky.social
November 5, 2025 at 12:32 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
(1/2) A new study from EMBL researchers and their collaborators provides unprecedented insights into the cellular architecture of over 200 species of plankton – tiny but ecologically critical marine organisms – using ultrastructure expansion microscopy.

Learn more: www.cell.com/cell/fulltex...
November 4, 2025 at 8:30 AM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
November 3, 2025 at 1:34 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
This paper has been a must! Great collaboration with @mkrupovic.bsky.social and @yifanzhou.bsky.social, a N&V by a legend of halophilic archaea tinyurl.com/yc3dcv72, and one picture of one of our expeditions to Dallol making the cover of the November issue of @natmicrobiol.nature.com

rdcu.be/eLtCH
November 2, 2025 at 5:52 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
So a big day for #microeukaryote #imaging. To finish "en beaute" a small video to share the behind the scenes of this first work. Such an exciting time to be a #marine #microbiologist !!
October 31, 2025 at 3:27 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n
#ProtistsOnSky
tinyurl.com/2zxaund7
October 31, 2025 at 3:27 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
Now online! Charting the landscape of cytoskeletal diversity in microbial eukaryotes
Charting the landscape of cytoskeletal diversity in microbial eukaryotes
An imaging resource of over 200 microbial eukaryotic species provides a glimpse into the remarkable universe of cytoskeletal diversity.
dlvr.it
October 31, 2025 at 2:59 PM
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky

www.cell.com/cell/fulltex...
October 31, 2025 at 2:42 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
New preprint out! Evolutionarily conserved transcriptional regulators control monoaminergic neuron development.
We uncover how ancient regulatory programs orchestrate the neurons that produce serotonin and dopamine across 550 million years of evolution.
doi.org/10.1101/2025...
Evolutionarily conserved transcriptional regulators control monoaminergic neuron development
To what extent conserved developmental programs specify homologous cell types is a central question in biology. Here, we address this by focusing on reconstructing monoaminergic neuron development in ...
doi.org
October 30, 2025 at 9:42 AM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
📣 We are moving to Barcelona to join the amazing @crg.eu and explore how centrosomes & cilia work, evolve & respond to the environment. We are looking for
PhD students www.crg.eu/en/content/t...
Postdocs gimm.pt/jobs/postdoc...
Other calls to open, also for an experienced lab manager.
Get in touch!
October 30, 2025 at 1:15 PM
Reposted by Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience

Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E

@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
We are growing :)
A new BIG baby has just landed. 🤩
October 28, 2025 at 9:49 AM
Anyone has a clue why #ATCC is so expensive ? I got a quote for 2 species, without any guarantee of growth for >1900 € ?

Just why ? these species were isolated and deposited using public money, why is it so expensive !
October 24, 2025 at 3:50 PM