Lorenzo Galluzzi
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deadoc80.bsky.social
Lorenzo Galluzzi
@deadoc80.bsky.social
40 followers 22 following 0 posts
Scientist, survivor and dog lover
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Reposted by Lorenzo Galluzzi
natcancer.nature.com
Save the date! We are hosting the webinar "Inflammatory cell death and anti-tumor immunity". Join our speakers Dmitri Krysko, Judy Lieberman, Lorenzo Galluzzi and Pascal Meier
@deadoc80.bsky.social @meierlabicr.bsky.social
📅 Tuesday 14th Oct 2025
⏰ 16.00 PM (GMT+1)
cassyni.com/events/QAERn...
Cassyni | Science starts with a seminar
Seamlessly organise, run and publish academic research seminars. Get started in minutes.
cassyni.com
October 1, 2025 at 2:53 PM
Reposted by Lorenzo Galluzzi
abhishekgarglab.bsky.social
📌In #September @natrevimmunol.nature.com issue, read our #comprehensive #Review: "The #Diversity of #CD8+ T #cell #dysfunction in #cancer and #viral #infection"

⏩Read: www.nature.com/articles/s41...

🤝Result of fruitful #Collaboration w/ @deadoc80.bsky.social @labliston.bsky.social & Kellie Smith!
August 31, 2025 at 11:49 AM
Reposted by Lorenzo Galluzzi
labwaggoner.bsky.social
Review @natrevmcb.nature.com @deadoc80.bsky.social Regulation of inflammatory processes by caspases
www.nature.com/articles/s41...
July 2, 2025 at 7:54 PM
Reposted by Lorenzo Galluzzi
labwaggoner.bsky.social
IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR+HER2− breast cancer via CX3CR1+ macrophages @natcancer.nature.com @deadoc80.bsky.social
www.nature.com/articles/s43...
IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR+HER2− breast cancer via CX3CR1+ macrophages - Nature Cancer
Petroni et al. report that the infiltration of IL-17A-secreting γδ T cells in the tumor microenvironment coupled with the accumulation of immunosuppressive macrophages is associated with resistance to...
www.nature.com
July 7, 2025 at 7:07 PM
Reposted by Lorenzo Galluzzi
adlunglab.com
CD8+ T cell dysfunction extends beyond exhaustion. This @natrevimmunol review by @deadoc80, Kellie Smith, @labliston & @abhishekgarglab proposes a unified framework encompassing anergy, tolerance, exclusion, and senescence in cancer and infection.
doi.org/10.1038/s415... 🧪
The diversity of CD8+ T cell dysfunction in cancer and viral infection
Nature Reviews Immunology - Beyond exhaustion, CD8+ T cells can adopt various dysfunctional states, including tolerant, anergic, senescent, ignorant and dying states, that compromise their ability...
doi.org
April 15, 2025 at 7:45 AM
Reposted by Lorenzo Galluzzi
labliston.bsky.social
Our @natrevimmunol.bsky.social review with @abhishekgarglab.bsky.social, @deadoc80.bsky.social and Kellie Smith is out!

We attempt to integrate the data on CD8 T cell dysfunction into a new framework of hypofunctionality in cancer and chronic infections!

www.nature.com/articles/s41...
The diversity of CD8+ T cell dysfunction in cancer and viral infection - Nature Reviews Immunology
Beyond exhaustion, CD8+ T cells can adopt various dysfunctional states, including tolerant, anergic, senescent, ignorant and dying states, that compromise their ability to eradicate viruses or tumours...
www.nature.com
April 14, 2025 at 8:53 AM
Reposted by Lorenzo Galluzzi
abhishekgarglab.bsky.social
📢Happy to share our @natrevimmunol.bsky.social article; Result of #collaboration with @deadoc80.bsky.social @labliston.bsky.social & K Smith!
📑Read here: rdcu.be/ehm67
🔥Take🏠msg: Time to move away from narrow concept of #exhausted T cells to other #hypofunctional #states! 1/6🧵
@oncodaily.bsky.social
April 11, 2025 at 5:00 PM
Reposted by Lorenzo Galluzzi
abhishekgarglab.bsky.social
⚡️Happy to share our @cp-cancercell.bsky.social #Preview on this latest research on role of #mitochondrial #metabolism in #tcell #exhaustion in #Cancer!

🙌Kudos to @deadoc80.bsky.social & E. Guilbaud for leading this!

#CancerResearch #Immunology #immunotherapy #Oncology
www.cell.com/cancer-cell/...
Mitochondrial succinate feeds T cell exhaustion in cancer
Mitochondrial fitness is critical for effector CD8+ T cell responses against cancer. In this issue of Cancer Cell, Ma et al. delineate a novel mechanism linking defects in mitochondrial metabolism as ...
www.cell.com
February 10, 2025 at 6:03 PM