Marcin Czerwinski
@czerwinsmarcin.bsky.social
Researcher | glycobiology | blood groups | enviroment | photography digital and analog | Poland
Mutation c.548A>G (p.Asp183Gly) in the gene encoding A-glycosyltransferase results in the A(weak) trait by reducing the number of hydrogen bonds, which leads to decreased protein stability.
tinyurl.com/apj2c6m3
#glycotime
tinyurl.com/apj2c6m3
#glycotime
November 25, 2025 at 10:44 AM
Mutation c.548A>G (p.Asp183Gly) in the gene encoding A-glycosyltransferase results in the A(weak) trait by reducing the number of hydrogen bonds, which leads to decreased protein stability.
tinyurl.com/apj2c6m3
#glycotime
tinyurl.com/apj2c6m3
#glycotime
Interesting report shows that peptidylarginine deiminase 4 (PAD4), an enzyme responsible for citrullination of arginine in rheumatoid arthritis, is activated by glycosaminoglycans released from cartilage, which may exacerbate the symptoms.
tinyurl.com/mrxxhm4y
#glycotime
tinyurl.com/mrxxhm4y
#glycotime
November 24, 2025 at 2:17 PM
Interesting report shows that peptidylarginine deiminase 4 (PAD4), an enzyme responsible for citrullination of arginine in rheumatoid arthritis, is activated by glycosaminoglycans released from cartilage, which may exacerbate the symptoms.
tinyurl.com/mrxxhm4y
#glycotime
tinyurl.com/mrxxhm4y
#glycotime
November 23, 2025 at 9:00 PM
Important paper about the regulation of oligosaccharyltransferase (OST) complexes: conserved N-terminal extension in GRP94 inhibits OST-A shielding the tethered nascent chain from inappropriate OST-B glycosylation.
tinyurl.com/5n6ry6u8
#glycotime
tinyurl.com/5n6ry6u8
#glycotime
November 20, 2025 at 10:16 AM
Important paper about the regulation of oligosaccharyltransferase (OST) complexes: conserved N-terminal extension in GRP94 inhibits OST-A shielding the tethered nascent chain from inappropriate OST-B glycosylation.
tinyurl.com/5n6ry6u8
#glycotime
tinyurl.com/5n6ry6u8
#glycotime
Efficient invasion of Plasmodium falciparum strains (but not P. knowlesi) depends on α(2-3) sialic acid structures within mucin-type O-glycans. C1GALT1 as a key player in malaria?
tinyurl.com/5azvxx8v
#glycotime
#malaria
tinyurl.com/5azvxx8v
#glycotime
#malaria
November 17, 2025 at 10:54 AM
Efficient invasion of Plasmodium falciparum strains (but not P. knowlesi) depends on α(2-3) sialic acid structures within mucin-type O-glycans. C1GALT1 as a key player in malaria?
tinyurl.com/5azvxx8v
#glycotime
#malaria
tinyurl.com/5azvxx8v
#glycotime
#malaria
Important issue!
Big day for foundational glycoRNA research, with two preprints published in Nature EMM. Both urge greater analytical rigour in the field.
1. RNA-associated glycoconjugates highlight potential
ambiguities in glycoRNA analysis
2. Proteins are a source of glycans found in preparations of glycoRNA
1. RNA-associated glycoconjugates highlight potential
ambiguities in glycoRNA analysis
2. Proteins are a source of glycans found in preparations of glycoRNA
#glycotime We hope our b2b publications serve as a heads-up for the #glycoRNA community, and drive the field forward constructively. Links👇
Kim et al. rdcu.be/eP4GQ
@nathanaelbkegel.bsky.social Kegel et al. nature.com/articles/s12276-025-01575-1 (Stefan Bauer lab)
Kim et al. rdcu.be/eP4GQ
@nathanaelbkegel.bsky.social Kegel et al. nature.com/articles/s12276-025-01575-1 (Stefan Bauer lab)
November 17, 2025 at 8:36 AM
Important issue!
November 16, 2025 at 8:29 PM
W Borach Stobrawskich (okolica Ładzy) taki okaz. @piotrgasiorowski.bsky.social, co to takiego?
November 15, 2025 at 2:15 PM
W Borach Stobrawskich (okolica Ładzy) taki okaz. @piotrgasiorowski.bsky.social, co to takiego?
November 14, 2025 at 6:12 PM
Reposted by Marcin Czerwinski
Excited to share our laboratory's research tools to study Siglecs along with some interesting discoveries with these tools. Lot of help from many group, but @zeinab-jc.bsky.social was the major driver of this work. Please reach out if you would like to try them out. www.science.org/doi/10.1126/...
An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function
Siglec-liposomes are a multivalent and modular platform for profiling Siglec ligands and modulating immune cell function.
www.science.org
November 12, 2025 at 9:59 PM
Südtirol/Alto Adige. Strudelkopfelsattel/Selle di Monte Specie (2204 m). Cristallo group in the background.
📷Canon EOS 5
🔘17-40 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomites
📷Canon EOS 5
🔘17-40 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomites
November 12, 2025 at 6:41 PM
Südtirol/Alto Adige. Strudelkopfelsattel/Selle di Monte Specie (2204 m). Cristallo group in the background.
📷Canon EOS 5
🔘17-40 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomites
📷Canon EOS 5
🔘17-40 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomites
Plasmodium falciparum and its elusive EBA-181 red blood cell ligand: requires Neu5Ac or Neu5Gc, with Band 3/anion exchanger 1 (AE1) as a main receptor?
tinyurl.com/3m2rhzj6
#glycotime
#malaria
tinyurl.com/3m2rhzj6
#glycotime
#malaria
November 10, 2025 at 9:17 AM
Plasmodium falciparum and its elusive EBA-181 red blood cell ligand: requires Neu5Ac or Neu5Gc, with Band 3/anion exchanger 1 (AE1) as a main receptor?
tinyurl.com/3m2rhzj6
#glycotime
#malaria
tinyurl.com/3m2rhzj6
#glycotime
#malaria
Italy, Belluno province. Monte Piana (2324 m), World War I monument.
📷Canon EOS 5
🔘17-40 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomites
📷Canon EOS 5
🔘17-40 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomites
November 10, 2025 at 8:53 AM
Italy, Belluno province. Monte Piana (2324 m), World War I monument.
📷Canon EOS 5
🔘17-40 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomites
📷Canon EOS 5
🔘17-40 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomites
Südtirol/Alto Adige. Strudelkopf/Monte Specie (2307).
📷Canon EOS 5
🔘70-300 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomiti
📷Canon EOS 5
🔘70-300 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomiti
November 8, 2025 at 5:03 PM
Südtirol/Alto Adige. Strudelkopf/Monte Specie (2307).
📷Canon EOS 5
🔘70-300 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomiti
📷Canon EOS 5
🔘70-300 mm
🎞️Ilford HP5+
#BelieveInFilm
#Dolomiti
Reposted by Marcin Czerwinski
"World's first potential trillionaire has killed 600,000 people, including 400,000 children" is the only headline that anyone should ever read about Elon Musk
One analytical model shows that, as of November 5th, the dismantling of U.S.A.I.D. has already caused the deaths of 600,000 people, two-thirds of them children. https://newyorkermag.visitlink.me/jUzNSc
The Shutdown of U.S.A.I.D. Has Already Killed Hundreds of Thousands
The short documentary “Rovina’s Choice” tells the story of what goes when aid goes.
newyorkermag.visitlink.me
November 7, 2025 at 1:33 AM
"World's first potential trillionaire has killed 600,000 people, including 400,000 children" is the only headline that anyone should ever read about Elon Musk
Reposted by Marcin Czerwinski
Sweet new #glycotime science out of the Huang lab looking at roles of glyco in the placenta.🧪🧪
Check out my newest paper examining the role of the glycan-binding protein galectin-3 in placental syncytialization! We show that galectin-3 interacts with a glycan at a non-canonical N-X-C site on CD9 to promote placental cell fusion! #glycotime www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
November 4, 2025 at 8:27 PM
Sweet new #glycotime science out of the Huang lab looking at roles of glyco in the placenta.🧪🧪
November 4, 2025 at 8:05 PM
Reposted by Marcin Czerwinski
What happens if your asexual reproduction goes wrong? For instance, you can grow a head instead of a tail. But if you're a flatworm, it's not that bad - as we showed in our newest paper published in the Proceedings of the Royal Society B: tinyurl.com/4dnp2ffz
October 29, 2025 at 2:53 PM
What happens if your asexual reproduction goes wrong? For instance, you can grow a head instead of a tail. But if you're a flatworm, it's not that bad - as we showed in our newest paper published in the Proceedings of the Royal Society B: tinyurl.com/4dnp2ffz
October 29, 2025 at 6:28 PM
Another great paper from @jeffcolgren.bsky.social and @pawelburkhardt.bsky.social. Must-read for everyone interested in the evolution of neurons!
#neuroscience
#neuroscience
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 7:06 PM
Another great paper from @jeffcolgren.bsky.social and @pawelburkhardt.bsky.social. Must-read for everyone interested in the evolution of neurons!
#neuroscience
#neuroscience
Tahkuna, Hiiumaa Island, Estonia. Memorial to the victims of the Estonia ferry disaster, which took the lives of 852 people in 1994.
📷Minolta X-300
🔘28 mm
🎞️Ilford FP4+
#BelieveInFilm
📷Minolta X-300
🔘28 mm
🎞️Ilford FP4+
#BelieveInFilm
October 23, 2025 at 4:19 PM
Tahkuna, Hiiumaa Island, Estonia. Memorial to the victims of the Estonia ferry disaster, which took the lives of 852 people in 1994.
📷Minolta X-300
🔘28 mm
🎞️Ilford FP4+
#BelieveInFilm
📷Minolta X-300
🔘28 mm
🎞️Ilford FP4+
#BelieveInFilm
October 20, 2025 at 6:29 PM
Vilnius, Rasų kapinės/Wilno, cmentarz na Rossie.
📷Bronica ETRS
🔘150 mm
🎞️Ilford Delta 100
#BelieveInFilm
📷Bronica ETRS
🔘150 mm
🎞️Ilford Delta 100
#BelieveInFilm
October 17, 2025 at 7:51 PM
Vilnius, Rasų kapinės/Wilno, cmentarz na Rossie.
📷Bronica ETRS
🔘150 mm
🎞️Ilford Delta 100
#BelieveInFilm
📷Bronica ETRS
🔘150 mm
🎞️Ilford Delta 100
#BelieveInFilm
Interesting review from Richard Cummings lab about N- and O-glycosylation of brain cell surface glycoproteins. Role in brain development and neuronal functions, spatial distribution, CDG. Must-read!
tinyurl.com/ybbnb4x6
#glycotime
tinyurl.com/ybbnb4x6
#glycotime
October 16, 2025 at 9:39 AM
Interesting review from Richard Cummings lab about N- and O-glycosylation of brain cell surface glycoproteins. Role in brain development and neuronal functions, spatial distribution, CDG. Must-read!
tinyurl.com/ybbnb4x6
#glycotime
tinyurl.com/ybbnb4x6
#glycotime
Loss of O-GlcNAcylation in cardiac myocytes triggers the integrated stress response contributing to heart failure
tinyurl.com/58m9ruyc
#glycotime
tinyurl.com/58m9ruyc
#glycotime
October 15, 2025 at 8:37 AM
Loss of O-GlcNAcylation in cardiac myocytes triggers the integrated stress response contributing to heart failure
tinyurl.com/58m9ruyc
#glycotime
tinyurl.com/58m9ruyc
#glycotime