Christa Buecker
@chribue.bsky.social
Molecular Biologist, Transcription enthusiast and stem cell afficionado
Associate Professor at Max Perutz Labs and University Vienna,
Associate Professor at Max Perutz Labs and University Vienna,
Reposted by Christa Buecker
Engineered chromatin readers track damaged chromatin dynamics in live cells and animals
->Nature | More from Lil Dr Glen EcoChat at BigEarthData.ai
->Nature | More from Lil Dr Glen EcoChat at BigEarthData.ai
Engineered chromatin readers track damaged chromatin dynamics in live cells and animals
All singleton BRCT domains from Mus musculus (Fig. 1a) were manually retrieved from Uniprot. Tandem BRCT domains, comprising two or more closely located BRCT domains linked by a variable linker region, were manually retrieved, and their association in tandem was...
www.nature.com
November 22, 2025 at 11:46 AM
It was cold and wet, but nevertheless the lab retreat to Budapest was a success!
November 21, 2025 at 3:41 PM
It was cold and wet, but nevertheless the lab retreat to Budapest was a success!
We are excited to participate this year again in the VBC summer school! If you want to work with me and my amazing student Maria, apply!
The Vienna BioCenter Summer School 2026 call is now open for talented undergrads, it's a great opportunity for students who are interested in graduate study in the life sciences. Christa Buecker from Max Perutz Labs Vienna is recruiting! Please share
https://training.vbc.ac.at/summer-school/
https://training.vbc.ac.at/summer-school/
November 21, 2025 at 3:36 PM
We are excited to participate this year again in the VBC summer school! If you want to work with me and my amazing student Maria, apply!
Congratulations again, Clemens!
Messenger RNA is made in the nucleus before it is exported to the cytoplasm for translation. But how are only correctly made mRNAs chosen and remodeled in the nucleus for export?
Our new paper investigates the nuclear events leading to human mRNA export. www.nature.com/articles/s41.... (1/4)
Our new paper investigates the nuclear events leading to human mRNA export. www.nature.com/articles/s41.... (1/4)
November 21, 2025 at 7:49 AM
Congratulations again, Clemens!
I teach quite a bit, but today was my favourite yearly teaching event: a seminar with @clemensplaschka.bsky.social and @ursulaschoeberl.bsky.social on initiation of transcription, either from a single-molecule or a structural perspective. So much fun and so many insights!
November 18, 2025 at 4:09 PM
I teach quite a bit, but today was my favourite yearly teaching event: a seminar with @clemensplaschka.bsky.social and @ursulaschoeberl.bsky.social on initiation of transcription, either from a single-molecule or a structural perspective. So much fun and so many insights!
Congratulations, @alex-stark.bsky.social and @miketilapia.bsky.social ! Loved hearing everything during the @cshasia.bsky.social
Major new direction in the lab: hacking human cell biology with pathogen effectors (eORFs) - amazing collaboration with @miketilapia.bsky.social lab. Huge congrats to first authors Tomas & He & all co-authors! Check out the pre-print on @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
www.biorxiv.org
November 18, 2025 at 4:04 PM
Congratulations, @alex-stark.bsky.social and @miketilapia.bsky.social ! Loved hearing everything during the @cshasia.bsky.social
Reposted by Christa Buecker
The Vienna BioCenter Summer School 2026 call is now open for talented undergrads, it's a great opportunity for students who are interested in graduate study in the life sciences. Please RT
https://training.vbc.ac.at/summer-school/
https://training.vbc.ac.at/summer-school/
November 17, 2025 at 3:55 PM
The Vienna BioCenter Summer School 2026 call is now open for talented undergrads, it's a great opportunity for students who are interested in graduate study in the life sciences. Please RT
https://training.vbc.ac.at/summer-school/
https://training.vbc.ac.at/summer-school/
Congratulations, Dr Weykopf! Great achievement andbibambvertain it was a fantastic defense!
A personal milestone - PhD successfully defended (with no corrections 🥳)
A heartfelt thank you to my supervisors @wbickmor.bsky.social @simonbiddie.bsky.social @eliasfriman.bsky.social @KennyBaillie and the entire Bickmore lab who made this a wonderful 4 years ✨
A heartfelt thank you to my supervisors @wbickmor.bsky.social @simonbiddie.bsky.social @eliasfriman.bsky.social @KennyBaillie and the entire Bickmore lab who made this a wonderful 4 years ✨
November 15, 2025 at 7:05 AM
Congratulations, Dr Weykopf! Great achievement andbibambvertain it was a fantastic defense!
Apply!
✨ Passionate about cell biology or biochemistry? Join the Martens Lab as a postdoc to uncover why autophagy stalls at disease-linked protein aggregates - and how to restart it 🧠 Apply here ➡️ tinyurl.com/24dcrcke
November 13, 2025 at 6:23 AM
Apply!
Reposted by Christa Buecker
📣 Paper alert!
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
November 10, 2025 at 11:11 AM
📣 Paper alert!
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
Reposted by Christa Buecker
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Reposted by Christa Buecker
Congratulations to Irene Schwartz, winner of the @viennabiocenter.bsky.social PhD Award! 🧠👏
Her research reveals how cells fine-tune immune balance through protein degradation 🏆 More ➡️ tinyurl.com/2r9c7a5f
@univie.ac.at
@meduniwien.ac.at
Her research reveals how cells fine-tune immune balance through protein degradation 🏆 More ➡️ tinyurl.com/2r9c7a5f
@univie.ac.at
@meduniwien.ac.at
November 10, 2025 at 8:33 AM
Congratulations to Irene Schwartz, winner of the @viennabiocenter.bsky.social PhD Award! 🧠👏
Her research reveals how cells fine-tune immune balance through protein degradation 🏆 More ➡️ tinyurl.com/2r9c7a5f
@univie.ac.at
@meduniwien.ac.at
Her research reveals how cells fine-tune immune balance through protein degradation 🏆 More ➡️ tinyurl.com/2r9c7a5f
@univie.ac.at
@meduniwien.ac.at
Congratulations, Wendy!
So excited to be funded by @erc.europa.eu to work with this extraordinarily talented group of scientists on the GeneMotors project - unravelling how SMC motors work, how they are regulated and how they regulate gene expression.
@ceesdekker.bsky.social @uoe-igc.bsky.social
@ceesdekker.bsky.social @uoe-igc.bsky.social
November 7, 2025 at 2:44 PM
Congratulations, Wendy!
Reposted by Christa Buecker
So excited to be funded by @erc.europa.eu to work with this extraordinarily talented group of scientists on the GeneMotors project - unravelling how SMC motors work, how they are regulated and how they regulate gene expression.
@ceesdekker.bsky.social @uoe-igc.bsky.social
@ceesdekker.bsky.social @uoe-igc.bsky.social
November 7, 2025 at 11:50 AM
So excited to be funded by @erc.europa.eu to work with this extraordinarily talented group of scientists on the GeneMotors project - unravelling how SMC motors work, how they are regulated and how they regulate gene expression.
@ceesdekker.bsky.social @uoe-igc.bsky.social
@ceesdekker.bsky.social @uoe-igc.bsky.social
Reposted by Christa Buecker
This study presents an in vitro analysis of centriole and cilium formation during early mouse embryonic development, using 3D models to mimic implantation, tissue patterning, and axis elongation. @chribue.bsky.social @isabellavoelkl.bsky.social www.life-science-alliance.org/content/9/1/...
November 6, 2025 at 4:04 PM
This study presents an in vitro analysis of centriole and cilium formation during early mouse embryonic development, using 3D models to mimic implantation, tissue patterning, and axis elongation. @chribue.bsky.social @isabellavoelkl.bsky.social www.life-science-alliance.org/content/9/1/...
Reposted by Christa Buecker
Magnus Nordborg of the GMI from the @oeaw.bsky.social has received a Synergy Grant from the @erc.europa.eu. With Richard Durbin and @felipekteixeira.bsky.social, they will investigate how transposable elements shape genome evolution in eukaryotes.
Read more: www.oeaw.ac.at/gmi/news-eve...
Read more: www.oeaw.ac.at/gmi/news-eve...
November 6, 2025 at 11:08 AM
Magnus Nordborg of the GMI from the @oeaw.bsky.social has received a Synergy Grant from the @erc.europa.eu. With Richard Durbin and @felipekteixeira.bsky.social, they will investigate how transposable elements shape genome evolution in eukaryotes.
Read more: www.oeaw.ac.at/gmi/news-eve...
Read more: www.oeaw.ac.at/gmi/news-eve...
Reposted by Christa Buecker
Mechanism of #autophagy initiation by transmembrane selective autophagy receptors
@elias-adriaenssens.bsky.social & @martenslab.bsky.social review emerging mechanistic differences between soluble and transmembrane autophagy receptors
www.embopress.org/doi/full/10....
@elias-adriaenssens.bsky.social & @martenslab.bsky.social review emerging mechanistic differences between soluble and transmembrane autophagy receptors
www.embopress.org/doi/full/10....
November 6, 2025 at 4:20 PM
Mechanism of #autophagy initiation by transmembrane selective autophagy receptors
@elias-adriaenssens.bsky.social & @martenslab.bsky.social review emerging mechanistic differences between soluble and transmembrane autophagy receptors
www.embopress.org/doi/full/10....
@elias-adriaenssens.bsky.social & @martenslab.bsky.social review emerging mechanistic differences between soluble and transmembrane autophagy receptors
www.embopress.org/doi/full/10....
Reposted by Christa Buecker
New paper alert! Scientists in Clemens Plaschka’s lab at the IMP and @juliusbrennecke.bsky.social's lab at
@imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
@imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
November 6, 2025 at 4:04 PM
New paper alert! Scientists in Clemens Plaschka’s lab at the IMP and @juliusbrennecke.bsky.social's lab at
@imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
@imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
Congratulation, @martenslab.bsky.social! great colleague and awesome scientist, now with his third ERC grant!
Big news! Group leader Sascha Martens has been awarded a prestigious @erc.europa.eu Synergy Grant for the collaborative project DegrAbility to explore how cells can better recycle harmful protein aggregates linked to diseases like Alzheimer’s ➡️ tinyurl.com/2zuz9jcf
@univie.ac.at
@meduniwien.ac.at
@univie.ac.at
@meduniwien.ac.at
November 6, 2025 at 3:39 PM
Congratulation, @martenslab.bsky.social! great colleague and awesome scientist, now with his third ERC grant!
And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
November 6, 2025 at 4:35 AM
And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu
October 31, 2025 at 9:25 AM
Reposted by Christa Buecker
Our latest review is now online! 👇
@martenslab.bsky.social
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal www.embopress.org/doi/full/10....
@martenslab.bsky.social
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal www.embopress.org/doi/full/10....
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
October 31, 2025 at 6:24 AM
Our latest review is now online! 👇
@martenslab.bsky.social
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal www.embopress.org/doi/full/10....
@martenslab.bsky.social
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal www.embopress.org/doi/full/10....
Reposted by Christa Buecker
This exciting study by the Buecker lab @chribue.bsky.social & first author Isabella Voelkl @isabellavoelkl.bsky.social explores in vitro differentiation models for their usability in studying cilia and centriole formation in mouse embryonic development www.life-science-alliance.org/content/9/1/...
October 30, 2025 at 3:05 PM
This exciting study by the Buecker lab @chribue.bsky.social & first author Isabella Voelkl @isabellavoelkl.bsky.social explores in vitro differentiation models for their usability in studying cilia and centriole formation in mouse embryonic development www.life-science-alliance.org/content/9/1/...
Reposted by Christa Buecker
I’m deeply grateful to my supervisor @chribue.bsky.social, Alexander Dammermann, Martin Leeb and all colleagues and collaborators for their support throughout this journey. Thank you @vbcscitraining.bsky.social and @maxperutzlabs.ac.at for providing such a stimulating scientific environment.
October 30, 2025 at 9:34 AM
I’m deeply grateful to my supervisor @chribue.bsky.social, Alexander Dammermann, Martin Leeb and all colleagues and collaborators for their support throughout this journey. Thank you @vbcscitraining.bsky.social and @maxperutzlabs.ac.at for providing such a stimulating scientific environment.
Really excited to see this out in the open: www.life-science-alliance.org/content/9/1/...! @isabellavoelkl.bsky.social explored and compared different in vitro developmental model systems to study ciliogenesis.
In vitro approaches to study centriole and cilium function in early mouse embryogenesis
Although centrioles and primary cilia play an essential role in early mammalian development, their specific function during the interval between their initial formation and the subsequent arrest of em...
www.life-science-alliance.org
October 30, 2025 at 9:17 AM
Really excited to see this out in the open: www.life-science-alliance.org/content/9/1/...! @isabellavoelkl.bsky.social explored and compared different in vitro developmental model systems to study ciliogenesis.