Center for Immunology-UMN
@cfi-umn.bsky.social
The Center for Immunology at the University of Minnesota Medical School is driven to make discoveries about the immune system that improve human health and well-being.
Website: immunology.umn.edu
LinkedIn: www.linkedin.com/in/immunology/
X: x.com/CFI_UMN
Website: immunology.umn.edu
LinkedIn: www.linkedin.com/in/immunology/
X: x.com/CFI_UMN
This Thanksgiving, the CFI community extends our heartfelt gratitude to our trainees, faculty, staff, collaborators, and alumni.
Your dedication drives discovery, strengthens our mission, and advances the future of immunology.
We are thankful for all you do.
Wishing you a restful and joyful holiday.
Your dedication drives discovery, strengthens our mission, and advances the future of immunology.
We are thankful for all you do.
Wishing you a restful and joyful holiday.
a greeting card that says happy thanksgiving
ALT: a greeting card that says happy thanksgiving
media.tenor.com
November 27, 2025 at 5:05 PM
This Thanksgiving, the CFI community extends our heartfelt gratitude to our trainees, faculty, staff, collaborators, and alumni.
Your dedication drives discovery, strengthens our mission, and advances the future of immunology.
We are thankful for all you do.
Wishing you a restful and joyful holiday.
Your dedication drives discovery, strengthens our mission, and advances the future of immunology.
We are thankful for all you do.
Wishing you a restful and joyful holiday.
In their new editorial, Carla Rothlin and J. S. Gutkind present a Special Collection on Targeting the Immune System, covering advances in cancer immunology, chronic inflammation, neuroimmune biology, addiction immunotherapy, and regenerative immunity.
jpet.aspetjournals.org/article/S002...
jpet.aspetjournals.org/article/S002...
A special collection on targeting the immune system—Editorial
We have recently witnessed a revolution in our ability to modulate the immune system
to increase the recognition and destruction of infectious agents and cancer cells,
as well as to selectively dampen...
jpet.aspetjournals.org
November 27, 2025 at 2:23 AM
In their new editorial, Carla Rothlin and J. S. Gutkind present a Special Collection on Targeting the Immune System, covering advances in cancer immunology, chronic inflammation, neuroimmune biology, addiction immunotherapy, and regenerative immunity.
jpet.aspetjournals.org/article/S002...
jpet.aspetjournals.org/article/S002...
New from Masopust, Ahmed, and colleagues!
A major multi-lab Consensus Statement offering updated, field-wide guidelines for defining and reporting T cell populations, bringing clarity, consistency, and transparency to T cell research.
nature.com/articles/s41...
A major multi-lab Consensus Statement offering updated, field-wide guidelines for defining and reporting T cell populations, bringing clarity, consistency, and transparency to T cell research.
nature.com/articles/s41...
Guidelines for T cell nomenclature - Nature Reviews Immunology
This Consensus Statement clarifies the existing subset-based nomenclature for T cells. Furthermore, it proposes an alternative modular nomenclature that is designed to be brief and flexible and to avo...
nature.com
November 21, 2025 at 6:28 PM
New from Masopust, Ahmed, and colleagues!
A major multi-lab Consensus Statement offering updated, field-wide guidelines for defining and reporting T cell populations, bringing clarity, consistency, and transparency to T cell research.
nature.com/articles/s41...
A major multi-lab Consensus Statement offering updated, field-wide guidelines for defining and reporting T cell populations, bringing clarity, consistency, and transparency to T cell research.
nature.com/articles/s41...
Congrats to the Stromnes Lab: Adam Burrack, Alex Tsai, Madeline Ellefson, Zoe Schmiechen, Brandon Larsen, Kristina Burrack, and Ingunn Stromnes on their new paper showing IL15 complex enhances anti–PDL1 therapy in PDA via sustained T cell function.
pubmed.ncbi.nlm.nih.gov/41254224/
pubmed.ncbi.nlm.nih.gov/41254224/
IL-15 complex enhances therapeutic efficacy of anti-PD-L1 in a T cell–dependent and NK cell–independent manner in a murine model of pancreatic ductal adenocarcinoma
Abstract. Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy resistant to therapy including immune checkpoint blockade (ICB). We previously show
academic.oup.com
November 21, 2025 at 6:01 PM
Congrats to the Stromnes Lab: Adam Burrack, Alex Tsai, Madeline Ellefson, Zoe Schmiechen, Brandon Larsen, Kristina Burrack, and Ingunn Stromnes on their new paper showing IL15 complex enhances anti–PDL1 therapy in PDA via sustained T cell function.
pubmed.ncbi.nlm.nih.gov/41254224/
pubmed.ncbi.nlm.nih.gov/41254224/
Congratulations to the Freedman Lab and MD/PhD student Anders Lindstedt on this exciting new JLB paper! A fantastic team effort with the Williams Lab-well done! 👏🧪
New publication: "Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent manner" is out now in JLB. MD/PhD student Anders Lindstedt led with an assist from @lab-williams.bsky.social. academic.oup.com/jleukbio/art... @cfi-umn.bsky.social 🧪
Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent manner
RNA sequencing and functional assays demonstrate that both LynA and LynB restrict macrophage proliferation and drive TLR-induced ECM remodeling and inflamm
academic.oup.com
November 18, 2025 at 4:25 PM
Congratulations to the Freedman Lab and MD/PhD student Anders Lindstedt on this exciting new JLB paper! A fantastic team effort with the Williams Lab-well done! 👏🧪
Congratulations to T. Dileepan on the publication of his collaborative work with Jennifer Gommerman’s group in Cell, uncovering how TFH1 cells and B-cell MHC class II signaling drive protective IgA responses during mucosal viral infection: www.cell.com/cell/abstrac...
www.cell.com
November 18, 2025 at 4:10 PM
Congratulations to T. Dileepan on the publication of his collaborative work with Jennifer Gommerman’s group in Cell, uncovering how TFH1 cells and B-cell MHC class II signaling drive protective IgA responses during mucosal viral infection: www.cell.com/cell/abstrac...
Yesterday was #WorldScienceDay — but honestly, every day is science day here at CFI. 🧬💙
We’re proud to be part of a global community that builds trust, shares knowledge, and pushes discovery forward.
We’re proud to be part of a global community that builds trust, shares knowledge, and pushes discovery forward.
November 11, 2025 at 1:36 PM
Yesterday was #WorldScienceDay — but honestly, every day is science day here at CFI. 🧬💙
We’re proud to be part of a global community that builds trust, shares knowledge, and pushes discovery forward.
We’re proud to be part of a global community that builds trust, shares knowledge, and pushes discovery forward.
Reposted by Center for Immunology-UMN
Vobořil, Hogquist @cfi-umn.bsky.social and colleagues reveal the #thymus as a niche for diverse, developmentally distinct #myeloid cells and elucidate their specific requirements for development and maturation. rupress.org/jem/article/...
#Hematopoiesis #Tolerance #LymphocyteBiology
#Hematopoiesis #Tolerance #LymphocyteBiology
November 5, 2025 at 8:30 PM
Vobořil, Hogquist @cfi-umn.bsky.social and colleagues reveal the #thymus as a niche for diverse, developmentally distinct #myeloid cells and elucidate their specific requirements for development and maturation. rupress.org/jem/article/...
#Hematopoiesis #Tolerance #LymphocyteBiology
#Hematopoiesis #Tolerance #LymphocyteBiology
Science builds trust and shapes tomorrow. On #WorldScienceDay, Dr. Carla Rothlin, IUIS Vice-President and CFI Director, joins global voices for the IUIS Roundtable — “Trust, Transformation, and Tomorrow.”
🌍 Nov 10 | 9:00 am (CST)
Register here: immunohub.iuis.org/b2726748afc1...
🌍 Nov 10 | 9:00 am (CST)
Register here: immunohub.iuis.org/b2726748afc1...
This #WorldScienceDay, IUIS joins the @sciencecouncil.bsky.social & the global scientific community in celebrating science as a force for trust, collaboration & progress.
Nov 10 | 16:00 CET
🎥 Live on #ImmunoHub
https://loom.ly/2PZA5YI
Nov 10 | 16:00 CET
🎥 Live on #ImmunoHub
https://loom.ly/2PZA5YI
November 4, 2025 at 5:49 PM
Science builds trust and shapes tomorrow. On #WorldScienceDay, Dr. Carla Rothlin, IUIS Vice-President and CFI Director, joins global voices for the IUIS Roundtable — “Trust, Transformation, and Tomorrow.”
🌍 Nov 10 | 9:00 am (CST)
Register here: immunohub.iuis.org/b2726748afc1...
🌍 Nov 10 | 9:00 am (CST)
Register here: immunohub.iuis.org/b2726748afc1...
Reposted by Center for Immunology-UMN
AAI member Carla Rothlin, PhD, was elected vice-president of @iuis-online.bsky.social at the 2025 IUIS Congress. While moving her lab to the University of Minnesota to direct the Center for Immunology, Dr. Rothlin generously took the time to answer some questions for us: ow.ly/PG7N50WWL4Q. #AAInews
Carla Rothlin Elected IUIS Vice-President - AAI News
AAI Member Carla Rothlin was recently elected vice-president of the International Union of Immunological Societies
ow.ly
September 15, 2025 at 6:05 PM
AAI member Carla Rothlin, PhD, was elected vice-president of @iuis-online.bsky.social at the 2025 IUIS Congress. While moving her lab to the University of Minnesota to direct the Center for Immunology, Dr. Rothlin generously took the time to answer some questions for us: ow.ly/PG7N50WWL4Q. #AAInews
Join us Friday, Oct 17th, 2025 for Anders Linstedt's MICaB Final Ph.D. Defense: "Lyn kinase controls Toll-like receptor signaling in a cell-specific, isoform-independent manner" Advisor: Tanya Freedman(@tfreedmanlab.bsky.social), 9:00 am, 1-110 LRB/MTRF or Zoom info at immunology.umn.edu
October 14, 2025 at 5:23 PM
Join us Friday, Oct 17th, 2025 for Anders Linstedt's MICaB Final Ph.D. Defense: "Lyn kinase controls Toll-like receptor signaling in a cell-specific, isoform-independent manner" Advisor: Tanya Freedman(@tfreedmanlab.bsky.social), 9:00 am, 1-110 LRB/MTRF or Zoom info at immunology.umn.edu
With deep gratitude, we thank Dr. Marc Jenkins for his decades of leadership, mentorship, and dedication to the Center for Immunology. The foundation he built will guide and inspire us for years to come.
August 25, 2025 at 12:06 PM
With deep gratitude, we thank Dr. Marc Jenkins for his decades of leadership, mentorship, and dedication to the Center for Immunology. The foundation he built will guide and inspire us for years to come.
🎉 Congratulations to Dr. Carla Rothlin, incoming Director of CFI, on her election as Vice-President of the International Union of Immunological Societies (IUIS)! A tremendous honor and a testament to her leadership in the global immunology community. 🌍🧪
August 21, 2025 at 1:56 PM
🎉 Congratulations to Dr. Carla Rothlin, incoming Director of CFI, on her election as Vice-President of the International Union of Immunological Societies (IUIS)! A tremendous honor and a testament to her leadership in the global immunology community. 🌍🧪
Reposted by Center for Immunology-UMN
Our latest paper, Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages, is online at Communications Biology. Collaboration with the Ivanov and Revelo labs. @cfi-umn.bsky.social
rdcu.be/esUdT
rdcu.be/esUdT
Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages
Communications Biology - Transcriptional analysis of lipid associated macrophages across chronic inflammatory diseases and tissues reveals shared and tissue-restricted gene expression programs.
rdcu.be
June 23, 2025 at 1:21 PM
Our latest paper, Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages, is online at Communications Biology. Collaboration with the Ivanov and Revelo labs. @cfi-umn.bsky.social
rdcu.be/esUdT
rdcu.be/esUdT
We’re thrilled to welcome Dr. Carla Rothlin as our new Director of the Center for Immunology and Dr. Sourav Ghosh as CFI Program director, Immunology of Tissue Resolution, Repair, & Regeneration at UMN! Both join us from Yale and officially start in August 2025.
June 24, 2025 at 1:59 PM
We’re thrilled to welcome Dr. Carla Rothlin as our new Director of the Center for Immunology and Dr. Sourav Ghosh as CFI Program director, Immunology of Tissue Resolution, Repair, & Regeneration at UMN! Both join us from Yale and officially start in August 2025.
Huge congratulations to @lab-williams.bsky.social
on your well-deserved promotion to Associate Professor! 🎉 We're so proud to call you a colleague, your hard work and leadership truly shine. Excited for all that’s ahead!
on your well-deserved promotion to Associate Professor! 🎉 We're so proud to call you a colleague, your hard work and leadership truly shine. Excited for all that’s ahead!
May 18, 2025 at 2:50 PM
Huge congratulations to @lab-williams.bsky.social
on your well-deserved promotion to Associate Professor! 🎉 We're so proud to call you a colleague, your hard work and leadership truly shine. Excited for all that’s ahead!
on your well-deserved promotion to Associate Professor! 🎉 We're so proud to call you a colleague, your hard work and leadership truly shine. Excited for all that’s ahead!
Congratulations to Zoe Schmiechen!
All of us at CFI are thrilled to celebrate Zoe Schmiechen for an incredible achievement—winning not one, not two, but three prestigious trainee awards this semester! 🎉
All of us at CFI are thrilled to celebrate Zoe Schmiechen for an incredible achievement—winning not one, not two, but three prestigious trainee awards this semester! 🎉
May 5, 2025 at 6:17 PM
Congratulations to Zoe Schmiechen!
All of us at CFI are thrilled to celebrate Zoe Schmiechen for an incredible achievement—winning not one, not two, but three prestigious trainee awards this semester! 🎉
All of us at CFI are thrilled to celebrate Zoe Schmiechen for an incredible achievement—winning not one, not two, but three prestigious trainee awards this semester! 🎉
CFI at AAI 2025 having a great time.
May 4, 2025 at 11:16 PM
CFI at AAI 2025 having a great time.
🔬 Meet the Stromnes Lab (@IngunnStromnes)!
Part of CFI & the Center for Genome Engineering, they’re engineering T cells to take on one of the toughest cancers out there: pancreatic cancer.
They’re pushing the limits of immunotherapy, and it’s just the beginning.
👉 sites.google.com/umn.edu/stro...
Part of CFI & the Center for Genome Engineering, they’re engineering T cells to take on one of the toughest cancers out there: pancreatic cancer.
They’re pushing the limits of immunotherapy, and it’s just the beginning.
👉 sites.google.com/umn.edu/stro...
May 2, 2025 at 2:12 PM
🔬 Meet the Stromnes Lab (@IngunnStromnes)!
Part of CFI & the Center for Genome Engineering, they’re engineering T cells to take on one of the toughest cancers out there: pancreatic cancer.
They’re pushing the limits of immunotherapy, and it’s just the beginning.
👉 sites.google.com/umn.edu/stro...
Part of CFI & the Center for Genome Engineering, they’re engineering T cells to take on one of the toughest cancers out there: pancreatic cancer.
They’re pushing the limits of immunotherapy, and it’s just the beginning.
👉 sites.google.com/umn.edu/stro...
Reposted by Center for Immunology-UMN
⌛ The countdown to #IMMUNOLOGY2025 is on!
Get ready for the meeting by listening to @aai.org President Dr. Stephen Jameson and @immunohorizons.bsky.social Editor-in-Chief Dr. Bonnie Dittel discuss the highlights of this year's program: bit.ly/3Rs5zY1
#AAI2025
Get ready for the meeting by listening to @aai.org President Dr. Stephen Jameson and @immunohorizons.bsky.social Editor-in-Chief Dr. Bonnie Dittel discuss the highlights of this year's program: bit.ly/3Rs5zY1
#AAI2025
Ep. 101: "IMMUNOLOGY2025™" Featuring Drs. Stephen Jameson and Bonnie Dittel - The Immunology Podcast
Dr. Stephen Jameson is the President of the American Association of Immunologists, and LMP Professor and Harry Kay Chairman's Fund Professor in Experimental Pathology at the University of Minnesota Tw...
bit.ly
April 17, 2025 at 8:06 PM
⌛ The countdown to #IMMUNOLOGY2025 is on!
Get ready for the meeting by listening to @aai.org President Dr. Stephen Jameson and @immunohorizons.bsky.social Editor-in-Chief Dr. Bonnie Dittel discuss the highlights of this year's program: bit.ly/3Rs5zY1
#AAI2025
Get ready for the meeting by listening to @aai.org President Dr. Stephen Jameson and @immunohorizons.bsky.social Editor-in-Chief Dr. Bonnie Dittel discuss the highlights of this year's program: bit.ly/3Rs5zY1
#AAI2025
Reposted by Center for Immunology-UMN
The recorded video of Dr. Marc Jenkins seminar entitled The CD4+ T cell response to food: you aren't what you eat is now available at “Global Immunotalks” YouTube Channel youtube.com/live/zPLBJT1...
Please ask questions in the Youtube comment section for Marc.
Hope you enjoy it!
Please ask questions in the Youtube comment section for Marc.
Hope you enjoy it!
"The CD4+ T cell response to food: you aren't what you eat" by Dr. Marc Jenkins
YouTube video by GLOBAL IMMUNOTALKS
youtube.com
March 26, 2025 at 6:02 PM
The recorded video of Dr. Marc Jenkins seminar entitled The CD4+ T cell response to food: you aren't what you eat is now available at “Global Immunotalks” YouTube Channel youtube.com/live/zPLBJT1...
Please ask questions in the Youtube comment section for Marc.
Hope you enjoy it!
Please ask questions in the Youtube comment section for Marc.
Hope you enjoy it!
CFI welcomes Jim Zimring as our next Spring 2025 Immunology MICaB Invited Speaker. Join us today at noon in person (1-125 CCRB) to hear his talk on "The Role of Linked Recognition in Alloimmunization to Transfused RBCs and the B cell Precursor Frequency Hypothesis."
April 14, 2025 at 12:37 PM
CFI welcomes Jim Zimring as our next Spring 2025 Immunology MICaB Invited Speaker. Join us today at noon in person (1-125 CCRB) to hear his talk on "The Role of Linked Recognition in Alloimmunization to Transfused RBCs and the B cell Precursor Frequency Hypothesis."
Reposted by Center for Immunology-UMN
Have you booked your hotel for #IMMUNOLOGY2025™? In partnership with onPeak, AAI has secured discounted rates at a selection of Honolulu hotels. Reserve your room now: ow.ly/zFBn50VcUE5.
April 8, 2025 at 2:18 PM
Have you booked your hotel for #IMMUNOLOGY2025™? In partnership with onPeak, AAI has secured discounted rates at a selection of Honolulu hotels. Reserve your room now: ow.ly/zFBn50VcUE5.
🗓️ Save the Date!🗓️
Join us for the 2025 Blumenthal Memorial Lectureship Series featuring Jenny Ting, Ph.D. on April 25, 2025, from 12:00 PM - 1:00 PM at 2-620 Moos Tower.
Don’t miss this exciting talk! To save to your calendar: z.umn.edu/2025_Blument...
Join us for the 2025 Blumenthal Memorial Lectureship Series featuring Jenny Ting, Ph.D. on April 25, 2025, from 12:00 PM - 1:00 PM at 2-620 Moos Tower.
Don’t miss this exciting talk! To save to your calendar: z.umn.edu/2025_Blument...
April 7, 2025 at 7:02 PM
🗓️ Save the Date!🗓️
Join us for the 2025 Blumenthal Memorial Lectureship Series featuring Jenny Ting, Ph.D. on April 25, 2025, from 12:00 PM - 1:00 PM at 2-620 Moos Tower.
Don’t miss this exciting talk! To save to your calendar: z.umn.edu/2025_Blument...
Join us for the 2025 Blumenthal Memorial Lectureship Series featuring Jenny Ting, Ph.D. on April 25, 2025, from 12:00 PM - 1:00 PM at 2-620 Moos Tower.
Don’t miss this exciting talk! To save to your calendar: z.umn.edu/2025_Blument...
🎉CFI congratulates Dr. Alexander Khoruts on the Distinguished McKnight University Professorship! His pioneering microbiome research is revolutionizing treatments for C. diff, autoimmune diseases, and cancer. 👏👏
April 2, 2025 at 6:49 PM
🎉CFI congratulates Dr. Alexander Khoruts on the Distinguished McKnight University Professorship! His pioneering microbiome research is revolutionizing treatments for C. diff, autoimmune diseases, and cancer. 👏👏